Triple dose of gadolinium-DTPA and delayed MRI in patients with benign multiple sclerosis

Journal of Neurology Neurosurgery and Psychiatry

Volumn 60, Issue 5, 1996, Pages 526-530

  Filippi, M ^a,c   Capra, R ^b   Campi, A ^a   Colombo, B ^a   Prandini, F ^b   Marciano, N ^b   Gasparotti, R ^b   Comi, G ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Benign multiple sclerosis; Delayed MRI; Imaging; Magnetic resonance; Triple dose gadolinium DTPA

Indexed keywords

GADOLINIUM PENTETATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTRAST; DIAGNOSTIC VALUE; DISABILITY; DISEASE DURATION; HUMAN; MULTICENTER STUDY; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0029980586     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.60.5.526     Document Type: Article

References (25)

1. Weinshenker BG. The natural history of multiple sclerosis. Neurol Clin 1995;13:119-46.
2. Thompson AJ, Kermode AG, MacManus DG, et al. Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study. BMJ 1990;300: 631-4.
3. Thompson AJ, Miller D, Youl B, et al. Serial gadolinium-enhanced MRI in relapsing-remitting multiple sclerosis of varying disease duration. Neurology 1992;42:60-3.
4. Kidd D, Thompson AJ, Kendall BE, Miller DH, McDonald WI. Benign form of multiple sclerosis: MRI evidence for less frequent and less inflammatory disease activity. J Neurol Neurosurg Psychiatry 1994;57:1070-2.
5. Filippi M, Campi A, Martinelli V, et al. Comparison of triple dose versus standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with primary progressive multiple sclerosis. J Neurol Neurosurg Psychiatry 1995;59:540-4.
6. Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI. A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 1994;117: 759-65.
7. Kermode AG, Tofts PS, Thompson AJ, et al. Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement. Neurology 1990;40:229-35.
8. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. Fundamental concepts. Magn Reson Med 1991;17:357-67.
9. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-52.
10. Miller DH, Barkhof F, Berry I, Kappos L, Scotti G, Thompson AJ. Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines. J Neurol Neurosurg Psychiatry 1991;54:683-8.
11. Wicks DAG, Tofts PS, Miller DH, et al. Volume measurements of multiple sclerosis lesions with magnetic resonance images: a preliminary study. Neuroradiology 1992;34:475-9.
12. Filippi M, Horsfield MA, Morrissey SP, et al. Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. Neurology 1994;44:635-11.
13. Vinuela FV, Fox AJ, Debrun GM, Feasby TE, Ebers GC. New perspectives in computed tomography of multiple sclerosis. AJNR Am J Neuroradiol 1982;3:277-81.
14. Sears S, McCammon A, Bigelow R, Hayman LA. Maximizing the harvest of contrast enhancing lesions in multiple sclerosis. Neurology 1982;32:815-20.
15. Spiegel SM, Vinuela F, Fox AJ, Pelz DM. CT of multiple sclerosis: reassessment of delayed scanning with high doses of contrast material. AJR Am J Roentgenol 1985;145:497-500.
16. Filippi M, Yousry T, Campi A, et al. Comparison of triple dose versus standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with multiple sclerosis. Neurology 1996 (in press).
17. Filippi M, Barker GJ, Horsfield MA, et al. A quantitative brain MRI study of benign and secondary progressive multiple sclerosis. J Neurol 1994;241:246-51.
18. Gass A, Barker GJ, Kidd D, et al. Correlation of magnetisation transfer ratio with clinical disability in multiple sclerosis. Ann Neurol 1994;36:62-7.
19. Filippi M, Campi A, Dousset V, et al. A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis. Neurology 1995;45:478-82.
20. 1-weighted") spin-echo images. Neurology 1995;45:1684-90.
21. Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology 1993;43:2632-7.
22. McDonald WI, Miller DH, Barnes D. The pathological evolution of multiple sclerosis. Neuropathol Appl Neurobiol 1992;18:319-34.
23. Gerard G, Weisberg LA. MRI periventricular lesions in adults. Neurology 1986;36:998-1001.
24. Stone LA, Frank JA, Albert PS, et al. The effect of interferon-beta on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis. Ann Neurol 1995;37:611-9.
25. Smith ME, Stone LA, Albert PS, et al. Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine-enhancing magnetic resonance imaging lesions. Ann Neurol 1993;33:480-9.