Sensory irritation mechanisms investigated from model compounds: Trifluoroethanol, hexafluoroisopropanol and methyl hexafluoroisopropyl ether

Archives of Toxicology

Volumn 70, Issue 6, 1996, Pages 319-328

  Nielsen, Gunnar D ^a   Abraham, Michael H ^b   Hansen, Lea F ^a   Hammer, Maria ^a   Cooksey, Christopher J ^b   Andonian Haftvan, Jenik ^b   Alarie, Yves ^c  

^a NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Bronsted acid; Coupled reaction; Hexafluoroisopropanol; Hydrogen bonding; Methyl hexafluoroisopropyl ester; Mice; Receptor; Sensory irritation; Trifluoroethanol

Indexed keywords

HEXAFLUORISOPROPANOL; METHYL HEXAFLUORISOPROPYL ETHER; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING RATE; CONTROLLED STUDY; HYDROGEN BOND; INHALATION; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION;

1-PROPANOL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; IRRITANTS; MALE; METHYL ETHERS; MICE; MICE, INBRED STRAINS; MODELS, CHEMICAL; PROPANOLS; RESPIRATION; TRIFLUOROETHANOL;

EID: 0029980371     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050281     Document Type: Article

References (32)

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