Complement: instructing the acquired immune system through the CD21/CD19 complex

Research in Immunology

Volumn 147, Issue 2, 1996, Pages 71-75

  Dempsey, P W ^a   Fearon, D T ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; COMPLEMENT RECEPTOR;

AUTOIMMUNITY; B LYMPHOCYTE; CONFERENCE PAPER; ETIOLOGY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029980169     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2494(96)87176-8     Document Type: Article

References (34)

1. CD28-B7 interactions in T-cell activation
2. Guinea pigs with inherited deficiencies of complement components C2 or C4 have characteristics of immune complex disease
3. Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM
4. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes
5. Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes
6. The CD19 complex of B lymphocytes. Activation of phospholipase C by a protein tyrosine kinase-dependent pathway that can be enhanced by the IgM complex
7. Complement deficiency and immune complex disease
8. C3d of complement as a molecular adjuvant bridging innate and acquired immunity
9. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
10. The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity
11. Comparative structure and evolution of murine CR2. The homologue of human C3d/EBV receptor (CD21)
12. B cells turn off virgin but not memory T cells
13. Identification of an alternative CTLA-4 ligand costimulatory for T cell activation
14. Suppression of the immune response by a soluble complement receptor of B lymphocytes
15. In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody
16. Approaching the asymptote? Evolution and revolution in immunology
17. Induction of autoreactive B cells allows priming of autoreactive T cells
18. Modulation of signalling via the B cell antigen receptor by CD21, the receptor for C3dg and EBV
19. Intersection of the complement and immune systems: A signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19
20. Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes
21. Tolerance, danger, and the extended family
22. Role of C3 in humoral immunity: Deficient antibody production in C3-deficient dogs
23. Role of complement in induction of antibody production in vivo. Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses
24. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
25. Covalent binding of C3b to monoclonal antibodies selectively up-regulates heavy chain epitope recognition by T cells
26. Differential T cell co-stimulatory requirements in CD28-deficient mice
27. CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein-Barr virus-related cytoplasmic tail
28. Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily
29. Natural antibody and complement-mediated antigen processing and presentation by B lymphocytes
30. Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex
31. CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase
32. The CR2/CD19 complex on human B cells contain the src-family kinase Lyn
33. Suppressive effect of antibody on processing of T cell epitopes
34. Signalling through CD19 activates a Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/phosphatidylinositol 3-kinase complex in human B cell