Modification of Escherichia coli B glutathione synthetase with polyethylene glycol for clinical application to enzyme replacement therapy for glutathione deficiency

Clinical and Diagnostic Laboratory Immunology

Volumn 3, Issue 6, 1996, Pages 663-668

  Inoue, Yoshiharu ^a   Sugiyama, Kei Ichi ^a   Ueminami, Hiroya ^a   Izawa, Shingo ^a   Kimura, Akira ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; GLUTATHIONE SYNTHASE; MACROGOL;

ANAPHYLAXIS; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; ENZYME REPLACEMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THERMOSTABILITY;

EID: 0029979730     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/cdli.3.6.663-668.1996     Document Type: Article

References (17)

1. Barton, N. W., F. S. Furbish, G. J. Murray, M. Garfleld, and R. O. Brady. 1990. Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher disease. Proc. Natl. Acad. Sci. USA 87:1913-1916.
2. Berger, E. A., T. K. Fuerst, and B. Moss. 1988. A soluble recombinant polypeptide comprising the amino-tcrminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 85:2357-2361.
3. Beutler, E., R. Lisker, and W. Kuhl. 1990. Molecular biology of G6PD variants. Biomed. Biochim. Acta 49:5236-5241.
4. Bory, C., R. Boulieu, G. Souillet, C. Chantin, P. Guibaud, and M. S. Hershfield. 1991. Effect of polyethylene glycol-modified adenosine deaminase (PEG-ADA) therapy in two ADA-deficient children: measurement of erythrocyte deoxyadenosine triphosphate as a useful tool. Adv. Exp. Med. Biol. 309A:173-176.
5. Brosius, J., and A. Holy. 1984. Regulation of ribosomal RNA promoters with a synthetic lac operator. Proc. Natl. Acad. Sci. USA 81:6929-6933.
6. Gushima, H., S. Yasuda, E. Soeda, M. Yokota, and A. Kimura. 1984. Complete nucleotide sequence of the E. coli glutathione synthetase gshII. Nucleic Acids Res. 12:9299-9307.
7. Haber, E., T. Quertermous, G. R. Matsueda, and M. S. Runge. 1989. Innovative approaches to plasminogen activator therapy. Science 243:51-56.
8. Hershficld, M. S., S. Chaffee, L. Koro-Johnson, A. Mary, A. A. Smith, and S. A. Short. 1991. Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol. Proc. Natl. Acad. Sci. USA 88:7185-7189.
9. Hibi, T., H. Kato, T. Nishioka, J. Oda, H. Yamaguchi, Y. Katsube, K. Tanizawa, and T. Fukui. 1993. Use of adenosinc (5′)polyphospho(5′)pyridoxals to study the substrate-binding region of glutathione synthetase from Escherichia coli B. Biochemistry 32:1548-1554.
10. - radical. J. Am. Chem. Soc. 94:7950-7957.
11. Inoue, Y., T. Ichiryu, K. Yoshikawa, L.-T. Tran, K. Murata, and A. Kimura. 1990. Induction of glutathione peroxidase by linoleic acid hydroperoxide in Hansenula mrakii. Agric. Biol. Chem. 54:3289-3293.
12. Inoue, Y., and A. Kimura. 1995. Methylglyoxal and regulation of its metabolism in microorganisms. Adv. Microb. Physiol. 37:177-227.
13. Inoue, Y., L.-T. Tran, M. Kamakura, S. Izawa, T. Miki, Y. Tsujimoto, and A. Kimura. 1995. Oxidative stress response in yeast: glutathione peroxidase of Hansenula mrakii is bound to the membrane of both mitochondria and cytoplasm. Biochim. Biophys. Acta 1245:325-330.
14. Kato, H., T. Tanaka, T. Nishioka, A. Kimura, and J. Oda. 1988. Role of cysteine residues in glutathione synthetase from Escherichia coli B. Chemical modification and oligonucleotide site-directed mutagenesis. J. Biol. Chem. 263:11646-11651.
15. Katre, N. V. 1990. Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol. J. Immunol. 144:209-213.
16. Katre, N. V., M. J. Knauf, and W. J. Laird. 1987. Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl. Acad. Sci. USA 84:1487-1491.
17. Kimura, A. 1986. Application of recDNA techniques to production of ATP and glutathione by syntechno system. Adv. Biochem. Eng./Biotechnol. 33:29-51.