Characterization of a chicken monoclonal antibody that recognizes the apical complex of Eimeria acervulina sporozoites and partially inhibits sporozoite invasion of CD8+ T lymphocytes in vitro

Journal of Parasitology

Volumn 82, Issue 1, 1996, Pages 82-87

  Sasai, Kazumi ^a   Lillehoj, Hyun S ^a   Matsuda, Haruo ^a,b   Wergin, William P ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACERVULINA; CONOIDEA; EIMERIA; EIMERIA ACERVULINA; GALLUS GALLUS; ANIMALIA;

CD8 ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CHICKEN; DNA DETERMINATION; EIMERIA; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; MYELOMA; NONHUMAN; PARASITE IMMUNITY; PARASITOSIS; SPOROZOITE; SUPPRESSOR CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, PROTOZOAN; BLOTTING, WESTERN; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHICKENS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EIMERIA; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HYBRIDOMAS; MICROSCOPY, IMMUNOELECTRON; MOLECULAR WEIGHT; MULTIPLE MYELOMA; SPLEEN; TUMOR CELLS, CULTURED;

EID: 0029979547     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.2307/3284120     Document Type: Article

References (27)

1. AL-ATTAR, M. A., AND M. A. FERNANDO, 1987. Transport of Eimeria necatrix sporozoites in the chicken: Effects of injected injected intraperitoneally. Journal of Parasitology 73: 494-502.
2. CASTLE, M. D., M. C. JENKINS, H. D. DANFORTH, AND H. S. LILLEHOJ. 1991. Characterization of a recombinant Eimeria acervulina antigen expressed in sporozoite and merozoite developmental stages. Journal of Parasitology 77: 384-390.
3. DANFORTH, H. D. 1983. Use of monoclonal antibodies directed against Eimeria tenella sporozoites to determine stage specificity and in vitro effect on parasite penetration and development. American Journal of Veterinary Research 44: 1722-1727.
4. D'HAESE, J., H. MEHLHORN, AND W. PETER. 1977. Comparative study of pellicular structures in coccidia. International Journal for Parasitology 7: 505-518.
5. DUBREMETZ, J. F., AND J. D. SCHWARTMAN. 1993. Subcellular organelles of Toxoplasma gondii and host cell invasion. Research in Immunology 144: 31-33.
6. JENKINS, M. C., AND J. B. DAME. 1987. Identification of immunodominant surface antigens of Eimeria acervulina sporozoites and merozoites. Molecular and Biochemical Parasitology 25: 155-164.
7. JOINER, K. A., AND J. F. DUBREMETZ. 1993. Toxoplasma gondir. A protozoan for the nineties. Infection and Immunity 61: 1169-1172.
8. Ko, C., C. K. SMITH, AND M. McDONELL. 1990. Identification and characterization of a target antigen of a monoclonal antibody directed against Eimeria tenella merozoites. Molecular and Biochemical Parasitology 41: 53-64.
9. LAEMMLI, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277: 680-682.
10. LAWN, A. M., AND M. E. ROSE. 1982. Mucosal transport of Eimena tenella in the cecum of the chicken. Journal of Parasitology 68: 1117-1123.
11. LILLEHOJ, H. S., E. P. LILLEHOJ, D. WEINSTOCK, AND K. SCHAT. 1988. Functional and biochemical characterization of chicken T lymphocyte antigens. European Journal of Immunology 18: 2059-2065.
12. _, AND M. D. RUFF. 1986. Comparison of disease susceptibility and subclass-specific antibody response in SC and FP chickens experimentally inoculated with Eimeria tenella, E. acervulina, or E maxima. Avian Diseases 31: 112-119.
13. _, K. SASAI, AND H. MATSUDA. 1994. Development and characterization of chicken-chicken B cell hybridomas secreting monoclonal antibodies that detect sporozoite and merozoite antigens of Eimeria. Poultry Science 73: 1685-1693.
14. _, AND J. T. TROUT. 1993. Coccidia: A review of recent advances on immunity and vaccine development. Avian Pathology 22: 3-21.
15. _, AND _. 1994. CD8 T cell-coccidia interactions. Parasitology Today 10: 10-13.
16. NISHINAKA, S., T. SUZUKI, H. MATSUDA, AND M. MURATA. 1991. A new cell line for the production of chicken monoclonal antibody by hybridoma technology. Journal of Immunological Methods 139: 217-222.
17. PERKINS, M. E. 1992. Rhoptry organelles of apicomplexan parasites. Parasitology Today 8: 28-32.
18. ROSE, M. E., A. M. LAWN, AND B. J. MILLARD. 1984. The effect of immunity on the early events in the life-cycle of Eimeria tenella in the caecal mucosa of the chicken. Parasitology 88: 199-210.
19. RUSSELL, D. G., AND R. G. BURNS. 1984. The polar ring of coccidian sporozoites: A unique microtubule-organizing center. Journal of Cell Science 65: 193-207.
20. RYLEY, J. F., R. MEADE, J. HAZELHURST, AND T. E. ROBINSON. 1976. Methods in coccidiosis research: Separation of oocysts from faeces. Parasitology 73: 311-326.
21. SCHMATZ, D. M., S. J. CRANE, AND P. K. MURRAY. 1984. Purification of Eimeria sporozoites by DE-52 anion exchange chromatography. Journal of Protozoology 31: 181-183.
22. SCHWARTZMAN, J. D., AND L. D. SAFFER. 1992. How does Toxoplasma gondii gets in and out of host cells? Subcellular Biochemistry 18: 333-364.
23. SPEER, C. A., R. B. WONG, AND R. H. SCHENKEL. 1983. Ultrastructural localization of monoclonal IgG antibodies for antigenic sites of Eimeria tenella oocysts, sporocysts, and sporozoites. Journal of Protozoology 30: 548-554.
24. TOWBIN, H., T. STAEHELIN, AND J. GORDON. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proceedings of the National Academy of Sciences USA 79: 4350-4354.
25. + lymphocytes and macrophages in transport of Eimeria acervulina. Journal of Parasitology 73: 790-792.
26. UNI, S., A. MATSUDA, M. J. STEWART, I. IGARASHI, R. S. NUSSENZWEIG, AND M. AIKAWA. 1987. Ultrastructural localization of the 150/ 130 kd antigens in sexual and asexual blood stages of Plasmodium falciparum-infected human erythrocytes. American Journal of Tropical Medicine and Hygiene 36: 481-488.
27. WERK, R. 1985. How does Toxoplasma gondii enter host cells? Reviews of Infectious Diseases 7: 449-457.