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Volumn 24, Issue 5, 1996, Pages 560-564

Disposition of valpromide, valproic acid, and valnoctamide in the brain, liver, plasma, and urine of rats

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; PRODRUG; UNCLASSIFIED DRUG; VALNOCTAMIDE; VALNOCTIC ACID; VALPROIC ACID; VALPROIC ACID DERIVATIVE; VALPROMIDE;

EID: 0029979326     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (37)

References (39)
  • 1
    • 0026015881 scopus 로고
    • Clinical pharmacology of valpromide
    • M. Bialer Clinical pharmacology of valpromide. Clin. Pharmacokinet. 20, 114-122 (1991).
    • (1991) Clin. Pharmacokinet. , vol.20 , pp. 114-122
    • Bialer, M.1
  • 2
    • 0007859801 scopus 로고
    • A clinical study on the use of valmethamide as anxiety-reducing drug
    • W. Stephansky: A clinical study on the use of valmethamide as anxiety-reducing drug. Curr. Ther. Res. 2, 144-149 (1960).
    • (1960) Curr. Ther. Res. , vol.2 , pp. 144-149
    • Stephansky, W.1
  • 3
    • 0019130065 scopus 로고
    • Valnoctamide: Pharmacological data suggesting an antiepileptic activity
    • J. P. Chambon and A. Peiro: Valnoctamide: pharmacological data suggesting an antiepileptic activity. Neurosci. Lett. Suppl. S327-S327 (1980).
    • (1980) Neurosci. Lett. Suppl.
    • Chambon, J.P.1    Peiro, A.2
  • 4
    • 0024440860 scopus 로고
    • Structure-pharmacokinetic relationships in a series of valpromide derivatives with antiepileptic activity
    • A. Haj-Yehia and M. Bialer Structure-pharmacokinetic relationships in a series of valpromide derivatives with antiepileptic activity. Pharm. Res. 6, 682-689 (1989).
    • (1989) Pharm. Res. , vol.6 , pp. 682-689
    • Haj-Yehia, A.1    Bialer, M.2
  • 5
    • 0024266719 scopus 로고
    • Pharmacokinetics of a valpromide isomer, valnoctamide, in dogs
    • A. Haj-Yehia and M. Bialer: Pharmacokinetics of a valpromide isomer, valnoctamide, in dogs. J. Pharm. Sci. 77, 831-834 (1988).
    • (1988) J. Pharm. Sci. , vol.77 , pp. 831-834
    • Haj-Yehia, A.1    Bialer, M.2
  • 6
    • 0025090893 scopus 로고
    • Structure-pharmacokinetic relationships in a series of short chain fatty acid amides that possess anticonvulsant activity
    • A. Haj-Yehia and M. Bialer: Structure-pharmacokinetic relationships in a series of short chain fatty acid amides that possess anticonvulsant activity. J. Pharm. Sci. 79, 719-724 (1990).
    • (1990) J. Pharm. Sci. , vol.79 , pp. 719-724
    • Haj-Yehia, A.1    Bialer, M.2
  • 9
    • 0020604494 scopus 로고
    • A comparative study on the pharmacokinetics of valpromide after intravenous administration in dogs
    • M. Bialer and A. Rubinstein: A comparative study on the pharmacokinetics of valpromide after intravenous administration in dogs. J. Pharm. Pharmacol. 35, 607-609 (1983).
    • (1983) J. Pharm. Pharmacol. , vol.35 , pp. 607-609
    • Bialer, M.1    Rubinstein, A.2
  • 10
    • 0021260414 scopus 로고
    • Pharmacokinetics of valpromide in dogs after various modes of administration
    • M. Bialer and A. Rubinstein: Pharmacokinetics of valpromide in dogs after various modes of administration. Biopharm. Drug Dispos. 5, 177-183 (1984).
    • (1984) Biopharm. Drug Dispos. , vol.5 , pp. 177-183
    • Bialer, M.1    Rubinstein, A.2
  • 11
    • 0025248831 scopus 로고
    • The disposition of valpromide in rats and in the isolated perfused rat liver
    • H. Billig, E. Ziv, H. Bar-On, and M. Bialer: The disposition of valpromide in rats and in the isolated perfused rat liver. Drug Metab. Dispos. 18, 238-244 (1990).
    • (1990) Drug Metab. Dispos. , vol.18 , pp. 238-244
    • Billig, H.1    Ziv, E.2    Bar-On, H.3    Bialer, M.4
  • 12
    • 0022002801 scopus 로고
    • Pharmacological evaluation of various metabolites and analogues of valproic acid
    • W. Loscher and H. Nau: Pharmacological evaluation of various metabolites and analogues of valproic acid. Neuropharmacology 24, 427-435 (1985).
    • (1985) Neuropharmacology , vol.24 , pp. 427-435
    • Loscher, W.1    Nau, H.2
  • 13
    • 0026001902 scopus 로고
    • Valproic acid-induced neural tube defects in mouse and human: Aspects of chirality, alternative drug development, pharmacokinetics and possible mechanism
    • H. Nau, R.-S. Huck, and K. Eblers: Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanism. Pharmacol. Toxicol. 69, 310-321 (1991).
    • (1991) Pharmacol. Toxicol. , vol.69 , pp. 310-321
    • Nau, H.1    Huck, R.-S.2    Eblers, K.3
  • 14
    • 0021948924 scopus 로고
    • A comparative pharmacokinetic study of valpromide and valproic acid after intravenous administration in humans
    • M. Bialer, A. Rubinstein, J. Dubrovsky, I. Raz, and O Abramsky: A comparative pharmacokinetic study of valpromide and valproic acid after intravenous administration in humans. Int. J. Pharm. 23, 25-33 (1985).
    • (1985) Int. J. Pharm. , vol.23 , pp. 25-33
    • Bialer, M.1    Rubinstein, A.2    Dubrovsky, J.3    Raz, I.4    Abramsky, O.5
  • 15
    • 0026733527 scopus 로고
    • Pharmacokinetic analysis of the structural requirements for forming stable analogues of valpromide
    • A. Haj-Yehia, S. Hadad, and M. Bialer: Pharmacokinetic analysis of the structural requirements for forming stable analogues of valpromide. Pharm. Res. 9, 1058-1063 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 1058-1063
    • Haj-Yehia, A.1    Hadad, S.2    Bialer, M.3
  • 16
    • 0026269993 scopus 로고
    • The brain distribution of old and new antiepileptic drugs
    • F. Pisani, E. Perucca, G. Avanzini, and A. Richens, eds., Elsevier, Amsterdam
    • F. Monaco and G. Sechi: The brain distribution of old and new antiepileptic drugs. In "New Antiepileptic Drugs" (F. Pisani, E. Perucca, G. Avanzini, and A. Richens, eds.), pp. 57-65. Elsevier, Amsterdam, 1991.
    • (1991) New Antiepileptic Drugs , pp. 57-65
    • Monaco, F.1    Sechi, G.2
  • 17
    • 0025827397 scopus 로고
    • Comparison of valproate concentrations in human plasma, CSF and brain distribution after administration of different formulations of valproate and valpromide
    • H. G. Wieser: Comparison of valproate concentrations in human plasma, CSF and brain distribution after administration of different formulations of valproate and valpromide. Epilepsy Res. 9, 154-159 (1991).
    • (1991) Epilepsy Res. , vol.9 , pp. 154-159
    • Wieser, H.G.1
  • 18
    • 0028097892 scopus 로고
    • Disposition and protein binding of valproic acid in the developing rat
    • L. J. Haberer and G. M. Pollack: Disposition and protein binding of valproic acid in the developing rat. Drug Metab. Dispos. 22, 113-119 (1994).
    • (1994) Drug Metab. Dispos. , vol.22 , pp. 113-119
    • Haberer, L.J.1    Pollack, G.M.2
  • 19
    • 0021270970 scopus 로고
    • A rapid GLC assay for monitoring valproic acid and valpromide in plasma
    • M. Bialer, M. Friedman, and A. Rubinstein: A rapid GLC assay for monitoring valproic acid and valpromide in plasma. J. Pharm. Sci. 73, 991-993 (1984).
    • (1984) J. Pharm. Sci. , vol.73 , pp. 991-993
    • Bialer, M.1    Friedman, M.2    Rubinstein, A.3
  • 20
    • 0021957017 scopus 로고
    • Rapid gas chromatography assay for monitoring valnoctamide
    • M. Bialer and B. Hoch: Rapid gas chromatography assay for monitoring valnoctamide. J. Chromatogr. Biomed. Appl. 337, 408-411 (1985).
    • (1985) J. Chromatogr. Biomed. Appl. , vol.337 , pp. 408-411
    • Bialer, M.1    Hoch, B.2
  • 23
    • 0018606615 scopus 로고
    • Non-compartmental determination of steady-state volume of distribution
    • L. Z. Benet and R. L. Galeazzi: Non-compartmental determination of steady-state volume of distribution. J. Pharm. Sci. 68, 1071-1074 (1979).
    • (1979) J. Pharm. Sci. , vol.68 , pp. 1071-1074
    • Benet, L.Z.1    Galeazzi, R.L.2
  • 26
    • 0015731028 scopus 로고
    • Utilization of area under the curve to elucidate the disposition of extensively biotransformed drug
    • S. A. Kaplan, M. L. Jack, S. Cotler, and K. Alexander: Utilization of area under the curve to elucidate the disposition of extensively biotransformed drug. J. Pharmacokinet. Biopharm. 1, 201-216 (1973).
    • (1973) J. Pharmacokinet. Biopharm. , vol.1 , pp. 201-216
    • Kaplan, S.A.1    Jack, M.L.2    Cotler, S.3    Alexander, K.4
  • 27
    • 0016566218 scopus 로고
    • A physiological approach to hepatic clearance
    • G. R. Wilkinson and D. G. Shand: A physiological approach to hepatic clearance. Clin. Pharmacol. Ther. 18, 377-389 (1975).
    • (1975) Clin. Pharmacol. Ther. , vol.18 , pp. 377-389
    • Wilkinson, G.R.1    Shand, D.G.2
  • 29
    • 0010995132 scopus 로고
    • Federation of American Societies for Experimental Biology, Bethesda, MD
    • P. L. Altman and D. S. Dittmer: "Biological Data Book," 2nd ed., vol. 3, pp. 1702-1710. Federation of American Societies for Experimental Biology, Bethesda, MD, 1974.
    • (1974) "Biological Data Book," 2nd Ed. , vol.3 , pp. 1702-1710
    • Altman, P.L.1    Dittmer, D.S.2
  • 30
    • 0020065793 scopus 로고
    • Valproic acid: Brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse
    • H. Nau and W. Loscher: Valproic acid: brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse. J. Pharmacol. Exp. Ther. 220, 654-659 (1982).
    • (1982) J. Pharmacol. Exp. Ther. , vol.220 , pp. 654-659
    • Nau, H.1    Loscher, W.2
  • 32
    • 0020610769 scopus 로고
    • Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment
    • W. Loscher and H. Nau: Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment. J. Pharmacol. Exp. Ther. 226, 845-854 (1983).
    • (1983) J. Pharmacol. Exp. Ther. , vol.226 , pp. 845-854
    • Loscher, W.1    Nau, H.2
  • 33
    • 0022004486 scopus 로고
    • Physiologically based pharmacokinetics of valproic acid in rabbits
    • R. Ichimura, Y. Deguchi, K. Yokogama, and T. Yamana: Physiologically based pharmacokinetics of valproic acid in rabbits. Int. J. Pharm. 27, 45-60 (1985).
    • (1985) Int. J. Pharm. , vol.27 , pp. 45-60
    • Ichimura, R.1    Deguchi, Y.2    Yokogama, K.3    Yamana, T.4
  • 34
    • 0021999852 scopus 로고
    • Diurnal oscillations of CFS valproate in monkey
    • J. S. Lockard, C. T. Viswanthan, and R. H. Levy: Diurnal oscillations of CFS valproate in monkey. Life Sci. 36, 1281-1285 (1985).
    • (1985) Life Sci. , vol.36 , pp. 1281-1285
    • Lockard, J.S.1    Viswanthan, C.T.2    Levy, R.H.3
  • 35
    • 0025731391 scopus 로고
    • 2-valproate and valproate in rats
    • 2-valproate and valproate in rats. Epilepsia 32, 232-241 (1991).
    • (1991) Epilepsia , vol.32 , pp. 232-241
    • Semmes, R.L.O.1    Shen, D.D.2
  • 36
    • 0019469772 scopus 로고
    • Human brain plasma and cerebrospinal fluid concentration of sodium valproate after 72 hours of therapy
    • F. J. E. Vajda, G. A. Donnan, J. Phillips, and P. F. Bladin: Human brain plasma and cerebrospinal fluid concentration of sodium valproate after 72 hours of therapy. Neurology 31, 486-487 (1981).
    • (1981) Neurology , vol.31 , pp. 486-487
    • Vajda, F.J.E.1    Donnan, G.A.2    Phillips, J.3    Bladin, P.F.4
  • 37
    • 0023934905 scopus 로고
    • Penetration of valproate and its active metabolites into cerebrospinal fluid of children with epilepsy
    • W. Loscher, H. Nau, and H. Siemes: Penetration of valproate and its active metabolites into cerebrospinal fluid of children with epilepsy. Epilepsia 29, 311-316 (1988).
    • (1988) Epilepsia , vol.29 , pp. 311-316
    • Loscher, W.1    Nau, H.2    Siemes, H.3
  • 39
    • 0028299479 scopus 로고
    • Distribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system
    • K. D. K. Adkison, A. A. Arturu, K. M. Powers, and D. D. Shen: Distribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system. J. Pharmacol. Exp. Ther. 268, 797-805 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 797-805
    • Adkison, K.D.K.1    Arturu, A.A.2    Powers, K.M.3    Shen, D.D.4


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