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Volumn 270, Issue 4 39-4, 1996, Pages

Adipose-specific overexpression of GLUT-4 in transgenic mice alters lipoprotein lipase activity

Author keywords

fatty acids; hexose transporters; obesity; transgene

Indexed keywords

FATTY ACID; GLUCOSE TRANSPORTER; GLYCEROL; INSULIN; LIPOPROTEIN LIPASE; TRIACYLGLYCEROL;

EID: 0029979230     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.270.4.r785     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 1842340322 scopus 로고
    • Metabolism of fatty acids: An overview
    • edited by G. A. Bray, D. L. Ricquier, and B. M. Spiegelman. New York: Wiley-Liss
    • Arner, P. Metabolism of fatty acids: an overview. In: Obesity. Towards a Molecular Approach, edited by G. A. Bray, D. L. Ricquier, and B. M. Spiegelman. New York: Wiley-Liss, 1990, p. 159-172.
    • (1990) Obesity. Towards a Molecular Approach , pp. 159-172
    • Arner, P.1
  • 2
    • 0025997045 scopus 로고
    • Weight reduction increases adipose but decreases cardiac LPL in reduced-obese Zucker rats
    • Endocrinol. Metab. 24
    • Bessesen, D. H., A. D. Robertson, and R. H. Eckel. Weight reduction increases adipose but decreases cardiac LPL in reduced-obese Zucker rats. Am. J. Physiol. 261 (Endocrinol. Metab. 24): E246-E251, 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Bessesen, D.H.1    Robertson, A.D.2    Eckel, R.H.3
  • 3
    • 0002817434 scopus 로고
    • Heart and skeletal muscle lipoprotein lipase
    • edited by J Borensztajn. Chicago: Evener
    • Borensztajn, J. Heart and skeletal muscle lipoprotein lipase. In: Lipoprotein Lipase, edited by J Borensztajn. Chicago: Evener, 1987, p. 133-148.
    • (1987) Lipoprotein Lipase , pp. 133-148
    • Borensztajn, J.1
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 5
    • 0026660028 scopus 로고
    • Molecular and metabolic changes in white adipose tissue of the rat during development of ventromedial hypothalamic obesity
    • Cousin, B., K. Agou, A. Leturque, P. Ferre, J. Girard, and L. Penicaud. Molecular and metabolic changes in white adipose tissue of the rat during development of ventromedial hypothalamic obesity Eur. J. Biochem. 207: 377-382, 1992.
    • (1992) Eur. J. Biochem. , vol.207 , pp. 377-382
    • Cousin, B.1    Agou, K.2    Leturque, A.3    Ferre, P.4    Girard, J.5    Penicaud, L.6
  • 6
    • 0014830814 scopus 로고
    • Structure-function relationship in the adipose cell. I. Ultrastructure of the isolated adipose cell
    • Cushman, S. W. Structure-function relationship in the adipose cell. I. Ultrastructure of the isolated adipose cell. J. Cell Biol. 46: 326-341, 1970
    • (1970) J. Cell Biol. , vol.46 , pp. 326-341
    • Cushman, S.W.1
  • 7
    • 0017904216 scopus 로고
    • Determination of adipose cell size and number in suspensions of isolated rat and human adipose cells
    • Cushman, S. W., and L. Salans. Determination of adipose cell size and number in suspensions of isolated rat and human adipose cells. J. Lipid Res. 19: 269-273, 1978.
    • (1978) J. Lipid Res. , vol.19 , pp. 269-273
    • Cushman, S.W.1    Salans, L.2
  • 8
    • 0025264939 scopus 로고
    • The response to lipoprotein lipase to feeding and fasting: Evidence for posttranslational regulation
    • Doolittle, M. H., O. Ben-Zeev, J. Elovson, D. Martin, and T. G. Kirchgessner. The response to lipoprotein lipase to feeding and fasting: evidence for posttranslational regulation. J. Biol. Chem. 265: 4570-4577, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4570-4577
    • Doolittle, M.H.1    Ben-Zeev, O.2    Elovson, J.3    Martin, D.4    Kirchgessner, T.G.5
  • 9
    • 0002549713 scopus 로고
    • Adipose tissue lipoprotein lipase
    • edited by J. Borensztajn. Chicago: Evener
    • Eckel, R. H. Adipose tissue lipoprotein lipase. In: Lipoprotein Lipase, edited by J. Borensztajn. Chicago: Evener, 1987, p. 79-132.
    • (1987) Lipoprotein Lipase , pp. 79-132
    • Eckel, R.H.1
  • 10
    • 0024500560 scopus 로고
    • Lipoprotein lipase: A multifunctional enzyme relevant to common metabolic diseases
    • Eckel, R. H. Lipoprotein lipase: a multifunctional enzyme relevant to common metabolic diseases. N. Engl. J. Med. 320: 1060-1068, 1989.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1060-1068
    • Eckel, R.H.1
  • 11
    • 0008796412 scopus 로고
    • Methods for studying lipoprotein lipase in human adipose tissue
    • edited by F. L. Pohl, W. L. Clarke, and J. Lamer. Poughkeepsie, NY: Wiley
    • Eckel, R. H., P. A. Kern, C. N. Sadur, and T. J. Yost. Methods for studying lipoprotein lipase in human adipose tissue. In: Methods in Diabetes Research, edited by F. L. Pohl, W. L. Clarke, and J. Lamer. Poughkeepsie, NY: Wiley, 1986, p. 259-273.
    • (1986) Methods in Diabetes Research , pp. 259-273
    • Eckel, R.H.1    Kern, P.A.2    Sadur, C.N.3    Yost, T.J.4
  • 12
    • 0029037798 scopus 로고
    • Sustained weight reduction in moderately obese women results in decreased activity of skeletal muscle LPL
    • Eckel, R. H., T. J. Yost, and D. R. Jensen. Sustained weight reduction in moderately obese women results in decreased activity of skeletal muscle LPL. Eur. J. Clin. Invest. 25: 396-402, 1995.
    • (1995) Eur. J. Clin. Invest. , vol.25 , pp. 396-402
    • Eckel, R.H.1    Yost, T.J.2    Jensen, D.R.3
  • 13
    • 0028271599 scopus 로고
    • Macronutrient regulation of lipoprotein lipase is post translational
    • Erskine, J. M., D. R. Jensen, and R. H. Eckel. Macronutrient regulation of lipoprotein lipase is post translational. J. Nutrition 124: 500-507, 1994.
    • (1994) J. Nutrition , vol.124 , pp. 500-507
    • Erskine, J.M.1    Jensen, D.R.2    Eckel, R.H.3
  • 14
    • 0026032958 scopus 로고
    • Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans
    • Farese, R. V., Jr., T. J. Yost, and R. H. Eckel. Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans. Metabolism 40: 214-216, 1991.
    • (1991) Metabolism , vol.40 , pp. 214-216
    • Farese Jr., R.V.1    Yost, T.J.2    Eckel, R.H.3
  • 15
    • 0026563612 scopus 로고
    • Glucose transport in NIDDM
    • Garvey, W. T. Glucose transport in NIDDM. Diabetes Care 15: 396-417, 1992.
    • (1992) Diabetes Care , vol.15 , pp. 396-417
    • Garvey, W.T.1
  • 16
    • 15844368545 scopus 로고
    • Altered regulation of lipoprotein lipase activity in adipose tissue and muscle of transgenic mice overexpressing GLUT-4 selectivity in fat
    • 15a. Gnudi, L., D. R. Jensen, E. Tozzo, J. L. Bliss, R. H. Eckel, and B. B. Kahn. Altered regulation of lipoprotein lipase activity in adipose tissue and muscle of transgenic mice overexpressing GLUT-4 selectivity in fat. Diabetes 43, Suppl. 1: 133A, 1994.
    • (1994) Diabetes , vol.43 , Issue.1 SUPPL.
    • Gnudi, L.1    Jensen, D.R.2    Tozzo, E.3    Bliss, J.L.4    Eckel, R.H.5    Kahn, B.B.6
  • 17
    • 0028855754 scopus 로고
    • High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance
    • Gnudi, L., E. Tozzo, P. R. Shepherd, J. L. Bliss, and B. B. Kahn. High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance. Endocrinology 136: 995-1002, 1995.
    • (1995) Endocrinology , vol.136 , pp. 995-1002
    • Gnudi, L.1    Tozzo, E.2    Shepherd, P.R.3    Bliss, J.L.4    Kahn, B.B.5
  • 18
    • 0021721717 scopus 로고
    • Enzymatic alterations in the obese: Long or short-term regulatory errors?
    • Greenwood, M. Enzymatic alterations in the obese: long or short-term regulatory errors? Int. J. Obes. 8: 561-569, 1984.
    • (1984) Int. J. Obes. , vol.8 , pp. 561-569
    • Greenwood, M.1
  • 19
    • 0022382625 scopus 로고
    • The relationship of enzyme activity to feeding behavior in rats: Lipoprotein lipase as the metabolic gatekeeper
    • Greenwood, M. The relationship of enzyme activity to feeding behavior in rats: lipoprotein lipase as the metabolic gatekeeper. Int. J. Obes. Suppl. 1, 9: 67-70, 1985.
    • (1985) Int. J. Obes. Suppl. 1 , vol.9 , pp. 67-70
    • Greenwood, M.1
  • 20
    • 0014239615 scopus 로고
    • Methods for determination of adipose cell size in man and animals
    • Hirsch, J., and E. Gallian. Methods for determination of adipose cell size in man and animals. J. Lipid Res. 9: 110-119, 1968.
    • (1968) J. Lipid Res. , vol.9 , pp. 110-119
    • Hirsch, J.1    Gallian, E.2
  • 21
    • 0026624835 scopus 로고
    • Facilitative glucose transporters: Regulatory mechanisms and dysregulation in diabetes
    • Kahn, B. B. Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. J. Clin. Invest. 89: 1367-1374, 1992.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1367-1374
    • Kahn, B.B.1
  • 22
    • 0020576117 scopus 로고
    • In vitro insulin resistance of human adipocytes isolated from subjects with non insulin dependent diabetes mellitus
    • Kashiwagi, A., M. Antonio-Verso, J. Andrews, B. Vasquez, G. Reaven, and J. E. Foley. In vitro insulin resistance of human adipocytes isolated from subjects with non insulin dependent diabetes mellitus. J. Clin. Invest. 72:1246-1254, 1983.
    • (1983) J. Clin. Invest. , vol.72 , pp. 1246-1254
    • Kashiwagi, A.1    Antonio-Verso, M.2    Andrews, J.3    Vasquez, B.4    Reaven, G.5    Foley, J.E.6
  • 23
    • 0023634808 scopus 로고
    • Regulation of lipoprotein lipase by glucose in primary cultures of isolated human adipocytes: Relevance to the hypertriglyceridemia of diabetes
    • Kern, P. A., A. Mandic, and R. H. Eckel. Regulation of lipoprotein lipase by glucose in primary cultures of isolated human adipocytes: relevance to the hypertriglyceridemia of diabetes. Diabetes 36: 1238-1245, 1987.
    • (1987) Diabetes , vol.36 , pp. 1238-1245
    • Kern, P.A.1    Mandic, A.2    Eckel, R.H.3
  • 24
    • 0024420438 scopus 로고
    • Effects of insulin and exercise on muscle lipoprotein lipase activity in man and its relation to insulin action
    • Kiens, B., H. Lithell, K. J. Mikines, E. A. Richter. Effects of insulin and exercise on muscle lipoprotein lipase activity in man and its relation to insulin action. J. Clin. Invest. 84: 1124-1129, 1989.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1124-1129
    • Kiens, B.1    Lithell, H.2    Mikines, K.J.3    Richter, E.A.4
  • 25
    • 0028115762 scopus 로고
    • Long-chain fatty acids decrease lipoprotein lipase activity of cultured rat adipocyte precursors
    • Kirkland, J. L., C. H. Hollenberg, S. Kindler, and D. A. Roncari. Long-chain fatty acids decrease lipoprotein lipase activity of cultured rat adipocyte precursors. Metabolism 43: 144-151, 1994.
    • (1994) Metabolism , vol.43 , pp. 144-151
    • Kirkland, J.L.1    Hollenberg, C.H.2    Kindler, S.3    Roncari, D.A.4
  • 26
    • 0027394618 scopus 로고
    • Lipoprotein lipase synthesis and secretion: Effects of concentration and type of fatty acids in adipocyte cell culture
    • Montalto, M. B., and A. Bensadoun. Lipoprotein lipase synthesis and secretion: effects of concentration and type of fatty acids in adipocyte cell culture. J. Lipid Res. 34: 397-407, 1993.
    • (1993) J. Lipid Res. , vol.34 , pp. 397-407
    • Montalto, M.B.1    Bensadoun, A.2
  • 27
    • 0026000681 scopus 로고
    • High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (GLUT-4) in fat cells of rats
    • Pedersen, O., C. R. Kahn, J. S. Flier, and B. B. Kahn. High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (GLUT-4) in fat cells of rats. Endocrinology 129: 771-777, 1991.
    • (1991) Endocrinology , vol.129 , pp. 771-777
    • Pedersen, O.1    Kahn, C.R.2    Flier, J.S.3    Kahn, B.B.4
  • 28
    • 0026681195 scopus 로고
    • Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats
    • Pedersen, O., C. R. Kahn, and B. B. Kahn. Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats. J. Clin. Invest. 89: 1964-1973, 1992.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1964-1973
    • Pedersen, O.1    Kahn, C.R.2    Kahn, B.B.3
  • 29
    • 78651166782 scopus 로고
    • Metabolism of isolated fat cells. Effects of hormones on glucose metabolism and lipolysis
    • Rodbell, M. Metabolism of isolated fat cells. Effects of hormones on glucose metabolism and lipolysis. J. Biol. Chem. 239: 375-380, 1964.
    • (1964) J. Biol. Chem. , vol.239 , pp. 375-380
    • Rodbell, M.1
  • 31
    • 0020036933 scopus 로고
    • Insulin stimulation of adipose tissue lipoprotein lipase: Use of the euglycemic clamp technique
    • Sadur, C. N., and R. H. Eckel. Insulin stimulation of adipose tissue lipoprotein lipase: use of the euglycemic clamp technique J. Clin. Invest. 69: 1119-1125, 1982.
    • (1982) J. Clin. Invest. , vol.69 , pp. 1119-1125
    • Sadur, C.N.1    Eckel, R.H.2
  • 32
    • 0022345789 scopus 로고
    • Effect of dietary fat content on the incidence of obesity among ad libitum fed mice
    • Salmon, D. M. V, and J. P. Flatt. Effect of dietary fat content on the incidence of obesity among ad libitum fed mice. Int. J. Obesity 9: 443-449, 1985.
    • (1985) Int. J. Obesity , vol.9 , pp. 443-449
    • Salmon, D.M.V.1    Flatt, J.P.2
  • 34
    • 0024593478 scopus 로고
    • Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids
    • Saxema, U., L. D. Witte, and I. J. Goldberg. Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids. J. Biol. Chem. 264: 4349-4355, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 4349-4355
    • Saxema, U.1    Witte, L.D.2    Goldberg, I.J.3
  • 35
    • 0019424849 scopus 로고
    • Increase of adipose tissue lipoprotein lipase activity after weight loss
    • Schwartz, R. S., and J. D. Brunzell. Increase of adipose tissue lipoprotein lipase activity after weight loss. J. Clin Invest. 67: 1425-1430, 1981.
    • (1981) J. Clin Invest. , vol.67 , pp. 1425-1430
    • Schwartz, R.S.1    Brunzell, J.D.2
  • 36
    • 0027453501 scopus 로고
    • Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT-4 selectively in adipose tissue
    • Shepherd, P. R., L. Gnudi, E. Tozzo, H. Yang, F. Leach, and B. B. Kahn. Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT-4 selectively in adipose tissue. J. Biol. Chem. 268: 22243-22246, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22243-22246
    • Shepherd, P.R.1    Gnudi, L.2    Tozzo, E.3    Yang, H.4    Leach, F.5    Kahn, B.B.6
  • 37
    • 0019510376 scopus 로고
    • Lipoprotein lipase of adipose tissue and skeletal muscle in human obesity: Response to glucose and to semistarvation
    • Taskinen, M. R., and E. A. Nikkila. Lipoprotein lipase of adipose tissue and skeletal muscle in human obesity: response to glucose and to semistarvation. Metabolism 30: 810-817, 1981.
    • (1981) Metabolism , vol.30 , pp. 810-817
    • Taskinen, M.R.1    Nikkila, E.A.2
  • 38
    • 0029034619 scopus 로고
    • Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: Preferential effect of fatty acid synthesis
    • Endocrinol. Metab. 31
    • Tozzo, E., P. R. Shepherd, L. Gnudi, and B. B. Kahn. Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect of fatty acid synthesis. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E956-E964, 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Tozzo, E.1    Shepherd, P.R.2    Gnudi, L.3    Kahn, B.B.4
  • 39
    • 0028263609 scopus 로고
    • Intracerebroventricular administration of neuropeptide Y to normal rats has divergent effects on glucose utilization by adipose tissue and skeletal muscle
    • Zarjevski, N., I. Cusin, R. Vettor, F. Rohner-Jeanrenaud, and B. Jeanrenaud. Intracerebroventricular administration of neuropeptide Y to normal rats has divergent effects on glucose utilization by adipose tissue and skeletal muscle. Diabetes 43: 764-769, 1994.
    • (1994) Diabetes , vol.43 , pp. 764-769
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5


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