Endogenous ecotropic and recombinant MCF mouse retro viral variation and escape from antiviral CTL

Seminars in Virology

Volumn 7, Issue 1, 1996, Pages 49-60

  Green, William R ^a   Smith, Patrick M ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Cytolytic T lymphocytes; Murine leukemia viruses; Viral escape

Indexed keywords

ENVELOPE PROTEIN; EPITOPE; VIRUS ANTIGEN;

ANIMAL MODEL; ANTIGEN RECOGNITION; ANTIGENIC VARIATION; CELLULAR IMMUNITY; CYTOTOXIC T LYMPHOCYTE; ECOTROPIC VIRUS; GENETIC RECOMBINATION; MURINE LEUKEMIA VIRUS; NONHUMAN; POINT MUTATION; PROTEIN VARIANT; RETROVIRUS; REVIEW; STRUCTURE ACTIVITY RELATION; VIRUS IMMUNITY; VIRUS RECOMBINANT;

EID: 0029978871     PISSN: 10445773     EISSN: None     Source Type: Journal    
DOI: 10.1006/smvy.1996.0007     Document Type: Article

References (76)

1. Cloyd MW, Thompson MM, Hartley JW (1985) Host range of mink cell focus-inducing viruses. Virol 140:239-248
2. Fischinger PJ, Nomura S, Bolognesi DP (1975) A novel murine oncornavirus with dual eco- and xenotropic properties. Proc Natl Acad Sci 72:5150-5155
3. Elder JH, Gautsch JW, Jensen FC, Lerner RA, Hartley JW, Rowe WP (1977) Biochemical evidence that MCF murine leukemia viruses are envelope (env) gene recombinants. Proc Natl Acad Sci 74:4676-4680
4. Chattopadhyay SK, Lander MR, Gupta S, Rands E, Lowy DR (1981) Origin of mink cytopathic focus-forming (MCF) viruses: Comparison with ecotropic and xenotropic murine leukemia virus genomes. Virol 113:4654-83
5. Gross L (1951) 'Spontaneous' leukemia developing in C3H mice following inoculation in infancy with AK leukemic extracts, or AK embryos. Proc Soc Exp Biol Med 76:27-32
6. Lilly F( 1966) The histocompatibility-2 locus and susceptibility to tumor induction. Natl Cancer Inst Monogr 22:631-636
7. Green WR (1984) Genetic control of the induction of cytolytic T lymphocyte responses to AKR/Gross viral leukemias. I. H-2-encoded dominant gene control. J Immunol 132:2658-2664
8. Townsend A, Bodmer H (1989) Antigen recognition by class I-restricted T lymphocytes. Annu Rev Immunol 7:601-624
9. Deverson E, Gow IR, Coadwell WJ, Monaco JJ, Butcher JC, Howard JC (1990) MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature (Lond) 348:738-741
10. Spies T, Bresnahan M, Bahram S, Arnold D, Blanck G, Mellins E, Pious D, DeMars R (1990) A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature (Lond) 348:744-747
11. Monaco JJ, Cho S, Attaya M (1990) Transport protein genes in the murine MHC: possible implications for antigen processing. Science (Wash DC) 250:1723-1726
12. Schmid DS, Rouse BT (1992) The role of T cell immunity in control of herpes simplex virus. Curr Top Micro Immunol 179:57-74
13. Chesebro B, Miyazawa M, Britt WJ (1990) Host genetic control of spontaneous and induced immunity to Friend murine retrovirus infection. Annu Rev Immunol 8:477-499
14. Fan H (1994) Retroviruses and their role in cancer, in The Retroviridae, Vol. 3 (Levy JA, ed.). Plenum Press, New York
15. Green WR, Nowinski RC, Henney CS (1979) The generation and specificity of cytotoxic T cells raised against syngeneic tumour cells bearing AKR/ Gross murine leukemia virus antigens. J Exp Med 150:51-66
16. Green WR (1980) H-2-restricted cytolytic T lymphocytes specific for a subclass of AKR endogenous leukemia virus-induced tumours: Correlation of tumour cell susceptibility with expression of the Gross cell surface antigen. J Immunol 125:2584-2590
17. Green WR, Nowinski RC, Henney CS (1980) Specificity of cytolytic T cells directed against AKR/Gross virus-induced syngeneic leukemias: Antibodies directed against H-2K, but not against viral proteins, inhibit lysis. J Immunol 125:647-655
18. Lowy DR, Rands E, Chattopadhyay SK, Garon CF, Hager GL (1980) Molecular cloning of infectious integrated murine leukemia virus DNA from infected mouse cells. Proc Natl Acad Sci USA 77:614-618
19. White HD, Robbins MD, Green WR (1990) Mechanism of escape of endogenous murine leukemia virus EMV-14 from recognition by anti-AKR/ Gross MuLV cytotoxic T lymphocytes. J Virol 64:2608-2619
20. Plata F, Lilly F (1979) Viral specificity of H-2 restricted T killer cells directed against syngeneic tumours induced by Gross, Friend, or Rauscher leukemia viruses. J Exp Med 150:1174-1186
21. Plata F, Kalil J, Zilber M-T, Fellous M, Levy D (1993) Identification of a viral antigen recognized by H-2-restricted cytolytic T lymphocytes on a murine leukemia virus-induced tumour. J Immunol 131:2551-2556
22. Plata F, Langlade-Demoyen P, Abastado J-P, Berbar T, Kourilsky P (1986) Molecular definition of retrovirus-induced antigens recognized by tumour-specific H-2-restricted cytolytic T lymphocytes. J Immunogen 13:263-268
23. Plata F, Langlade-Demoyen P, Abastado J-P, Berbar T, Kourilsky P (1987) Retrovirus antigens recognized by cytolytic T lymphocytes activate tumour rejection in vivo. Cell 48:232-240
24. Ramanathapuram M, Graziano RF, Green WR (1986) The specificity of H-2-restricted cytotoxic T lymphocytes directed to AKR/Gross leukemia virus-induced tumours. III. Coordinate alterations in viral gp70 antigen expression and restoration of CTL-suseeptibility to insusceptible variant tumours. J Immunol 136:2271-2279
25. Sijts AJAM, Ossendorp F, Mengede EAM, van den Elsen PJ, Melief CJM (1994) Immunodominant mink cell focus-inducing murine leukemia virus (MuLV)-encoded CTL epitope identified by its MHC class I-binding motif, explains MuLV-type-specificity of MCF-directed cytotoxic T lymphocytes. J Immunol 152:106-116
26. b-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR 623 that restores susceptibility of a tumour line to anti-AKR/ Gross MuLV cytotoxic T lymphocytes. J Virol 68:897-904
27. Falk K, Rotzschcke O, Stevanovic S, Jung G, Rammensee H-G (1991) Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature (Lond) 351:290-296
28. Herr W (1984) Nucleotide sequence of AKV murine leukemia virus. J Virol 49:471-478
29. b mice. Virol 202:500-505
30. b-restricted epitopes encoded by the endogenous ecotropic murine leukemia virus AKR623 that are recognized by anti-AKR/ Gross MuLV CTL. Viral Immunol 7:51-59
31. Green WR (1983) The specificity of H-2-restricted cytotoxic T lymphocytes directed to AKR/ Gross leukemia virus-induced tumours. I. Isolation of a selectively resistant variant tumour subclone. Eur J Immunol 13:863-870
32. Green WR, Brown MA (1983) The specificity of H-2-restricted cytotoxic T lymphocytes directed to AKR/ Gross leukemia virus-induced tumours. II. Altered gp70 display and production of noninfectious virus particles by an insusceptible variant tumour. Eur J Immunol 13:871-877
33. b mice. Cell Immunol 116:123-134
34. Green WR (1984) Genetic control of the induction of cytolytic T lymphocyte responses to AKR/Gross viral leukemias. J Immunol 132:2665-2671
35. b congenic mice: Age-dependent conversion to nonresponder phenotype. J Immunol 138:1602-1606
36. Coppola MA*, Lam TM*, Strawbridge RR, Green WR (1995) Recognition of endogenous ecotropic murine leukaemia viruses by anti-AKR/ Gross virus cytotoxic T lymphocytes (CTL): epitope variation in a CTL-resistant virus. J Gen Virol 76:635-641 (* Equal author contribution.)
37. Chattopadhyay SK, Morse III HC, Makino M, Ruscetti SK, Hartley JW (1991) Characteristics and contributions of defective, ecotropic, and mink cell focus-inducing viruses involved in a retrovirus induced immunodeficiency syndrome of mice. J Virol 65:4232-4241
38. Evavold BD, Sloan-Lancaster J, Allen PM (1993) Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol Today 14:602-609
39. b. Science 257:919-927
40. b molecule. Nature 348:213-216
41. Neisig A, Roelse J, Sijts AJAM, Ossendorp F, Feltkamp MCW, Kast WM, Melief CJM, Neefjes JJ (1995) Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. J Immunol 154:1273-1279
42. + CTL. J Immunol 154:6140-6156
43. Rammensee H-G, Falk K, Rotzschke O (1993) Peptides naturally presented by MHC class I molecules. Annu Rev Immunol 11:213-244
44. Matsumura M, Fremont DH, Peterson PA, Wilson IA (1992) Emerging principles of the recognition of peptide antigens by MHC class I molecules. Science 257:927-934
45. + cytotoxic T cells. J Virol 67:4086-4092
46. Laterjet R, Duplan J-F (1962) Experiment and discussion on leukaemogenesis by cell-free extracts of radiation-induced leukaemia in mice. Int J Radiat Biol 5:339-344
47. Mosier DE, Yetter RA, Morse III HC (1985) Retroviral induction of acute lymphoproliferative disease and profound immunosuppression in adult C57BL/6 mice. J Exp Med 161:766-784
48. Pattengale PK, Taylor CR, Twomey P, Hill S, Jonasson J, Beardsley T, Haas M (1982) Immunopathology of B cell lymphomas induced in C57BL/ 6 mice by dualtropic murine leukemia virus (MuLV). Am J Pathol 107:362-377
49. Jenkins NA, Copeland NG, Taylor BA, Lee BK (1982) Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA in chromosomes of Mus musculus. J Virol 43:26-36
50. Aziz DC, Hanna Z, Jolicoeur P (1989) Severe immunodeficiency disease induced by a defective murine leukaemia virus. Nature 338:505-508
51. Chattopadhyay SK, Morse III HC, Makino M, Ruscetti SK, Hartly JW (1989) Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome. Proc Natl Acad Sci USA 86:3862-3866
52. Huang M, Simard C, Jolicoeur P (1989) Immunodeficiency and clonal growth of target cells induced by helper-free defective retrovirus. Nature 246:1614-1617
53. Hartley JW, Fredrickson TN, Yetter RA, Makino M, Morse III HC (1989) Retrovirus-induced murine acquired immunodeficiency syndrome: natural history of infection and differing susceptibility of inbred mouse strains. J Virol 63:1223-1231
54. Schwarz DA, Green WR (1994) CTL responses to the gag polyprotein encoded by the murine AIDS defective retrovirus are strain dependent. J Immunol 153:4364-41
55. Green WR, Graziano RF (1986) Cytolytic T lymphocyte-defined retroviral antigens on normal cells: encoding by the Akv-1 proviral locus. Immunogen 23:106-110
56. Steffen DL, Raylor BA, Weinberg RA (1982) Continuing germ line integration of Akv pro viruses during the breeding of AKR mice and derivative recombinant inbred strains. J Virol 42:165-175
57. White HD, Green WR, Gine NR (1993) Molecular cloning of infectious ecotropic murine leukemia virus AK7 from an emv-14-positive AKXL-5 mouse and the resistance of AK7 to recognition by cytotoxic T lymphocytes. J Virol 67:5045-5050
58. Del Val M, Schlicht H, Ruppert T, Reddehase MJ, Koszinowski UH (1991) Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein. Cell 66:1145-1153
59. Chimini G, Pala P, Sire J, Jordan BR, Maryanski JL (1989) Recognition of oligonucleotide-encoded T cell epitopes introduced into a gene unrelated to the original antigen. J Exp Med 169:297-302
60. Hahn YS, Braciale VL, Braciale TL (1991) Presentation of viral antigen to class I major histocompatibility complex-restricted cytotoxic T lymphocyte. Recognition of an immunodominant influenza hemagglutinin site by cytotoxic T lymphocyte is independent of the position of the site in the hemagglutinin translation product. J Exp Med 174:733-736
61. Eisenlohr LC, Yewdell JW, Bennink JR (1992) Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes. J Exp Med 175:481-487
62. Momburg F, Roelse FJ, Hammerling GJ, Neefjes JJ (1994) Peptide size selection by the major histocompatibility complex-encoded peptide transporter. J Exp Med 179:1613-1623
63. k gene products in AKR leukemia. Immunogen 16:257-264
64. k gene product(s) from an AKR spontaneous leukemia. Immunogen 8:311-318
65. Festenstein H, Schmidt W (1981) Variation in MHC antigenic profiles of tumour cells and its biological effects. Immunol Rev 60:85-127
66. Green WR, Phillips JD (1986) Differential induction of H-2K vs H-2D class I major histocompatibility complex antigen expression by murine recombinant interferon-γ. J Immunol 137:814-818
67. Green WR, Rich RF, Beadling C (1988) Differential induction of H-2K versus H-2D class I major histocompatibility antigens by recombinant γ Interferon. J Exp Med 167:1616-1624
68. Rich RF, Gaffney KJ, White HD, Green WR (1990) Differential up-regulation of H-2D versus H-2K class I major histocompatibility expression by interferon-γ evidence against a trans-acting allele-specific factor. J Interferon Res 10:505-514
69. Schwarz DA, Buhlmann JE, Kuhne MR, Lam TM, White HD, Green WR (1993) Novel regulation of an MHC class I gene response to interferon-γ. Cell Immunol 150:90-100
70. b mouse strains. Cell Immunol 113:308-319
71. Green WR, Rich RF (1988) Genetic control of CTL responses to AKR/Gross virus: effect of inheritance of Akv proviruses. Immunogen 27:304-312
72. b and C57BL/ 6 mouse strains. J Immunol 149:1593-1598
73. b mice. An analysis of precursor cytotoxic T lymphocyte frequencies in young versus moderately aged mice. J Immunol 146:2469-2477
74. b mice. J Immunol 148:2961-2967
75. b congenic mice for anti-AKR/Gross MuLV CTL responses: Involvement of inhibitory cells as defined by adoptive transfer experiments. Cell Immunol 160:139-151
76. b lymphocytes inhibit the secondary in-vitro CTL response of primed responder cells to AKR/Gross MuLV-induced tumor cell stimulation. J Virol, in press.