Atopic dermatitis: Immunopathology and therapeutic implications

Journal of the Bahrain Medical Society

Volumn 8, Issue 1, 1996, Pages 43-51

  Ehlayel, Mohammad S ^a  

^a Louisiana State University Medical Centre   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ALPHA 1 ANTITRYPSIN; ALPHA INTERFERON; ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; CORTICOSTEROID; CROMOGLYCATE DISODIUM; CYCLOSPORIN A; IMMUNOGLOBULIN; METHOXSALEN; PAPAVERINE; PHOSPHODIESTERASE INHIBITOR; PLANT EXTRACT; PRIMROSE OIL; RECOMBINANT INTERLEUKIN 2; THYMOSTIMULIN;

ATOPIC DERMATITIS; CLINICAL FEATURE; DIET; HUMAN; IMMUNOPATHOLOGY; PHOTOTHERAPY; REVIEW;

EID: 0029978669     PISSN: 10156321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (78)

1. Hanifin JM. Atopic dermatitis, J AM Acad Dermatol 1982;6:1-13.
2. Hanifin JM. Atopic dermatitis in infants and children. Pediatr Dermatol 1991;38:763-89.
3. Hannifin JM, Schnider L, Leung Y et al Recombinant y-interferon therapy for atopic dermatitis, J AM Acad Dermatol 1993;28:189-97.
4. Moshell A. Atopic dermatitis: recent trends in apthogenesis and therapy J Invest Dermatol 1994;102:128-137.
5. Saarienen UM, Transfer of latent atopy by bone marrow transplantation. A case report J. Allergy Clin Immunol 1984;74:196-200.
6. Agosti JN+M, Sprenger JD, Lum LG, et al. Transfer of allergen-specific IgE mediated hypersensitivity with allogenic bone marrow transplantation. N Eng J Med 1988;319:1623-28.
7. Johnson E, Irons JS, Patterson R. et al. Serum IgE concentration in atopic dermatitis J allergy Clin Immunol 1974;54:94-9.
8. Jones HE, Inoyye JC, McGreity JL, et al. Atopic disease and serum IgE Br. J Dermatol 1975;92:17-25.
9. Horan RF, Schneider LC, Sheffer AL Allergic disorders and mastocytosis JAMA 1992;268:2858-68.
10. Lever R, Turbitt M, Sanderson A, Mackie R. Immunophenotyping of the cutaneous infiltrating and mononuclear cells in the peripheral blood of patients with atopic dermatitis J Invest Dermatol 1987;89:4-7.
11. Bernstein JA, Lawrence ID. The mast cell, a comprehensive, updated review Allergy Proc 1990; 11: 209-23.
12. Elliot ST, Hanifin JM. Delayed cutaneous hypersensitivity and lymphocyte transformation, dissociation in atopic dermatitis. Arch Dermatol 1979;115:36-9.
13. Geha RS, Reiherz E. Leung D, et al. Deficiency of suppressor T-cells in the hyper-IgE syndrome J Clini Invest 1981;68:783-91.
14. Hanifin JM, Cooper KD, Roth HL. Atopy and atopic drmatitis J Am Acad Dermatal 1986;15:703-6.
15. Rees J, Friedmann PS, Mathews INS. Contact sensitivity to dinitrochlorobenzene is impaired in atopic dermatitis subjects. Arch Dermatol 1990;126:1173-5.
16. Griffith CE, Voorhees J, Nikoloff BJ. Characterization of intercellular adhesion molecule 1 and HLA-DR expression in normal and infiltrated skin. Modulation by recombinant y-interferon and tumour necrosis factor. J Am Acad Dermatol 1989;18:617-29.
17. Groves RW, Ross E, Barker JN, et al . Effect of in vivo IL-1 on adhes molecule expression in normal human skin. J Invest Dermatol 1992;98:384-7.
18. Thornhill HM, Haskard DO,IL-4 regulates endothelial cell activation by IL-1 TNF, or y-IFN. J Immunol 1990;145:865-72.
19. Cooper KD, Gonzales-Ramos A, Mueier T, et al. Distinction of dermal Langerhans cells from dermal macrophages by triple colour flow cytometiric analysis of CD1a, CD1c, CD11, CD11b, FcIgGRII and HLA-DR. J Invest Dermatol 1992;98:596.
20. Cooper KD, Neises GR,Katz SI. Antigen-presenting OKM5+ melanophages appear in human epidermis after UVR: J Inves Dermatol 1986;86:363-70.
21. Taylor RS. Baadsgaard O, Hammerberg et al. Hyperstimulatory CD1a+ CD1b+ CD36+ Langerhans cells are responsible for increased autologous T lymphocyte reactivity to lesional epidermal cells of patients with atopic dermatitis J Immunol 1991;147:3794-3802.
22. Taylor RS, Hammerberg C, Chang L, et al. Mechanism of epidermal immunoreactivity in atopic dermatitis J Invest Dermatol 1990:94:584.
23. Zachary CB, Poulter LW, MacDonald DM. Cell-mediated immunity responses in atopic dermatitis. The relevance of antigen-presenting cells. Br J Dermatol 1985;28:810-6.
24. Jakob T, Huspith BN, Latchman YE, et al. Depressed lymphocyte transformation and the role of prostaglandins in atopic dermatitis. Clin Exp Immunol 1990;79:380-4.
25. Jujo K, Renz H, Abe J, et al Decreased y-interferon and increased IL-4 production in atopic dermatitis promotes IgE synthesis J Allergy Clin Immunol 1992;90:323-31.
26. Phipps RP, Stein SH, Roper RL. A new role of prostaglandin E regulation of the immune response .Immunology Today 1991;12:349-52.
27. Bos JD, Wierenga EA, Smitt JS, et al. Immune dysregulation in atopic dermatitis. Arch Dermatol 1992;128:1509-12.
28. Van der Heidjen FL, Wierenga EA, Bos JD, et al. High frequency of IL-4 producing CD4+ allergen-specific T lymphocyte in atopic dermatitis J Invest Dermatol 1997;384-389.
29. Ramb-Lindhauer C, Feldman A. Rotte M, et al. Characterization of grass pollen reactive T-cells line derived from lesional atopic skin. Arch Dermatol Res 1991;283:71-76.
30. Broberg A, Kalimo K, Lindblad B, et al. Parental education in the treatment of childhood atopic eczema. Acta Dermatol Venereol (Stock) 1990;70: 495-9.
31. Sampson HA,. The immunopatholgenetic role of food hypersensitivity in atopic dermatitis. Acta Dermatol Venereol (Stockh) 1992;176:S34-7.
32. Nicol NH. Current considerations and management of atopic dermatitis, Dermatol Nurs 1990;2:129-36.
33. Leyden JJ, Marples RR, Kligman AM. Staphylococcus aureus in the lesions of atopic dermattis Br. J Dermatol 1974;90:525-30.
34. Lever R, Hadley K, Downey D, et al. Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy. Br J Dermatol 1988; 119:189-98.
35. Williams REA, Mackie RM. The staphylococci. Importance of their control in the management of skin disease, Dermatol Clin 1993;11:201-6.
36. Melnik G, Pelwig G. Tschung T. Are deficiencies PDE-Mediated immunoregulation involved in increased IgE synthesis of atopic mononuclear cells in vitro? Allergy 1991;46:502-6.
37. Businco L, Loppi M, Morse N, et al. Breast milk from mothers of children with newly developed atopic dermatitis has low levels of long chain polyunsaturated fatty acids J Allergy Clin Immunol 1993; 91:1134-9.
38. Berth-Jones J, Grahma Brown, RAC. Placebo controlled trial of essential fatty acids supplementation in atopic dermatitis, Lancet 1993;341:1557-60.
39. Jensen R, Ferris A, Lamni Keefe C, et al. Possible alleviation of atopic dermatitis in a breast fed infant by maternal supplementation with a fish oil concentrate J Pediatr Gastroenterol Nutr 1992;14:474-5.
40. Jensen Jarolin E, Ponlsen LK, With H, et al. Atopic dermatitis of the face scalp and neck, type I reaction of Pityrosporum ovale A, Allergy Clin Immunol 1992;89:44-51.
41. Savlainen J, Lamminatausta K, Kalimo K, et al. Candida albicans and atopic dermatitis, Clin Exp Allergy 1993;23: 332-9.
42. Braunstein WB, DeuellB, Platts Mills TAE. Atopic dermatitis associated with dermatophyte infection and Trichophyton hypersensitivity, Cutis 1993;51:191-2.
43. Svejgaard E, Faergman J, Jemec G, et al. Recent investigations on the relationship between funal skin disease and atopic dermatitis. Acta Dermatol Venereol (Stockh) 1989;144:140-4.
44. Jekler J, Larko O. Combined UVA-UVB phototherapy for atopic dermatitis, a paired comparison J Am Acad Dermatol 1990;22:49-53.
45. Jekler J, Phototherapy of atopic dermatitis with UV radiation Acta Dermatol Venereol (Stockh) 1992; 171:1-37.
46. Krutman J, Schopf E, High dose UVA1 phototherapy, a novel and highly effective approach for the treatment of acute exacerbation of atopic dermatitis, Acta Dermatol Venereol (Stockh) 1992;176:120-2.
47. Krutman J, C\zech W, Diepgen T, et al. High dose UVA1 therapy in the treatment of atopic dermatitis J Am Acad Dermatol 1992;26:225-30.
48. Sheehan MP, Atherton DJ, Morris P, et al. Oral psoralen photochemotherapy in severe childhood atopic dermatitis, an update Br. J Dermatol 1993;129:431-6.
49. Reinhold U, Wehrman W, Kukel S, et al. Evidence that defective inteferongamma production in atopic dermatitis patients is due to intrinsic abnormalities. Clin Exp Immunol 1990;79:374-79.
50. Reinhold U, Pawelec G, Wehrman W, et al. Immunoglobulin E and immunoglobulin G subclass distribution in vivo and relationship to in vitro generation of interferon gamma and neoprotein in patients with severe atopic dermatitis. Int Arch Allergy Appl Immunol 1988;87:120-6.
51. Boguniewicz M, Recombinant y-interferon in the treatment of patients with atopic dermatitis and elevated IgE levels. Am J Med. 1990;88:365-70.
52. Van Joost T, Stolz E, Muele F, Efficacy of low dose Cyclosporine in severe atopic disease, Arch Dermatol 1987;123:166-7.
53. Hannifin JM, Schnider L, Leung Y, et al. Recumbent y-interferon therapy for atopic dermatitis J Am Acad Dermatol 1993;28:189-97.
54. Ross JS,Camp RDR, Cyclosporin A in atopic dermatitis, Br J Dermatol 1990;122:41-5.
55. Wahlgren CF, Scheynius A, Hagermark O. Antipruritis effect of Cyclosporine A in atopic dermatitis Acta Dermatol Venereol (Stockh) 1990;70:323-9.
56. Salek MS, Finlay AY, Luscombe DK, et al. Cyclosporin greatly improves the quality of fe of adult with severe atopic dermatitis. A randomized double blind placebo controlled trial Br J Dermatol 1993;129:422-30.
57. Sepp N, Fritch PO. Can Cyclosporine A induce permanent remission of atopic dermatitis Br. J. Dermatol 1993;128:213-6.
58. Van Joost T, Kozel MA, Tank B, et al. Cyclosporine in atopic dermatitis, J Am Acad Dermatol 1992;27: 922-8.
59. Souillet G, Wehrmann W, Kukel S, et al. (-Interferon treatment in patients with hyper-IgE syndrome Lancet 1989 1:1384.
60. Torrelo A, Harto A. Sendagorta E et al. Interferon alpha therapy in atopic dermatitis Acta Dermatol Venereol (Stockh) 1992;72:370-2.
61. Jullien D, Nicolas JF, Frappaz A, et al. a-Interferon treatment in atopic dermatitis Acta Dermatol Venereol (Stockh) 1993;73:130-2.
62. Thrumoorthy T, Greaves MW. Disodium cromoglycate ointment in atopic eczema Br Med J 1978;2:500-1.
63. Kiamata H, Igarashi M. Topical cromoln solution in the treatment of young children with atopic dermatitis Clin Exp Allergy 1990;20:281-3.
64. Kiarnata H,Hiratsuka S. Effect of topical cromoglycate solution on atopic dermatitis. Combined treatment of sodium cromoglycate solution with the oral antiallergic medication, oxatomide Eur J Pediatr 1994;153:66-71.
65. Kang K, Cooper KD, Vanderbark A, et al. Thymopieotin pentapeptide improves the clinical parameters and lymphocyte subpocyte subpppulation in atopic dermatitis J. Am Acad Dermatol 1983; 8:372-7.
66. Leung DY, Hirsch RL, Schnider L, et al. Thymopentin therapy reduces the clinical severity of atopic dermatitis J. Allergy Clin Immunol 1990;85:927-33.
67. Harper J, White IR, Staughton R, et al. Thymostimulin (TP-1) therapy for atopic dermatitis Br. J Dermatol 1988;119 (Suppl 33):14.
68. Pannell R, Johson D, Travis J. isolation and properties of human a1-proteinase inhibitor. Biochemistry 1974 13: 5439-45.
69. Travis J, Salvsen GS. Human plasma proteinase inhibitors Ann Rev Bioch 1983;52:655-709.
70. Wachter A. Lezdey J. Treatment of atopic dermatitis with al - proteinase inhibitor Ann Allergy 1992; 69:407-414.
71. Leroy BP, Lachapelle J, Jacquemin M, et al. Treatmaent of atopic dermattitis by allergen antibody complexes, long term clinical results and evaluation of IgE antibodies, Dermatology 1992;184:271-4.
72. Leroy BP, Boden G, Jacquemin M et al. Allergen antibody complexes in treatment of atopic dermatitis Acta Dermatol Venereol (Stockh) 1992;176:129-36.
73. Berth-Jones J, Graham-Brown RA. Failure of papaverine to reduce pruritis in atopic dermatitis, a double blind placebo controlled, cross over study, Br J Dermatol 1990; 122: 553-7.
74. Takei S, Arora KY, Walker SM. Intravenous immunoglobulin contains specific antibodies inhibitory to activation of T cells by staphylococcal toxin superantigens J Clin Invest 1993;91:602-7.
75. Ehlayel M, Hidalgo H, Sorensen RU. Severe atopy and specific antibody deficiency, successful treatment with intravenous immunoglobulin Ann Allergy 1994;72:72.
76. Nueber K, Konigh W, Effects of staphylococcus aureus cell wall products (teichoic acid, peptidoglycan) and endotoxin-B on immunoglobulin synthesis (IgE,IgA,IgG) synthesis and CD23 expression in patients with atopic dermatitis Immunology 1992; 23-8.
77. Sheehan MP, Atherton DJ et al. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic dermatitis, Br J Dermatol 1992;126:179-84.
78. Kue-Hsiung H, Chen C,Hui-Feng H. Interleukin-2 therapy in severe atopic dermatitis J Clin Immunol 1991;11:22-8.