In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (Artesunate) in the treatment of malaria in Calabar, Nigeria

Central African Journal of Medicine

Volumn 42, Issue 4, 1996, Pages 109-111

  Ezedinachi, E N U ^a  

^a UNIVERSITY OF CALABAR   (Nigeria)

Author keywords

[No Author keywords available]

Indexed keywords

ARTESUNATE; CHLOROQUINE; FANSIDAR; HALOFANTRINE; PYRIMETHAMINE; SULFADOXINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FOLLOW UP; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALARIA; NIGERIA; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ANTIMALARIALS; ARTEMISININS; CHILD; CHLOROQUINE; DRUG COMBINATIONS; DRUG RESISTANCE; HUMANS; MALARIA, FALCIPARUM; NIGERIA; PHENANTHRENES; PYRIMETHAMINE; SESQUITERPENES; SULFADOXINE; TIME FACTORS; URBAN HEALTH;

EID: 0029978593     PISSN: 00089176     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Ekanem OJ, Weisfeld JS, Salako LA, Nahlen BL, Ezedinachi ENU, Walker O, et al Sensitivity of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in Nigeria children. Bull WHO 1990; 68(1):45-52.
2. Ezedinachi ENU, Ejezie, GC. Current concepts on the prevention and treatment of malaria in W. Africa. Post Grad Doctor Africa 1990; 12:26-32.
3. Spencer HC. Drug resistant malaria changing patterns mean difficult decisions. Trans R Soc Trop Med Hyg 1985; 79:748-58.
4. Salako LA, Aderounmu, AFC. In vitro chloroquine and mefloquine resistant Plasmodium falciparum in Nigeria. Lancet 1987;1:572-3.
5. Lege-Oguntope L, Adagu SI Werblinska B. Ogala WN, Slotboom AB. Resistance of Plasmodium falciparum to sulphadoxine-pyrimethamine combination in semi-immune children of Zaria, Northern Nigeria. Trans R Soc Trop Med Hyg 1990;84:505-6.
6. Keuter M, van Eijk A, Hoogstrate, M Raasveld, M. va de Ree M, Ngwawe WA, et al. Comparison of chloroquine, pyrimethamine and sulfadoxine, and chlorproguanil and dapsone as treatment for falciparum malaria in pregnant and no-pregnant women, Kakamega district, Kenya. Br Med J 1990;301:466-70.
7. Ezedinachi ENU, Ejezie GC, Usanga EA, Gemade EII, Ikapatt NW, Alaribe AAA. New trends in chloroquine efficacy in the treatment of malaria: chloroquine resistant P. falciparum in Anambra and Benue States of Nigeria. Cent Afr J Med 1991;37:180-18.
8. World Health Organisation. Chemotherapy of malaria and resistance to antimalarial. Technical Report Serial No. 529, 1973:30-55.
9. National Guidelines for Malaria control Nigeria: Federal Ministry of Health, 1990.
10. Umotong AB, Ezedinachi ENU, Okerengwo AA, Usanga EA, Udo JJ, Williams AIO. Correlation between in vivo and in vitro response of chloroquine-resistant Plasmodium falciparum in Calabar, South-Eastern Nigeria. Acta Trop 1991;49:119-25.