5′-C-branched thymidines: Synthesis, stereochemistry, and incorporation into oligodeoxynucleotides

Tetrahedron Letters

Volumn 37, Issue 16, 1996, Pages 2739-2742

  Wang, Guangyi ^a   Middleton, Patrick J ^a  

^a Valeant Pharmaceuticals International   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGODEOXYNUCLEOTIDE; THYMIDINE DERIVATIVE;

ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; HYBRIDIZATION; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0029978365     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00418-2     Document Type: Article

References (14)

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14. 3R is the (5′R)-isomer of 3S (not shown in Scheme 2), which was subject to the same transformations as 3S to yield the phosphoramidite 23R.