Combined treatment with a new biscarbodithioate C9G2DTC and BGDTC for mobilizing cadmium deposits in rats

Journal of Applied Toxicology

Volumn 16, Issue 2, 1996, Pages 157-158

  Kostial, Krista ^a   Piasek, Martina ^a   Blanuša, Maja ^a   Schönwald, Neala ^a   Jones, Mark M ^b   Singh, Pramod K ^b  

^a INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Cadmium; Chelation; Disodium N,N' bis(D glucosyl) 1,9 nonanediamine'N,N' biscarbodithioate (C9G2DTC); Rats; Sodium N benzyl D glucamine N carbodithioate (BGDTC)

Indexed keywords

CADMIUM; CHELATING AGENT; N BENZYL D GLUCAMINE N CARBODITHIOATE; N,N' BIS(DEXTRO GLUCOSYL) 1,9 NONANEDIAMINE N,N' BISCARBODITHIOATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CHELATION; CONTROLLED STUDY; FEMALE; INTOXICATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY; LIVER; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICOKINETICS;

ANIMALS; BRAIN; CADMIUM CHLORIDE; CADMIUM RADIOISOTOPES; CHELATING AGENTS; DRUG SYNERGISM; FEMALE; GLUCOSIDES; KIDNEY; LIVER; RATS; RATS, WISTAR; SORBITOL; THIOCARBAMATES;

EID: 0029978130     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199603)16:2<157::AID-JAT322>3.0.CO;2-Q     Document Type: Article

References (3)

1. P. K. Singh, C. C. Xu, M. M. Jones, K. Kostial and M. Blanuša, Molecular-modeling design of cadmium-mobilizing agents: a novel biscarbodithioate. Chem. Res. Toxicol. 7, 614-620 (1994).
2. S. Kojima, K. Kammaka, M. Kiyozumi and T. Honda, Comparative effects of three chelating agents on distribution and excretion of cadmium in rats. Toxicol. Appl. Pharmacol. 83, 516-524 (1986).
3. S. Kojima, M. Kiyozumi, T. Honda, K. Kaminaka, Y. Oda and Y. Senba, Effect of N-benzyl-D-glucamine dithiocarbamate on distribution and excretion of cadmium in rats. Toxicology 45, 93-102 (1987).