Analysis of effector mechanisms in murine cardiac allograft rejection

Transplant Immunology

Volumn 4, Issue 1, 1996, Pages 46-48

  Alexander, D Z ^a   Pearson, T C ^a   Hendrix, R ^a   Ritchie, S C ^a   Larsen, Christian P ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; NITRIC OXIDE SYNTHASE; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; B LYMPHOCYTE; CONFERENCE PAPER; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; GRAFT REJECTION; HEART GRAFT; HEART TRANSPLANTATION; ISOGRAFT; MACROPHAGE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0029977647     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(96)80033-5     Document Type: Conference Paper

References (21)

1. Dallman MJ, Morris PJ. The immunology of rejection. In: Morris PJ ed. Kidney transplantation: principles and practice, fourth edition Philadelphia: WB Saunders, 1994: 8-25.
2. Larsen CP, Alexander DZ, Hendrix R, Ritchie SC, Pearson TC. Fas-mediated cytotoxicity. An immunoeffector or immunoregulatory pathway in T cell-mediated immune responses? Transplan tation 1995; 60: 221-24.
3. Bolton EM, Gracie JA, Briggs JD, Kampinga J, Bradley JA. Cellular requirements for renal allograft rejection in the athymic nude rat. J Exp Med 1989; 169: 1931-46.
4. Gracie JA, Bolton EM, Porteous C, Bradley JA. T cell requirements for the rejection of renal allografts bearing an isolated class I MHC disparity. J Exp Med 1990; 173: 1547-57.
5. Suda T, Nagata S. Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 1994; 179: 873-79.
6. Hanabuchi S, Koyanagi M, Kawasaki A et al. Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci USA 1994; 91: 4930-34.
7. Kagi D, Vignaux F, Ledermann B et al. Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994; 265: 528-30.
8. Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perform and Fas lytic pathways. Nature 1994; 370: 650-52.
9. Cony RJ, Winn HJ, Russell PS. Primarily vascularized allografts of hearts in mice: the role of H-2D, H-2K, and non H-2 antigens in rejection. Transplantation 1973; 16: 343-50.
10. Dallman MJ, Montgomery RA, Larsen CP, Wanders A, Wells AF. Cytokine gene expression: analysis Northern blotting, polymerase chain reaction, and in situ hybridization. Immunol Rev 1991; 119: 163-79.
11. Larsen CP, Ritchie SC, Hendrix R et al. Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. J Immunol 1994; 152: 5208-19.
12. Witsell AL, Schook LB. Clonal analysis of gene expression by PCR. BioTechniques 1990; 9: 318-21.
13. Ju S-T, Panka DJ, Cui H et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995; 373: 444-48.
14. O'Connell P, Pacheco-Silva A, Nickerson P et al. Unmodified pancreatic islet allograft rejection results in the preferential expression of certain T cell activation transcripts. J Immunol 1993; 150: 1093-104.
15. Shinkai Y, Takio K, Okumura K. Homology of perform to the ninth component of complement. Nature 1988; 334: 525-27.
16. Takahashi T, Tanaka M, Brannan CI et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994; 76: 969-76.
17. Stenger S, Thuring H, Rollinghoff M, Bogdan C. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J Exp Med 1994; 180: 783-93.
18. Pearson TC, Alexander DZ, Winn KJ, Linsley PS, Lowry RP, Larsen CP, Transplantation tolerance induced by CTLA4-Ig. Transplantation 1994; 57: 1701-706,
19. Worrall NK, Lazenby WD, Misko TP et al. Modulation of in vivo alloreactivity by inhibition of inducible ntiric oxide synthase, J Exp Med 1995; 181: 63-70.
20. Lowry R, Blais D. Tumor necrosis factor-alpha in rejecting rat cardiac allografts. Transplant Proc 1988; 20: 245.
21. + cytotoxic T cells. Proc Natl Acad Sci USA 1994; 91: 4185-89.