메뉴 건너뛰기




Volumn 720, Issue 1-2, 1996, Pages 69-74

Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors

Author keywords

GluR6; Kainate; NBQX; SYM2081; Toxicity

Indexed keywords

4 METHYLGLUTAMIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; KAINIC ACID; KAINIC ACID RECEPTOR; UNCLASSIFIED DRUG;

EID: 0029977515     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00115-1     Document Type: Article
Times cited : (3)

References (34)
  • 1
    • 0027085867 scopus 로고
    • Mechanisms of excitotoxicity in neurologic disease
    • Beal, M.F., Mechanisms of excitotoxicity in neurologic disease, FASEB J., 6 (1992) 3338-3344.
    • (1992) FASEB J. , vol.6 , pp. 3338-3344
    • Beal, M.F.1
  • 2
    • 0029240274 scopus 로고
    • Review: Neurotransmitter receptors. II. AMPA and kainate receptors
    • Bettler, B. and Mulle, C., Review: neurotransmitter receptors. II. AMPA and kainate receptors, Neuropharmacology, 34 (1995) 123-139.
    • (1995) Neuropharmacology , vol.34 , pp. 123-139
    • Bettler, B.1    Mulle, C.2
  • 4
    • 0029065657 scopus 로고
    • AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity
    • Brorson, J.R., Manzolillo, P.A., Gibbons, S.J. and Miller, R.J., AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity, J. Neurosci., 15 (1995) 4515-4524.
    • (1995) J. Neurosci. , vol.15 , pp. 4515-4524
    • Brorson, J.R.1    Manzolillo, P.A.2    Gibbons, S.J.3    Miller, R.J.4
  • 5
    • 0026612030 scopus 로고
    • The effects of kainate and the glutamate agonist, AMPA, are not separable in rat neocortical cultures
    • Cai, N.-S. and Erdo, S.L., The effects of kainate and the glutamate agonist, AMPA, are not separable in rat neocortical cultures, Neurosci. Lett., 141 (1992) 57-60.
    • (1992) Neurosci. Lett. , vol.141 , pp. 57-60
    • Cai, N.-S.1    Erdo, S.L.2
  • 6
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity in cortical cell culture
    • Choi, D.W., Ionic dependence of glutamate neurotoxicity in cortical cell culture. J. Neurosci., 7 (1987) 369-379.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 7
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi, D.W., Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage, Trends Neurosci., 11 (1988) 465-469.
    • (1988) Trends Neurosci. , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 8
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cultures: Attenuation by NMDA antagonists
    • Choi, D.W., Koh, J.Y. and Peter, S., Pharmacology of glutamate neurotoxicity in cortical cultures: attenuation by NMDA antagonists, J. Neurosci., 8 (1988) 185-196.
    • (1988) J. Neurosci. , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.Y.2    Peter, S.3
  • 9
    • 0020640626 scopus 로고
    • Neurotoxic action of kainic acid
    • Coyle. J.T., Neurotoxic action of kainic acid, J. Neurochem., 41 (1983) 1-11.
    • (1983) J. Neurochem. , vol.41 , pp. 1-11
    • Coyle, J.T.1
  • 10
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot, F. and Lang, R., Rapid colorimetric assay for cell growth and survival: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability, J. Immunol. Methods, 89 (1986) 271-277.
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 11
    • 0027339321 scopus 로고
    • 2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6
    • 2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6, Proc. Natl. Acad. Sci. USA, 90 (1993) 755-759.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 755-759
    • Egebjerg, J.1    Heinemann, S.2
  • 12
    • 0029045977 scopus 로고
    • Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: Selective probes of kainate receptors
    • Gu, Z.-Q., Hesson, D.P., Pelletier, J.C., Maccecchini, M.-L., Zhou, L.-M. and Skolnick, P., Synthesis, resolution, and biological evaluation of the four stereoisomers of 4-methylglutamic acid: selective probes of kainate receptors, J. Med. Chem., 38 (1995) 2518-2520.
    • (1995) J. Med. Chem. , vol.38 , pp. 2518-2520
    • Gu, Z.-Q.1    Hesson, D.P.2    Pelletier, J.C.3    Maccecchini, M.-L.4    Zhou, L.-M.5    Skolnick, P.6
  • 13
    • 0026530085 scopus 로고
    • The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
    • Herb, A., Burnashev, N., Werner, P., Sakmann, B., Wisden, W. and Seeburg, P.H., The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits, Neuron, 8 (1992) 775-785.
    • (1992) Neuron , vol.8 , pp. 775-785
    • Herb, A.1    Burnashev, N.2    Werner, P.3    Sakmann, B.4    Wisden, W.5    Seeburg, P.H.6
  • 14
    • 0025923461 scopus 로고
    • 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition
    • 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition, Science, 252 (1991) 851-853.
    • (1991) Science , vol.252 , pp. 851-853
    • Hollmann, M.1    Hartley, M.2    Heinemann, S.3
  • 16
    • 0029009922 scopus 로고
    • The responsiveness of a tetracycline-sensitive expression system differs in different cell lines
    • Howe, J.R., Skryabin, B.V., Belcher, S.M. and Zerillo, C.A., Schmauss, C., The responsiveness of a tetracycline-sensitive expression system differs in different cell lines, J. Biol. Chem., 270 (1995) 14168-14174.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14168-14174
    • Howe, J.R.1    Skryabin, B.V.2    Belcher, S.M.3    Zerillo, C.A.4    Schmauss, C.5
  • 17
    • 85030198447 scopus 로고    scopus 로고
    • Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances
    • in press
    • Howe, J.R., Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances, J. Neurophysiol., in press..
    • J. Neurophysiol.
    • Howe, J.R.1
  • 18
    • 0025885342 scopus 로고
    • Antagonism of non-NMDA receptors augment the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose
    • Kaku, D.A., Goldberg, M.P. and Choi, D.W., Antagonism of non-NMDA receptors augment the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose, Brain Res., 554 (1991) 344-347.
    • (1991) Brain Res. , vol.554 , pp. 344-347
    • Kaku, D.A.1    Goldberg, M.P.2    Choi, D.W.3
  • 19
    • 0025959374 scopus 로고
    • Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures
    • Kato, K., Puttfarcken, P.S., Lyons, W.E. and Coyle, J.T., Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures, J. Pharmacol. Exp. Ther., 256 (1991) 402-411.
    • (1991) J. Pharmacol. Exp. Ther. , vol.256 , pp. 402-411
    • Kato, K.1    Puttfarcken, P.S.2    Lyons, W.E.3    Coyle, J.T.4
  • 20
    • 0025341925 scopus 로고
    • Non-NMDA receptor-mediated neurotoxicity in cortical culture
    • Koh, J.Y., Goldberg, M.P., Hartley, D.M. and Choi, D.W., Non-NMDA receptor-mediated neurotoxicity in cortical culture, J. Neurosci., 10 (1990) 693-705.
    • (1990) J. Neurosci. , vol.10 , pp. 693-705
    • Koh, J.Y.1    Goldberg, M.P.2    Hartley, D.M.3    Choi, D.W.4
  • 21
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • Koh, J. and Choi, D.W., Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay, J. Neurosci. Methods, 20 (1987) 83-90.
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.1    Choi, D.W.2
  • 22
    • 0025831357 scopus 로고
    • Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death
    • Koh, J.-Y. and Choi, D.W., Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death, Brain Res., 548 (1991) 318-321.
    • (1991) Brain Res. , vol.548 , pp. 318-321
    • Koh, J.-Y.1    Choi, D.W.2
  • 23
    • 0023433171 scopus 로고
    • Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo-III
    • Mayer, M.L., MacDermott, A.B., Westbrook, G.L., Smith, S.J. and Barker, J.L., Agonist-and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo-III, J. Neurosci., 7 (1987) 3230-3244.
    • (1987) J. Neurosci. , vol.7 , pp. 3230-3244
    • Mayer, M.L.1    MacDermott, A.B.2    Westbrook, G.L.3    Smith, S.J.4    Barker, J.L.5
  • 24
    • 0025221685 scopus 로고
    • A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties
    • Nakanishi, N., Shneider, N.A. and Axel, R., A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties, Neuron, 5 (1990) 569-581.
    • (1990) Neuron , vol.5 , pp. 569-581
    • Nakanishi, N.1    Shneider, N.A.2    Axel, R.3
  • 25
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications for brain function
    • Nakanishi, S., Molecular diversity of glutamate receptors and implications for brain function, Science, 258 (1992) 597-603.
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 26
    • 0028983524 scopus 로고
    • Are NMDA or AMPA/kainate receptor antagonists more efficacious in delayed treatment of excitotoxic neuronal injury?
    • Prehn, J.H.M., Lippert, K. and Krieglstein, J., Are NMDA or AMPA/kainate receptor antagonists more efficacious in delayed treatment of excitotoxic neuronal injury?, Eur. J. Pharmacol., 292 (1995) 179-189.
    • (1995) Eur. J. Pharmacol. , vol.292 , pp. 179-189
    • Prehn, J.H.M.1    Lippert, K.2    Krieglstein, J.3
  • 27
    • 0028011941 scopus 로고
    • The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture
    • Regan, R.F. and Choi, D.W., The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture, Brain Res., 633 (1994) 236-242.
    • (1994) Brain Res. , vol.633 , pp. 236-242
    • Regan, R.F.1    Choi, D.W.2
  • 28
    • 0024406708 scopus 로고
    • Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex
    • Rosenberg, P.A. and Aizenman, E., Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex, Neurosci. Lett., 103 (1989) 162-168.
    • (1989) Neurosci. Lett. , vol.103 , pp. 162-168
    • Rosenberg, P.A.1    Aizenman, E.2
  • 29
    • 0023261234 scopus 로고
    • Delayed neurotoxicity of excitotoxic amino acids in vitro
    • Rothman, S.M., Thurston, J.H. and Hauhart, R.E., Delayed neurotoxicity of excitotoxic amino acids in vitro, Neuroscience, 22 (1987) 472-480.
    • (1987) Neuroscience , vol.22 , pp. 472-480
    • Rothman, S.M.1    Thurston, J.H.2    Hauhart, R.E.3
  • 30
    • 0025117827 scopus 로고
    • 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline: A neuroprotectant for cerebral ischemia
    • Sheardown, M.J., Nielson, E.O., Hansen, A.J., Jacobson, P. and Honore, T., 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline: a neuroprotectant for cerebral ischemia, Science, 247 (1990) 571-574.
    • (1990) Science , vol.247 , pp. 571-574
    • Sheardown, M.J.1    Nielson, E.O.2    Hansen, A.J.3    Jacobson, P.4    Honore, T.5
  • 31
    • 0027080523 scopus 로고
    • Complex pharmacological properties of recombinant α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes
    • Stein, E., Cox, J.A., Seeburg, P.H. and Verdoorn, T.A., Complex pharmacological properties of recombinant α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes, Mol. Pharmacol., 42 (1992) 864-871.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 864-871
    • Stein, E.1    Cox, J.A.2    Seeburg, P.H.3    Verdoorn, T.A.4
  • 33
    • 0028988526 scopus 로고
    • Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors mediate cytotoxicity in the oligodendroglial lineage
    • Yoshioka, A., Hardy, M., Younkin, D.P., Grinspan, J.B., Stern, J.L. and Pleasure, D., Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors mediate cytotoxicity in the oligodendroglial lineage, J. Neuorchem., 64 (1995) 2442-2448.
    • (1995) J. Neuorchem. , vol.64 , pp. 2442-2448
    • Yoshioka, A.1    Hardy, M.2    Younkin, D.P.3    Grinspan, J.B.4    Stern, J.L.5    Pleasure, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.