Peptide amidating activity in human bronchoalveolar lavage fluid

Lung Cancer

Volumn 14, Issue 2-3, 1996, Pages 239-251

  Scott, Frank M ^a   Treston, Anthony M ^a   Shaw, Gail L ^c   Avis, Ingalill ^a   Sorenson, Julie ^b   Kelly, Karen ^b   Dempsey, Edward C ^b   Cantor, Alan B ^c   Tockman, Melvyn ^d   Mulshine, James L ^a  

^a Biomarkers and Prev Research Branch   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Biomarkers; Prevention; Translational research

Indexed keywords

ALPHA AMIDATING ENZYME;

ARTICLE; CANCER CELL CULTURE; CANCER RISK; CLUSTER ANALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; FOLLOW UP; HUMAN; HUMAN CELL; LUNG CANCER; LUNG LAVAGE; PREDICTION; PRIORITY JOURNAL; SECOND CANCER;

EID: 0029977416     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-5002(96)00550-8     Document Type: Article

References (37)

1. Baserga R. Oncogenes and the strategy of growth factors. Cell 1994; 79: 927-930.
2. Tabassian AR, Snider RH, Nylen ES et al. Heterogeneity studies of hamster calcitonin following acute exposure to cigarette smoke: evidence for monomeric secretion. Anat Rec 1993; 236: 253-256.
3. Linnoila RI, Mulshine JL, Steinberg SM et al. Neuroendocrine differentiation in endocrine and nonendocrine lung carcinomas. Am J Clin Pathol 1988; 90: 1-12.
4. Mulshine JL, Linnoila RI, Magnani JL. Applications of monoclonal antibodies in the management of lung cancer patients: an analysis. Chest Surg Clin North Am 1991; 1: 153-189.
5. Eipper BA, Stoffers DA, Mains RE. The biosynthesis of neuropeptides: peptide α-amidation. Annu Rev Neurosci 1992; 15: 57-85.
6. Cuttitta F, Carney DN, Mulshine J et al. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature (Lond) 1985; 316: 823-826.
7. Siegfried JM, Han YH, DeMichele MA et al. Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum-free and growth factor-free conditions. J Biol Chem 1994; 269: 8596-8603.
8. Willey JC, Lechner JF, Harris CC. Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells. Exp Cell Res 1984; 153: 245-248.
9. Sunday ME, Hua J, Dai HB et al. Bombesin increases fetal lung growth and maturation in utero and in organ culture. Am J Respir Cell Mol Biol 1990; 3: 199-205.
10. Aguayo SM, Kane MA, King TE et al. Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers. J Clin Invest 1989; 84: 1105-1113.
11. Bradbury AF, Finnie MDA, Smyth DG. Mechanism of C-terminal amide formation by pituitary enzymes. Nature (Lond) 1982; 298: 686-688.
12. Eipper BA, Mains RE, Glembotski CC. Identification in pituitary tissue of a peptide α-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid. Proc Natl Acad Sci USA 1983; 80: 5144-5148.
13. Mizuno K, Ohsuye K, Wada Y et al. Cloning and sequence of cDNA encoding a peptide C-terminal α-amidating enzyme from Xenopus laevis. Biochem Biophys Res Commun 1987; 148: 546-552.
14. Stoffers DA, Green CB-R, Eipper BA. Alternative mRNA splicing generates multiple forms of peptidyl-glycine α-amidating monooxygenase in rat atrium. Proc Natl Acad Sci 1989; 86: 735-739.
15. Perkins SN, Eipper BA, Mains RE. Stable expression of full-length and truncated bovine peptidyl-glycine α-amidating monooxygenase complementary DNAs in cultured cells. Mol Endocrinol 1990; 4: 132-139.
16. Treston AM, Scott FM, Vos M et al. Biochemical characterization of peptide α-amidating activities of human neuroendocrine lung cancer cell lines. Cell Growth Differ 1993; 4: 911-920.
17. Glauder J, Ragg H, Rauch J et al. Human peptidyl-glycine α-amidating monooxygenase: c-DNA, cloning and functional expression of a truncated form in COS cells. Biochem Biophys Res Commun 1990; 169: 551-558.
18. Noguchi M, Takahashi K, Okamoto H. Rat peptidylglycine α-amidating enzyme: the relation between activities at neutral and alkaline pH values. Arch Biochem Biophys 1989; 275: 505-513.
19. Takahashi K, Okamoto H, Seino H. Peptidylglycine α-amidating reaction: evidence for a two-step mechanism involving a stable intermediate at neutral pH. Biochem Biophys Res Commun 1990; 169: 524-530.
20. Katopodis AG, Ping D, May SW. A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of α-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine α-amidating monooxygenase in peptide amidation. Biochemistry 1990; 29: 6115-6120.
21. Murthy ASN, Mains RE, Eipper BA. Purification and characterization of peptidylglycine α-amidating monooxygenase from bovine neurointermediate pituitary. J Biol Chem 1986; 261: 1815-1822.
22. Eipper BA, Perkins SN. Husten EJ et al. Peptidyl-α-hydroxyglycine α-amidating lyase. Purification, characterization and expression. J Biol Chem 1991; 266: 7827-7833.
23. Tockman MS, Erozan YS, Gupta P, Piantadosi S, Mulshine JL, Ruckdeschel JC, the LCEDWG Investigators. The early detection of second primary lung cancers by sputum immunostaining. Chest 1994; 106 (6 Suppl): 385S-390S.
24. Scott F, Treston AM, Quinn K et al. Peptide amidating activity in human bronchoalveolar lavage fluid. Proceedings of the AACR 1993; 34: 552, Abstract #3289.
25. Scott F, Cuttitta F, Treston AM et al. Prospective trial evaluating immunocytochemical-based sputum techniques for early lung cancer detection: assays for promotion factors in the bronchial lavage. J Cell Biochem 1993: Suppl 17F: 175-183.
26. Mountain CF. A new international staging system for lung cancer. Chest 1986; 89: 225S-233S.
27. 14C]carboxyl-labeled amino acids. Anal Biochem 1978; 84: 638-641.
28. Saldise L, Martinez A, Montuenga LM, Treston A et al. Distribution of peptidyl-glycine α-amidating monooxygenase (PAM) enzymes in normal lung and in lung epithelial tumors. J Histochem Cytochem 1996; 44: 3-12.
29. Kasprzyk PG, Cuttitta F, Avis I et al. Solid phase peptide quantitation assay using labeled monoclonal antibody and glutaraldehyde fixation. Anal Biochem 1988; 174: 224-234.
30. SAS/STAT User's Guide Release 6.03. Cary, NC: SAS Institute, Inc., 1988; 283-292.
31. Vos MD, Scott FM, Iwai N, Treston AM. Expression in human lung cancer cell lines of genes of prohormone processing and the neuroendocrine phenotype. J Cell Biochem 1996; Suppl: in press.
32. Graziano SL, Tatum AH, Newman NB et al. The prognostic significance of neuroendocrine markers and carcinoembryonic antigen in patients with resected stage I and II non-small cell lung cancer. Cancer Res 1994; 54: 2908-2913.
33. Sundaresan V, Reeve JG, Stenning S et al. Neuroendocrine differentiation and clinical behaviour in non-small cell lung tumours. Br J Cancer 1991; 64: 333-338.
34. Hunninghake GW, Gadek JE, Kawanami O et al. Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage. Am J Pathol 1979; 97: 149-206.
35. Husten EJ, Tausk FA, Keutmann HT. Use of endoproteases to identify catalytic domains, linker regions, and functional interactions in soluble peptidylglycine α-amidating monooxygenase. J Biol Chem 1993; 268: 9709-9717.
36. Bergman B, Brezicka F-T, Engstrom C-P. Clinical usefulness of serum assays of neuron-specific enolase, carcinoembryonic antigen and CA-50 antigen in the diagnosis of lung cancer. Eur J Cancer 1993; 29A: 198-202.
37. Tockman MS, Gupta PK, Myers JD et al. Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: a new approach to early lung cancer detection. J Clin Oncol 1988; 6: 1685-1693.