2,5-diarylisothiazolone: Novel inhibitors of cytokine-induced cartilage destruction

Bioorganic and Medicinal Chemistry

Volumn 4, Issue 6, 1996, Pages 851-858

  Wright, Stephen W ^a,b   Petraitis, Joseph J ^a   Freimark, Bruce ^a   Giannaras, John V ^a   Pratta, Michael A ^a   Sherk, Susan R ^a   Williams, Jean M ^a   Magolda, Ronald L ^a   Arner, Elizabeth C ^a  

^a DUPONT COMPANY   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINOPHENYL) 5 PHENYLISOTHIAZOL 3 ONE; 2,4,5 TRIPHENYLISOTHIAZOL 3 ONE; 2,5 DIPHENYLISOTHIAZOL 3 ONE; 5 PHENYL 2 TOLYLISOTHIAZOL 3 ONE; INDOMETACIN; ISOTHIAZOLE DERIVATIVE; NAPROXEN; PHENIDONE; RECOMBINANT INTERLEUKIN 1BETA; STROMELYSIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARTILAGE DEGENERATION; CATTLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG SYNTHESIS; LIVER MICROSOME; NONHUMAN; NOSE SEPTUM; ORGAN CULTURE; OSTEOARTHRITIS; STRUCTURE ACTIVITY RELATION;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0029977407     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/0968-0896(96)00053-3     Document Type: Article

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