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Volumn 25, Issue 2, 1996, Pages 363-372

Cyclooxygenase-2 inhibitors: A new class of anti-inflammatory agents that spare the gastrointestinal tract

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; DEXAMETHASONE; ICOSANOID; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBOXANE A2;

EID: 0029977379     PISSN: 08898553     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8553(05)70252-1     Document Type: Article
Times cited : (124)

References (35)
  • 1
    • 0028032723 scopus 로고
    • COX-1 and COX-2: Toward the development of more selective NSAIDs
    • B. Battistini R. Botting Y.S. Bakhle COX-1 and COX-2: Toward the development of more selective NSAIDs Drugs News Prespect 7 1995 501 512
    • (1995) Drugs News Prespect , vol.7 , pp. 501-512
    • Battistini, B.1    Botting, R.2    Bakhle, Y.S.3
  • 2
    • 0026498268 scopus 로고
    • The gastroduodenal safety and efficacy of the fixed combination of diclofenac and misoprostol in the treatment of osteoarthritis
    • W. Bolten J.A.M. Gomes H. Stead The gastroduodenal safety and efficacy of the fixed combination of diclofenac and misoprostol in the treatment of osteoarthritis Br J Rheumatol 31 1992 753 758
    • (1992) Br J Rheumatol , vol.31 , pp. 753-758
    • Bolten, W.1    Gomes, J.A.M.2    Stead, H.3
  • 3
    • 85113062534 scopus 로고
    • Metabolite measurement as an index of prostaglandin synthesis in vivo
    • A.R. Brash Metabolite measurement as an index of prostaglandin synthesis in vivo J.M. Boeynaems A.G. Herman Prostaglandins, Prostacyclin and Thromboxane Measurement 1980 Martinus Nijhoff London 137 138
    • (1980) , pp. 137-138
    • Brash, A.R.1
  • 4
    • 0020574356 scopus 로고
    • From experiment to experience: Side effects of non-steroidal anti-inflammatory drugs
    • L.S. Coles J.F. Fries R.G. Kraines From experiment to experience: Side effects of non-steroidal anti-inflammatory drugs Am J Med 74 1983 820 828
    • (1983) Am J Med , vol.74 , pp. 820-828
    • Coles, L.S.1    Fries, J.F.2    Kraines, R.G.3
  • 5
    • 0028139275 scopus 로고
    • Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
    • R.A. Copeland J.M. Williams J. Giannaras Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase Proc Natl Acad Sci USA 91 1994 11202 11206
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11202-11206
    • Copeland, R.A.1    Williams, J.M.2    Giannaras, J.3
  • 6
    • 0028213334 scopus 로고
    • Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues
    • L.J. Crofford R.L. Wilder A.P. Ristimaki Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues J Clin Invest 93 1994 1095 1101
    • (1994) J Clin Invest , vol.93 , pp. 1095-1101
    • Crofford, L.J.1    Wilder, R.L.2    Ristimaki, A.P.3
  • 7
    • 0026620334 scopus 로고
    • The safety of arthrotec in patients with rheumatoid arthritis or osteoarthritis: An assessment of the upper gastrointestinal tract by endoscopy
    • J.A. DeMelo Gomes The safety of arthrotec in patients with rheumatoid arthritis or osteoarthritis: An assessment of the upper gastrointestinal tract by endoscopy Scand J Rheumatol 21 suppl 96 1992 23 31
    • (1992) Scand J Rheumatol , vol.21 , Issue.suppl 96 , pp. 23-31
    • DeMelo Gomes, J.A.1
  • 8
    • 0026702494 scopus 로고
    • Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10 encoded protein is a functional prostaglandin G/H synthase
    • B.S. Fletcher D.A. Kujubu D.M. Perrin Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10 encoded protein is a functional prostaglandin G/H synthase J Biol Chem 267 1992 4338 4344
    • (1992) J Biol Chem , vol.267 , pp. 4338-4344
    • Fletcher, B.S.1    Kujubu, D.A.2    Perrin, D.M.3
  • 9
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • 2 synthase (cyclooxygenase) in human monocytes J Biol Chem 265 1990 16737 16740
    • (1990) J Biol Chem , vol.265 , pp. 16737-16740
    • Fu, J.1    Masferrer, J.L.2    Seibert, K.3
  • 10
    • 0027516402 scopus 로고
    • NS-398, a novel nonsteroidal antiinflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
    • N. Futaki S. Takanashi M. Yokohama NS-398, a novel nonsteroidal antiinflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions Gen Pharmacol 24 1993 105 110
    • (1993) Gen Pharmacol , vol.24 , pp. 105-110
    • Futaki, N.1    Takanashi, S.2    Yokohama, M.3
  • 11
    • 0028089109 scopus 로고
    • NS-398, a new antiinflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro
    • N. Futaki S. Takanashi M. Yokohama NS-398, a new antiinflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro Prostaglandins 47 1994 55 59
    • (1994) Prostaglandins , vol.47 , pp. 55-59
    • Futaki, N.1    Takanashi, S.2    Yokohama, M.3
  • 12
    • 0025160887 scopus 로고
    • Anti-inflammatory and safety profile of DuP 697, a novel orally active effective prostaglandin synthesis inhibitor
    • K.R. Gans W. Galbraith R.J. Roman Anti-inflammatory and safety profile of DuP 697, a novel orally active effective prostaglandin synthesis inhibitor Pharm Exp Ther 254 1990 180 187
    • (1990) Pharm Exp Ther , vol.254 , pp. 180-187
    • Gans, K.R.1    Galbraith, W.2    Roman, R.J.3
  • 13
    • 0028830109 scopus 로고
    • Expression and selective inhibition of the constitutive and inducible forms of human cyclooxygenase
    • J.K. Gierse S.D. Hauser D.P. Creely Expression and selective inhibition of the constitutive and inducible forms of human cyclooxygenase Biochem J 305 1995 479 484
    • (1995) Biochem J , vol.305 , pp. 479-484
    • Gierse, J.K.1    Hauser, S.D.2    Creely, D.P.3
  • 14
    • 0027494252 scopus 로고
    • Duodenal and gastric ulcer prevention with misoprostol in arthritis patients taking NSAIDs
    • D.Y. Graham R.H. White L.W. Moreland Duodenal and gastric ulcer prevention with misoprostol in arthritis patients taking NSAIDs Ann Intern Med 119 1993 257 262
    • (1993) Ann Intern Med , vol.119 , pp. 257-262
    • Graham, D.Y.1    White, R.H.2    Moreland, L.W.3
  • 15
    • 0027421621 scopus 로고
    • Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2
    • A. Habib C. Creminon Y. Frobert Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2 J Biol Chem 268 1993 23448 23454
    • (1993) J Biol Chem , vol.268 , pp. 23448-23454
    • Habib, A.1    Creminon, C.2    Frobert, Y.3
  • 16
    • 0028034970 scopus 로고
    • Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
    • R.C. Harris J.A. McKanna Y. Akai Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction J Clin Invest 94 1994 2504 2510
    • (1994) J Clin Invest , vol.94 , pp. 2504-2510
    • Harris, R.C.1    McKanna, J.A.2    Akai, Y.3
  • 17
    • 0000375207 scopus 로고
    • Adrenocorticotropic hormone; Adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and actions of adrenocortical hormones
    • R.C. Haynes Adrenocorticotropic hormone; Adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and actions of adrenocortical hormones A.G. Gilman T.W. Rall S. Nies Goodman and Gilman's the Pharmacological Basis of Therapeutics 1990 Pergamon New York 1431 1462
    • (1990) , pp. 1431-1462
    • Haynes, R.C.1
  • 18
    • 0028555837 scopus 로고
    • Regulation of prostaglandin synthase-1 and prostaglandin synthase-2
    • H.R. Herschman Regulation of prostaglandin synthase-1 and prostaglandin synthase-2 Cancer Metastasis Rev 13 1994 241 256
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 241-256
    • Herschman, H.R.1
  • 19
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • D.A. Kujubu B.S. Fletcher B.C. Varnum TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue J Biol Chem 266 1991 12866 12872
    • (1991) J Biol Chem , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3
  • 20
    • 0027942421 scopus 로고
    • In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages
    • J.L. Masferrer S.T. Reddy B.S. Zweifel In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages J Pharm Exp Ther 270 1994 1340 1344
    • (1994) J Pharm Exp Ther , vol.270 , pp. 1340-1344
    • Masferrer, J.L.1    Reddy, S.T.2    Zweifel, B.S.3
  • 21
    • 0026548935 scopus 로고
    • Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme
    • J.L. Masferrer K. Seibert B.S. Zweifel Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme Proc Natl Acad Sci USA 89 1992 3917 3921
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3917-3921
    • Masferrer, J.L.1    Seibert, K.2    Zweifel, B.S.3
  • 22
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and non-ulcerogenic
    • J.L. Masferrer B. Zweifel S. Hauser Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and non-ulcerogenic Proc Natl Acad Sci USA 91 1994 3228 3232
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.2    Hauser, S.3
  • 23
    • 0025187588 scopus 로고
    • Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
    • J.L. Masferrer B.S. Zweifel K. Seibert Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice J Clin Invest 86 1990 1375 1379
    • (1990) J Clin Invest , vol.86 , pp. 1375-1379
    • Masferrer, J.L.1    Zweifel, B.S.2    Seibert, K.3
  • 24
    • 0027480087 scopus 로고
    • Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs
    • E.A. Meade W.L. Smith D.L. De Witt Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs J Biol Chem 268 1993 6610 6614
    • (1993) J Biol Chem , vol.268 , pp. 6610-6614
    • Meade, E.A.1    Smith, W.L.2    De Witt, D.L.3
  • 25
    • 0021274780 scopus 로고
    • Effect of dexamethasone on in vivo prostanoid production in the rabbit
    • A. Naray-Fejes-Toth G. Fejes-Toth C. Fischer Effect of dexamethasone on in vivo prostanoid production in the rabbit J Clin Invest 74 1984 120 123
    • (1984) J Clin Invest , vol.74 , pp. 120-123
    • Naray-Fejes-Toth, A.1    Fejes-Toth, G.2    Fischer, C.3
  • 26
    • 0021353248 scopus 로고
    • Plasma concentrations, renal excretion, and tissue release of prostaglandins in the rat with dexamethasone-induced hypertension
    • A. Nasjletti A. Erman L.M. Cagen Plasma concentrations, renal excretion, and tissue release of prostaglandins in the rat with dexamethasone-induced hypertension Endocrinology 114 1984 1033 1040
    • (1984) Endocrinology , vol.114 , pp. 1033-1040
    • Nasjletti, A.1    Erman, A.2    Cagen, L.M.3
  • 28
    • 0026322957 scopus 로고
    • A serum- and glucocorticoid-regulated 4 kilobase mRNA encodes a cyclooxygenase-related protein
    • M.K. O'Banion H.B. Sadowski V. Winn A serum- and glucocorticoid-regulated 4 kilobase mRNA encodes a cyclooxygenase-related protein J Biol Chem 266 1991 23261 23267
    • (1991) J Biol Chem , vol.266 , pp. 23261-23267
    • O'Banion, M.K.1    Sadowski, H.B.2    Winn, V.3
  • 29
    • 0001208476 scopus 로고
    • Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases
    • A. Raz A. Wyche P. Needleman Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases Proc Natl Acad Sci USA 86 1989 1657 1661
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1657-1661
    • Raz, A.1    Wyche, A.2    Needleman, P.3
  • 30
    • 0023513663 scopus 로고
    • Nonsteroidal anti-inflammatory drug gastropathy: Recognition and response
    • S.H. Roth R.E. Bennet Nonsteroidal anti-inflammatory drug gastropathy: Recognition and response Arch Intern Med 147 1987 2093 2100
    • (1987) Arch Intern Med , vol.147 , pp. 2093-2100
    • Roth, S.H.1    Bennet, R.E.2
  • 31
    • 0027944075 scopus 로고
    • Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
    • K. Seibert Y. Zhang K. Leahy Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain Proc Natl Acad Sci USA 91 1994 12013 12017
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12013-12017
    • Seibert, K.1    Zhang, Y.2    Leahy, K.3
  • 32
    • 0029162250 scopus 로고
    • Misoprostol reduced serious complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs
    • F.E. Silverstein D.Y. Graham J.R. Senior Misoprostol reduced serious complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs Ann Intern Med 123 1995 241 249
    • (1995) Ann Intern Med , vol.123 , pp. 241-249
    • Silverstein, F.E.1    Graham, D.Y.2    Senior, J.R.3
  • 33
    • 0028286337 scopus 로고
    • Actions and toxic effects of the nonsteroidal anti-inflammatory drugs
    • L.S. Simon Actions and toxic effects of the nonsteroidal anti-inflammatory drugs Curr Opin Rheumatol 6 1994 238 251
    • (1994) Curr Opin Rheumatol , vol.6 , pp. 238-251
    • Simon, L.S.1
  • 34
    • 0026744831 scopus 로고
    • Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles
    • J. Sirois J.S. Richards Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles J Biol Chem 267 1992 6382 6388
    • (1992) J Biol Chem , vol.267 , pp. 6382-6388
    • Sirois, J.1    Richards, J.S.2
  • 35
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • W. Xie J.G. Chipman D.L. Robertson Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing Proc Natl Acad Sci USA 88 1991 2692 2696
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.