Unitary behavior of skeletal, cardiac, and chimeric L-type Ca2+ channels expressed in dysgenic myotubes

Journal of General Physiology

Volumn 107, Issue 6, 1996, Pages 731-742

  Dirksen, Robert T ^a   Beam, Kurt G ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Dihydropyridine; Single channel recording; Skeletal muscle

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL; DIHYDROPYRIDINE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL MEMBRANE POTENTIAL; CHANNEL GATING; DEPOLARIZATION; HEART MUSCLE; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PROTEIN LOCALIZATION; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; TISSUE DISTRIBUTION;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANIMALS; BONE AND BONES; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CHIMERA; ELECTROPHYSIOLOGY; MICE; MICE, MUTANT STRAINS; MUSCLE, SKELETAL; MYOCARDIUM; REACTION TIME;

EID: 0029977282     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.107.6.731     Document Type: Article

References (31)

1. Adams, B.A., and K.G. Beam. 1989. A novel calcium current in dysgenic skeletal muscle. J. Gen. Physiol. 94:429-444.
2. Aldrich, R.W., D.P. Corey, and C.F. Stevens. 1983. A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature (Lond.). 306:436-441.
3. Beam, K.G., C.M. Knudson, and J.A. Powell. 1986. A lethal mutation in mice eliminates the slow calcium current in skeletal muscle cells. Nature (Lond.). 320:168-170.
4. Beam, K.G., and C.M. Knudson. 1988. Calcium currents in embryonic and neonatal mammalian skeletal muscle. J. Gen. Physiol. 91: 781-798.
5. Block, B.A., T. Imagawa, K.P. Campbell, and C. Franzini-Armstrong. 1988. Structural evidence for direct interaction between the molecular components of the transverse tubule/sarcoplasmic reticulum junction in skeletal muscle. J. Cell Biol. 107:2587-2600.
6. Caffrey, J.M. 1994. Kinetic properties of skeletal-muscle-like highthreshold calcium currents in a non-fusing muscle cell line. Pflügers Arch. Eur. J. Physiol. 427:277-288.
7. 2+ channels in guinea pig myocytes. Pflügers Arch. Eur. J. Physiol. 398:284-297.
8. Chaudhari, N. 1992. A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice. J. Biol. Chem. 267:25636-25639.
9. Chen, C., and P. Hess. 1990. Mechanism of gating of T-type calcium channels. J. Gen. Physiol. 96:603-630.
10. Dirksen, R.T., and K.G. Beam. 1995. Single calcium channel behavior in native skeletal muscle. J. Gen. Physiol. 105:227-247.
11. 3H]Nitrendipine receptors in skeletal muscle. Properties and preferential localization in transverse tubules. J. Biol. Chem. 258: 6086-6092.
12. García, J., T. Tanabe, and K.G. Beam. 1994. Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors. J. Gen. Physiol. 103:125-147.
13. Hamill, O.P., A. Marty, E. Neher, B. Sakmann, and F.J. Sigworth. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. Eur. J. Physiol. 391:85-100.
14. Hess, P., J.B. Lansman, and R.W. Tsien. 1984. Different modes of Ca channel gating behavior favoured by dihydropyridine Ca agonists and antagonists. Nature (Lond.). 311:538-544.
15. Hoshi, T., and S.J. Smith. 1987. Large depolarization induces long openings of voltage-dependent calcium channels in adrenal chromaffin cells. J. Neurosci. 7:571-580.
16. 2+ channel. Nature (Lond.). 352:527-530.
17. Ma, J., C. Mundiña-Weilenmann, M.M. Hosey, and E. Ríos. 1991. Dihydropyridine-sensitive skeletal muscle Ca channels in polarized planar bilayers. 1. Kinetics and voltage dependence of gating. Biophys. J. 60:890-901.
18. Marks, T.N., and S.W. Jones. 1992. Calcium currents in the A7r5 smooth muscle-derived cell line: an allosteric model for calcium channel activation and dihydropyridine agonist action. J. Gen. Physiol. 99:367-390.
19. Mikami, A., K. Imoto, T. Tanabe, T. Niidome, Y. Mori, H. Takeshima, S. Narumiya, and S. Numa. 1989. Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature (Lond.). 340:230-233.
20. Nakai, J., B.A. Adams, K. Imoto, and K.G. Beam. 1994. Critical roles of the S3 segment and the S3-S4 linker of repeat I in activation of L-type calcium channels. 1994. Proc. Natl. Acad. Sci. USA. 91: 1014-1018.
21. Neher, E., and C.F. Stevens. 1977. Conductance fluctuations and ionic pores in membranes. Annu. Rev. Biophys. Bioeng. 6:345-381.
22. Norman, R.I., M. Borsotto, M. Fosset, and M. Lazdunski. 1983. Biochem. Biophy. Res. Commun. 111:878-883.
23. Patlak, J.B. 1993. Measuring kinetics of complex ion channel data using mean-variance histograms. Biophys. J. 65:29-49.
24. 1-subunit of the dihydropyridine receptor from skeletal muscle. Nature (Lond.). 340:233-236.
25. Sun, X.H., F. Protasi, M. Takahashi, H. Takeshima, D.G. Ferguson, and C. Franzini-Armstrong. 1995. Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle. J. Cell Biol. 129:659-671.
26. Takekura, H., L. Bennett, T. Tanabe, K.G. Beam, and C. Franzini-Armstrong. 1994. Restoration of junctional tetrads in dysgenic myotubes by dihydropyridine receptor cDNA. Biophys. J. 67:793-803.
27. Tanabe, T., K.G. Beam, J.A. Powell, and S. Numa. 1988. Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA. Nature (Lond.). 336:134-139.
28. Tanabe, T., A. Mikami, S. Numa, and K.G. Beam. 1990. Cardiactype excitation-contraction coupling in dysgenic muscle injected with cardiac dihydropyridine receptor cDNA. Nature (Lond.). 344: 451-453.
29. Tanabe, T., B.A. Adams, S. Numa, and K.G. Beam. 1991. Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics. Nature (Lond.). 352:800-803.
30. + channels of bovine chromaffin cells. J. Gen. Physiol. 84:157-186.
31. Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1994. Shaker potassium channel gating: evaluation of kinetic models for activation. J. Gen. Physiol. 103:321-362.