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Volumn 53, Issue 3, 1996, Pages 176-184

Maternal phenylketonuria: A metabolic teratogen

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE;

EID: 0029977276     PISSN: 00403709     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9926(199603)53:3<176::AID-TERA5>3.0.CO;2-2     Document Type: Article
Times cited : (96)

References (59)
  • 1
    • 0004438952 scopus 로고
    • Maternal phenylketonuria and foetal brain damage: An attempt at prevention by dietary control
    • K.S. Holt and V.P. Coffey, eds. E.&S. Livingstone, Edinburgh
    • Allan, J.D., and Brown, J.K. (1968) Maternal phenylketonuria and foetal brain damage: An attempt at prevention by dietary control. In: Some Recent Advances in Inborn Errors of Metabolism. K.S. Holt and V.P. Coffey, eds. E.&S. Livingstone, Edinburgh, pp. 14-36.
    • (1968) Some Recent Advances in Inborn Errors of Metabolism , pp. 14-36
    • Allan, J.D.1    Brown, J.K.2
  • 2
    • 0023846311 scopus 로고
    • hph-1:A mouse mutant with hereditary hyperphenylalaninemia induced by ethylnitrosourea mutagenesis
    • Bode, V.C., J.D. McDonald, J.-L. Guenet, and D. Simon (1988) hph-1:A mouse mutant with hereditary hyperphenylalaninemia induced by ethylnitrosourea mutagenesis. Genetics, 118:299-305.
    • (1988) Genetics , vol.118 , pp. 299-305
    • Bode, V.C.1    McDonald, J.D.2    Guenet, J.-L.3    Simon, D.4
  • 3
    • 0016008186 scopus 로고
    • Deux enfants nés de mère phénylcétonurique echec d'un régime pauvre en phénylalanine institué pendant la deuxième grossesse
    • Bovier-Lapierre, M., C. Saint-Dizier, F. Freycon, M. David, C. Dorche, and M. Jeune (1974) Deux enfants nés de mère phénylcétonurique echec d'un régime pauvre en phénylalanine institué pendant la deuxième grossesse. Pediatrie, 29:51-72.
    • (1974) Pediatrie , vol.29 , pp. 51-72
    • Bovier-Lapierre, M.1    Saint-Dizier, C.2    Freycon, F.3    David, M.4    Dorche, C.5    Jeune, M.6
  • 4
    • 2842522581 scopus 로고
    • Blood-tissue movement of amino acids in various organs: The basolateral membrane and its importance in polarity of transepithelial transport
    • D.L. Yudilevich and C.A.R. Boyd, eds. Manchester University Press, Manchester
    • Boyd, C.A.R., and D.L. Yudilevich (1987) Blood-tissue movement of amino acids in various organs: the basolateral membrane and its importance in polarity of transepithelial transport. In: Amino Acid Transport in Animal Cells. D.L. Yudilevich and C.A.R. Boyd, eds. Manchester University Press, Manchester, pp. 120-156.
    • (1987) Amino Acid Transport in Animal Cells , pp. 120-156
    • Boyd, C.A.R.1    Yudilevich, D.L.2
  • 5
    • 0029278219 scopus 로고
    • Difficulties in the prenatal diagnosis of microcephaly
    • Bromley, B., and B.R. Benacerraf (1995) Difficulties in the prenatal diagnosis of microcephaly. J. Ultrasound Med., 14:303-306.
    • (1995) J. Ultrasound Med. , vol.14 , pp. 303-306
    • Bromley, B.1    Benacerraf, B.R.2
  • 6
    • 0021755711 scopus 로고
    • Effects of untreated maternal phenylketonuria and hyperphenylalaninemia in the fetus
    • Buist, N.R.M., J. Tuerck, E. Lis, and R. Penn (1984) Effects of untreated maternal phenylketonuria and hyperphenylalaninemia in the fetus. N. Engl. J. Med., 311:52-53.
    • (1984) N. Engl. J. Med. , vol.311 , pp. 52-53
    • Buist, N.R.M.1    Tuerck, J.2    Lis, E.3    Penn, R.4
  • 7
    • 0014937986 scopus 로고
    • Learning impairment associated with maternal phenylketonuria in rats
    • Butcher, R.E. (1970) Learning impairment associated with maternal phenylketonuria in rats. Nature, 226:555-556.
    • (1970) Nature , vol.226 , pp. 555-556
    • Butcher, R.E.1
  • 8
    • 0017877998 scopus 로고
    • Comparison of α-methylphenylalanine and p-chlorophenylalanine as inducers of chronic hyperphenylalaninaemia in developing rats
    • Delvalle, J.A., G. Dienel, and O. Greengard (1978) Comparison of α-methylphenylalanine and p-chlorophenylalanine as inducers of chronic hyperphenylalaninaemia in developing rats. Biochem. J., 170:449-459.
    • (1978) Biochem. J. , vol.170 , pp. 449-459
    • Delvalle, J.A.1    Dienel, G.2    Greengard, O.3
  • 9
    • 0025172172 scopus 로고
    • Phenylalanine and its metabolites induce embryopathies in mouse embryos in culture
    • Denno, K.M., and T.W. Sadler (1990) Phenylalanine and its metabolites induce embryopathies in mouse embryos in culture. Teratology, 42:565-570.
    • (1990) Teratology , vol.42 , pp. 565-570
    • Denno, K.M.1    Sadler, T.W.2
  • 10
    • 0027212536 scopus 로고
    • Phenylpyruvate, fetal damage, and maternal phenylketonuria syndrome
    • Dorland, L., B.T. Poll-The, M. Duran, J.A.M. Smeitink, and R. Berger (1993). Phenylpyruvate, fetal damage, and maternal phenylketonuria syndrome. Lancet, 341:1351-1352.
    • (1993) Lancet , vol.341 , pp. 1351-1352
    • Dorland, L.1    Poll-The, B.T.2    Duran, M.3    Smeitink, J.A.M.4    Berger, R.5
  • 11
    • 0023640629 scopus 로고
    • Timing of strict diet in relation to fetal damage in maternal phenylketonuria
    • Drogari, E., I. Smith, M. Beasley, and J.K. Lloyd (1987) Timing of strict diet in relation to fetal damage in maternal phenylketonuria. Lancet, 2:927-930.
    • (1987) Lancet , vol.2 , pp. 927-930
    • Drogari, E.1    Smith, I.2    Beasley, M.3    Lloyd, J.K.4
  • 12
    • 15844423784 scopus 로고
    • Mechanisms of hypomyelination and gliosis in a genetic mouse model for phenylketonuria
    • abst.
    • Dyer, C.A., T. Philibotte, H. Levy, and J. Cruz (1995) Mechanisms of hypomyelination and gliosis in a genetic mouse model for phenylketonuria. J. Neurochem., 64 (suppl):S111 (abst.).
    • (1995) J. Neurochem. , vol.64 , Issue.SUPPL.
    • Dyer, C.A.1    Philibotte, T.2    Levy, H.3    Cruz, J.4
  • 13
    • 0013921831 scopus 로고
    • Prenatal and postnatal developmental consequences of maternal phenylketonuria
    • Fisch, R.O., W.A. Walker, and J.A. Anderson (1966) Prenatal and postnatal developmental consequences of maternal phenylketonuria. Pediatrics, 37:979-986.
    • (1966) Pediatrics , vol.37 , pp. 979-986
    • Fisch, R.O.1    Walker, W.A.2    Anderson, J.A.3
  • 14
    • 84941432771 scopus 로고
    • Über Ausscheidung von Phenylbrenztraubensäure in den Harn als Stoffwechselanomalie in Verbindung mit Imbezillitäte, Hoppe-Seylers Z
    • Foiling, A. (1934) Über Ausscheidung von Phenylbrenztraubensäure in den Harn als Stoffwechselanomalie in Verbindung mit Imbezillitäte, Hoppe-Seylers Z. Physiol. Chem., 227:169-176.
    • (1934) Physiol. Chem. , vol.227 , pp. 169-176
    • Foiling, A.1
  • 15
    • 0022899150 scopus 로고
    • Prevention of fetal damage through dietary control of maternal hyperphenylalaninemia
    • Ghavami, M., H.L. Levy, and R.W. Erbe (1986) Prevention of fetal damage through dietary control of maternal hyperphenylalaninemia. Clin. Obstet. Gynecol., 29:580-585.
    • (1986) Clin. Obstet. Gynecol. , vol.29 , pp. 580-585
    • Ghavami, M.1    Levy, H.L.2    Erbe, R.W.3
  • 16
    • 0027177691 scopus 로고
    • Molecular analysis of phenylketonuria in Denmark: 99% of the mutations detected by denaturing gradient gel electrophoresis
    • Guldberg, P., K.F. Henriksen, and F. Guttler (1993) Molecular analysis of phenylketonuria in Denmark: 99% of the mutations detected by denaturing gradient gel electrophoresis. Genomics, 17:141-146.
    • (1993) Genomics , vol.17 , pp. 141-146
    • Guldberg, P.1    Henriksen, K.F.2    Guttler, F.3
  • 17
    • 75449123150 scopus 로고
    • A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants
    • Guthrie, R., and A. Susi (1963) A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants. Pediatrics, 32:338-343.
    • (1963) Pediatrics , vol.32 , pp. 338-343
    • Guthrie, R.1    Susi, A.2
  • 18
    • 0038059648 scopus 로고
    • Embryotoxicity of phenylketonuria (PKU)-related metabolites of phenylalanine (phe) is rat whole embryo culture
    • abst..
    • Hamers, A.E.P., A.H. Piersma, A. Verhoef, E.J.H.M. Jansen, and P.W.J. Peters (1989) Embryotoxicity of phenylketonuria (PKU)-related metabolites of phenylalanine (phe) is rat whole embryo culture. Teratology, 40:284 (abst.).
    • (1989) Teratology , vol.40 , pp. 284
    • Hamers, A.E.P.1    Piersma, A.H.2    Verhoef, A.3    Jansen, E.J.H.M.4    Peters, P.W.J.5
  • 20
    • 0021823488 scopus 로고
    • Effects of hyperphenylalaninemia in the fetal stage on the postnatal development of fetal rat brain
    • Hirano, S., Y. Takagi, T. Kanamatsu, and K. Nakai (1985) Effects of hyperphenylalaninemia in the fetal stage on the postnatal development of fetal rat brain. Neurochem Res., 10:1071-1081.
    • (1985) Neurochem Res. , vol.10 , pp. 1071-1081
    • Hirano, S.1    Takagi, Y.2    Kanamatsu, T.3    Nakai, K.4
  • 21
    • 0001577381 scopus 로고
    • Phenylpyruvic oligophrenia. Deficiency of phenyl-alanine-oxidizing system
    • Jervis, G.A. (1953) Phenylpyruvic oligophrenia. Deficiency of phenyl-alanine-oxidizing system. Proc. Soc. Exp. Biol. Med., 52:514-515.
    • (1953) Proc. Soc. Exp. Biol. Med. , vol.52 , pp. 514-515
    • Jervis, G.A.1
  • 22
    • 0043084226 scopus 로고
    • Chemical and metabolic studies on phenylalanine. II. The phenylalanine content of the blood and spinal fluid in phenylpyruvic oligophrenia
    • Jervis, G.A., R.J. Block, D. Boiling, and E. Kanze (1940) Chemical and metabolic studies on phenylalanine. II. The phenylalanine content of the blood and spinal fluid in phenylpyruvic oligophrenia. J. Biol. Chem., 134:105-113.
    • (1940) J. Biol. Chem. , vol.134 , pp. 105-113
    • Jervis, G.A.1    Block, R.J.2    Boiling, D.3    Kanze, E.4
  • 23
    • 0014313137 scopus 로고
    • "Fetal PKU": The effect of maternal hyperphenylalaninemia during pregnancy in the rhesus monkey (Macaca mulatta)
    • Kerr, G.R., A.S. Chamove, H.F. Harlow, and H.A. Waisman (1968) "Fetal PKU": The effect of maternal hyperphenylalaninemia during pregnancy in the rhesus monkey (Macaca mulatta). Pediatrics, 42:27-36.
    • (1968) Pediatrics , vol.42 , pp. 27-36
    • Kerr, G.R.1    Chamove, A.S.2    Harlow, H.F.3    Waisman, H.A.4
  • 24
    • 0021770948 scopus 로고
    • More on untreated maternal hyperphenylalaninemia
    • Kirkman, H.N., and R.E. Hicks (1984) More on untreated maternal hyperphenylalaninemia. N. Engl. J. Med., 311:1125-1126.
    • (1984) N. Engl. J. Med. , vol.311 , pp. 1125-1126
    • Kirkman, H.N.1    Hicks, R.E.2
  • 25
    • 0027442890 scopus 로고
    • The North American Collaborative Study of Maternal Phenylketonuria: Status report 1993
    • Koch, R., H.L. Levy, R. Matalon, B. Rouse, W. Hanley, and C. Agen (1993) The North American Collaborative Study of Maternal Phenylketonuria: Status report 1993. Am. J. Dis. Child., 147:1224-1230.
    • (1993) Am. J. Dis. Child. , vol.147 , pp. 1224-1230
    • Koch, R.1    Levy, H.L.2    Matalon, R.3    Rouse, B.4    Hanley, W.5    Agen, C.6
  • 26
    • 0025083324 scopus 로고
    • Transport of amino acids by the human placenta: Predicted effects thereon of maternal hyperphenylalaninaemia
    • Kudo, Y., and C.A.R. Boyd (1990) Transport of amino acids by the human placenta: Predicted effects thereon of maternal hyperphenylalaninaemia. J. Inher. Metab. Dis., 13:617-626.
    • (1990) J. Inher. Metab. Dis. , vol.13 , pp. 617-626
    • Kudo, Y.1    Boyd, C.A.R.2
  • 27
    • 0019156116 scopus 로고
    • Maternal phenylketonuria and hyperphenylalaninemia. An international survey of the outcome of untreated and treated pregnancies
    • Lenke, R.R., and H.L. Levy (1980) Maternal phenylketonuria and hyperphenylalaninemia. An international survey of the outcome of untreated and treated pregnancies. N. Engl. J. Med., 303:1202-1208.
    • (1980) N. Engl. J. Med. , vol.303 , pp. 1202-1208
    • Lenke, R.R.1    Levy, H.L.2
  • 28
    • 0020042554 scopus 로고
    • Maternal phenylketonuria - Results of dietary therapy
    • Lenke, R.R., and H.L. Levy (1982) Maternal phenylketonuria - Results of dietary therapy. Am. J. Obstet. Gynecol., 142:548-553.
    • (1982) Am. J. Obstet. Gynecol. , vol.142 , pp. 548-553
    • Lenke, R.R.1    Levy, H.L.2
  • 29
    • 0041530905 scopus 로고
    • Reproductive effects of inborn errors of metabolism
    • J.-P. Farriaux and J.-L. Dhondt, eds. Elsevier, Amsterdam
    • Levy, H.L. (1994) Reproductive effects of inborn errors of metabolism. In: New Horizons in Neonatal Screening. J.-P. Farriaux and J.-L. Dhondt, eds. Elsevier, Amsterdam, pp. 61-68.
    • (1994) New Horizons in Neonatal Screening , pp. 61-68
    • Levy, H.L.1
  • 30
    • 0027938873 scopus 로고
    • Current approaches to genetic metabolic screening in newborns
    • Levy, H.L., and A.S. Cornier (1994) Current approaches to genetic metabolic screening in newborns. Curr. Opin. Pediatr., 6:707-711.
    • (1994) Curr. Opin. Pediatr. , vol.6 , pp. 707-711
    • Levy, H.L.1    Cornier, A.S.2
  • 32
    • 0021355707 scopus 로고
    • Lack of fetal effect on blood phenylalanine concentration in maternal phenylketonuria
    • Levy, H.L., R.R. Lenke, and R. Koch (1984) Lack of fetal effect on blood phenylalanine concentration in maternal phenylketonuria. J. Pediatr., 104:245-247.
    • (1984) J. Pediatr. , vol.104 , pp. 245-247
    • Levy, H.L.1    Lenke, R.R.2    Koch, R.3
  • 35
    • 15844421898 scopus 로고
    • Tissue amino acids and organic acids in the maternal phenylketonuria (MPKU) fetus: Implications for the pathogenesis of fetal damage in MPKU
    • abst.
    • Levy, H.L., E.W. Naylor, and P. Mamunes (1988) Tissue amino acids and organic acids in the maternal phenylketonuria (MPKU) fetus: implications for the pathogenesis of fetal damage in MPKU. Am. J. Hum. Genet., 43:A12 (abst.).
    • (1988) Am. J. Hum. Genet. , vol.43
    • Levy, H.L.1    Naylor, E.W.2    Mamunes, P.3
  • 36
    • 0021040495 scopus 로고
    • Effects of untreated maternal phenylketonuria and hyperphenylalaninemia in the fetus
    • Levy, H.L., and S.E. Waisbren (1983) Effects of untreated maternal phenylketonuria and hyperphenylalaninemia in the fetus. N. Engl. J. Med., 309:1269-1274.
    • (1983) N. Engl. J. Med. , vol.309 , pp. 1269-1274
    • Levy, H.L.1    Waisbren, S.E.2
  • 37
    • 0028643633 scopus 로고
    • PKU in adolescents: Rationale and psychosocial factors in diet continuation
    • Levy, H.L., and S.E. Waisbren (1994a) PKU in adolescents: rationale and psychosocial factors in diet continuation. Acta Paediatr. Suppl., 407:92-97.
    • (1994) Acta Paediatr. Suppl. , vol.407 , pp. 92-97
    • Levy, H.L.1    Waisbren, S.E.2
  • 40
    • 0014202358 scopus 로고
    • Chlorophenylalanine-induced chemical manifestations of phenylketonuria in rats
    • Lipton, M.A., R. Gordon, G. Guroff, and S. Udenfriend (1967) p-Chlorophenylalanine-induced chemical manifestations of phenylketonuria in rats. Science, 156:248-250.
    • (1967) Science , vol.156 , pp. 248-250
    • Lipton, M.A.1    Gordon, R.2    Guroff, G.3    Udenfriend, S.4
  • 42
    • 0016298411 scopus 로고
    • Admissions of phenylketonuric patients to residential institutions before and after screening programs of the newborn infant
    • MacCready, R.A. (1974) Admissions of phenylketonuric patients to residential institutions before and after screening programs of the newborn infant. J. Pediatr., 85:383-385.
    • (1974) J. Pediatr. , vol.85 , pp. 383-385
    • MacCready, R.A.1
  • 44
    • 0015029234 scopus 로고
    • Congenital heart disease in 56,109 births: Incidence and natural history
    • Mitchell, S.C., S.B. Korones, and H.W. Berendes (1971) Congenital heart disease in 56,109 births: Incidence and natural history. Circulation, 43:323-332.
    • (1971) Circulation , vol.43 , pp. 323-332
    • Mitchell, S.C.1    Korones, S.B.2    Berendes, H.W.3
  • 45
    • 0022569554 scopus 로고
    • Effects of phenylalanine loading on protein synthesis in the fetal heart and brain of rat: An experimental approach to maternal phenylketonuria
    • Okano, Y., I.Z. Chow, G. Isshiki, A. Inoue, and T. Oura (1986) Effects of phenylalanine loading on protein synthesis in the fetal heart and brain of rat: an experimental approach to maternal phenylketonuria. J. Inher. Metab. Dis., 9:15-24.
    • (1986) J. Inher. Metab. Dis. , vol.9 , pp. 15-24
    • Okano, Y.1    Chow, I.Z.2    Isshiki, G.3    Inoue, A.4    Oura, T.5
  • 46
    • 0023002384 scopus 로고
    • The safety of aspartame
    • Pardridge, W.M. (1986) The safety of aspartame. J.A.M.A., 256:2678.
    • (1986) J.A.M.A. , vol.256 , pp. 2678
    • Pardridge, W.M.1
  • 48
    • 0020174415 scopus 로고
    • Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA
    • Robson, K.J.H., T. Chandra, R.T.A. MacGillivray, and S.L.C. Woo (1982) Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA. Proc. Natl. Acad. Sci. U.S.A., 79:4701-4705.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 4701-4705
    • Robson, K.J.H.1    Chandra, T.2    MacGillivray, R.T.A.3    Woo, S.L.C.4
  • 49
    • 0023132625 scopus 로고
    • New England Maternal PKU Project: Prospective study of untreated and treated pregnancies and their outcomes
    • Rohr, F.J., L.B. Doherty, S.E. Waisbren, I.V. Bailey, M.E. Ampola, B. Benacerraf, and H.L. Levy (1987) New England Maternal PKU Project: Prospective study of untreated and treated pregnancies and their outcomes. J. Pediatr., 110:391-398.
    • (1987) J. Pediatr. , vol.110 , pp. 391-398
    • Rohr, F.J.1    Doherty, L.B.2    Waisbren, S.E.3    Bailey, I.V.4    Ampola, M.E.5    Benacerraf, B.6    Levy, H.L.7
  • 52
    • 0023680924 scopus 로고
    • The effects of maternal hyperphenylalaninemia on learning in mature rats
    • Sadava, D., and D. Sutcliffe (1988) The effects of maternal hyperphenylalaninemia on learning in mature rats. Life Sci., 43:1119-1123.
    • (1988) Life Sci. , vol.43 , pp. 1119-1123
    • Sadava, D.1    Sutcliffe, D.2
  • 53
    • 0028243835 scopus 로고
    • Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term
    • Schoonheyt, W.E., J.T.R. Clarke, W.B. Hanley, J.M. Johnson, and D.C. Lehotay (1994) Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term. Clin. Chim. Acta, 225:165-169.
    • (1994) Clin. Chim. Acta , vol.225 , pp. 165-169
    • Schoonheyt, W.E.1    Clarke, J.T.R.2    Hanley, W.B.3    Johnson, J.M.4    Lehotay, D.C.5
  • 55
    • 0020662576 scopus 로고
    • Effects of maternal hyperphenylalaninemia on fetal brain development: A morphological study
    • Spero, D.A., and M.C. Yu (1983) Effects of maternal hyperphenylalaninemia on fetal brain development: A morphological study. Exp. Neurol., 79:655-665.
    • (1983) Exp. Neurol. , vol.79 , pp. 655-665
    • Spero, D.A.1    Yu, M.C.2
  • 56
    • 0027512975 scopus 로고
    • Prenatal alcohol exposure and long-term developmental consequences
    • Spohr, H.-L., J. Willms, and H.-Ch. Steinhausen (1993) Prenatal alcohol exposure and long-term developmental consequences. Lancet, 341:907-910.
    • (1993) Lancet , vol.341 , pp. 907-910
    • Spohr, H.-L.1    Willms, J.2    Steinhausen, H.-Ch.3
  • 58
    • 0025801690 scopus 로고
    • Psychosocial factors is maternal phenylketonuria: Prevention of unplanned pregnancies
    • Waisbren, S.E., S. Shiloh, P. St. James, and H.L. Levy (1991) Psychosocial factors is maternal phenylketonuria: Prevention of unplanned pregnancies. Am J Public Health 81:299-304.
    • (1991) Am J Public Health , vol.81 , pp. 299-304
    • Waisbren, S.E.1    Shiloh, S.2    St. James, P.3    Levy, H.L.4
  • 59
    • 0029619287 scopus 로고
    • Psychosocial factors in maternal phenylketonuria: Women's adherence to medical recommendations
    • Waisbren, S.E., B.D. Hamilton, P.J. St. James, S. Shiloh, and H.L. Levy (1995) Psychosocial factors in maternal phenylketonuria: Women's adherence to medical recommendations. Am. J. Public Health, 85:1636-1644.
    • (1995) Am. J. Public Health , vol.85 , pp. 1636-1644
    • Waisbren, S.E.1    Hamilton, B.D.2    St. James, P.J.3    Shiloh, S.4    Levy, H.L.5


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