Serum levels of hepatitis C virus core protein in patients with chronic hepatitis C treated with interferon alfa

Hepatology

Volumn 23, Issue 6, 1996, Pages 1330-1333

  Tanaka, Eiji ^a   Kiyosawa, Kendo ^a   Matsumoto, Akihiro ^a   Kashiwakuma, Tomiko ^b   Hasegawa, Akira ^b   Mori, Hlroyuki ^c   Yanagihara, Osamu ^c   Ohta, Yohsuke ^c  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Tonen Corporation   (Japan)

^c International Reagents Corporation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CORE PROTEIN; HEPATITIS ANTIGEN; HEPATITIS C ANTIBODY; RECOMBINANT ALPHA2A INTERFERON; VIRUS RNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIBODY DETECTION; ANTIGEN DETECTION; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CLINICAL FEATURE; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENCE; HEPATITIS C; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; LIVER BIOPSY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RNA ANALYSIS;

EID: 0029977260     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v23.pm0008675147     Document Type: Article

References (18)

1. Alter HJ, Purcell RH, Shin JW, Melpolder JC, Moughton M, Choo QL, Kuo G. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 1989;321:1494-1500.
2. Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa K, Nakano Y, Furuta S, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. HEPATOLOGY 1990; 12:671-675.
3. Davis GL, Balart LA, Shiff ER, Lindsay K, Bodenheimer HC, Perrillo RP, Garey W, et al. Treatment of chronic hepatitis C with recombinant Interferon alfa. N Engl J Med 1989;321:1501-1506.
4. Di Bisceglie AM, Martin P, Kassianides C, Lisker-Melman M, Murray L, Waggoner J, Goodman Z, et al. Recombinant interferon alfa therapy for chronic hepatitis C: a randomized, double-blind, placebo-controlled trial. N Engl J Med 1989;321:1506-1510.
5. Matsumoto A, Tanaka E, Suzuki T, Ogata H, Kiyosawa K. Viral and host factors that contribute to the efficacy of interferon-alpha 2a therapy in patients with chronic hepatitis C. Dig Dis Sci 1994;39:1273-1280.
6. Lau JYN, Davis GL, Kniffen J, Qian PK, Urdea MS, Chan CS, Masashi M, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993;341:1501-1504.
7. Suzuki T, Tanaka E, Matsumoto A, Urushihara A, Sodeyama T. Usefulness of simple assays for serum concentration of hepatitis C virus (HCV) RNA and HCV genotype in predicting response of patients with chronic hepatitis C to interferon α2a therapy. J Med Virol 1995;46:162-168.
8. Tanaka T, Lau JYN, Mizokami M, Orito E, Tanaka E, Kiyosawa K, Yasui K, et al. Simple fluorescent enzyme immunoassay for detection and quantification of hepatitis C viremia. J Hepatol 1995;23:742-745.
9. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. HEPATOLOGY 1994;19:1513-1520.
10. Kwork S, Higuti R. Avoiding false positives with PCR. Nature 1989;339:237-238.
11. Saito M, Hasegawa A, Kashiwakuma T, Kohara M, Sugi M, Miki K, Yamamoto T, et al. Performance of an enzyme-linked immunosorbent assay system for antibodies to hepatitis C virus with two new antigens (c11/c7). Clin Chem 1992;38:2434-2439.
12. Tsukiyama-Kohara K, Yamaguchi K, Maki N, Ohta Y, Miki K, Mizokami M, Kohara M. Antigenicities of group 1 and 2 hepatitis C virus polypeptides: molecular basis of diagnosis. Virology 1993; 192:430-437.
13. Tanaka T, Tsukiyama-Kohara K, Yamaguchi K, Yagi S, Tanaka S, Hasegawa A, Ohta Y, et al. Significance of specific antibody assay for genotyping of hepatitis C virus. HEPATOLOGY 1994;19: 1347-1353.
14. Tanaka E, Kiyosawa K, Matsushima T, Ishikawa K, Hino K, Tanaka S, Nose H, et al. Epidemiology of genotypes of hepatitis C virus in Japanese patients with type C chronic liver diseases: a multi-institution analysis. J Gastroenterol Hepatol 1995;10: 538-545.
15. Simmonds P, Alberti A, Alter HJ, Bonino F, Bradley DW, Brechot C, Brouwer JT, et al. A proposed system for the nomenclature of hepatitis C viral genotypes. HEPATOLOGY 1994;19: 1321-1324.
16. Kohara M, Tanaka T, Tsukiyama-Kohara K, Tanaka S, Mizokami M, Lau JYN, Hattori N. Hepatitis C virus genotypes 1 and 2 respond to interferon-α with different virologic kinetics. J Infect Dis 1995;172:934-938.
17. Shindo M, Di Bisceglie AM, Cheung L, Shih WK, Cristiano K, Feinstone SM, Hoofnagle JH. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C. Ann Intern Med 1991;115:700-704.
18. Lau JYN, Mizokami M, Ohno T, Diamond DA, Kniffen J, Davis GL. Discrepancy between biochemical and virological responses to interferon-α in chronic hepatitis C. Lancet 1993;342:1208-1209.