-
1
-
-
0025742993
-
Dose- and time-dependent effect of an acute 2-amino-1,2,4-triazole injection on rat brain catalase activity
-
ARAGON CM, ROGAN F AND AMIT Z. (1991). Dose- and time-dependent effect of an acute 2-amino-1,2,4-triazole injection on rat brain catalase activity. Biochem. Pharmacol., 42, 699-702.
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 699-702
-
-
Aragon, C.M.1
Rogan, F.2
Amit, Z.3
-
2
-
-
0021881114
-
Ifosfamide pharmacology, safety and therapeutic potential
-
BRADE WP, HERDRICH K AND VARINI M. (1985). Ifosfamide pharmacology, safety and therapeutic potential. Cancer Treat. Rev., 12, 1-47.
-
(1985)
Cancer Treat. Rev.
, vol.12
, pp. 1-47
-
-
Brade, W.P.1
Herdrich, K.2
Varini, M.3
-
3
-
-
0022486199
-
Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity
-
CAVALLETTI E, TOFANETTI O AND ZUNINO F. (1986). Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity. Cancer Lett., 32, 1-6.
-
(1986)
Cancer Lett.
, vol.32
, pp. 1-6
-
-
Cavalletti, E.1
Tofanetti, O.2
Zunino, F.3
-
4
-
-
0017227825
-
Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde
-
CEDERBAUM AI AND RUBIN E. (1976). Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde. Biochem. Pharmacol., 25, 963-973.
-
(1976)
Biochem. Pharmacol.
, vol.25
, pp. 963-973
-
-
Cederbaum, A.I.1
Rubin, E.2
-
6
-
-
0022541787
-
Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: Studies with N-acetyl-D-cysteine in mice
-
CORCORAN GB AND WONG BK. (1986). Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: Studies with N-acetyl-D-cysteine in mice. J. Pharmacol. Exp. Ther., 238, 54-61.
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.238
, pp. 54-61
-
-
Corcoran, G.B.1
Wong, B.K.2
-
7
-
-
0018749594
-
Cyclophosphamide cystitis identification of acrolein as a causative agent
-
COX PJ. (1979). Cyclophosphamide cystitis identification of acrolein as a causative agent. Biochem. Pharmacol., 28, 2045-2049.
-
(1979)
Biochem. Pharmacol.
, vol.28
, pp. 2045-2049
-
-
Cox, P.J.1
-
8
-
-
77957179532
-
Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in the male B6C3F1 mouse
-
DANIEL FB, DE ANGELO AB, STOBER JA, OLSON GR AND PAGE NP. (1992). Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in the male B6C3F1 mouse. Fund. Appl. Toxicol., 19, 159-168.
-
(1992)
Fund. Appl. Toxicol.
, vol.19
, pp. 159-168
-
-
Daniel, F.B.1
De Angelo, A.B.2
Stober, J.A.3
Olson, G.R.4
Page, N.P.5
-
9
-
-
0022499357
-
Differential inhibition of rat tissue catalase by cyanamide
-
DEMASTER EG, REDFERN B, SHIROTA FN AND NAGASAWA HT. (1986). Differential inhibition of rat tissue catalase by cyanamide. Biochem. Pharmacol., 35, 2081-2085.
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 2081-2085
-
-
Demaster, E.G.1
Redfern, B.2
Shirota, F.N.3
Nagasawa, H.T.4
-
10
-
-
3042934967
-
Tissue sulfhydryl groups
-
ELLMAN GL. (1959). Tissue sulfhydryl groups. Arch. Biochem. Biophys., 82, 70-77.
-
(1959)
Arch. Biochem. Biophys.
, vol.82
, pp. 70-77
-
-
Ellman, G.L.1
-
11
-
-
0028222128
-
Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration
-
FORKERT PG, REDZA ZM, MANGOS S, PARK SS AND TAM S-P. (1994). Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration. Drug Metabol. Disp., 22, 248-253.
-
(1994)
Drug Metabol. Disp.
, vol.22
, pp. 248-253
-
-
Forkert, P.G.1
Redza, Z.M.2
Mangos, S.3
Park, S.S.4
Tam, S.-P.5
-
12
-
-
0023912974
-
Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors
-
GIERON MA, BARAK LS AND ESTRADA J. (1988). Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors. J. Neuro-Oncol., 6, 29-30.
-
(1988)
J. Neuro-Oncol.
, vol.6
, pp. 29-30
-
-
Gieron, M.A.1
Barak, L.S.2
Estrada, J.3
-
13
-
-
0023035082
-
Dechloroethylation of ifosfamide and neurotoxicity
-
GOREN MP, WRIGHT RK, PRATT CB AND PELL FE. (1986). Dechloroethylation of ifosfamide and neurotoxicity. Lancet, 2, 1219-1220.
-
(1986)
Lancet
, vol.2
, pp. 1219-1220
-
-
Goren, M.P.1
Wright, R.K.2
Pratt, C.B.3
Pell, F.E.4
-
14
-
-
0345654274
-
Glutathione: Interorgan translocation, turnover, and metabolism
-
GRIFFITH OW AND MEISTER A. (1979). Glutathione: Interorgan translocation, turnover, and metabolism. Proc. Natl Acad. Sci. USA, 76, 5606-5610.
-
(1979)
Proc. Natl Acad. Sci. USA
, vol.76
, pp. 5606-5610
-
-
Griffith, O.W.1
Meister, A.2
-
15
-
-
0019514883
-
Changes in glutathione in acute and chronic alcohol intoxication
-
GUERRI C AND GRISOLIA S. (1980). Changes in glutathione in acute and chronic alcohol intoxication. Pharmacol. Biochem. Behav., 13, 53-61.
-
(1980)
Pharmacol. Biochem. Behav.
, vol.13
, pp. 53-61
-
-
Guerri, C.1
Grisolia, S.2
-
16
-
-
0020680491
-
The alcohol dehydrogenase gene complex on chromosome 3 of the mouse
-
Rattazzi MC, Scandalios JG, Whit GS (eds) Alan R Liss: New York
-
HOLMES RS, DULEY JA AND BURNELL JN. (1983). The alcohol dehydrogenase gene complex on chromosome 3 of the mouse. In Isozymes, Current Topics in Biological and Medical Research, Rattazzi MC, Scandalios JG, Whit GS (eds) pp. 155-174. Alan R Liss: New York.
-
(1983)
Isozymes, Current Topics in Biological and Medical Research
, pp. 155-174
-
-
Holmes, R.S.1
Duley, J.A.2
Burnell, J.N.3
-
17
-
-
0006853058
-
Metabolism of 2-chloroethanol in the rat
-
JOHNSON MK. (1967). Metabolism of 2-chloroethanol in the rat. Biochem. Pharmacol., 16, 185-199.
-
(1967)
Biochem. Pharmacol.
, vol.16
, pp. 185-199
-
-
Johnson, M.K.1
-
18
-
-
0028280955
-
Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue
-
KUPFER A, AESCHLIMANN C, WERMUTH B AND CERNY T. (1994). Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue. Lancet, 343, 763-764.
-
(1994)
Lancet
, vol.343
, pp. 763-764
-
-
Kupfer, A.1
Aeschlimann, C.2
Wermuth, B.3
Cerny, T.4
-
19
-
-
0025022653
-
Ifosfamide pharmacokinetics and neurotoxicity
-
LEWIS LD AND MEANWELL CA. (1990). Ifosfamide pharmacokinetics and neurotoxicity. Lancet, 335, 175-176.
-
(1990)
Lancet
, vol.335
, pp. 175-176
-
-
Lewis, L.D.1
Meanwell, C.A.2
-
20
-
-
0024534384
-
The comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma
-
LIND MJ, MARGISON JM, CERNY T, THATCHER N AND WILKINSON PM. (1989a). The comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma. Cancer Res., 49, 753-757.
-
(1989)
Cancer Res.
, vol.49
, pp. 753-757
-
-
Lind, M.J.1
Margison, J.M.2
Cerny, T.3
Thatcher, N.4
Wilkinson, P.M.5
-
21
-
-
0024334410
-
The effect of ifosfamide and its metabolites on intracellular glutathione levels in vitro and in vivo
-
LIND MJ, MCGOWAN AT, HADFIELD JA, THATCHER N, CROWTHER D AND FOX BW. (1989b). The effect of ifosfamide and its metabolites on intracellular glutathione levels in vitro and in vivo. Biochem. Pharmacol., 38, 1835-1840.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 1835-1840
-
-
Lind, M.J.1
Mcgowan, A.T.2
Hadfield, J.A.3
Thatcher, N.4
Crowther, D.5
Fox, B.W.6
-
22
-
-
0026636286
-
Effect of pregnenolone-16α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice
-
MADHU C, MAZIASZ T AND KLASSEN CD. (1992). Effect of pregnenolone-16α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice. Toxicol. Appl. Pharmacol., 115, 191-198.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.115
, pp. 191-198
-
-
Madhu, C.1
Maziasz, T.2
Klassen, C.D.3
-
23
-
-
0019961364
-
Protective effect of diethyldithiocarbamate and carbon disulfide on experimental liver damage produced by various hepatotoxic agent
-
MASUDA Y AND NAKAYANIA N. (1982). Protective effect of diethyldithiocarbamate and carbon disulfide on experimental liver damage produced by various hepatotoxic agent. Biochem. Pharmacol., 31, 2713-2725.
-
(1982)
Biochem. Pharmacol.
, vol.31
, pp. 2713-2725
-
-
Masuda, Y.1
Nakayania, N.2
-
24
-
-
0024496048
-
Methods for depleting brain glutathione
-
MASUKAWA T, SAI MIDORI AND TOCHINO Y. (1989). Methods for depleting brain glutathione. Life Sciences, 44, 417-424.
-
(1989)
Life Sciences
, vol.44
, pp. 417-424
-
-
Masukawa, T.1
Sai Midori2
Tochino, Y.3
-
25
-
-
0019131878
-
High performance liquid chromatography analysis of nanomoles levels of glutathione, glutathione disulfide, and related thiols and disulfides
-
REED DJ, BABSON JR, BEATTY PW, BRODIE AE, ELLIS WW AND POTTER DW. (1980). High performance liquid chromatography analysis of nanomoles levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal. Biochem., 106, 55-62.
-
(1980)
Anal. Biochem.
, vol.106
, pp. 55-62
-
-
Reed, D.J.1
Babson, J.R.2
Beatty, P.W.3
Brodie, A.E.4
Ellis, W.W.5
Potter, D.W.6
-
26
-
-
0027431867
-
Molecular mechanisms of 2-chloroacetaldehyde induced cytotoxicity in isolated rat hepatocytes
-
SOOD C AND O'BRIEN PJ. (1993). Molecular mechanisms of 2-chloroacetaldehyde induced cytotoxicity in isolated rat hepatocytes. Biochem. Pharmacol. 46, 1621-1626.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1621-1626
-
-
Sood, C.1
O'Brien, P.J.2
-
27
-
-
0027956471
-
Chloroacetaldehyde induced hepatocyte cytotoxicity: Mechanisms for cytoprotection
-
SOOD C AND O'BRIEN PJ. (1994). Chloroacetaldehyde induced hepatocyte cytotoxicity: Mechanisms for cytoprotection. Biochem. Pharmacol., 48, 1025-1032.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1025-1032
-
-
Sood, C.1
O'Brien, P.J.2
-
28
-
-
8944250199
-
The involvement of cytochrome P4502E1 in 2-chloroacetaldehyde-induced hepatocyte cytotoxicity
-
submitted
-
SOOD C AND O'BRIEN PJ. (1996). The involvement of cytochrome P4502E1 in 2-chloroacetaldehyde-induced hepatocyte cytotoxicity. Cancer. Res. (submitted).
-
(1996)
Cancer. Res.
-
-
Sood, C.1
O'Brien, P.J.2
-
29
-
-
0015333734
-
Unexpected toxicity in patients treated with iphosphamide
-
VAN DYKK JJ, VAN DER MERWE AM AND FALKSON G. (1972). Unexpected toxicity in patients treated with iphosphamide. Cancer Res., 32, 921-924.
-
(1972)
Cancer Res.
, vol.32
, pp. 921-924
-
-
Van Dykk, J.J.1
Van Der Merwe, A.M.2
Falkson, G.3
-
30
-
-
0028354930
-
Ifosfamide stereoselective dechlorethylation and neurotoxicity
-
WAINER IW, DUCHARME J, GRANVIL CP AND TRUDEAU M. (1994). Ifosfamide stereoselective dechlorethylation and neurotoxicity. Lancet, 343, 982-983.
-
(1994)
Lancet
, vol.343
, pp. 982-983
-
-
Wainer, I.W.1
Ducharme, J.2
Granvil, C.P.3
Trudeau, M.4
-
31
-
-
0028178551
-
Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide
-
WALKER D, FLINOIS JP, MONKMAN SC, BELOC C, BODDY AV, CHOLERTON S, DALY AK, LIND MJ, PEARSON ADJ, BEAUNE PH AND IDLE JR. (1994). Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide. Biochem. Pharmacol., 47, 1157-1163.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1157-1163
-
-
Walker, D.1
Flinois, J.P.2
Monkman, S.C.3
Beloc, C.4
Boddy, A.V.5
Cholerton, S.6
Daly, A.K.7
Lind, M.J.8
Pearson, A.D.J.9
Beaune, P.H.10
Idle, J.R.11
-
32
-
-
0028118901
-
Effect of ethanol on cytochrome P450 in the rat brain
-
WARNER M AND GUSTAFSSON J-A. (1994). Effect of ethanol on cytochrome P450 in the rat brain. Proc. Natl Acad. Sci. USA, 91, 1019-1023.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 1019-1023
-
-
Warner, M.1
Gustafsson, J.-A.2
-
33
-
-
0027174822
-
Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes
-
WEBER GF AND WAXMAN DJ. (1993). Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes. Biochem. Pharmacol., 45, 1685-1694.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1685-1694
-
-
Weber, G.F.1
Waxman, D.J.2
|