메뉴 건너뛰기




Volumn 74, Issue SUPPL. XXVII, 1996, Pages

2-Chloroacetaldehyde-induced cerebral glutathione depletion and neurotoxicity

Author keywords

Chloroethanol; Ifosfamide; P450

Indexed keywords

2 CHLOROETHANOL; 2 CYCLOHEXENONE; 4 METHYLPYRAZOLE; ACETYLCYSTEINE; ALCOHOL; CHLOROACETALDEHYDE; CYTOCHROME P450; DEXAMETHASONE; GLUTATHIONE; IFOSFAMIDE; PHENOBARBITAL; ACETALDEHYDE; ALKYLATING AGENT; CYTOCHROME P450 2E1; DRUG DERIVATIVE;

EID: 0029977119     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (46)

References (33)
  • 1
    • 0025742993 scopus 로고
    • Dose- and time-dependent effect of an acute 2-amino-1,2,4-triazole injection on rat brain catalase activity
    • ARAGON CM, ROGAN F AND AMIT Z. (1991). Dose- and time-dependent effect of an acute 2-amino-1,2,4-triazole injection on rat brain catalase activity. Biochem. Pharmacol., 42, 699-702.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 699-702
    • Aragon, C.M.1    Rogan, F.2    Amit, Z.3
  • 2
    • 0021881114 scopus 로고
    • Ifosfamide pharmacology, safety and therapeutic potential
    • BRADE WP, HERDRICH K AND VARINI M. (1985). Ifosfamide pharmacology, safety and therapeutic potential. Cancer Treat. Rev., 12, 1-47.
    • (1985) Cancer Treat. Rev. , vol.12 , pp. 1-47
    • Brade, W.P.1    Herdrich, K.2    Varini, M.3
  • 3
    • 0022486199 scopus 로고
    • Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity
    • CAVALLETTI E, TOFANETTI O AND ZUNINO F. (1986). Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity. Cancer Lett., 32, 1-6.
    • (1986) Cancer Lett. , vol.32 , pp. 1-6
    • Cavalletti, E.1    Tofanetti, O.2    Zunino, F.3
  • 4
    • 0017227825 scopus 로고
    • Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde
    • CEDERBAUM AI AND RUBIN E. (1976). Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde. Biochem. Pharmacol., 25, 963-973.
    • (1976) Biochem. Pharmacol. , vol.25 , pp. 963-973
    • Cederbaum, A.I.1    Rubin, E.2
  • 6
    • 0022541787 scopus 로고
    • Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: Studies with N-acetyl-D-cysteine in mice
    • CORCORAN GB AND WONG BK. (1986). Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: Studies with N-acetyl-D-cysteine in mice. J. Pharmacol. Exp. Ther., 238, 54-61.
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 54-61
    • Corcoran, G.B.1    Wong, B.K.2
  • 7
    • 0018749594 scopus 로고
    • Cyclophosphamide cystitis identification of acrolein as a causative agent
    • COX PJ. (1979). Cyclophosphamide cystitis identification of acrolein as a causative agent. Biochem. Pharmacol., 28, 2045-2049.
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 2045-2049
    • Cox, P.J.1
  • 8
    • 77957179532 scopus 로고
    • Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in the male B6C3F1 mouse
    • DANIEL FB, DE ANGELO AB, STOBER JA, OLSON GR AND PAGE NP. (1992). Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in the male B6C3F1 mouse. Fund. Appl. Toxicol., 19, 159-168.
    • (1992) Fund. Appl. Toxicol. , vol.19 , pp. 159-168
    • Daniel, F.B.1    De Angelo, A.B.2    Stober, J.A.3    Olson, G.R.4    Page, N.P.5
  • 10
  • 11
    • 0028222128 scopus 로고
    • Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration
    • FORKERT PG, REDZA ZM, MANGOS S, PARK SS AND TAM S-P. (1994). Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration. Drug Metabol. Disp., 22, 248-253.
    • (1994) Drug Metabol. Disp. , vol.22 , pp. 248-253
    • Forkert, P.G.1    Redza, Z.M.2    Mangos, S.3    Park, S.S.4    Tam, S.-P.5
  • 12
    • 0023912974 scopus 로고
    • Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors
    • GIERON MA, BARAK LS AND ESTRADA J. (1988). Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors. J. Neuro-Oncol., 6, 29-30.
    • (1988) J. Neuro-Oncol. , vol.6 , pp. 29-30
    • Gieron, M.A.1    Barak, L.S.2    Estrada, J.3
  • 13
    • 0023035082 scopus 로고
    • Dechloroethylation of ifosfamide and neurotoxicity
    • GOREN MP, WRIGHT RK, PRATT CB AND PELL FE. (1986). Dechloroethylation of ifosfamide and neurotoxicity. Lancet, 2, 1219-1220.
    • (1986) Lancet , vol.2 , pp. 1219-1220
    • Goren, M.P.1    Wright, R.K.2    Pratt, C.B.3    Pell, F.E.4
  • 14
    • 0345654274 scopus 로고
    • Glutathione: Interorgan translocation, turnover, and metabolism
    • GRIFFITH OW AND MEISTER A. (1979). Glutathione: Interorgan translocation, turnover, and metabolism. Proc. Natl Acad. Sci. USA, 76, 5606-5610.
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 5606-5610
    • Griffith, O.W.1    Meister, A.2
  • 15
    • 0019514883 scopus 로고
    • Changes in glutathione in acute and chronic alcohol intoxication
    • GUERRI C AND GRISOLIA S. (1980). Changes in glutathione in acute and chronic alcohol intoxication. Pharmacol. Biochem. Behav., 13, 53-61.
    • (1980) Pharmacol. Biochem. Behav. , vol.13 , pp. 53-61
    • Guerri, C.1    Grisolia, S.2
  • 16
    • 0020680491 scopus 로고
    • The alcohol dehydrogenase gene complex on chromosome 3 of the mouse
    • Rattazzi MC, Scandalios JG, Whit GS (eds) Alan R Liss: New York
    • HOLMES RS, DULEY JA AND BURNELL JN. (1983). The alcohol dehydrogenase gene complex on chromosome 3 of the mouse. In Isozymes, Current Topics in Biological and Medical Research, Rattazzi MC, Scandalios JG, Whit GS (eds) pp. 155-174. Alan R Liss: New York.
    • (1983) Isozymes, Current Topics in Biological and Medical Research , pp. 155-174
    • Holmes, R.S.1    Duley, J.A.2    Burnell, J.N.3
  • 17
    • 0006853058 scopus 로고
    • Metabolism of 2-chloroethanol in the rat
    • JOHNSON MK. (1967). Metabolism of 2-chloroethanol in the rat. Biochem. Pharmacol., 16, 185-199.
    • (1967) Biochem. Pharmacol. , vol.16 , pp. 185-199
    • Johnson, M.K.1
  • 18
    • 0028280955 scopus 로고
    • Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue
    • KUPFER A, AESCHLIMANN C, WERMUTH B AND CERNY T. (1994). Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue. Lancet, 343, 763-764.
    • (1994) Lancet , vol.343 , pp. 763-764
    • Kupfer, A.1    Aeschlimann, C.2    Wermuth, B.3    Cerny, T.4
  • 19
    • 0025022653 scopus 로고
    • Ifosfamide pharmacokinetics and neurotoxicity
    • LEWIS LD AND MEANWELL CA. (1990). Ifosfamide pharmacokinetics and neurotoxicity. Lancet, 335, 175-176.
    • (1990) Lancet , vol.335 , pp. 175-176
    • Lewis, L.D.1    Meanwell, C.A.2
  • 20
    • 0024534384 scopus 로고
    • The comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma
    • LIND MJ, MARGISON JM, CERNY T, THATCHER N AND WILKINSON PM. (1989a). The comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma. Cancer Res., 49, 753-757.
    • (1989) Cancer Res. , vol.49 , pp. 753-757
    • Lind, M.J.1    Margison, J.M.2    Cerny, T.3    Thatcher, N.4    Wilkinson, P.M.5
  • 21
    • 0024334410 scopus 로고
    • The effect of ifosfamide and its metabolites on intracellular glutathione levels in vitro and in vivo
    • LIND MJ, MCGOWAN AT, HADFIELD JA, THATCHER N, CROWTHER D AND FOX BW. (1989b). The effect of ifosfamide and its metabolites on intracellular glutathione levels in vitro and in vivo. Biochem. Pharmacol., 38, 1835-1840.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1835-1840
    • Lind, M.J.1    Mcgowan, A.T.2    Hadfield, J.A.3    Thatcher, N.4    Crowther, D.5    Fox, B.W.6
  • 22
    • 0026636286 scopus 로고
    • Effect of pregnenolone-16α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice
    • MADHU C, MAZIASZ T AND KLASSEN CD. (1992). Effect of pregnenolone-16α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice. Toxicol. Appl. Pharmacol., 115, 191-198.
    • (1992) Toxicol. Appl. Pharmacol. , vol.115 , pp. 191-198
    • Madhu, C.1    Maziasz, T.2    Klassen, C.D.3
  • 23
    • 0019961364 scopus 로고
    • Protective effect of diethyldithiocarbamate and carbon disulfide on experimental liver damage produced by various hepatotoxic agent
    • MASUDA Y AND NAKAYANIA N. (1982). Protective effect of diethyldithiocarbamate and carbon disulfide on experimental liver damage produced by various hepatotoxic agent. Biochem. Pharmacol., 31, 2713-2725.
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 2713-2725
    • Masuda, Y.1    Nakayania, N.2
  • 24
    • 0024496048 scopus 로고
    • Methods for depleting brain glutathione
    • MASUKAWA T, SAI MIDORI AND TOCHINO Y. (1989). Methods for depleting brain glutathione. Life Sciences, 44, 417-424.
    • (1989) Life Sciences , vol.44 , pp. 417-424
    • Masukawa, T.1    Sai Midori2    Tochino, Y.3
  • 25
    • 0019131878 scopus 로고
    • High performance liquid chromatography analysis of nanomoles levels of glutathione, glutathione disulfide, and related thiols and disulfides
    • REED DJ, BABSON JR, BEATTY PW, BRODIE AE, ELLIS WW AND POTTER DW. (1980). High performance liquid chromatography analysis of nanomoles levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal. Biochem., 106, 55-62.
    • (1980) Anal. Biochem. , vol.106 , pp. 55-62
    • Reed, D.J.1    Babson, J.R.2    Beatty, P.W.3    Brodie, A.E.4    Ellis, W.W.5    Potter, D.W.6
  • 26
    • 0027431867 scopus 로고
    • Molecular mechanisms of 2-chloroacetaldehyde induced cytotoxicity in isolated rat hepatocytes
    • SOOD C AND O'BRIEN PJ. (1993). Molecular mechanisms of 2-chloroacetaldehyde induced cytotoxicity in isolated rat hepatocytes. Biochem. Pharmacol. 46, 1621-1626.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1621-1626
    • Sood, C.1    O'Brien, P.J.2
  • 27
    • 0027956471 scopus 로고
    • Chloroacetaldehyde induced hepatocyte cytotoxicity: Mechanisms for cytoprotection
    • SOOD C AND O'BRIEN PJ. (1994). Chloroacetaldehyde induced hepatocyte cytotoxicity: Mechanisms for cytoprotection. Biochem. Pharmacol., 48, 1025-1032.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1025-1032
    • Sood, C.1    O'Brien, P.J.2
  • 28
    • 8944250199 scopus 로고    scopus 로고
    • The involvement of cytochrome P4502E1 in 2-chloroacetaldehyde-induced hepatocyte cytotoxicity
    • submitted
    • SOOD C AND O'BRIEN PJ. (1996). The involvement of cytochrome P4502E1 in 2-chloroacetaldehyde-induced hepatocyte cytotoxicity. Cancer. Res. (submitted).
    • (1996) Cancer. Res.
    • Sood, C.1    O'Brien, P.J.2
  • 29
    • 0015333734 scopus 로고
    • Unexpected toxicity in patients treated with iphosphamide
    • VAN DYKK JJ, VAN DER MERWE AM AND FALKSON G. (1972). Unexpected toxicity in patients treated with iphosphamide. Cancer Res., 32, 921-924.
    • (1972) Cancer Res. , vol.32 , pp. 921-924
    • Van Dykk, J.J.1    Van Der Merwe, A.M.2    Falkson, G.3
  • 30
    • 0028354930 scopus 로고
    • Ifosfamide stereoselective dechlorethylation and neurotoxicity
    • WAINER IW, DUCHARME J, GRANVIL CP AND TRUDEAU M. (1994). Ifosfamide stereoselective dechlorethylation and neurotoxicity. Lancet, 343, 982-983.
    • (1994) Lancet , vol.343 , pp. 982-983
    • Wainer, I.W.1    Ducharme, J.2    Granvil, C.P.3    Trudeau, M.4
  • 32
    • 0028118901 scopus 로고
    • Effect of ethanol on cytochrome P450 in the rat brain
    • WARNER M AND GUSTAFSSON J-A. (1994). Effect of ethanol on cytochrome P450 in the rat brain. Proc. Natl Acad. Sci. USA, 91, 1019-1023.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 1019-1023
    • Warner, M.1    Gustafsson, J.-A.2
  • 33
    • 0027174822 scopus 로고
    • Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes
    • WEBER GF AND WAXMAN DJ. (1993). Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes. Biochem. Pharmacol., 45, 1685-1694.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 1685-1694
    • Weber, G.F.1    Waxman, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.