Effects of aspiration lesions of hippocampus or overlying neocortex on concurrent and configural object discriminations in rats

Behavioural Brain Research

Volumn 77, Issue 1-2, 1996, Pages 165-174

  Deacon, Robert M J ^a   Rawlins, J Nicholas P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Concurrent learning; Configural learning; Cortex; Hippocampus; Memory

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN INJURY; CONTROLLED STUDY; DISCRIMINATION LEARNING; HIPPOCAMPUS; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029977088     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-4328(95)00230-8     Document Type: Article

References (37)

1. Aggleton, J.P., One-trial object recognition by rats, Q. J. Exp. Psychol., 37B, (1985) 279-294.
2. Aggleton, J.P., Kentridge, R.W. and Sembi, S., Lesions of the fornix but not the amygdala impair the acquisition of concurrent discriminations by rats, Behav. Brain Res., 48 (1991) 103-112.
3. Aggleton, J.P., Shaw, C. and Gaffan, E.A., The performance of postencephalitic amnesic subjects on two behavioural tests of memory: concurrent discrimination learning and delayed matching-to-sample, Cortex, 28, (1992) 359-372.
4. Alvarado, M.C. and Rudy, J.W., Some properties of configural learning: an investigation of the transverse-patterning problem, J. Exp. Psychol.: Anim. Behav. Proc., 18, (1992) 145-153.
5. Bauer, R.H., Brightness discrimination of pretrained and nonpretrained hippocampal rats reinforced for choosing brighter or dimmer alternatives, J. Comp. Physiol. Psychol., 87 (1974) 987-996.
6. Bussey, T.J., Muir, J.L. and Robbins, T.W., The effects of cingulate cortex lesions on acquisition of a simple visual discrimination and reversal, and an 8-pair concurrent discrimination task in rats: the use of a novel touchscreen approach, Brain Research Association meeting, Oxford (1995) Abstr. 47.7.
7. Davidson, T.L., McKernan, M.G. and Jarrard, L.E., Hippocampal lesions do not impair negative patterning: a challenge to configural association learning, Behav. Neurosci., 107 (1993) 227-234.
8. DiMattia, B.D. and Kesner, R.K., Spatial cognitive maps: differential role of parietal cortex and hippocampal formation, Behav. Neurosci., 102 (1988) 471-480.
9. Eichenbaum, H., Mathews, P. and Cohen, N.J., Further studies of hippocampal representation during odor discrimination learning, Behav. Neurosci., 103 (1989) 1207-1216.
10. Ennaceur, A. and Aggleton, J.P., Spontaneous recognition of object configurations in rats: effects of fornix lesions, Exp. Brain Res., 100 (1994) 85-92.
11. Gaffan, E.A., Aggleton, J.P., Gaffan, D. and Shaw, C., Concurrent and sequential pattern discrimination learning by patients with Korsakoff amnesia, Cortex, 26 (1990) 381-397.
12. Gallagher, M. and Holland, P.C., Preserved configural learning and spatial learning impairment in rats with hippocampal damage, Hippocampus, 2 (1992) 81-88.
13. Hunt, P.R., Neave, N., Shaw, C. and Aggleton, J.P., The effects of lesions to the fornix and dorsomedial thalamus on concurrent discrimination learning by rats, Behav. Brain Res., 62 (1994) 195-205.
14. Irle, E., An analysis of the correlation between lesion size, localization and behavioral effects in 283 published studies of cortical and subcortical lesions in old-world monkeys, Brain Res. Rev., 15, (1990) 181-213.
15. Irle, E., Kessler, J. and Markowitsch, H.J., Primate learning tasks reveal strong impairments in patients with presenile or senile dementia of the Alzheimer type, Brain Cog., 6, (1987) 429-449.
16. Jarrard, L. and Hyko, A., Complementary roles for the hippocampus and entorhinal/perirhinal cortex in the acquisition of spatial and nonspatial tasks in the rat, Soc. Neurosci. Abstr., 20, (1994) 1015.
17. Joseph, R., Neuropsychology, Neuropsychiatry and Behavioral Neurology, Plenum Press, New York, 1990.
18. Kessler, J., Irle, E. and Markowitsch, H.J., Korsakoff and alcoholic subjects are severely impaired in animal tasks of associative memory, Neuropsychologia, 24, (1986) 671-680.
19. Kimble, D.P., Hippocampus and internal inhibition, Psychol. Bull., 70, (1968) 285-295.
20. Malamut, B.L., Saunders, R.C. and Mishkin, M., Monkeys with combined amygdalo-hippocampal lesions succeed in object discrimination learning despite 24-hour intertrial intervals, Behav. Neurosci., 98 (1984) 759-769.
21. Mumby, D.G., Pinel, J.P.J., Kornecook, T.J., Shen, M.J. and Redila, V.A., Memory deficits following lesions of hippocampus or amygdala in rat: assessment by an object-memory test battery, Psychobiology, 23 (1995) 23-36.
22. Olton, D.S. and Shapiro, M.L., Mnemonic dissociations: the power of parameters, J. Cog. Neurosci., 4 (1992) 200-207.
23. Oscar-Berman, M. and Zola-Morgan, S.M., Comparative neuropsychology and Korsakoff's syndrome. II-Two-choice visual discrimination learning, Neuropsychologia, 18 (1980) 513-525.
24. Pickering, A.D., The flexibility of implicit memory:. an exploration using discrimination learning. In M.J. Riddoch and G.W. Humphreys (Eds.), Cognitive Neuropsychology and Cognitive Rehabilitation, Lawrence Erlbaum, Hove, UK, 1994, pp. 549-569.
25. Rawlins, J.N.P. and Bennet, R.C., A headholder for visually guided surgery in rats, Physiol. Behav., 24 (1980) 415-416.
26. Rawlins, J.N.P., Deacon, R.M.J., Yee, B.K. and Cassaday, H.J., Does it still make sense to develop a declarative memory theory of hippocampal function? Behav. Brain Sci., 17 (1994) 492-493.
27. Rawlins, J.N.P., Lyford, G.L., Seferiades, A., Deacon, R.M.J. and Cassaday, H.J., Critical determinants of nonspatial working memory deficits in rats with conventional lesions of the hippocampus or fornix, Behav. Neurosci, 107 (1993) 420-433.
28. Reep, R.L., Chandler, H.C., King, V. and Corwin, J.V., Rat posterior parietal cortex: topography of corticocortical and thalamic connections, Exp. Brain Res., 100 (1994) 67-84.
29. Rothblat, L.A., Vnek, N., Gleason, T.C. and Kromer, L.F., Role of the parahippocampal region in spatial and non-spatial memory: effects of parahippocampal lesions on rewarded alternation and concurrent object discrimination learning in the rat, Behav. Brain Res., 55 (1993) 93-100.
30. Rudy, J.W. and Sutherland, R.J., The hippocampal formation is necessary for rats to learn and remember configural discriminations, Behav. Brain Res., 34 (1989) 97-109.
31. Saunders, R.C. and Weiskrantz, L., The effects of fornix transection and combined fornix transection, mamillary body lesions and hippocampal ablations on object-pair association memory in the rhesus monkey, 35 (1989) 85-94.
32. Save, E., Buhot, M.-C., Foreman, N. and Thinus-Blanc, C., Exploratory activity and response to a spatial change in rats with hippocampal or posterior parietal cortical lesions, Behav. Brain Res., 47 (1992) 113-127.
33. Squire, L.R., Zola-Morgan, S. and Chen, K.S., Human amnesia and animal models of amnesia: performance of amnesic patients on tests designed for the monkey, Behav. Neurosci., 102 (1988) 210-221.
34. Sutherland, R.J. and Rudy, J.W., Configural association theory: the role of the hippocampal formation in learning, memory, and amnesia, Psychobiology, 17 (1989) 129-144.
35. Whishaw, I.Q. and Tomie, J., Acquisition and retention by hippocampal rats of simple, conditional, and configural tasks using tactile and olfactory cues: implications for hippocampal function, Behav. Neurosci., 105 (1991) 787-797.
36. Wible, C.G., Shiber, J.R. and Olton, D.S., Hippocampus, fimbriafornix, amygdala and memory: object discriminations in rats, Behav. Neurosci., 106 (1992) 751-761.
37. Zola-Morgan, S., Squire, L.R. and Amaral, D.G., Lesions of the hippocampal formation but not lesions of the fornix or the mamillary nuclei produce long-lasting memory impairment in monkeys, J. Neurosci., 9 (1989) 898-913.