-
1
-
-
0028339820
-
Bioreductive drugs for cancer therapy: The search for tumor specificity
-
ADAMS GE AND STRATFORD IJ. (1994). Bioreductive drugs for cancer therapy: the search for tumor specificity. Int. J. Radiat. Oncol. Biol. Phys., 29, 231-238.
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 231-238
-
-
Adams, G.E.1
Stratford, I.J.2
-
2
-
-
0018194637
-
A general mechanism for microsomal activation of quinone anticancer agents to free radicals
-
BACHUR NR, GORDON SL AND GEE MVA. (1978). A general mechanism for microsomal activation of quinone anticancer agents to free radicals. Cancer Res., 38, 1745-1750.
-
(1978)
Cancer Res.
, vol.38
, pp. 1745-1750
-
-
Bachur, N.R.1
Gordon, S.L.2
Gee, M.V.A.3
-
3
-
-
0019904785
-
Secondary neoplasms in patients treated for cancer: Etiology and perspective
-
COLEMAN N. (1982). Secondary neoplasms in patients treated for cancer: etiology and perspective. Radiat. Res., 92, 188-200.
-
(1982)
Radiat. Res.
, vol.92
, pp. 188-200
-
-
Coleman, N.1
-
4
-
-
0021260579
-
Enhanced sensitivity of the C3H 10T1/2 cells transformation system to alkylating and chemotherapeutic agents by treatment with TPA
-
FRAZELLE JH, ALBERNETHY DJ AND BOREIKO CJ. (1984). Enhanced sensitivity of the C3H 10T1/2 cells transformation system to alkylating and chemotherapeutic agents by treatment with TPA. Environ. Mutagen., 6, 81-89.
-
(1984)
Environ. Mutagen.
, vol.6
, pp. 81-89
-
-
Frazelle, J.H.1
Albernethy, D.J.2
Boreiko, C.J.3
-
5
-
-
0025130113
-
Modulating factors in the expression of radiation induced oncogenic transformation
-
HALL EJ AND HEI TK. (1990). Modulating factors in the expression of radiation induced oncogenic transformation. Environ. Health Perspective, 88, 149-155.
-
(1990)
Environ. Health Perspective
, vol.88
, pp. 149-155
-
-
Hall, E.J.1
Hei, T.K.2
-
6
-
-
0025250570
-
Studies with bifunctional bioreductive drugs I. in vitro oncogenic transforming potential
-
HEI TK, HE ZY, PIAO CQ AND HALL EJ. (1990). Studies with bifunctional bioreductive drugs I. In vitro oncogenic transforming potential. Radiat. Res., 124, S44-S49.
-
(1990)
Radiat. Res.
, vol.124
-
-
Hei, T.K.1
He, Z.Y.2
Piao, C.Q.3
Hall, E.J.4
-
7
-
-
0026519120
-
Mechanism of oncogenicity for bioreductive drugs
-
HEI TK, PIAO CQ, HE ZY AND HALL EJ. (1992). Mechanism of oncogenicity for bioreductive drugs. Int. J. Radiat. Oncol. Biol. Phys., 22, 747-750.
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.22
, pp. 747-750
-
-
Hei, T.K.1
Piao, C.Q.2
He, Z.Y.3
Hall, E.J.4
-
8
-
-
0023546316
-
Second malignancies from adjuvant chemotherapy
-
HENDERSON IC AND GELMAN R. (1987). Second malignancies from adjuvant chemotherapy. J. Clin. Oncol., 5, 1135-1137.
-
(1987)
J. Clin. Oncol.
, vol.5
, pp. 1135-1137
-
-
Henderson, I.C.1
Gelman, R.2
-
9
-
-
0027450014
-
E09: A novel bioreductive alkylating indoloquinone with preferential solid tumor activity and lack of bone marrow toxicity in preclinical models
-
HENDRIKS HR, PIZAO PE, BERGER DP, KOOISTRA KL, BIBBY MC, BOVEN E, DREEF-VAN DER MEULEN HC, HENRAR REC, FIEBIG HH, DOUBLE JA, HORNSTRA HW, PINEDO HM, WORKMAN P AND SCHWARTSMANN G. (1993). E09: A novel bioreductive alkylating indoloquinone with preferential solid tumor activity and lack of bone marrow toxicity in preclinical models. Eur. J. Cancer, 6, 897-906.
-
(1993)
Eur. J. Cancer
, vol.6
, pp. 897-906
-
-
Hendriks, H.R.1
Pizao, P.E.2
Berger, D.P.3
Kooistra, K.L.4
Bibby, M.C.5
Boven, E.6
Dreef-Van Der Meulen, H.C.7
Henrar, R.E.C.8
Fiebig, H.H.9
Double, J.A.10
Hornstra, H.W.11
Pinedo, H.M.12
Workman, P.13
Schwartsmann, G.14
-
10
-
-
0021254309
-
Evidence that a second event in X-ray induced oncogenic transformation in vitro occurred during cellular proliferation
-
KENNEDY AR AND LITTLE JB. (1984). Evidence that a second event in X-ray induced oncogenic transformation in vitro occurred during cellular proliferation. Radiat. Res., 99, 228-248.
-
(1984)
Radiat. Res.
, vol.99
, pp. 228-248
-
-
Kennedy, A.R.1
Little, J.B.2
-
11
-
-
0030071333
-
Fused pyrazine mono-N-oxides as bioreductive drugs. II. Cytotoxicity in human cells and oncogenicity in rodent transformation assay
-
LANGMUIR VK, LADEROUTE KR, MENDONCA HL, SUTHERLAND RM, HEI TK, LIU SX, HALL EJ, NAYLOR MA AND ADAMS GE. (1996). Fused pyrazine mono-N-oxides as bioreductive drugs. II. Cytotoxicity in human cells and oncogenicity in rodent transformation assay. Int. J. Radiat. Oncol. Biol. Phys., 34, 79-84.
-
(1996)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.34
, pp. 79-84
-
-
Langmuir, V.K.1
Laderoute, K.R.2
Mendonca, H.L.3
Sutherland, R.M.4
Hei, T.K.5
Liu, S.X.6
Hall, E.J.7
Naylor, M.A.8
Adams, G.E.9
-
12
-
-
0028360595
-
Radiolytic and photochemical reduction of the hypoxic cytotoxin 1,2-dihydro-8-(4-methylpiperazinyl)-4-phenylimidazo [1,2-α] pyridopyrazine-5 oxide (RB 90740) and a potential mechanism for hypoxia selective toxicity
-
NAYLOR MA, SUTTON BM, NOLAN J, O'NEILL P, FIELDEN EM, ADAMS GE AND STRATFORD IJ. (1994). Radiolytic and photochemical reduction of the hypoxic cytotoxin 1,2-dihydro-8-(4-methylpiperazinyl)-4-phenylimidazo [1,2-α] pyridopyrazine-5 oxide (RB 90740) and a potential mechanism for hypoxia selective toxicity. Int. J. Radiat. Oncol. Biol. Phys., 29, 333-337.
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 333-337
-
-
Naylor, M.A.1
Sutton, B.M.2
Nolan, J.3
O'Neill, P.4
Fielden, E.M.5
Adams, G.E.6
Stratford, I.J.7
-
13
-
-
0028961623
-
Fused pyrazine mon-N-oxides as bio-reductive drugs III. Characteristics of RB 90740 in vitro and in vivo
-
NAYLOR MA, ADAMS GE, HAIGH A, COLE S, JENNER T, NAOMI R, SIEMANN D, STEPHENS MA AND STRATFORD IA. (1995). Fused pyrazine mon-N-oxides as bio-reductive drugs III. Characteristics of RB 90740 in vitro and in vivo. Anticancer Drugs, 6, 259-269.
-
(1995)
Anticancer Drugs
, vol.6
, pp. 259-269
-
-
Naylor, M.A.1
Adams, G.E.2
Haigh, A.3
Cole, S.4
Jenner, T.5
Naomi, R.6
Siemann, D.7
Stephens, M.A.8
Stratford, I.A.9
-
14
-
-
0015732254
-
Quantitative and qualitative studies of chemical transformation of clonal C3H mouse embryo cells sensitive to post-confluence inhibition of cell division
-
REZNIKOFF CA, BERTRAM JS, BRANKOW DW AND HEIDELBERGER C. (1973). Quantitative and qualitative studies of chemical transformation of clonal C3H mouse embryo cells sensitive to post-confluence inhibition of cell division. Cancer Res., 33, 3229-3249.
-
(1973)
Cancer Res.
, vol.33
, pp. 3229-3249
-
-
Reznikoff, C.A.1
Bertram, J.S.2
Brankow, D.W.3
Heidelberger, C.4
-
15
-
-
0026503552
-
The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins
-
WALTON MI, SUGGET N AND WORKMAN P. (1992). The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins. Int. J. Radiat. Oncol. Bio. Phys., 22, 643-647.
-
(1992)
Int. J. Radiat. Oncol. Bio. Phys.
, vol.22
, pp. 643-647
-
-
Walton, M.I.1
Sugget, N.2
Workman, P.3
-
16
-
-
0026462426
-
Keynote address: Bioreductive mechanisms
-
WORKMAN P. (1992). Keynote address: bioreductive mechanisms. Int. J. Radiat. Oncol. Bio. Phys., 22, 631-637.
-
(1992)
Int. J. Radiat. Oncol. Bio. Phys.
, vol.22
, pp. 631-637
-
-
Workman, P.1
-
17
-
-
0024313837
-
DT-Diaphorase: Questionable role in mitomycin C resistance, but a target for novel bioreductive drugs
-
WORKMAN P, WALTON MI, POWIS G AND SCHLAGER JJ. (1989). DT-Diaphorase: questionable role in mitomycin C resistance, but a target for novel bioreductive drugs. Br. J. Cancer, 60, 800-802.
-
(1989)
Br. J. Cancer
, vol.60
, pp. 800-802
-
-
Workman, P.1
Walton, M.I.2
Powis, G.3
Schlager, J.J.4
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