Chemopreventive Effects of 24R,25-dihydroxyvitamin D3, a vitamin D3 derivative, on glandular stomach carcinogenesis induced in rats by N-Methyl-N'-nitro-N-nitrosoguanidine and sodium chloride

Cancer Research

Volumn 56, Issue 12, 1996, Pages 2767-2770

  Ikezaki, Shinichiro ^a,b   Nishikawa, Akiyoshi ^a   Furukawa, Fumio ^a   Tanakamaru, Zen Yo ^a,b   Kim, Hyoung Chin ^a   Mori, Hideki ^b   Takahashi, Michihito ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

24,25 DIHYDROXYCOLECALCIFEROL; METHYLNITRONITROSOGUANIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM EXCRETION; CANCER INHIBITION; CANCER PREVENTION; DOSE RESPONSE; DRUG EFFECT; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STOMACH CARCINOGENESIS; STOMACH CARCINOMA;

24,25-DIHYDROXYVITAMIN D 3; ADENOCARCINOMA; ANIMALS; CALCIUM; CARCINOGENS; DRUG SCREENING ASSAYS, ANTITUMOR; HYPERPLASIA; MALE; METHYLNITRONITROSOGUANIDINE; PHOSPHORUS; PRECANCEROUS CONDITIONS; RATS; RATS, WISTAR; SODIUM CHLORIDE; STOMACH; STOMACH NEOPLASMS;

EID: 0029976568     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Garland, C., Barren-Connor, E., Rossof, A. H , Shekelle, R B., Ciqui, M H , and Paul, O. Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet, 1: 307-309, 1985.
2. 3. Carcinogenesis (Lond.), 9: 187-190, 1988
3. Wargovich, M J., Allnutt, D., Palmer, C., Anaya, P , and Stephens, L C. Inhibition of the promotional phase of azoxymethane-induced colon carcinogenesis in the F344 rat by calcium lactate: effect of stimulating two human nutrient density levels. Cancer Lett , 53: 17-25, 1990
4. Nishikawa, A., Furukawa, F., Mitsui, M., Enami, T , Kawanishi, T., Hasegawa, T., and Takahashi, M. Inhibitory effect of calcium chloride on gastric carcinogenesis in rats after treatment with N-methyl-N′-nitro-N-nitrosoguanidine and sodium chloride. Carcinogenesis (Lond). 13: 1155-1158, 1992.
5. 3 in chemically induced rat colon carcinogenesis. Carcinogenesis (Lond.), 13. 2293-2298, 1992
6. 3 Cancer Res., 45: 5426-5430, 1985.
7. 3 inhibits phorbol ester-dependent chemical carcinogenesis in mouse skin. Biochem. Biophys. Res. Commun., 116: 605-611, 1983
8. 3 on the development and steroid hormone receptor contents of DMBA-induced rat mammary tumors. Oncology (Basel). 46: 273-276, 1989.
9. Fenwick, J C., Smith, K. Smith, J , and Flik, G. Effect of various vitamin D analogs on plasma calcium, phosphorus, and intestinal calcium absorption in fed and unfed American eels, Anguilla rostrata Gen. Comp Endocrinol., 55 398-404, 1984.
10. 3 in rats. In Vivo (Athens), 1: 347-350, 1987.
11. 3 on the formation and function of osteoclastic cells. Calcif Tissue Int., 52: 255-260, 1993
12. 3. Bone (Elmsford), 10: 117-123, 1989
13. 3 in predialysis renal insufficiency, biochemistry and histomorphometry of cancellous bone. J. Bone Miner. Res., 10: 197-204, 1995.
14. Ornoy, A., Goodwin, D., Noff, D., and Edelstein, S. 24,25-Dihydroxyvitamin D is a metabolite of vitamin D essential for bone formation. Nature (Lond.), 276. 517-519, 1978.
15. Sugimura, T., and Fujimura, S. Tumor production in glandular stomach of rats by N-methyl-N′-nitro-N-nitrosoguanidine. Nature (Lond.), 216: 943-944, 1967.
16. Takahashi, M , Kokubo, T , Furukawa, F., Kurokawa, Y , and Hayashi, Y. Effects of sodium chloride, saccharin, phenobarbital, and aspirin on gastric carcinogenesis in rats after initiation with N-methyl-N′-nitro-N-nitrosoguanidine. Gann. 75: 494-501, 1984.
17. Nishikawa, A , Furukawa, F, Mitsui, M., Enami, T , Imazawa, T., Ikezaki, S., and Takahashi, M. Dose-dependent promotion effects of potassium chloride on glandular stomach carcinogenesis in rats after initiation with N-methyl-N′-nitro-N-nitrosoguanidine and the synergistic influence with sodium chloride. Cancer Res., 55: 5238-5241, 1995
18. Slob, I C M., Lambregts, J. L. M. C., Schuit, A. J., and Kok, F. J Calcium intake and 28-year gastrointestinal cancer mortality in Dutch civil servants. Int. J Cancer, 54: 20-25, 1993
19. 3. Endocrinology, 3. 1950-1957, 1983
20. Walters, M. R. Newly identified actions of the vitamin D endocrine system. Endocr. Rev., 13: 719-754, 1992.
21. 3 and the immune system. Proc Soc. Exp Biol Med , 191: 238-245, 1989.
22. Reinhardt, T. A , and Hustmyer, F. G. Role of vitamin D in the immune system. J Dairy Sci., 70: 952-962, 1987.
23. 3 of induction of epidermal ornithine decarboxylase caused by 12-O-tetradecanoylphorbol-13-acetate and teleocidin B Cancer Res , 44: 1387-1391, 1984.
24. 3-treated animals Cancer Res., 47. 5031-5035, 1987.
25. 3 in perfused rat liver. Biochem Biophys Res. Commun., 66: 632-638, 1975.
26. Boyle, I T , Gray, R. W., and DeLuca, H F. Regulation by calcium of in vivo synthesis of 1,25-dihydroxycholecalciferol and 21,25-dihydroxycholecalciferol. Proc. Natl. Acad Sci USA, 68: 2131-2134, 1971.
27. Giguere, V., Yang, N, Segui, P , and Evans, R M. Identification of a new class of steroid hormone receptors. Nature (Lond.), 331: 91-94, 1988.
28. 3 receptors in human carcinomas: a pilot study. Cancer Res., 51: 2021-2024, 1991.
29. 3 receptor in the parathyroid gland of the rachitic chick. Biochem. Biophys Res Commun., 100: 551-558, 1981
30. Somjen, D., Somjen, G. J , Weisman, Y , and Binderman, I. Evidence for 24,25-dihydroxcholecalciferol receptors in long bones of newborn rats Biochem J., 204. 31-36, 1982.