A use-dependent sodium channel antagonist, 619C89, in reduction of ischemic brain damage and glutamate release after acute subdural hematoma in the rat

Journal of Neurosurgery

Volumn 85, Issue 1, 1996, Pages 104-111

  Tsuchida, Eiji ^a   Harms, John F ^a   Woodward, John J ^a   Bullock, Ross ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

619C89; acute subdural hematoma; excitatory amino acid sodium channel antagonist; rat

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; SIPATRIGINE; SODIUM CHANNEL BLOCKING AGENT; THREONINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; HEAD INJURY; HISTOPATHOLOGY; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SUBDURAL HEMATOMA;

EID: 0029976459     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.85.1.0104     Document Type: Article

References (52)

1. Adams JH, Graham DI, Gennarelli TA: Head injury in man and experimental animals: neuropathology. Acta Neurochir Suppl 32:15-30, 1983
2. Benveniste H, Drejer J, Schousboe A, et al: Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 43:1369-1374, 1984
3. Bouma GJ, Muizelaar JP, Stringer WA, et al: Ultra-early evaluation of regional cerebral blood flow in severely head-injured patients using xenon-enhanced computerized tomography. J Neurosurg 77:360-368, 1992
4. Brierley JB, Meldrum BS, Brown AW: The threshold and neuropathology of cerebral "anoxic-ischemic" cell change. Arch Neurol 29:367-374, 1973
5. Buchan A, Li H, Pulsinelli WA: The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats. J Neuroscil 1:1049-1056, 1991
6. Buchan AM, Li H, Cho S, et al: Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. Neurosci Lett 132:255-258, 1991
7. Bullock R, Butcher SP, Chen MH, et al: Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat. J Neurosurg 74:794-802, 1991
8. Bullock R, Fijisawa H: The role of glutamate antagonists for the treatment of CNS injury. J Neurotrauma 9 (Suppl 2): S443-S461, 1992
9. Bullock R, Teasdale G: Surgical management of traumatic intracranial haematomas in Braakman R (ed): Handbook of Clinical Neurology. Vol. 57: Head Injury. Amsterdam: Elsevier, 1990, pp 249-297
10. Bullock R, Zauner A, Tsuji O, et al: Excitatory amino acid release after severe human head trauma: effect of intracranial pressure and cerebral perfusion pressure changes, in Nagai H, Kamiya K, Ishii S (eds): Intracranial Pressure IX. Tokyo: Springer-Verlag, 1994, pp 264-267
11. Bullock R, Zauner A, Tsuji O, et al: Patterns of excitatory amino acid release and ionic flux after severe human head trauma: effect of intracranial pressure and cerebral perfusion changes, in Nagai H, Kamiya K, Ishi S (eds): Intracranial Pressure IX. Tokyo: Springer-Verlag, 1994, pp 247-267
12. Chen MH, Bullock R, Graham DI, et al: Ischemic neuronal damage after acute subdural hematoma in the rat: effects of pretreatment with a glutamate antagonist. J Neurosurg 74: 944-950, 1991
13. Duhaime AC, Gennarelli LM, Boardman C: Neuroprotection by oral dextromethorphan in acute experimental subdural hematoma in the rat. J Neurotrauma 13:79-84, 1996
14. Gennarelli TA, Spielman GM, Langfitt TW, et al: Influence of the type of intracranial lesion on outcome from severe head injury. A multicenter study using a new classification system. J Neurosurg 56:26-32, 1982
15. Gill R, Sibson NR, Hatfield RH, et al: A comparison of the early development of ischaemic damage following permanent middle cerebral artery occlusion in rats as assessed using magnetic resonance imaging and histology. J Cereb Blood Flow Metab 15:1-11, 1995
16. Globus MYT, Busto R, Dietrich WD, et al: Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and γ-aminobutyric acid studied by intracerebral microdialysis. J Neurochem 51:1455-1464, 1988
17. Graham DI, Adams JH, Doyle D: Ischaemic brain damage in fatal non-missile head injuries. J Neurol Sci 39:213-234, 1978
18. Graham DI, Ford I, Adams JH, et al: Ischaemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatry 52:346-350, 1989
19. Graham SH, Chen J, Lan J, et al: Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion. J Pharmacol Exp Ther 269:854-859, 1994
20. Grotta J: Safety and tolerability of the glutamate antagonist CGS19755 in acute stroke patients. Stroke 25:255, 1994 (Abstract)
21. Hagberg H, Lehmann A, Sandberg M, et al: Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments. J Cereb Blood Flow Metab 5: 413-419, 1985
22. Haselsberger K, Pucher R, Auer LM: Prognosis after acute subdural or epidural haemorrhage. Acta Neurochir 90:111-116, 1988
23. Hillered L, Hallström A, Segersvard S, et al: Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab 9:607-616, 1989
24. Inglis F, Kuroda Y, Bullock R: Glucose hypermetabolism after acute subdural hematoma is ameliorated by a competitive NMDA antagonist. J Neurotrauma 9:75-84, 1992
25. Kaplan B, Brint S, Tanabe J, et al: Temporal thresholds for neo-cortical infarction in rats subjected to reversible focal cerebral ischemia. Stroke 22:1032-1039, 1991
26. Katayama Y, Becker DP, Tamura T, et al: Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 73: 889-900, 1990
27. Klun B, Fettich M: Factors influencing the outcome in acute subdural haematoma. A review of 330 cases. Acta Neurochir 71:171-178, 1984
28. König JFR, Klippel RA: The Rat Brain. A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brain Stem. Baltimore: Williams & Wilkins, 1963
29. Kuroda Y, Bullock R: Failure of cerebral blood flow-metabolism coupling after acute subdural hematoma in the rat. Neurosurgery 31:1062-1071, 1992
30. Kuroda Y, Fujisawa H, Strebel S, et al: Effect of neuroprotective N-methyl-D-aspartate antagonists on increased intracranial pressure: studies in the rat acute subdural hematoma model. Neurosurgery 35:106-112, 1994
31. Kuroda Y, Inglis FM, Miller JD, et al: Transient glucose hyper-metabolism after acute subdural hematoma in the rat. J Neurosurg 76:471-477, 1992
32. Leach MJ, Swan JH, Eisenthal D, et al: BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke 24:1063-1067, 1993
33. Lustig HS, von Brauchitsch KL, Chan J, et al: A novel inhibitor of glutamate release reduces excitotoxic injury in vitro. Neurosci Lett 143:229-232, 1992
34. McCulloch J, Bullock R, Teasdale GM: Excitatory amino acid antagonists: opportunities for the treatment of ischaemic brain damage in man, in Meldrum BS (ed): Excitatory Amino Acid Antagonists. Oxford: Blackwell, 1991, pp 287-326
35. Meldrum BS, Swan JH, Leach MJ, et al: Reduction of glutamate release and protection against ischemic damage by BW 1003C87. Brain Res 593:1-6, 1992
36. Miller JD: Head injury and brain ischaemia - implications for therapy. Br J Anaesth 57:120-129, 1985
37. Miller JD, Bullock R, Graham DI, et al: Ischemic brain damage in a model of acute subdural hematoma. Neurosurgery 27: 433-439, 1990
38. Miller JD, Butterworth JF, Gudeman SK, et al: Further experience in the management of severe head injury. J Neurosurg 54:289-299, 1981
39. 3H]glutamate-binding sites in rat brain. J Neurosci 5:2909-2919, 1985
40. Olney JW, Labruyere J, Price MT: Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244:1360-1362, 1989
41. Olney JW, Labruyere J, Wang G, et al: NMDA antagonist neurotoxicity: mechanism and prevention. Science 254: 1515-1518, 1991
42. Osborne KA, Shigeno T, Balarsky AM, et al: Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J Neurol Neurosurg Psychiatry 50:402-410, 1990
43. Phuenpathom N, Choomuang M, Ratanalert S: Outcome and outcome prediction in acute subdural hematoma. Surg Neurol 40:22-25, 1993
44. Robertson CS, Grossman RG, Goodman JC, et al: The predictive value of cerebral anaerobic metabolism with cerebral infarction after head injury. J Neurosurg 67:361-368, 1987
45. Salvant JB Jr, Muizelaar JP: Changes in cerebral blood flow and metabolism related to the presence of subdural hematoma. Neurosurgery 33:387-393, 1993
46. Seelig JM, Becker DP, Miller JD, et al: Traumatic acute subdural hematoma. Major mortality reduction in comatose patients treated within four hours. N Engl J Med 304: 1511-1518, 1981
47. Shimada N, Graf R, Rosner G, et al: Ischemic flow threshold for extracellular glutamate increase in cat cortex. J Cereb Blood Flow Metab 9:603-606, 1989
48. Simon R, Shiraishi K: N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism. Ann Neurol 27: 606-611, 1990
49. Smith SE, Lekieffre D, Sowinski P, et al: Cerebroprotective effect of BW619C89 after focal or global cerebral ischaemia in the rat. Neuroreport 4:1339-1342, 1993
50. Stone JL, Lowe RJ, Jonasson O, et al: Acute subdural hematoma: direct admission to a trauma center yields improved results. J Trauma 26:445-450, 1986
51. Stone JL, Rifai MHS, Sugar O, et al: Subdural hematoma. I. Acute subdural hematoma: progress in definition, clinical pathology, and therapy. Surg Neurol 19:216-231, 1983
52. Wilberger JE Jr, Harris M, Diamond DL: Acute subdural hematoma: morbidity, mortality, and operative timing. J Neurosurg 74:212-218, 1991