Unorthodox antibiotic combinations including ciprofloxacin against high-level gentamicin resistant enterococci

Journal of Antimicrobial Chemotherapy

Volumn 37, Issue 4, 1996, Pages 727-736

  Tripodi, M F ^a   Utili, R ^a   Rambaldi, A ^a   Locatelli, A ^a   Rosario, P ^a   Florio, A ^a   Ruggiero, G ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; TEICOPLANIN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; ENTEROCOCCUS; ENTEROCOCCUS CASSELIFLAVUS; ENTEROCOCCUS FAECALIS; GRAM NEGATIVE INFECTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

AMPICILLIN; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; CIPROFLOXACIN; DRUG COMBINATIONS; DRUG RESISTANCE, MICROBIAL; DRUG THERAPY, COMBINATION; ENTEROCOCCUS; GENTAMICINS; HUMANS; MICROBIAL SENSITIVITY TESTS; PENICILLINS; SULFAMETHOXAZOLE; TRIMETHOPRIM;

EID: 0029976145     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.4.727     Document Type: Article

References (27)

1. Centers for Diseases Control. (1986). Nosocomial infection surveillance, 1984. Morbidity and Mortality Weekly Report 35, Suppl. ISS, 17SS-29SS.
2. Clark, N.C., Cooksey, R.C., Hill, B.C., Swenson, J.M. & Tenover, F.C. (1993). Characterization of glycopeptide-resistant enterococci from U.S. hospitals Antimicrobial Agents and Chemotherapy 37, 2311-17.
3. Eliopoulos, G.M., Willey, S., Murray, B.E. & Moellering, R.C. (1989). Ciprofloxacin in experimental endocarditis due to a beta-lactamase-producing, highly gentamicin-resistant strain of Enterococcus faecalis. Reviews of Infectious Diseases 11, Suppl. 5, S1210-11.
4. Fernandez-Guerrero, M., Rouse, M.S., Henry, N.K., Geraci, J.E. & Wilson, W.R. (1987). In vitro and in vivo activity of ciprofloxacin against enterococci isolated from patients with infective endocarditis. Antimicrobial Agents and Chemotherapy 31, 430-3.
5. Grayson, L.M., Thauvin-Eliopoulos, C., Eliopoulos, G.M., Yao, J.D.C., De Angelis, D.V., Walton, L. et al (1990). Failure of trimethoprim-sulphamethoxazole therapy in experimental enterococcal endocarditis. Antimicrobial Agents and Chemotherapy 34, 1792-94.
6. Grim, H. (1985). Antibacterial activity of 19 antimicrobial agents and kill kinetics of ciprofloxacin plus ampicillin against gentamicin resistant and high-level resistant enterococci. In Recent Advances in Chemotherapy, Antimicrobial Section 2. Proceedings of the Fourteenth International Congress of Chemotherapy, Kyoto, Japan, 1985 (Ishigami, J., Ed.), pp. 1571-2. University of Tokyo Press, Tokyo.
7. Haller, I. (1987). Evaluation of ciprofloxacin alone and in combination with other antibiotics in a murine model of thigh muscle infection. American Journal of Medicine 82, 76-9.
8. Hamilton-Miller, J.M.T. (1989). Antibiotic treatment of enterococcal infection. Antimicrobial Agents and Chemotherapy 33, 989.
9. Hayden, M.K., Koenig, G.I. & Trenholme, G.M. (1994). Bactericidal activities of antibiotics against vancomycin-resistant Enterococcus faecium blood isolates and synergistic activities of combinations. Antimicrobial Agents and Chemotherapy 38, 1225-9.
10. Hindler, J.A. & Sahm, D.F. (1992). Controversies and confusion regarding antimicrobial susceptibility testing of enterococci. Antimicrobic Newsletter 8, 65-74.
11. Landman, D., Mobarakai, N.K. & Quale, J.M. (1993). Novel antibiotic regimen against Enterococcus faecium resistant to ampicillin, vancomycin, and gentamicin. Antimicrobial Agents and Chemotherapy 37, 1904-8.
12. Lipman, M. & Silva, J. (1989). Endocarditis due to Streptococcus faecalis with high-level resistance to gentamicin. Reviews of Infectious Diseases 11, 325-8.
13. Moellering, R.C. (1991). The enterococcus: a classic example of the impact of antimicrobial resistance on therapeutic options. Journal of Antimicrobial Chemotherapy 28, 1-12.
14. Moody, J.A., Peterson, L.R. & Gerding, D.N. (1985). In vitro activity of ciprofloxacin combined with azlocillin. Antimicrobial Agents and Chemotherapy 28, 849-50.
15. National Committee for Clinical Laboratory Standards (1993). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard M7-A3. NCCLS, Villanova, PA.
16. Sahm, D.F. & Koburov, G.T. (1989). In vitro activities of quinolones against enterococci resistant to penicillin-aminoglycoside synergy. Antimicrobial Agents and Chemotherapy 33, 71-7.
17. Schaberg, D.R., Dillon, W.I., Terpenning, M.S., Robinson, K.A., Bradley, S.F. & Kauffman, C.A. (1992). Increasing resistance of enterococci to ciprofloxacin. Antimicrobial Agents and Chemotherapy 36, 2533-5.
18. Smyth, G.E., Stevens, P.J., Holliman, R. (1989). Prevalence and susceptibility of highly gentamicin resistant Enterococcus faecalis in a south London teaching hospital. Journal of Antimicrobial Chemotherapy 23, 633-9.
19. Thauvin, C., Eliopoulos, G.M., Willey, S., Wennersten, C. & Moellering, R.C. (1987). Continuous-infusion ampicillin therapy of enterococcal endocarditis in rats. Antimicrobial Agents and Chemotherapy 31, 139-43.
20. Tripodi, M.F., Rambaldi, A., Utili, R., Rosario, P., Attanasio, V., Locatelli, A. et al. (1995). Resistance to aminoglycosides and other antibiotics among clinical isolates of Enterococcus spp. Microbiologica 18, 319-24.
21. Tripodi, M.F., Utili, R., Rambaldi, A., Attanasio, V., Rosario, P., Locatelli, A. et al. (1993). Effetto in vitro della ciprofioxacina associata ad altri antibiotici verso enterococchi ad elevata gentamicino-resistenza. In Program and Abstracts of the XXVII Congresso Nationale della Società Italiana di Malattie Infettive e Parassitarie, Florence, Italy, 1993, Abstract p. 275.
22. Unal, S., Flokowitsch, J., Müllen, D.L., Preston, D.A. & Nicas, T.I. (1993). In vitro synergy and mechanism of interaction between vancomycin and ciprofloxacin against enterocococcal isolates. Journal of Antimicrobial Chemotherapy 31, 711-23.
23. Watanakunakorn, C. (1992). Rapid increase in the prevalence of high-level aminoglycoside resistance among enterococci isolated from blood cultures during 1989-1991. Journal of Antimicrobial Chemotherapy 30, 289-93.
24. Whitman, M.S., Pitsakis, P.G., Zausner, A., Livornese, L.L., Osborne, A.J., Johnson, C.C. et al. (1993). Antibiotic treatment of experimental endocarditis due to vancomycin- and ampicillin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy 37, 2069-73.
25. Working Party Report of the British Society for Antimicrobial Chemotherapy (1991). A guide to sensitivity testing. Journal of Antimicrobial Chemotherapy 27, Suppl. D, 1-50.
26. Yao, J.D.C., Thauvin-Eliopoulos, C., Eliopoulos, G.M. & Moellering, R.C. (1990). Efficacy of teicoplanin in two dosage regimens for experimental endocarditis caused by a β-lactamase producing strain of Enterococcus faecalis with high-level resistance to gentamicin. Antimicrobial Agents and Chemotherapy 34, 827-30.
27. Zervos, M.J., Bacon, A.E., Patterson, I.E., Schaberg, D.R. & Kauffman, C.A. (1988). Enterococcal superinfection in patients treated with ciprofloxacin. Journal of Antimicrobial Chemotherapy 21, 113-5.