Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: Deletion of the CCNC gene in human tumors

Genomics

Volumn 32, Issue 2, 1996, Pages 253-259

  Li, Haimin ^a   Lahti, Jill M ^a   Valentine, Marcus ^a   Saito, Midori ^b   Reed, Steven I ^b   Look, A Thomas ^a   Kidd, Vincent J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER GENETICS; CHROMOSOMAL LOCALIZATION; CHROMOSOME 19Q; CHROMOSOME 6Q; CHROMOSOME TRANSLOCATION 2; CHROMOSOME TRANSLOCATION 6; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE LOCATION; GENE STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0029975998     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0112     Document Type: Article

References (48)

1. Caldas, C., Hahn, S. A., daCosta, L. T., Redston, M. S., Schutte, M., Seymour, A. B., Weinstein, C. L., Hruban, R. H., Yeo, C. J., and Kern, S. E. (1994). Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nature Genet. 8: 27-32.
2. Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., and Beach, D. H. (1995). Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenet. Cell Genet. 69: 190-192.
3. Draetta, G., Luca, F., Westendorf, J., Brizuela, L., Ruderman, J., and Beach, D. (1989). Cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF. Cell 56: 829-838.
4. 1-S phase protein kinase. Science 257: 1958-1961.
5. Eipers, P. G., Barnoski, B. L., Han, J., Carroll, A. J., and Kidd, V. J. (1991). Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a highly related sequence to chromosome 15. Genomics 11: 621-629.
6. Eipers, P. G., Lahti, J. M., and Kidd, V. J. (1992). Structure and expression of the human p58clk-1 protein kinase chromosomal gene. Genomics 13: 613-621.
7. Hussussian, C. J., Struewing, J. P., Goldstein, A. M., Higgins, P. A. T., Ally, D. S., Sheahan, M. D., Clark, W. H., Tucker, M. A., and Dracopoli, N. C. (1994). Germline p16 mutations in familial melanoma. Nature Genet. 8: 15-21.
8. Kamb, A., Gruis, N.-A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavtigian, S.-V., Stockert, E., Day, R.-S. III, Johnson, B.-E., and Skolnick, M.-H. (1994a). A cell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436-440.
9. Kamb, A., Shattuck-Eidens, D., Eeles, R., Liu, Q., Gruis, N. A., Ding, W., Hussey, C., Tran, T., Miki, Y., Weaver-Feldhaus, J., McClure, M., Aitken, J. F., Anderson, D. E., Bergman, W., Frants, R., Goldgar, D. E., Green, A., MacLennan, R., Martin, N. G., Meyer, L. J., Youl, P., Zone, J. J., Skolnick, M. H., and Cannon-Albright, L. A. (1994b). Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature Genet. 8: 22-26.
10. Kamps, M. P., Look, A. T., and Baltimore, D. (1991). The human t(1;19) translocation in pre-B-ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials. Genes Dev. 5: 358-368.
11. 2-M transition. EMBO J. 12: 65-74.
12. Knoblich, J. A., Sauer, K., Jones, L., Richardson, H., Saint, R., and Lehner, C. F. (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 77: 107-120.
13. Koff, A., Giordano, A., Desai, D., Yamashita, K., Harper, J. W., Elledge, S., Nishimoto, T., Morgan, D. O., Franza, B. R., and Roberts, J. M. (1992). Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257: 1689-1694.
14. Koh, J., Enders, G. H., Dynlacht, B. D., and Harlow, E. (1995). Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature 375: 506-510.
15. Kowalczyk, J. R., Grossi, M., and Sandberg, A. A. (1985). Cytogenetic findings in childhood acute lymphoblastic leukemia. Cancer Genet. Cytogenet. 15: 47-60.
16. Lehner, C. F., and O'Farrell, P. H. (1989). Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell 56: 957-968.
17. Lehner, C. F., and O'Farrell, P. H. (1990). The roles of Drosophila cyclins A and B in mitotic control. Cell 61: 535-547.
18. Leopold, P., and O'Farrell, P. H. (1991). An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins. Cell 66: 1207-1216.
19. Lew, D. J., Dulic, V., and Reed, S. I. (1991). Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 66: 1197-1206.
20. Liao, S-M., Zhang, J., Jeffery, D. A., Koleske, A. J., Thompson, C. M., Chao, D. M., Viljoen, M., vanVuuren, H. J. J., and Young, R. A. (1995). A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374: 193-196.
21. Maller, J. L. (1991). Mitotic control. Curr. Opin. Cell Biol. 3: 269-275.
22. Minshull, J., Golsteyn, R., Hill, C. S., and Hunt, T. (1990). The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J. 9: 2865-2875.
23. Mount, S. M. (1982). A catalogue of splice junction sequences. Nucleic Acids Res. 10: 459-472.
24. Nurse, P. (1990). Universal control mechanism regulating onset of M-phase. Nature 344: 503-508.
25. O'Neill, E. M., and O'Shea, E. K. (1995). Cyclins in initiation. Nature 374: 121-122.
26. 1 in mammalian fibroblasts. Science 259: 1908-1911.
27. 1-to-S phase transition. Mol. Cell. Biol. 15: 2612-2624.
28. Ohyashiki, K., Ohyashiki, J. H., Kinniburgh, A. J., Toyama, K., Ito, H., Minowada, J., and Sandberg, A. A. (1989). myb oncogene in human hematopoietic neoplasia with 6q-anomaly. Cancer Genet. Cytogenet. 33: 83-95.
29. Pagano, M., Pepperkok, R., Verde, F., Ansorge, W., and Draetta, G. (1992). Cyclin A is required at two points in the human cell cycle. EMBO J. 11: 961-971.
30. INK4/MTS1 tumour suppressor gene product. EMBO J. 14: 503-511.
31. Kip1 gene to 12p13 and its analysis in leukemias. Cancer Res. 55: 1206-1210.
32. Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res. 55: 1211-1214.
33. Prigogina, E. L., Puchkova, G. P., and Mayakova, S. A. (1988). Non-random chromosomal abnormalities in acute lymphoblastic leukemia of childhood. Cancer Genet. Cytogenet. 32: 183-195.
34. INK4 function. Nature Genet. 10: 114-116.
35. Reed, J. A., Loganzo, F., Shea, C. R., Walker, G. J., Flores, J. F., Glendening, J. M., Bogdany, J. K., Shiel, M. J., Haluska, F. G., Fountain, J. W., and Albino, A. P. (1995). Loss of expression of the p16/Cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression. Cancer Res. 55: 2713-2718.
36. Resnitzky, D., Gossen, M., Bujard, H., and Reed, S. I. (1994). Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol. 14: 1669-1679.
37. Rosenblatt, J., Gu, Y., and Morgan, D. O. (1992). Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc. Natl. Acad. Sci. USA 89: 2824-2828.
38. Roy, L. M., Swenson, K. I., Walker, D. H., Gabrielli, B. G., Li, R. S., Piwnica Worms, H., and Maller, J. L. (1991). Activation of p34cdc2 kinase by cyclin A. J. Cell Biol. 113: 507-514.
39. Sherr, C. J. (1993). Mammalian G1 cyclins. Cell 73: 1059-1065.
40. Sherr, C. J. (1994). G1 phase progression: Cycling on cue. Cell 79: 551-555.
41. 1 cyclin-dependent kinases. Genes Dev. 9: 1149-1163.
42. Solomon, M. J., Glotzer, M., Lee, T. H., Philippe, M., and Kirschner, M. W. (1990). Cyclin activation of p34cdc2. Cell 63: 1013-1024.
43. Spinardi, L., Mazars, R., and Theilet, C. (1991). Protocols for an improved detection of point mutations by SSCP. Nucleic Acids Res. 19: 4009.
44. Tassan, J-P., Jaquenoud, M., Leopold, P., Schultz, S. J., and Nigg, E. A. (1995). Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proc. Natl. Acad. Sci. USA 92: 8871-8875.
45. Walker, D. H., and Maller, J. L. (1991). Role for cyclin A in the dependence of mitosis on completion of DNA replication. Nature 354: 314-317.
46. Xiang, J., Lahti, J. M., Grenet, J., Easton, J., and Kidd, V. J. (1994). Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms. J. Biol. Chem. 269: 15786-15794.
47. Xiong, Y., Zhang, H., and Beach, D. (1993). Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 7: 1572-1583.
48. Zindy, F., Lamas, E., Chenivesse, X., Sobczak, J., Wang, J., Fesquet, D., Henglein, B., and Brechot, C. (1992). Cyclin A is required in S phase in normal epithelial cells. Biochem. Biophys. Res. Commun. 82: 1144-1154.