Application of 2-hydroxypropyl-β-cyclodextrin in the assay of acyl-CoA:Cholesterol acyltransferase and neutral and acid cholesterol ester hydrolases

Lipids

Volumn 31, Issue 3, 1996, Pages 323-329

  Liza, Mariana ^a   Romero, José R ^a   Chico, Yolanda ^a   Fresnedo, Olatz ^a   Ochoa, Begoña ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ACYL COENZYME A; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTERASE; CYCLODEXTRIN;

ARTICLE; CATALYSIS; CELL FRACTIONATION; CHOLESTEROL SYNTHESIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LOCALIZATION; LIPOPHILICITY; LIVER CELL; LIVER MITOCHONDRION;

AMIDES; ANIMALS; BETA-CYCLODEXTRINS; CELL FRACTIONATION; CHOLESTEROL; CHOLESTEROL ESTERASE; CYCLODEXTRINS; CYTOPLASM; ENZYME ACTIVATION; ENZYME INHIBITORS; HYDROXYCHOLESTEROLS; KINETICS; LYSOSOMES; MICROSOMES, LIVER; MITOCHONDRIA, LIVER; ORGANOSILICON COMPOUNDS; RATS; SODIUM FLUORIDE; SOLUBILITY; STEROL O-ACYLTRANSFERASE;

EID: 0029975992     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02529879     Document Type: Article

References (22)

1. Uekama, K., and Otagiri, M. (1987) Cyclodextrms in Drug Carrier Systems, CRC Crit. Rev. Ther. Drug Carrier Syst. 3, 1-40.
2. Pitha, J., Irie, T., Sklar, P.B., and Nye, J.S. (1988) Drug Solubilizers to Aid Pharmacologists: Amorphous Cyclodextrin Derivatives, Life Sci. 43, 493-502.
3. Yaksh, T.L., Jang, J., Nishiuchi, Y., Braun, K.P., Ro, S., and Goodman, M. (1991) The Utility of 2-Hydroxypropyl-β-Cyclodextrin as a Vehicle for the Intracerebral and Intrathecal Administration of Drugs, Life Sci. 48, 623-633.
4. De Caprio, J., Yun, J., and Javitt, N.B. (1992) Bile Acid and Sterol Solubilization in 2-Hydroxyproyl-β-Cyclodextrin, J. Lipid Res. 33, 441-443
5. Martin, K.O., Budai, K., and Javitt. N.B. (1993) Cholesterol and 27-Hydroxycholesterol 7α-Hydroxylation: Evidence for Two Different Enzymes, J. Lipid Res. 34, 581-588.
6. Petrack, B., and Latario, B.J. (1993) Synthesis of 27-Hydroxycholesterol in Rat Liver Mitocondria: HPLC Assay and Marked Activation by Exogenous Cholesterol, J. Lipid Res. 34, 643-649.
7. Hashimoto, S., and Fogelman, A.M. (1980) Smooth Microsomes: A Trap for Cholesteryl Esters Formed in Hepatic Microsomes, J. Biol. Chem. 255, 8678-8684.
8. Suckling, K.E., and Stange, E. (1985) Role of Acyl-CoA:Cholesterol Acyltransferase in Cellular Cholesterol Metabolism, J. Lipid Res. 26, 647-671.
9. Billheimer, J.T., Tavani, D., and Ness, W.R. (1981) Effect of a Dispersion of Cholesterol in Triton WR-1339 on Acyl-CoA:Cholesterol Acyltransferase in Rat Liver Microsomes, Anal. Biochem. 111, 331-335.
10. Brecher, P., Chobanian, J., Small, D.M., and Chobanian, A.V. (1976) The Use of Phospholipid Vesicles for in vitro Studies on Cholesterol Ester Hydrolases, J. Lipid Res. 17, 239-247.
11. Hajjar, D.P., Minick, C.R., and Fowler, S. (1983) Arterial Neutral Cholesterol Esterase. A Homone-Sensitive Enzyme Distinct from Lysosomal Cholesteryl Esterase, J. Biol. Chem. 258, 192-198.
12. Ruiz, M,B., Ochoa, B., and Lacort, M. (1990) Glucagon and Dibutyryl CyclicAMP-Produced Inhibition of Cholesterol Ester Hydrolase in Isolated Rat Hepatocytes, J. Biochem. 107, 476-479.
13. Polokoff, M.A., Coleman, R.A., and Bell, R.M. (1979) Evidence That Cholic Acid CoA Ligase is Located Asymmetrically on the Cytoplasmic Surface of Hepatic Microsomal Vesicles, J. Lipid Res. 20, 17-21.
14. Martínez, M.J., Ruiz, J.I., Lacort, M., and Ochoa, B. (1991) Diurnal Variations of Rat Liver Enzymes Catalyzing Cholesterol Ester Hydrolysis, Biochim. Biophys. Acta 1085, 106-111.
15. Bradford, M.M. (1976) A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding, Anal. Biochem. 72, 248-254.
16. Botham, K.M., Martínez, M.J., and Ochoa, B. (1993) Cholesteryl Ester Synthesis and Hydrolysis in the Rat Mammary Gland During Pregnancy and Lactation, J. Biochem, 114, 415-420.
17. Folch, J., Lees, M., and Sloane-Stanley, G.N. (1957) A Simple Method for the Isolation and Purification of Total Lipids from Animal Tissues, J. Biol. Chem. 226, 497-509.
18. Harrison, E.H. (1988) Bile Salt-Dependent Neutral Cholesteryl Ester Hydrolase of Rat Liver: Possible Relationship with Pancreatic Cholesteryl Ester Hydrolase, Biochim. Biophys. Acta 963, 28-34.
19. Ross, R., Go, H., Heider, J., and Rothblath, G. (1984) Selective Inhibition of Acyl-CoA:Cholesterol Acyltransferase by Compound 58-035, J. Biol. Chem. 259, 815-823.
20. Lichtenstein, A., and Brecher. P. (1983) Esterification of Cholesterol and 25-Hydroxycholesterol by Rat Liver Microsomes, Biochim. Biophys. Acta 751, 340-348.
21. Billheimer, J.T., Cromley, D.A., and Kempner, E.S. (1990) The Functional Size of Acyl-CoA:Cholesterol Acyltransferase and Acyl-CoA Hydrolase as Determined by Radiation Inactivation, J. Biol. Chem. 265, 8632-8635.
22. Fernández, C.J., Lacort. M., Gandarias, J.M., and Ochoa, B. (1987) Topological Studies on Rat Liver Microsomal Cholesterol Ester Hydrolase. Biochem. Biophys. Res. Commun. 146, 1212-1217.