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Volumn 9, Issue 2, 1996, Pages 177-183

Liver injury due to iron overload in thalassemia: Histopathologic and ultrastructural studies

Author keywords

Histopathology; Iron overload; Liver injury; Thalassemia; Ultrastructure

Indexed keywords

HEMOGLOBIN H; HEMOSIDERIN;

EID: 0029975971     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00144623     Document Type: Article
Times cited : (46)

References (41)
  • 1
    • 0021934763 scopus 로고
    • Hepatic mitochondrial oxidative metabolism in rats with chronic dietary iron overload
    • Bacon BR, Park CH, Brittenham GM, O'Neill R, Tavill AS. 1985 Hepatic mitochondrial oxidative metabolism in rats with chronic dietary iron overload. Hepatology 5, 789-797.
    • (1985) Hepatology , vol.5 , pp. 789-797
    • Bacon, B.R.1    Park, C.H.2    Brittenham, G.M.3    O'Neill, R.4    Tavill, A.S.5
  • 2
    • 0015947937 scopus 로고
    • Long-term chelation therapy in thalassemia major: Effect on liver iron concentration, liver histology and clinical progress
    • Barry M, Flynn DM, Letsky EA, Risdon RA. 1974 Long-term chelation therapy in thalassemia major: effect on liver iron concentration, liver histology and clinical progress. Br Med J 2, 16-20.
    • (1974) Br Med J , vol.2 , pp. 16-20
    • Barry, M.1    Flynn, D.M.2    Letsky, E.A.3    Risdon, R.A.4
  • 3
    • 0022656390 scopus 로고
    • Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis
    • Basset ML, Halliday JW, Powell LW. 1986 Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology 6, 24-29.
    • (1986) Hepatology , vol.6 , pp. 24-29
    • Basset, M.L.1    Halliday, J.W.2    Powell, L.W.3
  • 4
    • 0014093547 scopus 로고
    • Pathology of abnormal hemoglobin disease seen in Thailand. I Pathology of β-thalassemia/hemoglobin E disease
    • Bhamarapravali N, Na-Nakorn S, Wasi P, Tuchinda S. 1967 Pathology of abnormal hemoglobin disease seen in Thailand. I Pathology of β-thalassemia/hemoglobin E disease. Am J. Clin Pathol 47, 745-758.
    • (1967) Am J. Clin Pathol , vol.47 , pp. 745-758
    • Bhamarapravali, N.1    Na-Nakorn, S.2    Wasi, P.3    Tuchinda, S.4
  • 5
    • 0014685740 scopus 로고
    • Histopathologic studies in thalassemia minor and intermedia
    • Block M. 1969 Histopathologic studies in thalassemia minor and intermedia. Ann NY Acad Sci 20, 126-147.
    • (1969) Ann NY Acad Sci , vol.20 , pp. 126-147
    • Block, M.1
  • 6
    • 0006268197 scopus 로고
    • Thalassemia minor complicated by excessive iron storage
    • Bowdler AJ, Huehns ER. 1963 Thalassemia minor complicated by excessive iron storage. Br J Haematol 9, 13-24.
    • (1963) Br J Haematol , vol.9 , pp. 13-24
    • Bowdler, A.J.1    Huehns, E.R.2
  • 7
    • 9044243039 scopus 로고
    • Lipid peroxidation stimulates collagen gene expression. a common pathway for fibrogenesis?
    • Abstr.
    • Chojkier M, Solis-Herruzo JA, Brenner DA. 1988 Lipid peroxidation stimulates collagen gene expression. A common pathway for fibrogenesis? Gastroenterology 94, 529 (Abstr.).
    • (1988) Gastroenterology , vol.94 , pp. 529
    • Chojkier, M.1    Solis-Herruzo, J.A.2    Brenner, D.A.3
  • 8
    • 0021225166 scopus 로고
    • Depletion of excessive liver iron stores with desferrioxamine
    • Cohen A, Martin M, Schwartz E. 1984 Depletion of excessive liver iron stores with desferrioxamine. Br J Haematol 58, 369-373.
    • (1984) Br J Haematol , vol.58 , pp. 369-373
    • Cohen, A.1    Martin, M.2    Schwartz, E.3
  • 9
    • 0002054429 scopus 로고
    • Cellular injury and adaptation
    • Cotran RS, Kumar V, Robbins SL, eds. Philadelphia: W. B. Saunders
    • Cotran RS, Kumar V, Robbins SL. 1989 Cellular injury and adaptation. In: Cotran RS, Kumar V, Robbins SL, eds. Robbins Pathologic Basis of Disease. Philadelphia: W. B. Saunders.
    • (1989) Robbins Pathologic Basis of Disease
    • Cotran, R.S.1    Kumar, V.2    Robbins, S.L.3
  • 10
    • 0014297319 scopus 로고
    • Liver biopsy in diagnosis of hemochromatosis
    • Craig JR. 1968 Liver biopsy in diagnosis of hemochromatosis. Am J Med 44, 837-841.
    • (1968) Am J Med , vol.44 , pp. 837-841
    • Craig, J.R.1
  • 11
    • 0022778336 scopus 로고
    • Return of the radicals
    • Editorial. 1986 Return of the radicals. Human Pathol 17, 869-870.
    • (1986) Human Pathol , vol.17 , pp. 869-870
  • 13
    • 0021186609 scopus 로고
    • Iron overload and lysosomal stability in β-thalassemia intermedia and trait: Correlation between serum ferritin and serum N-acetyl-β-D-glucosaminidase levels
    • Frigerio R, Mela Q, Passiu G et al. 1984 Iron overload and lysosomal stability in β-thalassemia intermedia and trait: correlation between serum ferritin and serum N-acetyl-β-D-glucosaminidase levels. Scand J Haematol 33, 252-255.
    • (1984) Scand J Haematol , vol.33 , pp. 252-255
    • Frigerio, R.1    Mela, Q.2    Passiu, G.3
  • 14
    • 9244241570 scopus 로고
    • Changes associated with the accumulation of excessive amounts of iron in certain organs of the rat
    • Golberg L, Smith JP. 1958 Changes associated with the accumulation of excessive amounts of iron in certain organs of the rat. Br J Exp Pathol 39, 59.
    • (1958) Br J Exp Pathol , vol.39 , pp. 59
    • Golberg, L.1    Smith, J.P.2
  • 16
    • 0024419988 scopus 로고
    • Mechanism of iron toxicity and its possible role in red cell membrane damage
    • Hershko C. 1989 Mechanism of iron toxicity and its possible role in red cell membrane damage. Semin Haematol 26, 277-285.
    • (1989) Semin Haematol , vol.26 , pp. 277-285
    • Hershko, C.1
  • 17
    • 0017300934 scopus 로고
    • The liver thalassemia major: Ultrastructural observations
    • Amsterdam: Experta Medica
    • Iancu TC, Neustein HB, Landing BH. 1977a The liver thalassemia major: Ultrastructural observations. In: Iron Metabolism, Ciba Foundation Symp. 51. Amsterdam: Experta Medica; 293-309.
    • (1977) Iron Metabolism, Ciba Foundation Symp. , vol.51 , pp. 293-309
    • Iancu, T.C.1    Neustein, H.B.2    Landing, B.H.3
  • 18
    • 0017709789 scopus 로고
    • Pathogenetic mechanisms in hepatic cirrhosis of thalassemia major: Light and electron microscopic studies
    • Somers SC, ed. New York: Appleton Century Crofts
    • Iancu TC, Landing BH, Neustein HB. 1977b Pathogenetic mechanisms in hepatic cirrhosis of thalassemia major: light and electron microscopic studies. In: Somers SC, ed. Pathology Annual. New York: Appleton Century Crofts; 171-200.
    • (1977) Pathology Annual , pp. 171-200
    • Iancu, T.C.1    Landing, B.H.2    Neustein, H.B.3
  • 20
    • 0000345583 scopus 로고
    • Effect of iron loading upon the formation of collagen in the hepatic injury induced by carbon tetrachloride
    • Kent G, Volini FI, Minick OT, Orfei E, De La Huerga J. 1964 Effect of iron loading upon the formation of collagen in the hepatic injury induced by carbon tetrachloride. Am J Pathol 45, 129-155.
    • (1964) Am J Pathol , vol.45 , pp. 129-155
    • Kent, G.1    Volini, F.I.2    Minick, O.T.3    Orfei, E.4    De La Huerga, J.5
  • 21
    • 85047678275 scopus 로고
    • Role of chronic hepatitis in development of thalassemic liver disease
    • Masera G, Jean G, Gazzola G, Novakova M. 1976 Role of chronic hepatitis in development of thalassemic liver disease. Arch Dis Child 51, 680-685.
    • (1976) Arch Dis Child , vol.51 , pp. 680-685
    • Masera, G.1    Jean, G.2    Gazzola, G.3    Novakova, M.4
  • 23
    • 0022368621 scopus 로고
    • Survival and causes of death in cirrhotic and noncirrhotic patients with primary hemochromatosis
    • Niederau C, Fischer R, Sonnenberg A, Stremmelw, Trampisch HJ, Strohmeyer G. 1985 Survival and causes of death in cirrhotic and noncirrhotic patients with primary hemochromatosis. N Engl J Med 313, 1256-1262.
    • (1985) N Engl J Med , vol.313 , pp. 1256-1262
    • Niederau, C.1    Fischer, R.2    Sonnenberg, A.3    Stremmelw4    Trampisch, H.J.5    Strohmeyer, G.6
  • 24
    • 0017183672 scopus 로고
    • Splenectomy iron overload and liver cirrhosis in β-thalassemia major
    • Okon E, Levij IS, Rachmilewitz EA. 1976 Splenectomy iron overload and liver cirrhosis in β-thalassemia major. Acta Hematol 56, 142-150.
    • (1976) Acta Hematol , vol.56 , pp. 142-150
    • Okon, E.1    Levij, I.S.2    Rachmilewitz, E.A.3
  • 25
    • 0014262515 scopus 로고
    • Effect of iron loading on the hepatic injury induced by ethionine. A re-evaluation
    • Orfel E, Volini FI, Madera-Orsini F, Minick T, Kent G. 1968 Effect of iron loading on the hepatic injury induced by ethionine. A re-evaluation. Am J Pathol 52, 547-567.
    • (1968) Am J Pathol , vol.52 , pp. 547-567
    • Orfel, E.1    Volini, F.I.2    Madera-Orsini, F.3    Minick, T.4    Kent, G.5
  • 27
    • 0017253603 scopus 로고
    • Lipid membrane peroxidation in β-thalassemia major
    • Rachnilewitz EA, Lubin BH, Shohet SB. 1976 Lipid membrane peroxidation in β-thalassemia major. Blood 47, 495-505.
    • (1976) Blood , vol.47 , pp. 495-505
    • Rachnilewitz, E.A.1    Lubin, B.H.2    Shohet, S.B.3
  • 28
    • 0009639479 scopus 로고
    • Acute intestinal iron intoxication. II Metabolic, respiratory, and circulatory effects of absorbed iron salts
    • Reissmann KR, Coleman TJ. 1955 Acute intestinal iron intoxication. II Metabolic, respiratory, and circulatory effects of absorbed iron salts. Blood 10, 46-51.
    • (1955) Blood , vol.10 , pp. 46-51
    • Reissmann, K.R.1    Coleman, T.J.2
  • 29
    • 0018095305 scopus 로고
    • The iron-loaded cell. the cytopathology of iron storage
    • Richter GW. 1978 The iron-loaded cell. The cytopathology of iron storage. Am J Pathol 91, 363-396.
    • (1978) Am J Pathol , vol.91 , pp. 363-396
    • Richter, G.W.1
  • 30
    • 0016808878 scopus 로고
    • Transfusional iron overload: The relationship between tissue iron concentration and hepatic fibrosis in thalassemia
    • Risdon RA, Barry M, Flynn DM. 1975 Transfusional iron overload: the relationship between tissue iron concentration and hepatic fibrosis in thalassemia. J Pathol 116, 83-95.
    • (1975) J Pathol , vol.116 , pp. 83-95
    • Risdon, R.A.1    Barry, M.2    Flynn, D.M.3
  • 33
    • 0011732051 scopus 로고
    • Hemochromatosis: Iron metabolism and the iron overload syndromes
    • Zakim D, Boyer TD, eds. Philadelphia: W. B. Saunders
    • Tavill AS, Bacon BR. 1990 Hemochromatosis: iron metabolism and the iron overload syndromes. In: Zakim D, Boyer TD, eds. Hepatology: A Textbook of Liver Disease. Philadelphia: W. B. Saunders; 1273-1299.
    • (1990) Hepatology: A Textbook of Liver Disease , pp. 1273-1299
    • Tavill, A.S.1    Bacon, B.R.2
  • 34
    • 0024985439 scopus 로고
    • Iron and the liver: Genetic hemochromatosis and other hepatic iron overload disorders
    • Popper H, Schaffner F, eds. Philadelphia: W. B. Saunders
    • Tavill AS, Sharma BK, Bacon BR. 1990 Iron and the liver: Genetic hemochromatosis and other hepatic iron overload disorders. In: Popper H, Schaffner F, eds. Progress in Liver Diseases. Vol IX. Philadelphia: W. B. Saunders; 281-305.
    • (1990) Progress in Liver Diseases , vol.9 , pp. 281-305
    • Tavill, A.S.1    Sharma, B.K.2    Bacon, B.R.3
  • 35
    • 0015863070 scopus 로고
    • The relationship of intracellular pathways of iron metabolism of cellular iron overload and the iron storage diseases. Cell sap and cytocavitary network pathways in relation to lysomsomal storage and turnover of iron macromolecules
    • Trump BF, Valigorsky JM, Arstila AU, Mergner WJ, Kinney TD. 1973 The relationship of intracellular pathways of iron metabolism of cellular iron overload and the iron storage diseases. Cell sap and cytocavitary network pathways in relation to lysomsomal storage and turnover of iron macromolecules. Am J Pathol 72, 295-324.
    • (1973) Am J Pathol , vol.72 , pp. 295-324
    • Trump, B.F.1    Valigorsky, J.M.2    Arstila, A.U.3    Mergner, W.J.4    Kinney, T.D.5
  • 36
    • 0018526515 scopus 로고
    • Serum iron in thalassemia and the effect of splenetomy
    • Wasi P, Pravatmuang P. 1979 Serum iron in thalassemia and the effect of splenetomy. J Med Ass Thailand 62, 532-537.
    • (1979) J Med Ass Thailand , vol.62 , pp. 532-537
    • Wasi, P.1    Pravatmuang, P.2
  • 37
    • 0003917943 scopus 로고
    • The iron loading anemias
    • Martell AE, Anderson FW, Badman DG, eds. New York: Elseiver North Holland
    • Weatheral DJ. 1981 The iron loading anemias. In: Martell AE, Anderson FW, Badman DG, eds. Development of Iron Chelators in Clinical Use. New York: Elseiver North Holland.
    • (1981) Development of Iron Chelators in Clinical Use
    • Weatheral, D.J.1
  • 40
    • 0021368971 scopus 로고
    • Liver damage in disorders of iron overload
    • Wheby MS. 1984 Liver damage in disorders of iron overload. Arch Intern Med 144, 621-622.
    • (1984) Arch Intern Med , vol.144 , pp. 621-622
    • Wheby, M.S.1
  • 41
    • 0002160955 scopus 로고
    • The effect of long survival on the pathology of thalassemia major
    • Witzleben CL, Wyatt JP. 1961 The effect of long survival on the pathology of thalassemia major. J Pathol Bacterial 82, 1-12.
    • (1961) J Pathol Bacterial , vol.82 , pp. 1-12
    • Witzleben, C.L.1    Wyatt, J.P.2


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