The sre gene (ORF469) encodes a site-specific recombinase responsible for integration of the R4 phage genome

Journal of Bacteriology

Volumn 178, Issue 11, 1996, Pages 3374-3376

  Matsuura, Manabu ^a   Noguchi, Takahiko ^a   Yamaguchi, Daisuke ^a   Aida, Tokujiro ^a   Asayama, Munehiko ^a   Takahashi, Hideo ^b   Shirai, Makoto ^a  

^a IBARAKI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGE DNA; RECOMBINASE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME SPECIFICITY; GENE ISOLATION; GENETIC TRANSFORMATION; PRIORITY JOURNAL; PROPHAGE;

EID: 0029975390     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.11.3374-3376.1996     Document Type: Article

References (21)

1. Abremski, K., and S. Gottesman. 1982. Purification of the bacteriophage lambda xis gene product required for λ excisive recombination. J. Biol. Chem. 257:9658-9662.
2. Carrasco, C. D., K. S. Ramaswamy, T. S. Ramasubramanian, and J. W. Golden. 1994. Anabaena xisF gene encodes a developmentally regulated site-specific recombinase. Genes Dev. 8:74-83.
3. Goodfellow, M., S. T. Williams, and M. Mordarski. 1988. Actinomycetes in biotechnology. Academic Press, San Diego, Calif.
4. Hatfull, G. F., and N. D. F. Grindley. 1986. Analysis of γδ resolvase mutants in vitro: evidence for an interaction between serine-10 of resolvase and site I of res. Proc. Natl. Acad. Sci. USA 83:5429-5433.
5. Hatfull, G. F., and N. D. F. Grindley. 1988. Resolvases and DNA-invertases: a family of enzymes active in site-specific recombination, p. 357-396. In R. Kucherlapati and G. R. Smith (ed.), Genetic recombination. American Society for Microbiology, Washington, D.C.
6. Hopwood, D. A., M. J. Bibb, K. F. Chater, T. Kieser, C. J. Bruton, H. M. Kieser, D. J. Lydiate, C. P. Smith, J. M. Ward, and H. Schrempf. 1985. Genetic manipulation of Streptomyces. The John Innes Foundation, Norwich, England.
7. Isogai, T., H. Takahashi, and H. Saito. 1980. High-frequency protoplasttransfection of Streptomyces parvulus 2297 with actinophage R4 DNA. Agric. Biol. Chem. 44:2425-2428.
8. Kikuchi, Y., and H. Nash. 1979. Nicking-closing activity associated with bacteriophage λ int gene product. Proc. Natl. Acad. Sci. USA 76:3760-3764.
9. Kilby, N. J., M. R. Snaith, and J. A. H. Murray. 1993. Site-specific recombinases: tools for genome engineering. Trends Genet. 9:413-421.
10. Kunkel, T. A. 1985. Rapid and efficient site-specific mutagenesis without phonotypic selection. Proc. Natl. Acad. Sci. USA 82:488-492.
11. Matsuura, M., T. Noguchi, T. Aida, M. Asayama, H. Takahashi, and M. Shirai. 1995. A gene essential for the site-specific excision of actinophage R4 genome from the chromosome of a lysogen. J. Gen. Appl. Microbiol. 41:53-61.
12. Mitsui, H., and H. Takahashi. 1992. Cohesive single-stranded ends of Streptomyces temperate bacteriophage R4. Mol. Gen. Genet. 231:360-362.
13. Mitsui, H., and H. Takahashi. 1992. Delimitation of cohesive ends site (cos) of Streptomyces temperate bacteriophage R4. Biochem. Biophys. Res. Commun. 186:1663-1668.
14. Morino, T., T. Isogai, H. Kojima, H. Takahashi, and H. Saito. 1983. Cleavage analysis of actinophage R4 and its deletion mutants. Agric. Biol. Chem. 47:1873-1878.
15. Morino, T., T. Isogai, H. Takahashi, and H. Saito. 1984. Construction of phage vectors in Streptomyces: introduction of the thiostrepton resistant (tsr) gene into R4 phage. Agric. Biol. Chem. 48:1985-1990.
16. Morino, T., K. Takagi, T. Nakamura, T. Takita, H. Saito, and H. Takahashi. 1986. Studies of cosmid transfection in Streptomyces lividans and Streptomyces parvulus. Agric. Biol. Chem. 50:2493-2497.
17. Morino, T., H. Takahashi, and H. Saito. 1985. Construction and characterization of a cosmid of Streptomyces lividans. Mol. Gen. Genet. 198:228-233.
18. Nash, H. A., and C. A. Robertson. 1981. Purification and properties of the Escherichia coli protein factor required for λ integrative recombination. J. Biol. Chem. 256:9246-9253.
19. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Sato, T., Y. Samori, and Y. Kobayashi. 1990. The cisA cistron of Bacillus subtilis sporulation gene spoIVCA encodes a protein homologous to a site-specific recombinase. J. Bacteriol. 172:1092-1098.
21. Shirai, M., H. Nara, A. Sato, T. Aida, and H. Takahashi. 1991. Site-specific integration of the actinophage R4 genome into the chromosome of Streptomyces parvulus upon lysogenization. J. Bacteriol. 173:4237-4239.