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Evidence of embryo- and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion
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Hill JA, Polgar K, Harlow BL, Anderson DJ: Evidence of embryo- and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion. Am J Obstet Gynecol 1992, 166:1044-1052.
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Hill, J.A.1
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Measurement of embryo toxic factors is predictive of pregnancy outcome in women with a history of recurrent abortion
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Yamada H, Polgar K, Hill JA: Cell-mediated immunity to trophoblast antigens in women with recurrent spontaneous abortion. Am J Obstet Gynecol 1994, 170:1339-1344.
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T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion
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Hill JA, Polgar K, Anderson DJ: T-helper 1-type immunity to • trophoblast in women with recurrent spontaneous abortion. JAMA 1995, 273:1933-1936. This study showed a T helper immune response to trophoblast antigens.
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Sane AS, Chokshi SA, Mishra W, Barad DP, Shah VC, Nagpal S: Serum lipoperoxides in induced and spontaneous abortions. Gynecol Obstet Invest 1991, 31:172-175.
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Blood levels of lipids, lipoperoxides, vitamin e and glutathione peroxidase in women with habitual abortion
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Nicotia M, Multinelli C, Sbracia M, Rolf G, Passi S: Blood levels of lipids, lipoperoxides, vitamin E and glutathione peroxidase in women with habitual abortion. Gynecol Obstet Invest 1994, 38:223-226.
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Distribution of placental protein 14 in tissues and body fluids during pregnancy
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Julkunen M, Rutanen E-M, Kostermies A, Ranta T, Bohn H, Seppala M: Distribution of placental protein 14 in tissues and body fluids during pregnancy. Br J Obstet Gynaecol 1985, 2:1145-1151.
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Identification of placental protein 14 as an immunosuppressive factor in human reproduction
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Tulppala M, Julkunen M, Tiitinen A, Stenman U-H, Seppala M: Habitual abortion is accompanied by low serum levels of placental protein 14 in the luteal phase of the fertile cycle. Fertil Steril 1995, 63:792-795.
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Tulppala M, Julkunen M, Tiitinen A, Stenman U-H, Seppala M: Habitual abortion is accompanied by low serum levels of placental protein 14 in the luteal phase of the fertile cycle. Fertil Steril 1995, 63:792-795.
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Suppression by human placental protein 14 of natural killer cell activity and T cell proliferative response
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Okamoto N, Uchida A, Takakura K, Kariya Y, Kamazaki H, Riittinen L, Koistinen R, Seppala M, Tori T: Suppression by human placental protein 14 of natural killer cell activity and T cell proliferative response. Am J Reprod Immunol 1991, 26:137-142.
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14
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Wahlstrom T, Koskimies AI, Tenhunen A, Rutanen E-M, Yki-Jarvinen M, Sjoberg J, Seppala M: Pregnancy proteins in the endometrium after follicle aspiration for in vitro fertilization. Ann NY Acad Sci 1985, 442:402-407.
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Seppala, M.7
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Risk of recurrent abortion after appearance of a chorionic sac or heart rate on avaginal ultrasound
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Dickey RP, Gasses RF, Olar TT, Taylor SN, Curole DN, Rye PH, Matulich EM: Risk of recurrent abortion after appearance of a chorionic sac or heart rate on a]vaginal ultrasound. Lancet 1994, 344:442-443.
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The effectiveness of allogeneic leukocyte immunization in unexplained primary recurrent spontaneous abortion
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Daya S, Gunby J, The Recurrent Miscarriage Immunotherapy Trialists • Group: The effectiveness of allogeneic leukocyte immunization in unexplained primary recurrent spontaneous abortion. Am J Reprod Immunol 1994, 32:294-302. This collaborative meta-analysis of individual patient data showed that the probability of live birth was reduced by 23% for each additional abortion beyond three that the patient had experienced.
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Quenby S, Farquharson RG: Human chorionic gonadotropin • supplementation in recurring pregnancy loss: a controlled trial. Fertil Steril 1994, 62:708-710. In this study hCG treatment resulted in a success rate of 85% compared with 40% using placebo.
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Quenby, S.1
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Controlled trial of treatment of recurrent spontaneous abortion by immunization with paternal cells
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Mowbray JF, Liddel H, Underwood JL, Gibbings C, Reginald PW, Beard RW: Controlled trial of treatment of recurrent spontaneous abortion by immunization with paternal cells. Lancet 1985, 1:941-943.
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Clark DA, Daya S: Trials and tribulations in the treatment of recurrent spontaneous abortion. Am J Reprod Immunol 199125:18-24.
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The Recurrent Mischarriage Immunotherapy Trialists Group: Worldwide • collaborative observational study and meta-analysis on ellogeneic leukocyte immunotherapy for recurrent spontaneous abortion. Am J Reprod Immunol 1994, 32:55-72. This worldwide collaborative observational study organized under the auspices of the Ethics Committee of the American Society of Reproductive Immunology reported a significant improvement in the live birth rate with immunotherapy.
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Mueller-Eckhardt G, Heine O, Neppert J, Kunzel W, Mueller-Eckhardt C: Prevention of recurrent spontaneous abortion by intravenous immunoglobulin. Vox Sang 1989, 51:122-126.
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Mueller-Eckhardt, G.1
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The German RSA/IVIG Group: Intravenous immunoglobulin in the • prevention of recurrent miscarriage. Br J Obstet Gynaecol 1994, 101:1072-1077. A German multicentered, double-blind, randomized, controlled trial conducted with women with unexplained primary recurrent abortion comparing IVIG with 5% human albumin given as placebo. No significant difference in success rates between the IVIG and placebo groups was observed.
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Br J Obstet Gynaecol
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Coulam CB: Alternative treatment to lymphocyte immunization for treatment of recurrent spontaneous abortion. Immunogherapy with intravenous immunoglobulin for treatment of recurrent pregnancy loss: American experience. Am J Reprod Immunol 1994, 32:286-289.
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Coulam, C.B.1
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