Recombinant follicle stimulating hormone (rFSH; Puregon) in assisted reproduction: More oocytes, more pregnancies. Results from five comparative studies

Human Reproduction Update

Volumn 2, Issue 2, 1996, Pages 162-171

  Out, Henk J ^a   Mannaerts, Bernadette M J L ^a   Driessen, Stefan G A J ^a   Coelingh Bennink, Herjan J T ^a  

^a NV ORGANON   (Netherlands)

Author keywords

IVF; Recombinant FSH; Urinary FSH

Indexed keywords

BUSERELIN; GONADORELIN AGONIST; HUMAN MENOPAUSAL GONADOTROPIN; RECOMBINANT FOLLITROPIN; TRIPTORELIN; UROFOLLITROPIN;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFICACY; DRUG PURITY; DRUG SAFETY; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MULTICENTER STUDY; MULTIPLE PREGNANCY; OOCYTE; OVARY HYPERSTIMULATION; PREGNANCY RATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; STEROIDOGENESIS; SUBCUTANEOUS DRUG ADMINISTRATION;

BUSERELIN; CLINICAL TRIALS; EMBRYO TRANSFER; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; HUMANS; LUTEOLYTIC AGENTS; MENOTROPINS; MULTICENTER STUDIES; RECOMBINANT PROTEINS; TRIPTORELIN;

EID: 0029973840     PISSN: 13554786     EISSN: None     Source Type: Journal    
DOI: 10.1093/humupd/2.2.162     Document Type: Review

References (26)

1. Council of Europe (1986) European Pharmacopoeia. 2nd edition, pp. 508-1-4.
2. CPMP Working Party on Efficacy of Medicinal Products (1990) Good clinical practice for trials on medicinal products in the European Community. Pharmacol. Toxicol., 67, 361-372.
3. Daya, S., Gunby, J., Hughes, E.G., Collins, J.A. and Sagle, M.A. (1995) Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis. Fertil. Steril., 64, 347-354.
4. Devroey, P., Van Steirteghem, A., Mannaerts, B. and Coelingh Bennink, H. (1992a) Successful in-vitro fertilisation and embryo transfer after treatment with recombinant human FSH. Lancet, 339, 1170-1171.
5. Devroey, P., Van Steirteghem, A., Mannaerts, B. and Coelingh Bennink, H. (1992b) First singleton term birth after ovarian superovulation with rhFSH. Lancet, 340, 1108-1109.
6. Devroey, P., Mannaerts, B., Smitz, J., Coelingh Bennink, H. and Van Steirteghem, A. (1993) First established pregnancy and birth after ovarian stimulation with recombinant human follicle stimulating hormone (Org 32489). Hum. Reprod., 8, 863-865.
7. Devroey, P., Mannaerts, B., Smitz, J., Coelingh Bennink, H. and Van Steirteghem, A. (1994) Clinical outcome of a pilot efficacy study on recombinant human follicle-stimulating hormone (Org 32489) combined with various gonadotrophin-releasing hormone agonist regimens. Hum. Reprod., 9, 1064-1069.
8. Healy, D.L., Trounson, A.O. and Andersen, A.N. (1994) Female infertility: causes and treatment. Lancet, 343, 1539-1544.
9. Hedon, B., Out, H.J., Hugues, J.N., Camier, B., Cohen, J., Lopes, P., Zorn, J.R., Van der Heijden, B. and Coelingh Bennink, H.J.T. (1995) Efficacy and safety of recombinant FSH (Puregon) in infertile women pituitary-suppressed with triptorelin undergoing in-vitro fertilizations a prospective, randomized, assessor-blind, multicentre trial. Hum. Reprod., 10, 3102-3106.
10. Hughes, E.G., Sagle, M.A., Fedorkow, D.M., van de Koppel, P., Daya, S. and Collins, J.A. (1992) The routine use of gonadotropin-releasing hormone agonists prior to in vitro fertilization and gamete intrafallopian transfer: a meta-analysis of randomized controlled trials. Fertil. Steril., 58, 888-896.
11. Hull, M. (1995) Complications of pregnancy after infertility treatment: awareness and prevention. Br. J. Obstet. Gynaecol., 102, 520-524.
12. Jansen, C.A.M. and Van Os, H.C. (1996) Puregon without analuogues: an oxymoron. Gynecol. Endocrinol., 10 (Suppl. 1), 34.
13. Loumaye, E., Campbell, R. and Salat-Baroux, J. (1995) Human follicle-stimulating hormone produced by recombinant DNA technology: a review for clinicians. Hum. Reprod. Update, 1, 188-199.
14. Out, H.J., Mannaerts, B.M.J.L., Driessen, S.G.A.J. and Coelingh Bennink, H.J.T. (1995a) A prospective, randomized, assessor-blind, multicentre study comparing recombinant and urinary follicle-stimulating hormone (Puregon versus Metrodin) in in-vitro fertilization. Hum. Reprod., 10, 2534-2540.
15. Out, H.J., Reimitz, P.E. and Coelingh Bennink, H.J.T. for the European Puregon Collaborative IVF Study Group (1995b) A prospective, randomized, multicentre study comparing recombinant FSH (Puregon) either given intramuscularly or subcutaneously in subjects undergoing IVF. Hum. Reprod., 10 (Abstract Book 1), 6.
16. Palermo, G., Joris, H., Devroey, P. and Van Steirteghem, A.C. (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet, 340, 17-18.
17. Queenan, J.T., Veeck, L.L. and Muasher, S.J. (1995) Clinical and laboratory aspects of cryopreservation. Semin. Reprod. Endocrinol., 13, 64-71.
18. Recombinant Human FSH Study Group (1995) Clinical assessment of recombinant human follicle-stimulating hormone in stimulating ovarian follicular development before in vitro fertilization. Fertil. Steril., 63, 77-86.
19. Staessen, C., Camus, M., Khan, I., Smitz, J., Van Waesberghe, L., Wisanto, A., Devroey, P. and Van Steirteghem, A.C. (1989) An 18-month survey of infertility treatment by in vitro fertilization, gamete and zygote intrafallopian transfer, and replacement of frozen-thawed embryos. J. In Vitro Fertil. Embryo Transf., 6, 22-29.
20. Steelman, S.L. and Pohley, F.M. (1953) Assay of the follicle-stimulating hormone based on the augmentation with human chorionic gonadotropin. Endocrinology, 53, 604-616.
21. Tarlatzis, B.C., Grimbizis, G., Pournaropoulos, F., Bontis, J., Lagos, S., Pados, G. and Mantelenakis, S. (1994) Evaluation of two gonadotropin-releasing hormone (GnRH) analogues (leuprolide and buserelin) in short and long protocols for assisted reproduction techniques. J. Assist. Reprod. Genet., 11, 85-91.
22. Toner, J.P., Brzyski, R.G., Oehninger, S., Veeck, L.L., Simonetti, S. and Muasher, S.J. (1991) Combined impact of the number of pre-ovulatory oocytes and cryopreservation on IVF outcome. Hum. Reprod., 6, 284-289.
23. Vandekerckhove, P., O'Donovan, P.A., Lilford, R.J. and Harada, T.W. (1993) Infertility treatment: from cookery to science. The epidemiology of randomised controlled trials. Br. J. Obstet. Gynaecol., 100, 1005-1036.
24. Wang, X.J., Ledger, W., Payne, D., Jeffrey, R. and Matthews, C.D. (1994) The contribution of embryo cryopreservation to in-vitro fertilization/gamete intra-Fallopian transfer: 8 years experience. Hum. Reprod., 9, 103-109.
25. Whitehead, A. and Whitehead, J. (1991) A general parametric approach to the meta-analysis of randomised clinical trials. Statist. Med., 10, 1665-1677.
26. Zador, I.E., Sokol, R.J. and Chik, L. (1988) Interobserver variability. A source of error in obstetric ultrasound. J. Ultrasound Med., 7, 245-249.