Effect of lnterleukin-10 on Anti-CD40- and lnterleukin-4-lnduced Immunoglobulin E Production by Human Lymphocytes

International Archives of Allergy and Immunology

Volumn 110, Issue 3, 1996, Pages 225-232

  Uejima, Yasuhide ^a   Takahashi, Katsushi ^a   Komoriya, Keiji ^a   Kurozumi, Seizi ^a   Ochs, Hans D ^b  

^a TEIJIN LTD   (Japan)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

CD40; IgE; IgG; IL 10; IL 4

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE; MONONUCLEAR CELL; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ANTIGENS, CD40; B-LYMPHOCYTES; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MALE; TONSIL;

EID: 0029973811     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237291     Document Type: Article

References (44)

1. Vcrcclli D, Geha RS: Regulation oflgE synthesis in humans, J Clin Immunol 1989;9:75-83.
2. Noelle RJ, Roy M, Shepherd DM, Stamenkovie I, Ledbetter JA, Aruffo A: A 39-kDa protein on activated helper T cells bind CD40 and trasduc-es the signal for cognate activation of B cells, Proc Natl Acad Sci USA 1992;89:6550-6554.
3. Hollcnbaugh I, Ochs I ID, Noelle R.I, Ledbetter JA, Aruffo A: The role of CD40 and its ligand in the regulation of the immune response, Immunol Rev 1994;138:23-37.
4. Zhang K, Clark EA, Saxon A: CD40 stimulation provides an IFN-y-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production, J Immunol 1991;146:1836-1842.
5. Gascan H, Gauchat J F, Aversa G, van Vlasselacr P, de Vries JE: Anti-CD40 monoclonal antibodies or (1)4 - T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways, J Immunol 1991; 147:8-13.
6. Splawski JB, Fu SM, Iipskv PE: Immunoregu-latory role of CD40 in human B cell differentiation, J Immunol 1993:150:1276-1285.
7. Pcne J, Roussel F, Briere F, Chretien I, Weide-man J, Bonnefoy JY, de Vries JE: Interleukin 5 enhances interleukin 4-induced IgE production by normal human B cells, The role of soluble CD23 antigen, Eur J Immunol 1988; 18:929— 935.
8. Jabara HH, Fu SM, Geha RS, Vcrcelli D: CD40 and IgF.: Synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells, J Exp Med 1990:172:1861 -1864.
9. Kimita H, Yoshid A, Ishioka C, Lindlcy I, Mika-wa H: Interleukin 8 (IL-8) selectively inhibits immunoglobulin E production induced by IL-4 in human B cells, J Exp Med 1992:176:1227- 1231.
10. Kiniwa M, Gately M, Gubler U, Chizzonilc R, Fargeas C, Dclcspesse G: Recombinant interleukin- 12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytes, J Clin Invest 1992;90:262-266.
11. Fiorentino DF, Bond MW, Mosmann TR: Two types of mouse T helper cell, IV Th2 clones secrete a factor that inhibits cytokine production by fill clones, J Exp Med 1989:170:2081- 2095.
12. O’Garra A, Stapleton G, Char V, Pearce M, Schumacher J, Rugo LL, Barbis D, Stall A, Cupp J, Moore KW, Vieira P, Mosmann T, Whitmore A, Arnold L, LLaughton G, Howard VI: Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10, Int Immunol 1990:2:821-832.
13. Fiorentino DF, Zlotnik A, Vieira P, Mosmann TR, Howard M, Moore KW, O’Garra G: IL-10 acts on the antigen-presenting eell to inhibit cytokine production by Till cells, J Immunol 1991;146:3444-3451.
14. Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, O'Garra A: IL-10 inhibits cytokine production by activated macrophages, J Immunol 1991:147:3815-3822.
15. de Waal Malefyt R, Abrams JS, Bennett B, Fig-dor CG, de Vries JE: Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes, J Exp Med 1991:174:1209-1220.
16. Benjamin D, Knobloch TJ, Dayton MA: Human B-cell interleukin-10: B-eell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitu-tively secrete large quantities of interleukin-10, Blood 1992:80:1289- 1298.
17. Yssel II, dc Waal Malefyt R, Roncarolo MG, Abrams JS, Lahesmaa R, Spits II, de Vries IE: IL-10 is produced by subsets of human 0)4 T cell clones and peripheral blood T cells, J Immunol 1992:149:2378-2384.
18. MacNeil I A, Suda T, Moore KW, Mosmann TR, Zlotnik A:IL-10, a novel growth cofactor for mature and immature T cells. I Immunol 1990: 145:4167-4173.
19. Go NF, Castle BE, Barrett R, Kastelcin R, Dang W, Mosmann TR, Moore KW, Howard M: Interleukin 10, a novel B cell stimulatory factor: Unresponsiveness of X chromosome-linked immunodeficiency B cells, J Exp Med 1990: 172:1625-1631.
20. Thompson-Snipes L, Dliar V, Bond MW, Mos-mann TR, Moore KW, Rennick DM: Interleukin 10: A novel stimulatory factor for mast cells and their progenitors, J Exp Med 1991:173: 507-510.
21. de Waal Malefyt R, Haancn J, Spits H, Roncarolo MG, te Velde A, Figdor C, Johnson K, Kaste-lein R, Yssel H, de Vries JE: Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression, J Exp Med 1991:174:915-924.
22. Bogcan C, Vodovotz Y, Nathan C: Macrophage deactivation by interleukin 10, J Exp Med 1991; 174:1549-1555.
23. Rousette F, Garcia E, Dcfrance T, Peronne C, Vezzio N, Hsu DLL, Kastelcin R, Moore KW, Banchcreau J: Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes, Proc Natl Acad Sci USA 1992; 89:1890-1893.
24. Nonoyama S, Hollcnbaugh D, Aruffo A, Ledbetter JA, Ochs I ID: B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells, J Exp Med 1993:178:1097-1102.
25. Defrance T, Vanbervlict B, Briere F, Durand I, Roussel F, Banchcreau J: Interleukin 10 and transforming growth factor 1 cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A, J Exp Med 1992; 175:671-682.
26. Punnonen J, de Waal Malefyt R, van Vlasselaer P, Gauchat JF, de Vries JE: IL-lOand viral IL-10 prevent lL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes, J Immunol 1993; 151:1280-1289.
27. Yanagihara Y, Kajiwara K, Ikizaka K, Koshiro T, Okumura N, Ra C: Recombinant soluble form of the human high affinity immunoglobulin E (IgE) receptor inhibits IgE production through its specific binding to IgE-bearing B cells, J Clin Invest 1994;94:2162-2165.
28. Nonoyama S, Farrington M, Ishida H, Howard M, Ochs HD: Activated B cells from patients w ith common variable immunodficiency prolif-eratcand synthesize immunoglobulin, J Clin Invest 1993:92:1282-1287.
29. Nonoyama S, Penix LA, Edwards CP, Lewis DB, Ito S, Aruffo A, Wilson CB, Ochs I ID: Diminished expression of CD40 ligand by activated T cells, J Clin Invest 1995:95:66-75.
30. Ranheim EA, Kipps TJ: Activated T cells induce expression of B7/BBI on normal or leukemic B cell through a CD40-dcpendcnt signal, J Exp Med 1993:177:925- 935.
31. Chatta GS, Spies AG, Chang S, Mize GJ, Lin-slcy PS, Ledbetter JA, Morris DR, Differential regulation of proto-oncogenes c-jnnand c-Josin T lymphocytes activated through CD28, J Immunol 1994;153:5393-5401.
32. Fraser JD, Weiss A: Regulation of T-ccll lym-phokinc gene transcription by the accessory molecule CD28, Mol Cell Biol 1992:12:4357- 4363.
33. II irano T, Yasukawa K, Harada LL, Taga T, Wata-nabe Y, Matsuda T, Kaslmvamura S, Nakajima K, Koyama K, Iwamatsu A, Tsunasawa S, Sasa-kiyma F, Matsui U, Tarahara Y, Taniguchi T, Kishimoto T: Complementary DNA fora novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin, Nature 1986;324:73-76.
34. Akira S, 11 irano T, Taga T, Kishimoto T: Biology of multifunctional cytokines; IL-6 and related moleculres (IL-I and TNF), FASEB J 1990:4:2860-2867.
35. Clark EA, Shu G: Association between IL-6 and CD40 signaling: IL-6 induces phosphorylation of CD40 receptors, J Immunol 1990:145: 1400-1406.
36. van Kooten C, Rensink I, Pascal-Salceda D, van Oers R, Aardcn L: Monokine production by human T cells: 1L-1« production restricted to memory T cells, J Immunol 1991:146:2654—2658.
37. Vercelli D, Jabara HH, Arai K, Yokota T, Geha RS: Endogenous interleukin 6 plays an obligatory role in interleukin 4-dcpendent human IgE synthesis, EurJ Immunol 1989;19:1419-1424.
38. Maggi E, del Prcte GF, Parronchi P, Tiri A, Mac-cltia D, Biswas P, Simonclli C, Ricci M, Romag-nani S: Role for T cells, IL-2 and IL-6 in the IL-4-depcndcnt in vitro human IgE synthesis, Immunology 1989:68:300-306.
39. Taga T, Kawanishi Y, Hardy RR, Hirano T, Kishimoto Y: Receptors for B cell stimulatory factor 2, Quantitation, specificity, distribution, and regulation of their expression, J Exp Med 1987:166:967-981.
40. Pcne J, Roussct F, Brierc F, Chretin I, Bonnefoy JY, Spits H, Yokota T, Arai N, Arai K, Banclic-reau J, de Vries JE: IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferon'/ and it and prostaglandin F., Proc Natl Acad Sci USA 1988:85: 6880-6884.
41. Shapira SK, Vercelli D, Jabara HH, Fu SM, Gc-ha RS: Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen, J Exp Med 1992; 175:289-292.
42. Nonoyama S, Farrington ML, Ochs HD: Effect of IL-2 on immunoglobulin production by anti-CD40-activated human B cells, Synergistic effect with IL-IO and antagonistic effect with IL-4, Clin Immunol Immunopathol 1994;72: 373-379.
43. Burdin N, Van Kooten C, Galibert I., Abrams JS, Wijdenes J, Banchcreau J, Roussct F: Endogenous IL-6 and II.-I0 contribute to the differentiation of CD40-activated human B lymphocytes, J Immunol 1995; 154:2533-2544.
44. Bober LA, Grace MJ, Pugliese-Sivo C, Waters TA, Sullivan LM, Narula SK: Human IL-10 reduces the number of IL-4-induccd IgE B cells in cultures of atopic mononuclear cells, hit Arch Allergy Immunol 1994;105:26-31.