Differential involvement of Th1 and Th2 cytokines in autoimmune diseases

Autoimmunity

Volumn 24, Issue 1, 1996, Pages 25-33

  Kroemer, Guido ^a   Hirsch, François ^a   González García, Ana ^a   Martínez A, Carlos ^b  

^a CNRS   (France)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROMAZINE; CYTOKINE;

ALLERGIC ENCEPHALOMYELITIS; ARTICLE; AUTOIMMUNITY; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; ETIOLOGY; HELPER CELL; INSULIN DEPENDENT DIABETES MELLITUS; SUPPRESSOR CELL;

EID: 0029973211     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939608995354     Document Type: Article

References (68)

1. Kroemer, G., Martinez-A. C. Cytokines and autoimmune disease. Clin. Immunol. Immunopathol. 1991; 61: 275-295.
2. Holán, V., Lamb, J. R., Malkovsky, M. Immunological tolerance and lymphokines. Crit. Rev. Immunol. 1991; 482: 481-493.
3. Kroemer, G., Martínez-A. C. (Eds.). Cytokines and Autoimmunity. Sem. Immunol. 1992; 4(3): 129-202.
4. Kroemer, G. M., de Alboran, I., Gonzalo, J. A., Martínez-A. C. Immunoregulation by cytokines. Crit. Rev. Immunol. 1993; 13: 163-191.
5. Mosmann, T. R., Coffman, R. L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. 1989; 7: 145-173.
6. Romagnani, S. Human TH1 and TH2 subsets: doubt no more. Immunol. Today 1991; 12: 256-257.
7. Paul, W. E, Seder, R. A. Lymphocyte responses and cytokines. Cell 1994; 76: 241-251.
8. Fitch, F. W., McKisic, M. D., Lancki, D. W., Gajewski, T. F. Differential regulation of murine T lymphocyte subsets. Ann. Rev. Immunol. 1993; 11: 29-48.
9. Powrie, F., Coffman, R. L. Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol. Today 1993; 14: 270-274.
10. Romagnani S. Lymphokine production by human T cells in disease states. Ann. Rev. Immunol. 1994; 12: 227-258.
11. Clerici, M., Shearer, G. M. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol. Today 1994; 15: 575-581.
12. Caspi, R. R., Roberge, F. G., McAllister, C. G., El-Saied, M., Kuwabara, T., Gery, I. et al. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J. Immunol. 1986; 136: 928-933.
13. Roberge, F. G., Lorberboum-Galski, H., Hoang, P. L, de Smet, M., Chan, C. C., Fitzgerald, D. et al. Selective immunosuppression of activated T cells with the chimeric toxin IL-2-PE40: Inhibition of experimental autoimmune uveoretinitis. J. Immunol. 1989; 143: 3498-3502.
14. Goldman, M., Druet, P., Gleichmann, E. TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity. Immunol Today 1991; 12: 223-227.
15. Saoudi, A., Kuhn, J., Huygen, K., de Kozak, Y., Velu, T., Goldman, M. et al. TH2 activate cells prevent experimental autoimmune uveoretinitis, a TH1-dependent autoimmune disease. Eur. J. Immunol. 1993; 23: 3096-3103.
16. Kühn, R., Lôhler, J., Rennick, D., Rajewsky, K., Müller, W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993; 75: 263-274.
17. Sadlack, B., Merz, H., Schorle, H., Schimpl, A., Feller, A. C., Horak, I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Eur. J. Immunol. 1993; 75: 253-261.
18. Strober, W., Ehrhardt, R. O. Chronic intestinal inflammation: an unexpected outcome in cytokine or T cell receptor mutant mice. Cell 1993; 75: 203-205.
19. low subset. J. Exp. Med. 1990; 172: 1701-1708.
20. + T cells. J Exp. Med. 1993; 178: 237-244.
21. + T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int. Immunol. 1993; 5: 1461-1471.
22. + T cells. J. Immunol. 1990; 144: 3288-3295.
23. + T cells. Eur. J. Immunol. 1991; 21: 1187-1194.
24. Mustafa, M., Vingsbo, C., Olsson, T., Ljungdahl, A., Höjeberg, B., Holmdahl, R. The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis. Eur. J. Immunol. 1993; 23: 3089-3095.
25. Powell, M. B., Mitchell, D., Lederman, J., Buckmeier, J., Zamvil, S. S., Graham, M. et al. Lymphotoxin and tumor necrosis factor-alpha production by myelin basis protein-specific T cell clones correlates with encephalitogenicity. Int. Immunol. 1990; 2: 539-544.
26. Panitch, H. S., Hirsch, R. L., Schindler, J., Johnson, K. P. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurol. 1987; 37: 1097.
27. Vecht, C. J., Keohane, C., Menon, R. S., Henzenlogmans, S. C, Punt, C. J. A., Stoter, G. Acute fatal leukoencephalopathy after interleukin treatment. N. Engl. J. Med. 1990; 323: 1146-1147.
28. + suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Immunol. 1992; 22: 1757-1763.
29. Racke, M. K., Bonomo, A., Scott, D. E., Cannella, B., Levine, A., Raine, C. S. et al. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J. Exp. Med. 1994; 180: 1961-1966.
30. Khoury, S. J., Hancock, W. W., Weiner, H. L. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encepahlomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 1992; 176: 1355-1364.
31. Kennedy, M. K., Torrance, D. S., Picha, K. S., Mohler, K. M. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals IL-10 mRNA expression correlates with recovery. J. Immunol 1992; 149: 2496-2505.
32. Sarvetnick, N., Shizuru, J., Liggitt, D., Martin, L, Mclntyre, B., Gregory, A. et al. Loss of pancreatic islet tolerance induced by β cell expression of interferon-g. Nature 1990; 346: 844-847.
33. Allison, J., Heath, W., Miller, J. F. A. P. Does interleukin-2 abrogate peripheral immunological selftolerance in vivo? Sem. Immunol. 1992; 4: 181-186.
34. Higuchi, Y., Hetrera, P., Huarte, J., Belin, D., Ohashi, P., Aichele, P. et al. Expression of a tumor necrosis factor alpha transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes. J. Exp. Med. 1992; 176: 1719-1731.
35. Wogensen, L, Huang, X., Sarvetnick, N. Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Lamgerhans. J. Exp. Med. 1993; 178: 175-185.
36. Allison, J., Oxbrow, L., Miller, J. F. A. P. Consequences of in situ production of IL-2 for islet cell death. Int. Immunol. 1994; 6: 541-549.
37. Rapoport, M. J., Jaramillo, A., Zipris, D., Lazarus, A. H., Serreze, D. V., Leiter, E. H. et al. Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J. Exp. Med. 1993; 178: 87-99.
38. + T cells and their roles in the induction and prevention of autoimmunity. Immunol. Rev. 1991; 123: 37-64.
39. + T cell subset that inhibits this autoimmune potential. J. Exp. Med. 1993; 177: 627-636.
40. Bendelac, A., Matzinger, P., Seder, R. A., Paul, W. E., Schwartz, R. H. Activation events during thymic selection. J. Exp. Med. 1992; 175: 731-742.
41. Campbell, I. L., Oxbrow, L., Harrison, L. C. Reduction in insulitis following administration of IFN-g and TNF-a in the NOD mouse. J. Autoimm. 1991; 4: 249-262.
42. Alfons, B., Heremans, H., Vandekerckhove, F., Dijkmans, R., Sobis, H., Meulepas, E. et al. Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-g. J. Immunol. 1988; 140: 1506-1510.
43. Pankewycz, O., Strom, T. B., Rubin-Kelley, Y. E. Isletinfiltrating T cell clones from non-obese diabetic mice that promote or prevent accelerated onset diabetes. Eur. J. Immunol. 1991; 21: 873-879.
44. + T cell clone, I.S.2.15, has in vitro immunosuppressive properties. Eur. J. Immunol. 1992; 22: 1017-1022.
45. Wicker, L. S., Todd, J-A., Prins, J. B., Podolin, P. L., Renjilian, R. I., Peterson, L. B. Resistance alleles at two non-major histocompatibility complex-linked insulindependent diabetes loco on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes. J. Exp. Med. 1994; 180: 1705-1713.
46. de Wit, D., van Mechelen, M., Zanin, C., Doutrelepont, J-M., Velu, T., Gérard, C. et al. Preferential activation of Th2 cells in chronic graft-versus-host reaction. J. Immunol. 1993; 150: 361-366.
47. Gutierrez-Ramos, J. C., Andreu, J. L., Revilla, Y., Viñuela, E., Martinez-A. C. Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus. Nature 1990; 346: 271-274.
48. Kroemer, G., Andreu-Sánchez, J. L., Gonzalo, J. A., Gutierrez-Ramos, J. C., Martínez-A. C. Interleukin-2, autotolerance, and autoimmunity. Adv. Immunol. 1991; 150: 147-235.
49. + B) cells. Int. J. Clin. Lab. Res. 1992; 22: 220-234.
50. Ishida, H., Muchamuel, T., Sakaguchi, S., Andrade, S., Menon, S., Howard, M. Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J. Exp. Med. 1994; 179: 305-310.
51. Gilliland, B. C. Drug-induced autoimmune and hematologic disorders. Drug Allergy 1991; 11: 525-553.
52. Llorente, L, Richaudpatin, Y., Wijdenes, J., AlcocerVarela, J., Maillo, M. C., Durand-Gasselin, I. et al. Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus. European Cytokine Network 1993; 4: 421-427.
53. Gibbons, R. B. Complication of chimiotherapy. A review of recent studies. Arch. Intern. Med. 1979; 46: 3343-3345.
54. Nakayama, H., Niki, F., Shono, M., Hada, S. Mercury exanthem. Contact Dermatitis 1983; 9: 411-417.
55. Fillastre, J. P., Druet, P., Méry, J. P. Proteinuric nephropaties associated with drugs and substances of abuse. In: Cameron, J. S., Glassock, R. J., eds. The nephrotic syndrome. Basel, New York: Dekker M 188; 697-744.
56. 2-induced autoimmunity. Clin. Exp. Immunol. 1991; 86: 118-123.
57. Prigent, P., Saoudi, A., Druet, P., Hirsch, F. Mercuric chloride, a chemical responsible for Th2-mediated autoimmunity in Brown-Norway rats, directly triggers T cells to produce IL-4. J. Clin. Invest. 1995.
58. McKnight, A. J., Classon, B. J. Biochemical and immunological properties of rat recombinant interleukin-2 and interleukin-4. Immunology 1992; 75: 286-292.
59. Delespesse, G., Suter, U., Mossalayi, D., Bettler, B., Sarfati, M., Hofstetter, H. et al. Expression, structure, and function of the CD23 antigen. Adv. Imunol. 1990; 49: 149-191.
60. Burlingame, R. W., Rubin, R. L. Drug-induced antihistone autoantibodies display two patterns of reactivity with substructures of chromatin. J. Clin. Invest. 1981; 88: 680-690.
61. Hess, E. V. Drug-related lupus. Curr. Opinion Rheumatol. 1991; 3: 809-814.
62. Quismorio, F. P., Bjarnason, D. F., Kiely, W. F. Antinuclear antibodies in chronic psychotic patients treated with chlorpromazine. Am. J. Psychiatr. 1975; 132: 1204-1209.
63. Canoso, R. T., deOliveira, R. M. Chlorpromazineinduced anticardiolipin antibodies and lupus anticoagulant: absence of thrombosis. Am. J. Hematol. 1988; 27: 272-277.
64. Zucker, S., Zarrabi, H. M., Schubach, W. H., Varma, A., Derman, R., Lysik, R., M. et al. Chlorpromazineinduced immunopathy: progressive increase in serum IgM. Medicine (Baltimore) 1990; 69: 92-100.
65. Roudebush, R. E., Berry, P. L., Layman, N. K., Butler, L. D., Bryant, H. U. Dissociation of immunosuppression by chlorpromazine and trifluoperazine from pharmacological activities as dopamine antagonists. Int. J. Immunopharmacol. 1991; 13: 961-968.
66. Tarazona, R., González-García, A., Zamzami, N., Frechin, N., Gonzalo, J. A., Ruiz-Gayo, M. et al. Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo. J. Immunol. 1995; in press.
67. Moore, K. W., O'Garra, A., Malefyt, R. W., Vieira, P., Mosmann, T. R. Interleukin 10. Ann. Rev. Immunol. 1993; 11: 165-190.
68. Kroemer, G., de Cid, R., Moreno de Alboran, N., Gonzalo, J-A., Iglesias, A., Martinez-A. C el al. Immunological self tolerance: an analysis employing cytokines or cytokine receptors encoded by transgenes or by a recombinant vaccinia virus. Immunol. Rev. 1991; 122: 183-204.