Initiation and regulation of CD4+ T-cell function in host-parasite models

Chemical Immunology

Volumn 63, Issue , 1996, Pages 51-65

  Jankovic, Dragana ^a   Sher, Alan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

CELL; HELPER CELL; HOST PARASITE INTERACTION; HUMAN; IMMUNE RESPONSE; IMMUNITY; PARASITOSIS; PRIORITY JOURNAL; REVIEW; SCHISTOSOMA MANSONI; T LYMPHOCYTE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; HOST-PARASITE RELATIONS; PARASITIC DISEASES;

EID: 0029972680     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (67)

1. Scott P, Sher A. Immunoparasitology: in Paul WE (ed): Fundamental Immunology, New York, Raven Press, 1993, pp 1179-1210.
2. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL: Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins J Immunol 1986;136:2348-2357
3. Scott P, Kaufmann SHE: The role of T-cell subsets and cytokines in the regulation of infection. Immunol Today 1991;12:346-348.
4. Finkelman F, Pearce EJ, Urban JP, Sher A: Regulation and biological function of helminth-induced cytokine responses. Immunol Today 1991;12:A62-A66.
5. Croft M, Carter L, Swain SL, Dutton RW: Generation of polarized antigen-specific CD8 effector populations: Reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med 1994;180:1715-1728.
6. H2 cytokines and help B cells. Science 1993;260:1802-1805.
7. Ferrick DA, Schrenzel MD, Mulvania T, Hsieh B, Ferlin WG, Lepper H: Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 1995;373:255-257.
8. Denkers EY, Gazzinelli RT, Martin D, Sher A: Emergence of NK1.1+ cells as effectors of IFN-γ dependent immunity to Toxoplasma gondu in MHC class I-deficient mice J Exp Med 1993;178: 1465-1472.
9. pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 1994;179:1285-1295
10. Conrad DH, Ben-Sasson SZ, Le Gros G, Finkelman FD, Paul WE, Infection with Nippostrongylus brasiliensis or injection of anti-IgD antibodies markedly enchances Fc-receptor-mediated interleukin 4 production by non-B, non-T cells. J Exp Med 1990;171:1497-1508.
11. Williams ME, Kullberg MC, Barbieri S, Caspar P, Berzofsky JA, Seder RA, Sher A: Fcε receptor-positive cells are a major source of antigen-induced interleukin-4 in spleens of mice infected with Schistosoma mansoni Eur J Immunol 1993;23:1910-1916.
12. Villanueva POF, Reiser H, Stadecker MJ: Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. J Immunol 1994;153:5190-5199.
13. Velupillai P, Harn DA: Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: A mechanism for regulation of CD4+ T-cell subsets. Proc Natl Acad Sci USA 1994;91:18-22.
14. Gazzinelli RT, Hakim FT, Hieny S, Shearer GM, Sher A: Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxoplasma gondii vaccine, J Immunol 1991;146:286-292.
15. Hakim FT, Gazzinelli RT, Denkers EY, Hieny S, Shearer GM, Sher A: CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells. J Immunol 1991;147:2310-2316.
16. Grzych J-M, Pearce E, Cheever A, Caulada ZA, Caspar P, Hieny S, Lewis F, Sher A: Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni. J Immunol 1991;146:1322-1327.
17. Cohn RG, Williams ME, Sher A, Caulfield JP: Schistosoma mansoni: Characterization of an FcεR+ population of granule-containing splenocytes isolated from infected mice. Exp Parasitol 1995,80 339-341.
18. Paul WE, Seder RA, Plaut M: Lymphokine and cytokine production by FcεRI+ cells Adv Immunol 1993;53:1-29.
19. Burd PR, Thompson WC, Max EE, Mills FC Activated mast cells produce interleukin 13. J Exp Med 1995;181:1373-1380
20. H2 cells. Eur J Immunol 1990;20:2067-2074
21. Street NE, Schumacher JH, Fong AT, Bass H, Forentino DF, Leverah JA, Mosmann TR: Heterogeneity of mouse helper T cells: Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J Immunol 1990;144:1629-1639.
22. low CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med 1994;179.589-600.
23. Sher A, Fiorentino DF, Caspar P, Pearce E, Mosmann T: Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J Immunol 1991;147:2713-2716.
24. Powrie F, Menon S, Coffman RL: Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo Eur J Immunol 1993;23:2223-2229.
25. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 1989;170:2081-2095.
26. Murphy EE, Terres G, Macatonia SE, Hsieh C-S, Mattson J, Lanier L, Wysocka M, Trinchieri G, Murphy KM, O'Garra A: B7 and interleukin 12 cooperate for proliferation and interferon γ production by mouse T helper clones that are unresponsive to B7 costimulation. J Exp Med 1994; 180:223-231.
27. Hsieh C-S, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM. Development of Th1 CD4+ cells through IL-12 produced by Listeria-induced macrophages. Science 1993;260: 547-549.
28. Villanueva POF, Chikunguwo SM, Harris TS, Stadecker MJ: Role of IL-10 on antigen-presenting cell function for schistosomal egg-specific monoclonal T helper cell responses in vitro and in vivo J Immunol 1993;151:3192-3198.
29. Gajewski TF, Fitch FW: Antil-prohferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 1988;140: 4245-4252.
30. Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W: Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993;75:263-274.
31. Mocci S, Coffman RL: Induction of a Th2 population from polarized Leishmania-specific Th1 population by in vitro culture with IL-4. J Immunol 1995;154:3779-3787.
32. h2 populations. Int Immunol 1995;7:in press.
33. Nabors GS, Farrell JP: Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses Infect Immun 1994,62:5498-5504.
34. Nabors GS, Afonso LCC, Farrell JP, Scott P: Switch from a type 2 to type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and pentostan. Proc Natl Acad Sci USA 1995;92:3142-3146
35. Slier A, Oswald IP, Hieny S, Gazzinelli RT: Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α. J Immunol 1993,150:3982-3989.
36. Gazzinelli RT, Hieny S, Wynn TA, Wolf S, Sher A: Interleukin 12 is required for the T-lymphocyte-independent induction of Interferon γ by an intracellular parasite and induces resistance in T-cell-deficient host. Proc Natl Acad Sci USA 1993,90:6115-6119.
37. Hunter CA, Remington JS: Regulation of IL-12 and TNF-α induced NK cell production of IFN-γ by IL-1β and TGF-β (abstr A198). Eur Cytokine Netw 1994;5-145.
38. Flesch IEA, Hess JH, Huang S, Aguet M, Rothe J, Bluethmann H, Kaufmann SHE: Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α. J Exp Med 1995,181:1615-1621.
39. Gazzinelli RT, Wysocka M, Hayashi S, Denkers EY, Hieny S, Caspar P, Trinchieri G, Sher A: Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol 1994;153:2533-2543.
40. Hsieh C-S, Macatonia SE, O'Garra A, Murphy KM: T cell genetic background determines default T helper phenotype development in vitro. J Exp Med 1995;181:713-721.
41. Denkers EY, Caspar P, Sher A: Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes. J Exp Med 1994;180: 985-994.
42. Swain SL, Weinberg AD, English M, Huston G: IL-4 directs the development of Th2-like helper effectors. J Immunol 1990;145:3796-3806.
43. Abehsira-Amar O, Gibert M, Joliy M, Thèze J, Jankovic DLj: IL-4 plays a dominant role in the differential development of ThO into Th1 and Th2 cells. J Immunol 1992;148:3820-3829.
44. Abehsira-Amar O, Thèze J, Jankovic DLj: Characterization of two types of T helper precursor cells: Effects of lymphokines on their differentiation into Th1 or Th2 subsets. Bull Inst Pasteur 1992;90.231-243.
45. Kamogawa Y, Minasi L-A, Carding SR, Bottomly K, Flavell RA: The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4 producing cells. Cell 1993;75. 985-995.
46. Vella AT, Pearce EJ: CD4+ Th2 response induced by Scistosoma mansoni eggs develops rapidly through an early transient Th0-like stage. J Immunol 1982,148:2283-2290.
47. Wynn TA, Eltoum I, Cheever AW, Lewis FA, Gause WC, Sher A: Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni J Immunol 1993;151:1430-1440.
48. Oswald IP, Caspar P, Jankovic D, Wynn TA, Pearce EJ, Sher A: IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni. J Immunol 1994;153:1707-1713.
49. Wynn TA, Eltoum I, Oswald IP, Cheever AW, Sher A: Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med 1994;179 1551-1561.
50. Tanaka T, Hu-Li J, Seder RA, de St, Groth BF, Paul WE Interleukin 4 suppresses interleukin 2 and interferon γ production by naive T cells stimulated by accessory cell-dependent receptor engagement. Proc Natl Acad Sci USA 1993,90 5914-5918.
51. Vella AT, Pearce EJ: CD4+ T-cell receptor Vβ usage during the immune response to Schistosoma mansoni. Infect Immun 1993;61:5381-5383.
52. Röcken M, Müller KM, Saurat J-H, Müller I, Louis JA. Cerottini J-C, Hauser C: Central role for TCR/CD3 ligation in the differentiation of CD4+ T cells toward a Th1 or Th2 functional phenotype. J Immunol 1992;148:47-54.
53. Schmitz J, Thiel A, Kühn R, Rajewsky K, Müller W, Assenmacher M, Radbruch A: Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells. J Exp Med 1994;179:1349-1353.
54. Wynn TA, Jankovic D, Hieny S, Zioncheck K, Jardieu P, Cheever AW, Sher A: IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-γ. J Immunol 1995;154:3999-4009.
55. Bancroft AJ, Else KJ, Grencis RK: Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response. Eur J Immunol 1994;24:3113-3118.
56. Bretscher PA, Wei G, Menon JN, Bielefeldt-Ohmann H: Establishment of stable, cell-mediated immunity that makes 'susceptible' mice resistant to Letshmania major. Science 1992;257:539-542.
57. Caulada-Beriedetti Z, Al-Zamel F, Sher A, James S: Comparison of Th1- and Th2-associated immune reactivities stimulated by single versus multiple vaccination of mice with irradiated Schistosoma mansoni cercariae. J Immunol 1991;146:1655-1660.
58. Murray JS, Pffeifer C, Madri J, Bottomly K: Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell-mediated responses in mice of distinct MHC genotype. Eur J Immunol 1992;22:559-565.
59. Pffeifer C, Stein J, Southwood S, Ketelaar H, Sette A, Bottomly K: Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 1995,181.1569-1574.
60. Epstein MM, Di Rosa F, Jankovic D, Sher A, Matzinger P: Successful T cell priming in B cell deficient mice. J Exp Med 1995;182:915-922.
61. Kubin M, Kamoun M, Trinchieri G: Interleukin-12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokme production of human T cells. J Exp Med 1994;180:211-222.
62. Lu P, Zhou X, Chen S-J, Moorman M, Morris SC, Finkelman FD, Linsley P, Urban JF, Gause WC: CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite. J Exp Med 1994;180:693-698
63. Corry DB, Reiner SL, Linsley PS, Locksley RM: Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J Immunol 1994,153: 4142-4148.
64. Heinzel FP, Schoenhaut DS, Rerko RM, Rosser LE, Gately MK Recombinant interleukin 12 cures mice infected with Leishmania major. J Exp Med 1993;177:1505-1509.
65. Afonso LCC, Scharton TM, Vieira LQ, Wysocka M, Trinchieri G, Scott P: The adjuvant effect of interleukin-12 in a vaccine against Leishmania major. Science 1994;263:235-237.
66. Wynn TA, Cheever AW, Jankovic D, Poindexter RW, Caspar P, Lewis FA, Sher A: An IL-12 based vaccination method for preventing fibrosis induced by schistosome infection Nature 1995;376: 594-596.
67. Urban JF, Maliszewski CR, Madden KB, Katona IM, Finkelman FD: IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice. J Immunol 1995;154:4675-4684.