Genetic complementation of radiation response by 3′ untranslated regions (UTR) of RNA

International Journal of Radiation Biology

Volumn 69, Issue 3, 1996, Pages 385-395

  Chen, P ^a   Girjes, A A ^a   Hobson, K ^a   Beamish, H ^a   Khanna, K K ^a   Farrell, A ^a   Gatei, M ^a   Teale, B ^a   Buchwald, M ^b   Legerski, R ^c,d   Lavin, M F ^a,e  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TEXAS   (United States)

^e UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA; ATAXIA TELANGIECTASIA;

COMPLEMENTARY DNA; TRANSCRIPTION FACTOR;

ARTICLE; ATAXIA TELANGIECTASIA; CELL CULTURE; PRIORITY JOURNAL; RADIOSENSITIVITY;

ATAXIA TELANGIECTASIA; CELL LINE; CHROMOSOME ABERRATIONS; DEAD-BOX RNA HELICASES; DNA DAMAGE; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION; GENES, P53; GENETIC COMPLEMENTATION TEST; HUMANS; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; RADIATION TOLERANCE; RNA HELICASES; RNA NUCLEOTIDYLTRANSFERASES; RNA, MESSENGER; TRANSFECTION;

EID: 0029972581     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096145940     Document Type: Article

References (60)

1. AKASHI, M., SHAW, G., GROSS M., SAITO, M. and KOEFFLER, H. P., 1991, Role of AUUU sequences in stabilization of granulocyte-macrophage colony-stimulating factor RNA in stimulated cells. Blood, 78, 2005-2012.
2. BEAMISH, H. and LAVIN, M. F., 1994, Radiosensitivity in ataxia-telangiectasia: anomalies in radiation induced cell cycle delay. International Journal of Radiation Biology, 65, 175-184.
3. BELT, P. B., GROENEVELT, G. M., TEUBEL, H., VAND DE PUTTE, W. J. and BACKENDORF, C., 1989, Construction and properties of an Epstein-Barr virus-derived cDNA expression vector for human cells. Gene, 84, 407-417.
4. BOHR, V. A., PHILLIPS, D. H. and HANAWALT, P. C., 1987, Heterogeneous DNA damage and repair in the mammalian genome. Cancer Research, 47, 6426-6436.
5. BOOTHMAN, D. A., WANG, M. and LEE, S. W., 1991, Induction of tissue-type plasminogen activator by ionising radiation in human malignant melanoma cells. Cancer Research, 51, 5587-5595.
6. CAPUT, D., BEUTLER, B., HARTOG, K., THAYER, R., BROWN-SHIMER, S. and CERAMI, A., 1986, Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proceedings of the National Academy of Sciences, USA, 83, 1670-1674.
7. CASEY, J. L., KOELLER, D. M., RAMIN, V. C., KLAUSNER, R. D. and HARFORD, J. B., 1989, Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. EMBO Journal, 8, 3693-3699.
8. CHEN, C. -Y. A. and SHYU, A., 1994, Selective degradation of early-response-gene mRNAs: function analysis of sequence features of the AU-rich elements. Molecular and Cellular Biology, 14, 8471-8482.
9. CHEN, P., FARRELL, A., HOBSON, K., GIRJES, A. and LAVIN, M., 1994, Comparative study of radiation-induced G2 phase delay and chromatid damage in families with ataxia-telangiectasia. Cancer Genetics and Cytogenetics, 76, 43-46.
10. CHEN, P., IMRAY, F. P. and KIDSON, C., 1984, Gene dosage and complementation analysis of ataxia-telangiectasia lymphoblastoid cell lines assayed by induced chromosomal aberrations. Mutation Research, 129, 165-172.
11. CHEN, P., LAVIN, M. F., KIDSON, C. and MOSS, D. J., 1978, Identification of ataxia-telangiectasia heterozygotes: a cancer prone population. Nature, 274, 484-486.
12. DOWER, W. J., MILLER, J. F. and REGSDALE, C. W., 1988, High efficiency transformation of E. coli by voltage electroporation. Nucleic Acids Research, 16, 6127-6135.
13. FORD, M. D., MARTIN, L. and LAVIN, M. F., 1984, The effects of ionising radiation on cell cycle progression in ataxia-telangiectasia. Mutation Research, 125, 115-122.
14. FORNACE, A. J., 1992, Mammalian genes induced by radiation: activation of genes associated with growth control. Annual Review of Genetics, 26, 507-526.
15. FORNACE, A. J. and LITTLE, J. B., 1977, DNA crosslinking induced by X-rays and chemical agents. Biochmica et Biphysica Acta, 477, 343-355.
16. GOODWIN, E. B., OKKEMA, P. G., EVANS, T. C. and KIMBLE, J., 1993, Translational regulation of tra-2 by its 3′ untranslated region controls sexual identity in C. elegans. Cell, 75, 329-339.
17. GOTOFF, S. P., AMIRMOKRI, E. and LIEBNER, E. J., 1967, Ataxia-telangiectasia, neoplasia, untoward response to X-irradiation and tuberous sclerosis. American Journal of Diseases of Childhood, 114, 617-625.
18. GREEN, M. H., LOWE, J. E., ARLETT, C. F., HARCOURT, S. A., BURKE, J. F., JAMES, M. R. and LEHMANN, A. R., 1987, A gamma-ray resistant derivative of an ataxia-telangiectasia cell line following DNA-mediated gene transfer. Journal of Cell Science, 6 (suppl.), 127-137.
19. GREENBERG, M. E. and BELASCO, J. G., 1993, Control of the decay of labile proto oncogene and cytokine mRNAs. In J. Belasco and G. Brawerman (ed.), Control of Messenger RNA stability. (Academic, San Diego), pp. 199-218.
20. HALLAHAN, D. E., SUKHATME, V. P., SHERMAN, M. L., VIRUDACHALAM, S., KUFE, D. and WEICHSELBAUM, R. R., 1991, Protein kinase C mediates X-ray inducibility of nuclear signal transducers EGR1 and JUN. Proceedings of the National Academy of Sciences, USA, 88, 2156-2160.
21. HLOCH, P., SCHNIEDNER, G. and STAUL, H., 1990, Complete cDNA sequence of the human p68 protein. Nucleic Acids Research, 18, 3045.
22. 2/M-phase arrest and release in ataxia-telangiectasia and normal cells after exposure to ionizing radiation. Radiation Research, 140, 17-23.
23. HOULDSWORTH, J. and LAVIN, M. F., 1980, Effect of ionizing radiation on DNA synthesis in ataxia-telangiectasia cells. Nucleic Acids Research, 8, 3709-3720.
24. JASPERS, N. G. J. and BOOTSMA, D., 1982, Genetic heterogeneity in ataxia-telangiectasia studied by cell fusion. Proceedings of the National Academy of Sciences, USA, 79, 2641-2644.
25. KASTAN, M. B., ONYEKWERE, O., SIDRANSKY, D., VOGELSTEIN, B. and CRAIG, R. W., 1991, Participation of p53 protein in the cellular response of DNA damage. Cancer Research, 51, 6304-6311.
26. KASTAN, M. B., ZHAN, O., EI-DEIRY, W. S., CARRIER, F., JACKS, T., WALSH, W. V., PLUNKETT, B. S., VOGELSTEIN, B. and FORNACE, A. J., 1992, A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell, 71, 587-597.
27. KHANNA, K. K. and LAVIN, M. F., 1993, Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia. Oncogene, 8, 3307-3312.
28. KIDSON, C., CHEN, P. and IMRAY, P., 1982, Ataxia-telangiectasia heterozygotes: dominant expresion of ionising radiation sensitive mutant In: Ataxia-telangiectasia - A Cellular and Molecular Link Between Cancer, Neuropathology and Immune Deficiency. Edited by: B. A. Bridges and D. G. Harnden (Wiley: Chichester) pp. 363-372.
29. KLAUSNER, R. D., RONAULT, T. A. and HARFORD, J. B., 1993, Regulating the fate of mRNA: the control of cellular iron metabolism. Cell, 72, 19-28.
30. KONDO, N., INOUE, R., NISHIMURA, S., KASAHARA, K., KAMEYAMA, Y., MIWA, Y., LORENZO, P. R. and ORH, I. T., 1993, Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia. Scandanavian Journal of Immunology, 38, 45-48.
31. KRAMER, M., STEIN, B., MAI, S., KUNZ, E., KOINIG, H., LOFERER, H., GRUNICKE, H. H., PONTA, H., HERRLICH, P. and RAHMSDORF, H. J., 1990, Radiation-induced activation of transcription factors in mammalian cells. Radiation Environmental Biophysics, 29, 303-313.
32. LAGNADO, C. A., BROWN, C. Y. and GOODALL, G. J., 1994, AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA (U/A) (U/A). Molecular and Cellular Biology, 14, 7984-7995.
33. LEE, R. C., FEINBAUM, R. and AMBROS, V., 1993, The C. elegans heterochionic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75, 843-854.
34. LEGERSKI, R. and PETERSON, C., 1992, Expression cloning of a human DNA repair gene involved in xeroderma pigmentosum group C. Nature, 359, 70-73.
35. LEVINE, T. D., GAO, F., KING, P. H., ANDREWS, L. G. and KEENE, J. D., 1993, Hel-N1: an autoimmune RNA-binding protein with specificity for 3′uridylate-rich untranslated regions of growth factor mRNA. Molecular and Cellular Biology, 13, 3494-3504.
36. MEYN, M. S., LU-KUO, J. M. and HERZING, L. B. K., 1993, Expression cloning of multiple human cDNAs that complement the phenotypic defects of ataxia-telangiectasia group D fibroblasts. American Journal of Human Genetics, 53, 1206-1216.
37. MORGAN, J. L., HOLCOMB, T. M. and MORRISSEY, R. W., 1968, Radiation reaction in ataxia-telangiectasia. American Journal of Diseases of Childhood, 116, 557-558.
38. MURNANE, J. P., and PAINTER, R. B., 1982, Complementation of the defects in DNA synthesis in irradiated and unirradiated ataxia-telangiectasia cells. Proceedings of National Academy of Sciences, USA, 79, 1960-1963.
39. NANBU, R., MENOUD, P. A. and NAGAMINE, Y., 1994, Multiple instability-regulating sites in the 3′-untranslated region of the urokinase-type plasminogen activator mRNA. Molecular and Cellular Biology, 14, 4920-4927.
40. NISHIZUKA, Y., 1992, Intracellular signaling by hydrolysis of phospolipids and activation of protein kinase C. Science, 258, 607-614.
41. NOWAK, R., 1994, Mining treasures from 'Junk DNA'. Science, 263, 608-610.
42. PAINTER, R. B., 1985, Inhibition and recovery of DNA synthesis in human cells after exposure to ultraviolet light. Mutation Research, 145, 63-69.
43. PAINTER, R. B. and YOUNG, B. R., 1980, Radiosensitivity in ataxia-telangiectasia: a new explanation. Proceedings of the National Academy of Sciences, USA, 77, 7315-7317.
44. PATERSON, M. C. and SMITH, P. J., 1979, Ataxia-telangiectasia: an inherited disorder involving hypersensitive to ionizing radiation and related DNA-damaging chemicals. Annual Review of Genetics, 13, 291-318.
45. RASTINEJAD, F. and BLAU, H. M., 1993, Genetic complementation reveals a novel regulatory role for 3′untranslated regions in growth and differentiation. Cell, 72, 903-917.
46. RASTINEJAD, F., CONBOY, M. J., TANDO, T. A. and BLAU, H. M., 1993, Tumor suppression by RNA from 3′untranslated region of γ-tropomyocin. Cell, 75, 1107-1117.
47. SAVITSKY, K., BAR-SHIRA, A., GILAD, S., ROTMAN, G., ZIV, Y., VANAGAITE, L., TAGLE, D. A., et al., 1995, A single ataxia-telangiectasia gene with a product similar to PI-3 kinase. Science, 268, 1749-1753.
48. SINGH, S. P. and LAVIN, M. F., 1990, DNA-binding protein activated by gamma radiation in human cells. Molecular and Cellular Biology, 10, 5279-5285.
49. STRATHDEE, C. A., GAVISH, H., SHANNON, W. R. and BUCHWALD, M., 1992, Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature, 356, 763-767.
50. TAYLOR, A. M. R., HARNDEN, D. G., ARLETT, C. F., HARCOURT, A. R., LEHMANN, A. R., STEVENS, S. and BRIDGES, B. A., 1975, Ataxia-telangiectasia: a human mutation with abnormal radiation sensitivity. Nature, 258, 427-429.
51. 0 cells a consequence of defective repair? Nature, 260, 441-443.
52. UCKUN, F. M., SCHIEVEN, G. L., TUEL-AHLGREN, L. M., DIBIRDIK, I., MYERS, D. E., LEDBETTER, J. A. and SONG, G. W., 1993, Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors. Proceedings of the National Academy of Sciences, USA, 90, 252-256.
53. UENO, S., KOTANI, Y., KONDOH, K., SANO, A., KAKIMOTO, Y. and CAMPAGNONI, A. T., 1994a, The 3′-untranslated region of mouse myelin basic protein gene increases the amount of mRNA in immortalized mouse oligodendrocytes. Biochemical and Biophysical Research Communications, 204, 1352-1357.
54. UENO, S., HANDLEY, V. W., BYRAVAN, S. and CAMPAGNONI, A. T., 1994b, Structural feature of myelin basic protein mRNAs inflence their translational efficiencies. Journal of Neurochemistry, 62, 1254-1259.
55. WARD, J. F., 1975, Molecular mechanisms of radiation-induced damage to nucleic acids. Advances in Radiation Biology, 5, 181-239.
56. WARD, J. F., 1981, Some biochemical consequences of the spatial distribution of ionising radiation-produced free radicals. Radiation Research, 86, 185-195.
57. WICKENS, M. and TAKAYAMA, K., 1994, Deviants or emissaries. Nature, 367, 17-18.
58. WIGHTMAN, B., HA, I. and RUVKIN, G., 1993, Post-transcriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegant. Cell, 75, 855-862.
59. YOU, Y., CHEN, G. A. and SHYN, A. B., 1992, U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3 untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation. Molecular and Cellular Biology, 12, 2931-2940.
60. ZIV, Y., BAR-SHIRA, A., JORGENSEN, T., RUSSELL, P. S., SARTIEL, A., SHOWS, T. B., EDDY, R. L., BUCHWALD, M., LEGERSKI, R., SCHIMKE, R. T. and SHILOH, Y., 1995, Human cDNA clones that modify radiomimetic sensitivity of ataxia-telangiectasia (Group A) cells. Somatic Cell and Molecular Genetics, 21, 99-111.