Splenic hypofunction in cirrhosis is not associated with increased risk for infections

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 3, 1996, Pages 257-260

  Levi, Diana ^a   Mauriño, Eduardo ^a   Abecasis, Raquel ^a   Mazure, Roberto ^a   Sugai, Emilia ^a   Boer, Luis ^a   Bai, Julio ^a   Terg, Rubén ^a  

^a HOSPITAL DE GASTROENTEROLOGÍA DR CARLOS BONORINO UDAONDO   (Argentina)

Author keywords

Cirrhosis; Hyposplenism; Infection; Pitted cells

Indexed keywords

ADULT; ALCOHOL LIVER DISEASE; ARTICLE; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE COUNT; FEMALE; HUMAN; HUMAN CELL; INFECTION RISK; LIVER CIRRHOSIS; LIVER FUNCTION; MALE; MORTALITY; PRIORITY JOURNAL; RETICULOCYTE COUNT; SPLEEN FUNCTION; THROMBOCYTE COUNT;

EID: 0029972567     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199603000-00013     Document Type: Article

References (20)

1. Levi D, Terg R, Podesta A, Abecasis R, De Glee G, Rafaelli C: Infecciones bacterianas en el paciente cirrotico. Gastroenterol Hepatol 1989, 12: 26-32.
2. Rimola A, Bory F, Planas R, Xaubet A, Bruguera M, Rodes J: Infecciones bacterianas agudas en la cirrosis hepatica. Gastroenterol Hepatol 1981, 4 : 453-458.
3. Wyke R: Problems of bacterial infection in patients with liver disease. Gut 1987, 28:623-641.
4. Caly W, Strauss E: A prospective study of bacterial infections in patients with cirrhosis. J Hepatol 1993, 18: 353-358.
5. Rimola A, Soto R, Bory F, Arroyo V, Piera C, Rodes J: Reticuloendothelial system phagocytosis in cirrhosis and its relation to bacterial infections and prognosis. Hepatology 1984, 4:53-58.
6. Rajkovk I, Williams R: Abnormalities of neutrophil phagacytosis, intracellular killing and metabolic activity in alcoholic cirrhosis and hepatitis. Hepatology 1986, 6:252-262.
7. De Meo A, Andersen B: Defective chemotaxis associated with a serum inhibitor in cirrhotic patients. New Engl J Med 1972, 286:735-740.
8. Finlayson N, Krohn K, Fanconnet M, Anderson K: Significance of serum complement level in chronic liver disease. Gastroenterology 1972, 63: 653-659.
9. Runyon B: Patients with deficient ascitic fluid opsonic activity are predisposed to spontaneous bacterial peritonitis. Hepatology 1988, 8:632-635.
10. Muller AF, Toghill PJ: Splenic function in alcoholic liver disease. Gut 1992, 33:1386-1389.
11. Ferguson A: Hazards of hyposplenism. Br Med J 1982, 285:1375-1376.
12. Corazza GR, Bullen AW, Hall R, Robinson PJ, Losowsky MS: Simple method of assessing splenic function in coeliac disease. Clin Sci 1981, 60:109-113.
13. Bullen AW, Hall R, Gowland G, Rajah S, Losowsky MS: Hyposplenism, adult coeliac disease and autoimmunity. Gut 1980, 21:28-33.
14. Ryan FP, Smart RC, Preston FE, Holdsworth CD: Hyposplenism in ulcerative colitis. Lancet 1974, II: 318-320.
15. Ryan FP, Smart RC, Holdsworth CD, Preston FE: Hyposplenism in inflammatory bowel disease. Gut 1978, 19:50-55
16. Trewby PN, Chipping PM, Palmer SJ, Roberts PD, Lewis SM, Stewart GS: Splenic atrophy in adult coeliac disease: is it reversible? Gut 1981, 22:628-632.
17. Sills R, Oski F: RBC surface pits in the sickle hemoglobinopathies. Am J Dis Child 1979, 133:526-527.
18. Bullen AW, Losowsky MS: Consequences of impaired splenic function. Cli Sci 1979, 57:129-137.
19. Robertson DA, Bullen AW, Hall R, Losowsky M.S: Blood film appearance in the hyposplenism of coeliac disease. Br J Clin Prac 1983, 37:19-22.
20. Muller AF, Toghill PJ: Functional hyposplenism in alcoholic liver disease: a toxic effect of alcohol? Gut 1994, 35:679-682.