Fibroblast growth factor and its implications for developing and regenerating neurons

International Journal of Developmental Biology

Volumn 40, Issue 1, 1996, Pages 403-410

  Grothe, Claudia ^a   Wewetzer, Konstantin ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

FGF; Motoneurons; Neurotrophic factor; Sensory neurons

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; HEPARIN BINDING PROTEIN; NEUROTRANSMITTER;

ARTICLE; BRAIN STEM; MOTONEURON; NERVE CELL DIFFERENTIATION; NERVE FIBER TRANSECTION; NERVE REGENERATION; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY GANGLION; SENSORY NERVE CELL; SPINAL CORD MOTONEURON; TISSUE DISTRIBUTION;

ANIMALS; FIBROBLAST GROWTH FACTORS; MODELS, NEUROLOGICAL; NERVE REGENERATION; NERVOUS SYSTEM; NEURONS; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR; RNA, MESSENGER;

EID: 0029972503     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (86)

1. ARAKAWA, Y., SENDTNER, M. and THOENEN, H. (1990). Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines J Neurosci. 10: 3507-3515.
2. BAIRD, A. (1994) Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factors. Curr Opin. Neurobiol. 4:78-86.
3. BAIRD, A. and KLAGSBRUN, M. (1991). The fibroblast growth factor family. Cancer Cells 3:239-243.
4. BARBIN, G , MANTHORPE, M. and VARON, S (1984). Purification of chick eye ciliary neuronotrophic factor J. Neurochem. 43: 1468-1478.
5. BARDE, Y-A. (1988). What, if anything, is a neurotrophic factor? Trends Neurosci 11 343-346
6. BEAN, A J., ELDE, R, CAO, Y., OELLIG, C., TAMMINGA, C, GOLDSTEIN, M., PETTERSSON, R.F. and HÒKFELT, T. (1991) Expression of acidic and basic fibroblast growth factors in the substantia nigra of rat monkey and human. Proc. Natl. Acaa Sci. USA 88: 10237-10241
7. BERNFIELD, M., KOKENYESI, R , KATO, M., HINKES, M.T., SPRING, J., GALLO, R.L. and LOSE, E.J. (1992). Biology of the syndecans, a family of transmembrane heparan sulfate proteoglycans. Annu. Rev. Cell Biol. 8. 365-393.
8. BÖHLEN, P. (1989) Fibroblast growth factor In Macrophage-derived Cell Regulatory Factors. Cytokines, Vol. 1 (Ed. C. Sorg). Karger, Basel, pp. 204-228.
9. CATTANEO, E. and McKAY, R. (1990). Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature 347: 762-765.
10. CHIU, A.Y., CHEN, E.W. and LOERA, S. (1994) Distinct neurotrophic responses of axotomized motor neurons to BDNF in adult rats. NeuroReport 5. 693-696.
11. CLATTERBUCK, R.E., PRICE, D L and KOLIATSOS, V.W. (1994). Further characterization of the effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on axotomized neonatal and adult mammalian motor neurons. J. Comp. Neurol. 342: 45-56.
12. CORDON-CARDO, C., TAPLEY, P, JING, S., NANDURI, V., O'ROURKE, E, LAMBALLE, F., KOVARY, K., KLEIN, R., JONES, K.R., REICHHARDT, L F and BARBACID, M. (1991). The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell 66:173-183.
13. COWAN, W M. (1982) A synoptic view of the development of the vertebrate central nervous system. Life Sci. Res. Rep. 24: 7-24.
14. DAVIES, A.M. (1992) Cell death and the trophic requirements of developing sensory neurons In Sensory Neurons (Ed. S A) Oxford University Press, London, pp. 194-214
15. DELLI BOVI, P, CURATOLA, A.M., KERN, F G , GRECO, A, ITTMAN, M and BASILICO, C (1987). An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family. Cell 50: 729-737.
16. DESPRES, G., JALENQUES, I. and ROMAND, R. (1991). Basic FGF-like protein in the lower stato-acoustic system of the neonatal and adult rat. NeuroReport 2: 639-642.
17. DICKSON, C. and PETERS, G. (1987) Potential oncogene product related to growth factors. Nature 326:833.
18. EIDE, F, LOWENSTEIN, D.H. and REICHARDT, L.F. (1993). Neurotrophins and their receptors - current concepts and implication for neurologic disease. Exp. Neurol 121 200-214
19. ELDE, R , CAO, Y., CINTRA, A., BRELJE, TC., PELTO-HUIKKO, M., JUNTTILA, T., FUXE, K., PETTERSON, R.F and HÖKFELT, T (1991). Prominent expression of acidic fibroblast growth factor in motor and sensory neurons Neuron 7: 349-364.
20. FERGUSON, I.A, SCHWEITZER, J.B. and JOHNSON Jr., E.M. (1990). Basic fibroblast growth factor: receptor-mediated mternalization, metabolism, and anterograde axonal transport in retinal ganglion cells, J. Neurosci. 10: 2176-2189.
21. FINCH, P.W., RUBIN, J.S., MIKI, T, RON, D. and AARONSON, S.A. (1989). Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 245: 752-755.
22. FLORKIEWICZ, R., BAIRD, A., and GONZALEZ, A.M (1991). Multiple forms of bFGF: differential nuclear and cell surface localization Growth Factors 4: 265275
23. GIVOL, D. and YAYON, A. (1992) Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. FASEB J 6: 3362-3369
24. GOMEZ-PINILLA, F, LEE, J.W-K. and COTMAN, C.W. (1992). Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbriafornix transection J Neurosci. 12: 345-355.
25. GROTHE, C. and JANET, T (1993) Regulation of FGF-2 and high-affinity FGF-receptor in spinal ganglia and peripheral nerve after lesion. Abstr. Soc. Neurosci 19: 709.7.
26. GROTHE, C and JANET. T. (1995). Expression of FGF-2 and FGF receptor in the adult rat brainstem effect of colchicine J. Comp. Neurol. 353: 18-24
27. GROTHE, C. and MEISINGER, C. (1995) Fibroblast growth factor (FGF)-2 sense and antisense mRNA and FGF receptor type 1 mRNA are present in the embryonic and adult rat nervous system: specific detection by nuclease protection assay Neurosci Lett 197. 175-178
28. GROTHE, C and UNSICKER, K. (1992). Basic fibroblast growth factor in the hypoglossal system: specific retrograde transport, trophic and lesion-related responses. J. Neurosci Res 32: 317-328.
29. GROTHE, C., WEWETZER, K., LAGRANGE, A. and UNSICKER, K. (1991a). Effects of basic fibroblast growth factor on survival and choline acetyltransferase development of spinal cord neurons Dev. Brain Res. 62:257-261.
30. GROTHE, C., ZACHMANN, K. and UNSICKER, K. (1991b). Basic FGF-like immunoreactivity in the developing and adult rat brain stem. J Comp. Neurol. 305. 328-336
31. HEFTI, F., HARTIKKA, J. and KNUSEL, B. (1989). Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurode-generative diseases. Neurobiol Aging 10: 515-533.
32. HENDERSON, C.E., CAMU, W., METTLING, C., GOUIN, A, POULSEN, K., KARIHALOO, M., RULLAMAS, J., EVANS, T, MCMAHON, S.B., ARMANINI, M.P. and ROSENTHAL, A (1993) Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363:266-270.
33. HUGHES, R.A , SENDTNER, M , GOLDFARB, M., LINDHOLM, D. and THOENEN, H. (1993a). Evidence that fibroblast growth factors is a major muscle-derived survival factor for cultured spinal motoneurons. Neuron 10. 369-377.
34. HUGHES R.A, SENDTNER, M. and THOENEN, H. (1993b) Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J. Neurosci. Res. 36:663-671
35. IP, N.Y, STITT, T.N , TAPLEY, P., KLEIN, H., GLASS, D.J., FANDL, J., GREENE, L.A., BARBACID, M. and YANCOPOULOS, G.D. (1993). Similarities and differences in the way neurotrophins interact with the Trks in neuronal and non-neuronal cells. Neuron 10:137-149.
36. JAYE, M., SCHLESSINGER, J. and DIONNE, C.A. (1992). Fibroblast growth factor receptor tyrosine kinases' molecular analysis and signal transduction Biochim. Biophys. Acta 1135:185-199.
37. JOHNSON, D.E. and WILLIAMS, L.T. (1993). Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer. Res. 60:1-41
38. JOSEPH-SILVERSTEIN, J. CONSIGLI, S A , LYSER, K M, and VER PAULT, C (1989). Basic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors. J. Cell Biol 108. 2459-2466.
39. KARDAMI, E., SPECTOR, D and STROHMANN, R.D. (1985) Myogenic growth factor present in skeletal muscle is purified by heparin affinity chromatography. Proc Natl. Acad Sci USA 82: 8044-8047.
40. KLAGSBRUN, M and BAIRD, A. (1991). A dual receptor system is required for basic fibroblast growth factor activity. Cell 67: 229-231.
41. KOLIATSOS, V.E., CAYOUETTE, M.H., BERKEMEIER, L.R., CLATTERBUCK, R E., PRICE, D L. and ROSENTHAL, A. (1994). Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons Proc. Natl. Acad. Sci. USA 91: 3304-3308.
42. KORSCHING, S (1993) The neurotrophic factor concept: a reexamination. J. Neurosci. 13:2739-2748.
43. LEVI-MONTALCINI, R (1987). The nerve growth factor 35 years later. Science 237:1154-1162
44. LIN, L-FH., MISMER, D , LILE, J.D., ARMES, L G., BUTLER III, E.T., VANNICE, J.L. and COLLINS, F. (1989). Purification, cloning, and expression of ciliary neurotrophic factor (CNTF) Science 246:1023-1025.
45. LOUIS, J-C., MAGAL, E , TAKAYAMA, S and VARON, S. (1993). CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death Science 259: 689-692
46. MAISONPIERRE, P.C., BELLUSCIO, L., FREIDMAN, B., ALDERSON, R.F., WIEGAND. S.J , FURTH, M.E., LINDSAY, R.M and YANCOPOULOS, G D. (1990). NT-3, BDNF, and NGF in the developing rat nervous system parallel as well as reciprocal patterns of expression Neuron 5:501-509.
47. MARICS, L, ADELAIDE, J., HAYBAUD, F, MATTEI M-G., COULIER, F., PLANCHE, J., DELAPEY-RIERE, O and BIRNBAUM, D. (1989). Characterization of the HST-related FGF-6 gene, a new member of the fibroblast growth factor gene family. Oncogene 4: 335-340.
48. McMANAMAN, J.L , CRAWFORD, FG., CLARK, R , RICHKER, J and FULLER, F. (1989). Multiple neurotrophic factors from skeletal muscle: demonstration effects of basic fibroblast growth and comparisons with the 22kD choline acetyltransferase development factor J. Neurochem. 63: 1763-1771
49. MIRSKY, R , WINTER, J , ABNEY, E.R., PRUSS, R M., GAVRILOVIC, J. and RAFF, M C. (1980). Myelin-specific proteins and glycolipids in rat Schwann cells and oligodendrocytes in culture J. Cell Biol 84. 483-494
50. MIYAMOTO, M , NARUO, K-I, SEKO, C., MATSUMOTO, S., KONSO, T. and KUROKAWA, T. (1993). Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Mol Cell. Biol 13 4251-4259
51. MORGAN, L., JESSEN, K.R and MIRSKY, R. (1994). Negative regulation of Po gene in Schwann cells: suppression of Po mRNA and protein induction in cultured Schwann cells by FGF2 and TGFβ1, TGFβ2 and TGFβ3. Development 120:1399-1409.
52. MUESCH, A., HARTMANN, E., ROHDE, K., RUBARTELLI, A , SITIA, R and RAPOPORT, T.A. (1990). A novel pathway for secretory proteins? Trends Biochem. 3: 86-88.
53. NURCOMBE, V., FORD, M D , WILDSCHUT, J.A. and BARTLETT, P.F. (1993). Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan. Science 260:103-106.
54. OPPENHEIM, R.W (1989). The neurotrophic theory and naturally occurnng motoneuron death. Trends Neurosci. 12:252-255
55. OPPENHEIM, R W. (1991) Cell death during development of the nervous system. Annu. Rev Neurosci. 14:453-501.
56. OPPENHEIM, R W., PREVETTE, D. and FULLER, F. (1992a). The lack of effect of basic and acidic fibroblast growth factors on the naturally occurring death of neurons in the chick embryo. J. Neurosci. 12: 2726-2734.
57. OPPENHEIM, R.W., PREVETTE, D , QIN-WEI, Y, COLLINS, F. and MacDONALD, J. (1991). Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor. Science 251: 1616-1618
58. OPPENHEIM, R.W., QIN-WEI, Y., PREVETTE, D. and VAN, Q. (1992b). Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 360:755-757.
59. OTTO, D., UNSICKER, K. and GROTHE, C (1987). Pharmacological effects of nerve growth factor and fibroblast growth factor applied to the transectioned sciatic nerve on neuron death in adult dorsal root ganglia. Neurosci. Lett. 83: 156-160.
60. PURVES, D. (1986). The trophic theory of neural connections. Trends Neurosci. 9, 486-489.
61. QIN-WEI, Y., JOHNSON, J., PREVETTE, D. and OPPENHEIM, R.W. (1994). Cell death of spinal motoneurons in the chick embryo following deafferentation: rescue effects of tissue extracts, soluble proteins and neurotrophic agents. J. Neurosci. 14. 7629-7640.
62. SARIOLA, H., SAARMA, M., SAINIO, K., ARUMÄE, U., PALGI, J., VAAHTOKARI, A., THESLEFF, I and KARANOV, A. (1991). Dependence of kidney morphogenesis on the expression of nerve growth factor. Science 254:571-573.
63. SCHECTERSON, L.C. and BOTHWELL, M. (1992) Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons Neuron 9:449-463.
64. SCHNÜRCH, H and RISAU, W (1991). Differentiating and mature neurons express the acidic fibroblast growth factor gene during chick neural development. Development 111. 1143-1154.
65. SENDTNER, M., HOLTMANN, B., KOLBECK, R., THOENEN, H. and BARDE, Y-A (1992). Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360:757-759.
66. SENDTNER, M., KREUTZBERG, G.W. and THOENEN, H. (1990). Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345: 440-441.
67. SNIDER, W.D. (1994). Functions of neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-638.
68. STÖCKLI, K.A., LOTTSPEICH, F, SENDTNER, M., MASIAKOWSKI, P., CARROLL, P., GÖTZ, R., LINDHOLM, D. and THOENEN, H. (1989). Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 342: 920-923.
69. TANAKA, A , MIYAMOTO, K , MINAMINO, N., TAKEDA, M., SATO, B., MATSUO, H. and MATSUMOTO, K. (1992). Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc. Natl. Acad. Sci. USA 89: 8928-8932.
70. TERLAU, H. and SEIFERT, W (1990) Fibroblast growth factor enhances long-term potentiation in the hippocampal slice. Eur. J. Neurosci. 2:973-977
71. THOENEN, H , BANDTLOW, C and HEUMANN, R. (1987). The physiological function of nerve growth factor in the central nervous system: comparison with the periphery. Rev. Physiol. Biochem. Pharmacol. 109:145-179.
72. THOMAS, K.A. (1993). Biochemistry and molecular biology of tibroblast growth factors. In Neurotrophic Factors (Eds. S.E. Loughlin and J.H. Fallon) Academic Press, New York, pp. 258-312.
73. UNSICKER, K., GROTHE, C., LÜDECKE, G., OTTO, D. and WESTERMANN, R. (1993). Fibroblast growth factors, their roles in the central and peripheral nervous system. In Neurotrophic Factors (Eds. S.E. Loughlin and J H. Fallon). Academic Press, New York, pp. 313-338.
74. UNSICKER, K , GROTHE, C., WESTERMANN, R. and WEWETZER, K. (1992a). Cytokines in neural regeneration Curr. Opin. Neurobiol. 2:671-678.
75. UNSICKER, K., REICHERT-PREIBSCH, H., SCHMIDT, R., LABOURDETTE, G. and SENSENBRENNER. M. (1987). Acidic and basic fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc. Natl. Acad. Sci. USA 84. 5459-5463.
76. UNSICKER, K, REICHERT-PREIBSCH, H and WEWETZER, K. (1992b). Stimulation of neuron survival by basic FGF and CNTF is a direct effect and not mediated by non-neuronal cells: evidence from single cell cultures Dev. Brain Res. 65: 285-288.
77. VALENZUELA, D.M., MAISONPIERRE, P.C., GLASS, D J., ROJAS, E., NUNEZ, L, KONG, Y, GIES, D.R., STITT, T.N., IP, NY. and YANCOPOULOS, G.D. (1993). Alternate forms of rat TrkC with different functional capabilities. Neuron 10. 963-974.
78. WANAKA, A, JOHNSON Jr., E.M. and MILBRANDT, J. (1990). Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron 5:267-281.
79. WANAKA, A., MILBRANDT, J. and JOHNSON, E.M Jr. (1991) Expression of FGF receptor gene in rat development. Development 111:455-468.
80. WEISE, B., JANET, T. and GROTHE, C. (1993). Localization of bFGF and FGF-receptor in the developing nervous system of the embryonic and newborn rat. J. Neurosci. Res. 34:442-453
81. WEISE, B., UNSICKER, K. and GROTHE, C. (1992). Localization of basic fibroblast growth factor in a subpopulation of rat sensory neurons. Cell Tissue Res. 267:125-130.
82. WESTERMANN, R., GROTHE, C. and UNSICKER, K (1990) Basic fibroblast growth factor (bFGF), a multifunctional growth factor for neuroectodermal cells. J Cell Sci. 13 (Suppl.): 97-117.
83. WEWETZER, K, MacDONALD, J.R., COLLINS, F. and UNSICKER, K. (1990) CNTF rescues motoneurons from ontogenic cell death in vivo, but not in vitro. NeuroReport 1: 203-206
84. WHEELER, E.F and BOTHWELL, M. (1992). Spatiotemporal patterns of expression of NGF and the low-affinity NGF receptor in rat embryos suggest functional roles in tissue morphogenesis. J. Neurosci. 12: 930-945.
85. WRIGHT, E M., VOGEL, K.S. and DAVIS, A.M. (1992). Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival. Neuron 9: 139-150.
86. ZHAN, X , BATES, B. and GOLDFARB, M. (1988). The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors. Mol. Cell Biol. 8: 3487-3497