메뉴 건너뛰기




Volumn 27, Issue 5, 1996, Pages 1108-1114

Doxazosin prevents proteinuria and glomerular loss of heparan sulfate in diabetic rats

Author keywords

adrenergic alpha antagonists; albuminuria; antihypertensive therapy; blood pressure; diabetic nephropathy; rats

Indexed keywords

ALBUMIN; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; DOXAZOSIN; GLYCOSAMINOGLYCAN; GLYCOSYLATED HEMOGLOBIN; HEPARAN SULFATE; INSULIN ZINC SUSPENSION; PROTEOGLYCAN;

EID: 0029972395     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.27.5.1108     Document Type: Article
Times cited : (18)

References (57)
  • 1
    • 0026261554 scopus 로고
    • United States Renal Data System 1991 Annual Data Report
    • United States Renal Data System 1991 Annual Data Report. Am J Kidney Dis. 1991;18(suppl 2):1-127.
    • (1991) Am J Kidney Dis , vol.18 , Issue.2 SUPPL. , pp. 1-127
  • 2
    • 0020529948 scopus 로고
    • The stages in diabetic renal disease: With emphasis on the stage of incipient nephropathy
    • Mogensen CE, Christensen CK, Vittinghus E. The stages in diabetic renal disease: with emphasis on the stage of incipient nephropathy. Diabetes. 1983;32(suppl 2):64-78.
    • (1983) Diabetes , vol.32 , Issue.2 SUPPL. , pp. 64-78
    • Mogensen, C.E.1    Christensen, C.K.2    Vittinghus, E.3
  • 3
    • 0002298081 scopus 로고
    • Diabetes mellitus
    • Heptinstall RH, ed. Boston, Mass: Little. Brown & Co;
    • Olson JL. Diabetes mellitus. In: Heptinstall RH, ed. Pathology of the Kidney. Boston, Mass: Little. Brown & Co; 1992:1715-1763.
    • (1992) Pathology of the Kidney , pp. 1715-1763
    • Olson, J.L.1
  • 5
    • 0020045025 scopus 로고
    • Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus
    • Viberti GC, Jarrett RJ, Mahmud U, Hill RD, Argyropoulos A, Keen H. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet. 1982;1:1430-1432.
    • (1982) Lancet , vol.1 , pp. 1430-1432
    • Viberti, G.C.1    Jarrett, R.J.2    Mahmud, U.3    Hill, R.D.4    Argyropoulos, A.5    Keen, H.6
  • 6
    • 0019944871 scopus 로고
    • Early detection of patients at risk of developing diabetic nephropathy: A longitudinal study of urinary albumin excretion
    • Parving H-H, Oxenboll B, Svendsen PA, Christiansen JS, Andersen AR. Early detection of patients at risk of developing diabetic nephropathy: a longitudinal study of urinary albumin excretion. Acta Endocrinol (Copenh). 1982;100:550-555.
    • (1982) Acta Endocrinol (Copenh) , vol.100 , pp. 550-555
    • Parving, H.-H.1    Oxenboll, B.2    Svendsen, P.A.3    Christiansen, J.S.4    Andersen, A.R.5
  • 7
    • 0021236983 scopus 로고
    • Predicting diabetic nephropathy in insulin-dependent patients
    • Mogensen CE, Christensen CK. Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med. 1984;311:89-93.
    • (1984) N Engl J Med , vol.311 , pp. 89-93
    • Mogensen, C.E.1    Christensen, C.K.2
  • 8
    • 0025334809 scopus 로고
    • Prediction of clinical diabetic nephropathy in IDDM patients: Alternatives to microalbuminuria?
    • Mogensen CE. Prediction of clinical diabetic nephropathy in IDDM patients: alternatives to microalbuminuria? Diabetes. 1990; 39:761-767.
    • (1990) Diabetes , vol.39 , pp. 761-767
    • Mogensen, C.E.1
  • 9
    • 0028144401 scopus 로고
    • Microalbuminuria in non-insulin-dependent diabetes mellitus: Implications for renal survival
    • Abbott KC, Sanders LR, Bakris GL. Microalbuminuria in non-insulin-dependent diabetes mellitus: implications for renal survival. Arch Intent Meet. 1994;154:146-153.
    • (1994) Arch Intent Meet , vol.154 , pp. 146-153
    • Abbott, K.C.1    Sanders, L.R.2    Bakris, G.L.3
  • 10
    • 0027286787 scopus 로고
    • Meta-analysis of effects of intensive blood-glucose control of late complications of type I diabetes
    • Wang PH, Lau J, Chalmers TC. Meta-analysis of effects of intensive blood-glucose control of late complications of type I diabetes. Lancet. 1993;341:1306-1309.
    • (1993) Lancet , vol.341 , pp. 1306-1309
    • Wang, P.H.1    Lau, J.2    Chalmers, T.C.3
  • 11
    • 0029076841 scopus 로고
    • Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial. The Diabetes Control and Complications (DCCT) Trial
    • Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial. The Diabetes Control and Complications (DCCT) Trial. Kidney Int. 1995;47:1703-1720.
    • (1995) Kidney Int , vol.47 , pp. 1703-1720
  • 12
    • 0028944962 scopus 로고
    • Hyperglycemia and microvascular and macrovascular disease in diabetes
    • Klein R. Hyperglycemia and microvascular and macrovascular disease in diabetes. Diabetes Care. 1995;18:258-268.
    • (1995) Diabetes Care , vol.18 , pp. 258-268
    • Klein, R.1
  • 13
    • 0017198837 scopus 로고
    • Progression of nephropathy in long-term diabetics with proteinuria and effect of initial antihypertensive treatment
    • Mogensen CE. Progression of nephropathy in long-term diabetics with proteinuria and effect of initial antihypertensive treatment. Scand J Clin Lab Invest. 1976;36:383-388.
    • (1976) Scand J Clin Lab Invest , vol.36 , pp. 383-388
    • Mogensen, C.E.1
  • 14
    • 0020549706 scopus 로고
    • Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy
    • Parving H-H, Andersen AR, Smidt UM. Svendsen PA. Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy. Lancet. 1983;2:1175-1179.
    • (1983) Lancet , vol.2 , pp. 1175-1179
    • Parving, H.-H.1    Andersen, A.R.2    Smidt, U.M.3    Svendsen, P.A.4
  • 15
    • 0023745583 scopus 로고
    • Early diabetic nephropathy: Detection and prevention
    • Viberti GC, Bending JJ. Early diabetic nephropathy: detection and prevention. Adv Nephrol. 1988;17:101-112.
    • (1988) Adv Nephrol , vol.17 , pp. 101-112
    • Viberti, G.C.1    Bending, J.J.2
  • 16
    • 0023571273 scopus 로고
    • Therapeutic implications of converting-enzyme inhibitors in renal disease
    • Anderson S, Brenner BM. Therapeutic implications of converting-enzyme inhibitors in renal disease. Am J Kidney Dix. 1987;10(suppl 1):81-87.
    • (1987) Am J Kidney Dix , vol.10 , Issue.1 SUPPL. , pp. 81-87
    • Anderson, S.1    Brenner, B.M.2
  • 17
    • 0027243453 scopus 로고
    • Comparative effects of different antihypertensive treatments of progression on diabotic renal disease
    • Slataper R, Vicknair N, Sadler R, Bakris GL. Comparative effects of different antihypertensive treatments of progression on diabotic renal disease. Arch Intern Med. 1993;53:973-980.
    • (1993) Arch Intern Med , vol.53 , pp. 973-980
    • Slataper, R.1    Vicknair, N.2    Sadler, R.3    Bakris, G.L.4
  • 18
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
    • Lewis EJ, Hunsicker LG, Bain RP, Ronde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med. 1993;329:1456-1462.
    • (1993) N Engl J Med , vol.329 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Ronde, R.D.4
  • 19
    • 0027517014 scopus 로고
    • Angiotensin-converting enzyme inhibitors and progression of diabetic nephropathy
    • Bakris GL. Angiotensin-converting enzyme inhibitors and progression of diabetic nephropathy. Ann Intern Med. 1993;118: 643-644.
    • (1993) Ann Intern Med , vol.118 , pp. 643-644
    • Bakris, G.L.1
  • 20
    • 0028011891 scopus 로고
    • Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria
    • Viberti GC, Mogensen CE, Groop LC, Pauls JF. Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. JAMA. 1994; 271:275-279.
    • (1994) JAMA , vol.271 , pp. 275-279
    • Viberti, G.C.1    Mogensen, C.E.2    Groop, L.C.3    Pauls, J.F.4
  • 21
    • 0029029238 scopus 로고
    • Long-term effects of antihypertensive agents on proteinuria and renal function
    • Maki DD, Ma JZ, Louis TA, Kasiske BL. Long-term effects of antihypertensive agents on proteinuria and renal function. Arch Intern Med. 1995;155:1073-1080.
    • (1995) Arch Intern Med , vol.155 , pp. 1073-1080
    • Maki, D.D.1    Ma, J.Z.2    Louis, T.A.3    Kasiske, B.L.4
  • 22
    • 0026315764 scopus 로고
    • Calcium antagonists and diabetic nephropathy
    • Epstein M. Calcium antagonists and diabetic nephropathy. Arch Intern Med. 1991;151:2361-2364.
    • (1991) Arch Intern Med , vol.151 , pp. 2361-2364
    • Epstein, M.1
  • 23
    • 0038777773 scopus 로고
    • Calcium abnormalities and the diabetic, hypertensive patient: Implications for renal preservation
    • Epstein M, ed. Philadelphia, Pa: Hanley & Belfus;
    • Bakris GL. Calcium abnormalities and the diabetic, hypertensive patient: Implications for renal preservation. In: Epstein M, ed. Calcium Antagonists in Clinical Medicine. Philadelphia, Pa: Hanley & Belfus; 1992:367-389.
    • (1992) Calcium Antagonists in Clinical Medicine , pp. 367-389
    • Bakris, G.L.1
  • 24
    • 0026550167 scopus 로고
    • Nifedipine versus fosinopril in uninephrectomized diabetic rats
    • Anderson S, Rennke HG, Brenner BM. Nifedipine versus fosinopril in uninephrectomized diabetic rats. Kidney Int. 1992;41: 891-897.
    • (1992) Kidney Int , vol.41 , pp. 891-897
    • Anderson, S.1    Rennke, H.G.2    Brenner, B.M.3
  • 25
    • 0027160260 scopus 로고
    • Effect of diltiazem on glomerular beparan sulfate and albuminuria in diabetic rats
    • Jyothirmayi GN, Reddi AS. Effect of diltiazem on glomerular beparan sulfate and albuminuria in diabetic rats. Hypertension. 1993;21:795-802.
    • (1993) Hypertension , vol.21 , pp. 795-802
    • Jyothirmayi, G.N.1    Reddi, A.S.2
  • 26
    • 0025908973 scopus 로고
    • Current status of the structural and functional basis of glomerular filtration and proteinuria
    • Kanwar YS, Liu ZZ, Kashihara N, Wallner EI. Current status of the structural and functional basis of glomerular filtration and proteinuria. Semin Nephrol. 1991;11:390-413.
    • (1991) Semin Nephrol , vol.11 , pp. 390-413
    • Kanwar, Y.S.1    Liu, Z.Z.2    Kashihara, N.3    Wallner, E.I.4
  • 29
    • 0019952941 scopus 로고
    • Effect of diabetes on the glycosamino-glycan component of the human glomerular basement membrane
    • Parthasarathy N, Spiro RG. Effect of diabetes on the glycosamino-glycan component of the human glomerular basement membrane. Diabetes. 1982;31:738-741.
    • (1982) Diabetes , vol.31 , pp. 738-741
    • Parthasarathy, N.1    Spiro, R.G.2
  • 30
    • 0019730380 scopus 로고
    • 35S)sulfate incorporation into glomerular basement membrane glycosaminoglycans is decreased in experimental diabetes
    • 35S)sulfate incorporation into glomerular basement membrane glycosaminoglycans is decreased in experimental diabetes. Lab Clin Med. 1981;98:715-722.
    • (1981) Lab Clin Med , vol.98 , pp. 715-722
    • Cohen, M.P.1    Surma, M.L.2
  • 32
    • 2442748185 scopus 로고
    • Decreased de novo synthesis of glomerular proteoglycans in diabetes: Biochemical and auto-radiographic evidence
    • Kanwar YS, Rosenzweig LJ, Linker A, Jakubowski ML. Decreased de novo synthesis of glomerular proteoglycans in diabetes: biochemical and auto-radiographic evidence. Proc Natl Acad Sci U S A. 1983;80:2272-2275.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 2272-2275
    • Kanwar, Y.S.1    Rosenzweig, L.J.2    Linker, A.3    Jakubowski, M.L.4
  • 33
    • 0025337215 scopus 로고
    • Glomerular and urinary glycosaminoglycans in diabetic rats
    • Reddi AS. Glomerular and urinary glycosaminoglycans in diabetic rats. Clin Chim Acta. 1990;189:211-220.
    • (1990) Clin Chim Acta , vol.189 , pp. 211-220
    • Reddi, A.S.1
  • 34
    • 0020043146 scopus 로고
    • Alterations in the basement membrane (heparan sulfate) proteoglycan in diabetic mice
    • Rohrbach DH, Hassell JR, Kleinman HK, Martin GR. Alterations in the basement membrane (heparan sulfate) proteoglycan in diabetic mice. Diabetes. 1982;31:185-188.
    • (1982) Diabetes , vol.31 , pp. 185-188
    • Rohrbach, D.H.1    Hassell, J.R.2    Kleinman, H.K.3    Martin, G.R.4
  • 35
    • 0026030760 scopus 로고
    • Prevention of albuminuria by captopril in diabetic rats
    • Reddi AS. Prevention of albuminuria by captopril in diabetic rats. Gen Pharmacol. 1991;22:323-328.
    • (1991) Gen Pharmacol , vol.22 , pp. 323-328
    • Reddi, A.S.1
  • 36
    • 0026081991 scopus 로고
    • Enalapril improves albuminuria by preventing glomerular loss of heparan sulfate in diabetic rats
    • Reddi AS, Ramamurthi R, Miller M, Dhuper S, Lasker N. Enalapril improves albuminuria by preventing glomerular loss of heparan sulfate in diabetic rats. Biochem Meet Metab Biol. 1991;45: 119-131.
    • (1991) Biochem Meet Metab Biol , vol.45 , pp. 119-131
    • Reddi, A.S.1    Ramamurthi, R.2    Miller, M.3    Dhuper, S.4    Lasker, N.5
  • 38
    • 0001503778 scopus 로고
    • A principle for counting tissue structures on random sections
    • Weibel ER, Gomez DM. A principle for counting tissue structures on random sections. J Appl Physiol. 1962;17:343-348.
    • (1962) J Appl Physiol , vol.17 , pp. 343-348
    • Weibel, E.R.1    Gomez, D.M.2
  • 39
    • 0025302169 scopus 로고
    • Mechanisms of proteinuria in diabetic renal disease
    • Meyer TW. Mechanisms of proteinuria in diabetic renal disease. Semin Nephrol. 1990;10:194-202.
    • (1990) Semin Nephrol , vol.10 , pp. 194-202
    • Meyer, T.W.1
  • 41
    • 0019460233 scopus 로고
    • Glomerular hemodynamics in experimental diabetes
    • Hosteller TH, Troy JL, Brenner BM. Glomerular hemodynamics in experimental diabetes. Kidney Int. 1981;19:410-415.
    • (1981) Kidney Int , vol.19 , pp. 410-415
    • Hosteller, T.H.1    Troy, J.L.2    Brenner, B.M.3
  • 42
    • 0022614124 scopus 로고
    • Pathogenesis of diabetic microangiopathy: The hemodynamic view
    • Zatz R, Brenner BM. Pathogenesis of diabetic microangiopathy: the hemodynamic view. Am J Meet. 1986;80:443-453.
    • (1986) Am J Meet , vol.80 , pp. 443-453
    • Zatz, R.1    Brenner, B.M.2
  • 43
    • 0027225268 scopus 로고
    • Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria
    • Brown SA, Walton CL, Crawford P, Bakris GL. Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria. Kidney Int. 1993;43:1210-1218.
    • (1993) Kidney Int , vol.43 , pp. 1210-1218
    • Brown, S.A.1    Walton, C.L.2    Crawford, P.3    Bakris, G.L.4
  • 44
    • 0026471297 scopus 로고
    • Intraglomerular pressure and mesangial stretching stimulate extra-cellular matrix formation in the rat
    • Riser BL, Cortes P, Zhao X, Bernstein J, Dumler F, Narins RG. Intraglomerular pressure and mesangial stretching stimulate extra-cellular matrix formation in the rat. J Clin Invest. 1992;90: 1932-1943.
    • (1992) J Clin Invest , vol.90 , pp. 1932-1943
    • Riser, B.L.1    Cortes, P.2    Zhao, X.3    Bernstein, J.4    Dumler, F.5    Narins, R.G.6
  • 45
    • 0021365056 scopus 로고
    • Nonenzymatic glycosylation of human serum albumin alters its conformation and function
    • Shaklai N, Garlick RL, Bunn HF. Nonenzymatic glycosylation of human serum albumin alters its conformation and function. J Biol Chem. 1984;259:3812-3817.
    • (1984) J Biol Chem , vol.259 , pp. 3812-3817
    • Shaklai, N.1    Garlick, R.L.2    Bunn, H.F.3
  • 46
    • 0021357455 scopus 로고
    • Glucosyl albumin and diabetic microalbuminuria: Demonstration of an altered renal handling
    • Ghiggeri GM, Candiano G, Delfino G, Bianchini F, Queirolo C. Glucosyl albumin and diabetic microalbuminuria: demonstration of an altered renal handling. Kidney Int. 1984;25:565-570.
    • (1984) Kidney Int , vol.25 , pp. 565-570
    • Ghiggeri, G.M.1    Candiano, G.2    Delfino, G.3    Bianchini, F.4    Queirolo, C.5
  • 47
    • 0027235343 scopus 로고
    • Microalbuminuria in essential hypertension: Reduction by different antihypertensive drugs
    • Erley CM, Haefele U, Heyne N, Braun N, Risler T. Microalbuminuria in essential hypertension: reduction by different antihypertensive drugs. Hypertension. 1993;21:810-815.
    • (1993) Hypertension , vol.21 , pp. 810-815
    • Erley, C.M.1    Haefele, U.2    Heyne, N.3    Braun, N.4    Risler, T.5
  • 48
    • 0026023064 scopus 로고
    • Doxazosin therapy in the treatment of diabetic hypertension
    • Feher MD. Doxazosin therapy in the treatment of diabetic hypertension. Am Heart J. 1991;121:1291-1301.
    • (1991) Am Heart J , vol.121 , pp. 1291-1301
    • Feher, M.D.1
  • 49
    • 0025967050 scopus 로고
    • Doxazosin effects on insulin and glucose in hypertensive patients
    • Lehtonen A. Doxazosin effects on insulin and glucose in hypertensive patients. Am Heart J. 1991;121:1307-1311.
    • (1991) Am Heart J , vol.121 , pp. 1307-1311
    • Lehtonen, A.1
  • 50
    • 0025974696 scopus 로고
    • Effect of antihypertensive drugs on insulin, glucose and lipid metabolism
    • Lithell HOL. Effect of antihypertensive drugs on insulin, glucose and lipid metabolism. Diabetes Care. 1991;14:203-209.
    • (1991) Diabetes Care , vol.14 , pp. 203-209
    • Lithell, H.O.L.1
  • 52
    • 0029044426 scopus 로고
    • 2+ channel antagonists and α-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension
    • 2+ channel antagonists and α-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension. Diabetes. 1995;44: 665-671.
    • (1995) Diabetes , vol.44 , pp. 665-671
    • Giordano, M.1    Matsuda, M.2    Sanders, L.3    Canessa, M.L.4    De Fronzo, R.A.5
  • 53
    • 0026726934 scopus 로고
    • Effect of doxazosin on insulin sensitivity in hypertensive non-insulin dependent diabetic patients
    • Huupponen R, Lehtonen A, Vahatalo M. Effect of doxazosin on insulin sensitivity in hypertensive non-insulin dependent diabetic patients. Eur J Clin Pharmacol. 1992;43:365-368.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 365-368
    • Huupponen, R.1    Lehtonen, A.2    Vahatalo, M.3
  • 54
    • 0028331994 scopus 로고
    • Changes in glucose, insulin, lipid, lipoprotein, and apoprotein concentrations and insulin action in doxazosin-treated patients with hypertension: Comparison between nondiabetic individuals and patients with non-insulin-dependent diabetes mellitus
    • Maheux P, Facchini F, Jeppesen J, Greenfield MS, Clinkingbeard C, Chen YDI, Reaven GM. Changes in glucose, insulin, lipid, lipoprotein, and apoprotein concentrations and insulin action in doxazosin-treated patients with hypertension: comparison between nondiabetic individuals and patients with non-insulin-dependent diabetes mellitus. Am J Hypertens. 1994;7:416-424.
    • (1994) Am J Hypertens , vol.7 , pp. 416-424
    • Maheux, P.1    Facchini, F.2    Jeppesen, J.3    Greenfield, M.S.4    Clinkingbeard, C.5    Chen, Y.D.I.6    Reaven, G.M.7
  • 55
    • 0019280494 scopus 로고
    • Amelioration of mesangial volume and surface alterations following islet transplantation in diabetic rats
    • Steffes MW, Brown DM, Basgen JM, Mauer SM. Amelioration of mesangial volume and surface alterations following islet transplantation in diabetic rats. Diabetes. 1980;29:509-515.
    • (1980) Diabetes , vol.29 , pp. 509-515
    • Steffes, M.W.1    Brown, D.M.2    Basgen, J.M.3    Mauer, S.M.4
  • 56
    • 0024429326 scopus 로고
    • Short and long term effects of antihypertensive therapy in the diabetic rat
    • Anderson S, Rennke HG, Garcia DL, Brenner BM, Short and long term effects of antihypertensive therapy in the diabetic rat. Kidney Int. 1989;36:526-536.
    • (1989) Kidney Int , vol.36 , pp. 526-536
    • Anderson, S.1    Rennke, H.G.2    Garcia, D.L.3    Brenner, B.M.4
  • 57
    • 0028309763 scopus 로고
    • Effects of different anti-hypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs
    • Gaber L, Walton C, Brown S, Bakris G. Effects of different anti-hypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs. Kidney Int. 1994;46; 161-169.
    • (1994) Kidney Int , vol.46 , pp. 161-169
    • Gaber, L.1    Walton, C.2    Brown, S.3    Bakris, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.