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Volumn 118, Issue 28, 1996, Pages 6580-6587

Mechanism of unassisted ion transport across membrane bilayers

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ION TRANSPORT; MEMBRANE STRUCTURE; MEMBRANE TRANSPORT; THERMODYNAMICS;

EID: 0029972071     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9540381     Document Type: Article
Times cited : (138)

References (73)
  • 10
    • 0014481138 scopus 로고
    • (a) Parsegian. V. A. Nature 1969, 221, 844-846.
    • (1969) Nature , vol.221 , pp. 844-846
    • Parsegian, V.A.1
  • 20
    • 0028075424 scopus 로고
    • Lasic, D. D. Liposomes: from Physics to Applications; Elsevier: Amsterdam, New York, 1993. See. also: Science 1994, 265, 316.
    • (1994) Science , vol.265 , pp. 316
  • 38
  • 45
    • 0001057980 scopus 로고
    • Benjamin, I. Science 1993, 261, 1558-1560.
    • (1993) Science , vol.261 , pp. 1558-1560
    • Benjamin, I.1
  • 52
    • 8944236149 scopus 로고    scopus 로고
    • unpublished results
    • Pratt. L. R. unpublished results. The method used is described: Tawa, G. J.; Pratt. L. R. Structure and Reactivity in Aqueous Solution, Characterization of Chemical and Biological Systems; ACS Symposium Series 568; Cramer, C. J., Truhlar, D. G., Eds.; 1994; pp 60-70.
    • Pratt, L.R.1
  • 53
    • 0003129931 scopus 로고
    • Structure and Reactivity in Aqueous Solution, Characterization of Chemical and Biological Systems
    • Cramer, C. J., Truhlar, D. G., Eds.
    • Pratt. L. R. unpublished results. The method used is described: Tawa, G. J.; Pratt. L. R. Structure and Reactivity in Aqueous Solution, Characterization of Chemical and Biological Systems; ACS Symposium Series 568; Cramer, C. J., Truhlar, D. G., Eds.; 1994; pp 60-70.
    • (1994) ACS Symposium Series 568 , pp. 60-70
    • Tawa, G.J.1    Pratt, L.R.2
  • 59
    • 0001663070 scopus 로고
    • + in water predicted by the Zwanzig's theory (Berkowitz, M.; Wan, W. J. Chem. Phys. 1987, 86, 376-382). The position-dependent diffusion constant can also be calculated in molecular dynamics simulations, as described in ref 33. However, for a united atom model of hydrocarbon chains this is not likely to be more accurate than the estimate discussed here.
    • (1992) J. Chem. Phys. , vol.96 , pp. 577-585
    • Benjamin, I.1
  • 60
    • 0001105292 scopus 로고
    • + in water predicted by the Zwanzig's theory (Berkowitz, M.; Wan, W. J. Chem. Phys. 1987, 86, 376-382). The position-dependent diffusion constant can also be calculated in molecular dynamics simulations, as described in ref 33. However, for a united atom model of hydrocarbon chains this is not likely to be more accurate than the estimate discussed here.
    • (1987) J. Chem. Phys. , vol.86 , pp. 376-382
    • Berkowitz, M.1    Wan, W.2
  • 63
    • 8944232946 scopus 로고    scopus 로고
    • note
    • Since, contrary to the assumptions of the transition state theory, not all trajectories of the ion initiated on one side of the bilayer reach the opposite side, P should be multiplied by the transmission coefficient, κ, that corrects for this fact. In the simplest model, (a) the trajectory is reactive (leads to a successful ion transfer) only if it is accompanied by a fluctuation defect on the outgoing side of the membrane, and (b) the probabilities of finding a defect on either side of the membrane are identical. Then κ = 0.5.
  • 73
    • 8944234417 scopus 로고    scopus 로고
    • unpublished results
    • Tawa, G. J.; L. R. Pratt, unpublished results. For description of the method used see ref 34. For the geometry of the system used to calculate ΔA(TS) in eq 1, the electrostatic energy is expected to be approximately 2 kcal/mol lower.
    • Tawa, G.J.1    Pratt, L.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.