Phosphoinositide-generated messengers in cardiac signal transduction

Molecular and Cellular Biochemistry

Volumn 157, Issue 1-2, 1996, Pages 5-14

  Van Heugten, Han A A ^a   Eskildsen Helmond, Yvonne E G ^a   De Jonge, Henriette W ^a   Bezstarosti, Karel ^a   Lamers, Jos M J ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

(Patho)physiological implications; Cardiomyocytes; G proteins; Phosphatidylinositol cycle; Phospholipase C; Receptors

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANGIOTENSIN; ENDOTHELIN 1; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTAMINE; ISOENZYME; MUSCARINIC RECEPTOR; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; RECEPTOR SUBTYPE; SEROTONIN; THROMBIN; VASOPRESSIN;

ADRENERGIC STIMULATION; ARTICLE; ENZYME PHOSPHORYLATION; HEART MUSCLE METABOLISM; PATHOPHYSIOLOGY; PHOSPHOINOSITIDE METABOLISM; SECOND MESSENGER; SIGNAL TRANSDUCTION;

EID: 0029971703     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00227875     Document Type: Article

References (88)

1. Mills A, Duggan MJ: Orphan seven transmembrane domain receptors: reversing pharmacology. Trends Pharmacol Sci 14: 394-396, 1993
2. Okazaki H, Ischizaki N, Sakurai T, Kurokaa K, Goto K, Kumada M, Takuwa Y: Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system. Biochem Biophys Res Commun 190: 1104-1109, 1993
3. Ischizaka N, Okazaki H, Kurokawa K, Kumada M, Takuwa Y: Molecular cloning of a novel putative G protein-coupled receptor from rat aortic smooth muscle. Downregulation of the mRNA level by the cAMP messenger pathway. Biochim Biophys Acta 1218: 173-180, 1994
4. 1-adrenoceptors: an overview. Pharmacol Rev 45: 147-175, 1993
5. Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman MP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ, Peter B, Bailey DS: Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologies. J Pharmacol Exp Therap 272: 134-142, 1995
6. 1D. Biochem Biophys Res Commun 200, 1177-1184, 1994
7. 1d mRNAs are present in cardiac myocytes but not in cardiac fibroblasts. Circ Res 75: 796-802, 1994
8. 1A-adrenergic receptor subtype mediates biochemical, molecular and morphologic features of cultured myocardial cell hypertrophy. J Biol Chem 268: 15374-15380, 1993
9. 1-adrenergic agonists in adult rat hearts. Am J Physiol 267: H970-H978, 1994
10. Timmermans PBMWM, Smith RD: Angiotensin II receptor subtypes: selective antagonists and functional correlates. Eur Heart J 15 (Suppl D): 79-85, 1994
11. Gasc J-M, Shanmugam S, Sibony M, Corvol P: Tissue-specific expression of type 1 angiotensin receptor subtypes. An in situ hybridization study. Hypertension 24: 531-537, 1994
12. Matsubara H, Kanasaki M, Murasawa S, Tsukaguchi Y, Nio Y, Inada M: Differential gene expression and regulation of angiotensin II receptor subtypes in rat cardiac fibroblasts and cardiomyocytes in culture. J Clin Invest 93: 1592-1601, 1994
13. Sechi LA, Griffin CA, Grady EF, Kalinyak JE, Schambelan M: Characterization of angiotensin II receptor subtypes in rat heart. Circ Res 71: 1482-1489, 1992
14. Sadoshima J-I, Izumo S: Signal transduction pathways of angiotensin II-induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers. Circ Res 73: 424-438, 1993
15. Lokuta AJ, Cooper C, Gaa ST, Wang HE, Rogers TB: Angiotensin II stimulates the release of phospholipid-derived second messengers through multiple receptor subtypes in heart cells. J Biol Chem 269: 4832-4838, 1994
16. Sakurai T, Yanagisawa M, Masaki T: Molecular characterization of endothelin receptors. Trends Pharmacol Sci 13: 103-108, 1992
17. Simonson MS: Endothelins: multifunctional renal peptides. Physiol Rev 71: 375-411, 1993
18. Luscher TF, Oemar BS, Boulanger CM, Hahn AWA: Molecular and cellular biology of endothelin and its receptors-Part I. J Hypertension 11: 7-11, 1993
19. Luscher TF, Oemar BS, Boulanger CM, Hahn AWA: Molecular and cellular biology of endothelin and its receptors-Part II. J Hypertension 11: 121-126, 1993
20. Suzuki T, Kumazaki T, Mitsui Y: Endothelin-1 is produced and secreted by neonatal rat cardiac myocytes in vitro. Biochem Biophys Res Commun 191: 823-830, 1993
21. Irons CE, Murray SF, Glembotski CG: Identification of the receptor subtype responsible for endothelin-mediated protein kinase C activation and atrial natriuretic factor secretion from atrial myocytes. J Biol Chem 268: 23417-23421, 1993
22. Halil-Dandan R, Merck DT, Lujan JP, Brunton LL: Coupling of the type A Endothelin receptor to multiple responses in adult rat cardiac myocytes. Molec Pharmacol 45: 1183-1190, 1994
23. A-receptors couple to inositol phosphate formation and inhibition of adenylate cyclase in human right atrium. J Cardiovasc Pharmacol 23: 344-347, 1994
24. A receptors in guinea pig atria. Circ Res 76: 284-292, 1995
25. Woodcock EA, Land SL, Andrews RK: A low affinity, low molecular weight endothelin-A receptor present in neonatal rat heart. Clin Exp Pharmacol Physiol 20, 331-334, 1993
26. Bonner TI: The molecular basis of muscarinic receptor diversity. Trends Neurosci 12, 148-151, 1989
27. Gusovsky F, Lueders JE, Kohn EC, Felder CC: Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-γ. An alternative mechanism for cholinergic-induced phosphoinositide breakdown. J Biol Chem 268: 7768-7772, 1993
28. 1 muscarinic receptors increase calcium current and phosphoinositide turnover in guinea-pig ventricular myocytes. J Physiol 471: 41-60, 1993
29. 3 muscarinic acetylcholine receptor is expressed in chick atrium and ventricle. J Biol Chem 269: 25823-25829, 1994
30. Jones LG, Goldstein D, Brown JH: Guanine nucleotide-dependent inositol trisphosphate production in chick heart cells. Circ Res 62: 299-305, 1988
31. Tajima T, Tsuji Y, Brown JH, Pappano AJ: Pertussis toxin-insensitive phosphoinositide hydrolysis, membrane depolarization and positive inotropic effect of carbachol in chick atria. Circ Res 61: 436-445, 1987
32. Chien WW, Mohabir R, Clusin WT: Effect of thrombin on calcium homeostasis in chick embryonic heart cells. Receptor-operated calcium entry with inositol trisphosphate and a pertussis toxin-sensitive G protein as second messengers. J Clin Invest 85, 1436-1443, 1990
33. Glembotski CC, Irons CE, Krown KA, Murray SF, Sprenkle AB, Sei CA: Myocardial α-thrombin receptor activation induces hypertrophy and increases atrial natriuretic factor gene expression. J Biol Chem 268: 20646-20652, 1993
34. Park TH, McHowat J, Wolf RA, Corr PB: Increased lysophosphatidylcholine content induced by thrombin receptor stimulation in adult rabbit cardiac ventricular myocytes. Cardiovasc Res 28: 1263-1268, 1994
35. 2-purinoceptor activation stimulates phosphoinositide hydrolysis and inhibits accumulation of cAMP in cultured ventricular myocytes. Circ Res 70: 477-485, 1992
36. Zheng J-S, Boluyt MO, O'Neill L, Crow MT, Lakatta EG: Extracellular ATP induces immediate-early gene expression but not cellular hypertrophy in neonatal cardiac myocytes. Circ Res 74: 1034-1041, 1994
37. Endoh M, Takanashi M, Norota I: Effects of vasopressin on phosphoinositide hydrolysis and myocardial contractility. Eur J Pharmacol 218, 355-358, 1992
38. Hamamori Y, Yokoyama M, Yamada M, Akita H, Goshima K, Fukuzaki H: 5-Hydroxytryptamine induces phospholipase C-mediated hydrolysis of phosphoinositides through 5-hydroxytryptamine-2 receptors in cultured fetal mouse ventricular myocytes. Circ Res 66: 1474-1483, 1990
39. Brown JH, Martinson JH: Phosphoinositide-generated second messengers in cardiac signal transduction. Trends Cardiovasc Med 2: 209-213, 1992
40. Hattori Y, Gando S, Nagashima M, Kanno M: Histamine receptors mediating a positive inotropic effect in guinea pig and rabbit ventricular myocardium: distribution of the receptors and their possible intracellular coupling processes. Jpn J Pharmacol 65: 327-336, 1994
41. Fantl WJ, Johnson DE, Williams LT: Signalling by receptor tyrosine kinases. Annu Rev Biochem 62: 453-481, 1993
42. Long CS, Henrich CJ, Simpson PC: A growth factor for cardiac myocytes is produced by cardiac myocytes. Cell Regul 2: 1081-1095, 1991
43. Bogoyevitch MA, Glennon PE, Andersson MB, Clark A, Lazou A, Marshall CJ, Parker PJ, Sugden PH: Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signalling cascade in cardiac myocytes. J Biol Chem 269: 1110-1119, 1994
44. Fuller SJ, Johnson DE, Williams LT: Signalling by receptor tyrosine kinases. Annu Rev Biochem 62: 453-481, 1992
45. Donath MY, Zapf J, Eppenberger-Eberhardt M, Froesch ER, Eppenberger HM: Insulin-like growth factor stimulates myofibril development and decreases smooth muscle α-actin of adult cardiomyocytes. Proc Natl Acad USA 91: 1686-1690, 1994
46. Kajstura J, Cheng W, Reiss K, Anversa P: The IGF-1-IGF-1 receptor system modulates myocyte proliferation but not myocyte cellular hypertrophy in vitro. Exp Cell Res 215: 273-283, 1994
47. Neer EJ: Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80: 249-257, 1995
48. Iniguez-Lluhi J, Kleuss C, Gilman AG: The importance of G-protein βγ subunits. Trends Cell Biol 3: 230-236, 1993
49. Neer EJ, Clapham DE Signal transduction through G-proteins in the cardiac myocyte. Trends Cardiovasc Med 2: 6-11, 1992
50. Berridge M: Inositol trisphosphate and calcium signalling. Nature 361: 315-325, 1993
51. Boyer JL, Paterson A, Harden TK: G-protein mediated regulation of phospholipase C. Involvement of G-proteins. Trends Cardiovasc Med 2: 209-213, 1994
52. q α subunit gene family activate phospholipase C-β isoenzymes. J Biol Chem 267: 16044-16047, 1992
53. h7 from bovine heart. J Biol Chem 268: 27390-27397, 1993
54. h: a GTP-binding protein with transglutaminase activity and receptor signalling function. Science 264: 1593-1596, 1994
55. q. FEBS Lett 363: 261-263, 1995
56. Tagikawa M, Sakurai T, Kasuya Y, Abe Y, Masaki T, Goto K: Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors. Eur J Biochem 228: 102-108, 1995
57. Rhee SG, Choi KD: Regulation of inositol phospholipid-specific phospholipase C isoenzymes. J Biol Chem 267: 123939-12396, 1992
58. Jhon D-Y, Lee H-H, Park D, Lee C-W, Lee K-H, Yoo OJ, Rhee SG: Cloning, sequencing, purification, and Gq-dependent activation of phospholipase C-β3. J Biol Chem 268: 6654-6661, 1993
59. Jiang H, Wu D, Simon MI: Activation of phospholipase C β4 by heterotrimeric GTP-binding proteins. J Biol Chem 269: 7593-7596, 1994
60. Van Heugten HAA, Bezstarosti K, Dekkers DHW, Lamers JMJ: Homologous desensitization of the endothelin-1 receptor mediated phosphoinositide response in cultured neonatal rat cardiomyocytes. J Mol Cell Cardiol 25: 41-52, 1993
61. 1-adrenergic agonist- and endothelin-1-evoked phosphoinositide cycle responses in cultured neonatal rat cardiomyocytes. Biochem Biophys Res Commun 203: 422-429, 1994
62. Woodcock EA, Tanner JK, Fullerton M, Kuraja IJ: Differential pathways of inositol phosphate metabolism in intact neonatal rat hearts and isolated cardiomyocytes. Biochem J 281: 683-688, 1992
63. Woodcock EA, Suss MB, Anderson KE: Inositol phosphate release and metabolism in rat left atria. Circ Res 76: 252-260, 1995
64. Fitzgerald M, Anderson KE, Woodcock EA: Inositol 1,4,5-trisphosphate receptor function in neonatal cardiomyocytes. Eur J Pharmacol 268: 275-278, 1994
65. Abdellatif MM, Neubauer CF, Lederer WJ, Roger TB: Angiotensine-induced desensitization of the phosphoinositide pathway in cardiac cells occurs at the level of the receptor. Circ Res 69: 800-809, 1991
66. Van Heugten HAA, De Jonge HW, Goedbloed MA, Bezstarosti K, Sharma HS, Verdouw PD, Lamers JMJ: Intracellular signalling and genetic reprogramming during development of hypertrophy in cultured cardiomyocytes. In: N.S. Dhalla, P.K. Singal, R.E. Beamisch (eds). Heart Hypertrophy and Failure. Kluwer Academic Publishers, Boston, 1995, pp 79-92
67. 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes. J Mol Cell Cardiol 26: 1081-1093, 1994
68. 2+ entry blocker in cultured rat ventricular myocytes. Cell Calcium 18: 515-525, 1995
69. i, and concentration in ventricular myocytes. Am J Physiol 265: H793-H800, 1993
70. i in adult rabbit cardiomyocytes. Circulation 86 (Suppl I): I-218, 1992
71. Endoh M: The effects of various drugs on the myocardial inotropic response. Gen Pharmacol 26: 1-31, 1995
72. McDonough PM, Brown JH, Glembotski CCP: Phenylephrine and endothelin differentially stimulate hydrolysis and ANF expression. Am J Physiol 264: H625-H630, 1993
73. Lamers JMJ, Eskildsen-Helmond YEG, Resink AM, De Jonge HW, Bezstarosti K, Sharma HS, Van Heugten HAA: Endothelin- 1-induced phospholipase C-β and D and protein kinase C isoenzyme signalling leading to hypertrophy in rat cardiomyocytes. J Cardiovasc Pharmacol 26 (suppl. 3): S100-S103, 1995
74. Bogoyevitch MA, Parker PJ, Sugden PH: Characterization of protein kinase C isotype expression in adult rat heart. A protein kinase C-ε is a major isotype present, and it is activated by phorbolesters, epinephrine and endothelin. Circ Res 72: 757-767, 1993
75. Rogers TB, Lokuta AJ: Angiotensin II signal transduction pathways in the cardiovascular system. Trends Cardiovasc Med 4: 110-116, 1994
76. De Jonge HW, Van Heugten HAA, Lamers JMJ: Signal transduction by the phosphatidylinositol cycle in myocardium. J Mol Cell Cardiol 27: 93-106, 1995
77. 2+ in adult rat cardiac myocytes. Circ Res 66: 1143-1155, 1990
78. Speechly-Dick ME, Mocanu MM, Yellon DM: Protein kinase C. Its role in ischemic preconditioning in the heart. Circ Res 75: 586-590, 1994
79. Mitchell MB, Meng X, Ao L, Brown JM, Harken AH, Banerjee, A: Preconditioning of isolated rat heart is mediated by protein kinase C. Circ Res 76: 73-85, 1995
80. Van Heugten HAA, De Jonge HW, Bezstarosti K, Sharma HS, Verdouw PD, Lamers JMJ: Intracellular signalling and genetic reprogramming during agonist-induced hypertrophy of cardiomyocytes. In: W.C. Claycomb, P. Di Nardo (eds). Cardiac growth and regeneration. Annals New York Acad Sci 72: 343-352, 1995
81. Kariya KI, Karns LR, Simpson PC: Expression of a constitutively activated mutant of the β-isozyme of protein kinase C in cardiac myocytes stimulates the promotor of the β-myosin heavy chain. J Biol Chem 266: 10023-10026, 1992
82. Shubeita HE, Martinson EA, Van Bilsen M, Chien KR, Brown JH: Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes. Proc Natl Acad Sci USA 89: 1305-1309, 1992
83. Sei CA, Irons CE, Sprenkle AB, McDonough PM, Brown JH, Glembotski GC: The α-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways. J Biol Chem 266: 15910-15916, 1991
84. Sadoshima J-I, Izumo S: Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J 12: 1681-1692, 1993
85. Kojima M, Shiojima I, Yamazaki T, Komuro I, Yunzeng Z, Yimg W, Mizuno T, Ueki K, Tobe K, Kadowaki T, Nagai R, Yazaki Y: Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signalling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. Circ 89: 2204-2211, 1994
86. A receptor antagonist blocks cardiac hypertrophy provoked by haemodynamic overload. Circ 89: 2198-2203, 1994
87. Ito H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, Nogami A, Marumo F, Hiroe M: Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 92: 398-403, 1993
88. Van Heugten HAA, Bezstarosti K, Lamers JMJ: Endothelin-1 and phenylephrine-induced activation of the phosphoinositide cycle increases cell injury of cultured cardiomyocytes exposed to hypoxia/ reoxygenation. J Mol Cell Cardiol 26: 1513-1524, 1994