Antihypertensive effects of a new transdermal delivery system for clonidine in genetic and experimental hypertensive rats

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 3, 1996, Pages 261-268

  Ishii, Ritsuko ^a   Tagawa, Takeshi ^a   Ishida, Tomoko ^a   Naruse, Tomohiro ^a  

^a Maruho Co   (Japan)

Author keywords

antihypertensive drugs; CAS 4205 90 7; clonidine, transdermal delivery system; M 5041T, pharmacology

Indexed keywords

CLONIDINE; DEOXYCORTICOSTERONE ACETATE; NIFEDIPINE; SODIUM CHLORIDE; TRICHLORMETHIAZIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; HEART RATE; HEREDITARY HYPERTENSION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACEUTICS; RAT; RENOVASCULAR HYPERTENSION; SKIN CONDUCTANCE; SPONTANEOUSLY HYPERTENSIVE RAT; STRATUM CORNEUM; SYSTOLIC BLOOD PRESSURE; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; CLONIDINE; DESOXYCORTICOSTERONE; GALVANIC SKIN RESPONSE; HYPERTENSION; HYPERTENSION, RENOVASCULAR; MALE; NIFEDIPINE; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; TRICHLORMETHIAZIDE;

EID: 0029971419     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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