-
1
-
-
0029148925
-
Abuse of prescription and licit psychoactive substances by the elderly: Issues and recommendations
-
Naranjo CA, Herrmann N, Özdemir V, et al. Abuse of prescription and licit psychoactive substances by the elderly: issues and recommendations. CNS Drugs 1995; 4 (3): 207-21
-
(1995)
CNS Drugs
, vol.4
, Issue.3
, pp. 207-221
-
-
Naranjo, C.A.1
Herrmann, N.2
Özdemir, V.3
-
3
-
-
0026800717
-
Multiple medication use in the elderly: Use of prescription and non-prescription drugs in an Australian community setting
-
Simons LA, Tett S, Simons J, et al. Multiple medication use in the elderly: use of prescription and non-prescription drugs in an Australian community setting. Med J Aust 1992; 157: 242-6
-
(1992)
Med J Aust
, vol.157
, pp. 242-246
-
-
Simons, L.A.1
Tett, S.2
Simons, J.3
-
4
-
-
0025637750
-
Failure to limit quantities of benzodiazepine hypnotic drugs for outpatients: Placing the elderly at risk
-
Short RI, Bauwens SF, Landefeld CS. Failure to limit quantities of benzodiazepine hypnotic drugs for outpatients: placing the elderly at risk. Am J Med 1990; 89: 725-32
-
(1990)
Am J Med
, vol.89
, pp. 725-732
-
-
Short, R.I.1
Bauwens, S.F.2
Landefeld, C.S.3
-
5
-
-
0023836017
-
Development of long term use of psychotropic drugs by general practice patients
-
Mant A, Duncan-Jones P, Saltman D, et al. Development of long term use of psychotropic drugs by general practice patients. BMJ 1988; 296: 251-4
-
(1988)
BMJ
, vol.296
, pp. 251-254
-
-
Mant, A.1
Duncan-Jones, P.2
Saltman, D.3
-
6
-
-
0023835060
-
Prevalence, frequency and duration of hypnotic use among the elderly living at home
-
Morgan K, Dallosso H, Ebrahim S, et al. Prevalence, frequency and duration of hypnotic use among the elderly living at home. BMJ 1988; 296: 601-2
-
(1988)
BMJ
, vol.296
, pp. 601-602
-
-
Morgan, K.1
Dallosso, H.2
Ebrahim, S.3
-
7
-
-
0024269779
-
Use and abuse of benzodiazepines: Issues relevant to prescribing
-
Woods JH, Katz JL, Winger G. Use and abuse of benzodiazepines: issues relevant to prescribing. JAMA 1988; 260: 3476-80
-
(1988)
JAMA
, vol.260
, pp. 3476-3480
-
-
Woods, J.H.1
Katz, J.L.2
Winger, G.3
-
8
-
-
0023141490
-
Psychotropic drug utilization patterns in a metropolitan population
-
Koenig W, Ruther E, Filipiak B. Psychotropic drug utilization patterns in a metropolitan population. Eur J Clin Pharmacol 1987; 32: 43-51
-
(1987)
Eur J Clin Pharmacol
, vol.32
, pp. 43-51
-
-
Koenig, W.1
Ruther, E.2
Filipiak, B.3
-
10
-
-
0022381699
-
Aging and generational effects on drinking behaviors in men: Results from the normative aging study
-
Glynn RJ, Bouchard GR, LoCastro JS, et al. Aging and generational effects on drinking behaviors in men: results from the normative aging study. Am J Public Health 1985; 75: 1413-9
-
(1985)
Am J Public Health
, vol.75
, pp. 1413-1419
-
-
Glynn, R.J.1
Bouchard, G.R.2
LoCastro, J.S.3
-
12
-
-
0021015572
-
Sedative-hypnotic drug use and ageing
-
Morgan K. Sedative-hypnotic drug use and ageing. Arch Gerontol Geriatr 1983; 2: 181-99
-
(1983)
Arch Gerontol Geriatr
, vol.2
, pp. 181-199
-
-
Morgan, K.1
-
13
-
-
0026515661
-
Cognitive improvement following benzodiazepine discontinuation in elderly nursing home residents
-
Salzman C, Fisher J, Nobel K, et al. Cognitive improvement following benzodiazepine discontinuation in elderly nursing home residents. Int J Geriatr Psychiatry 1992; 7: 89-93
-
(1992)
Int J Geriatr Psychiatry
, vol.7
, pp. 89-93
-
-
Salzman, C.1
Fisher, J.2
Nobel, K.3
-
14
-
-
0025042573
-
Problems and pitfalls in the use of benzodiazepines in the elderly
-
Kruse WHH. Problems and pitfalls in the use of benzodiazepines in the elderly. Drug Saf 1990; 5: 328-44
-
(1990)
Drug Saf
, vol.5
, pp. 328-344
-
-
Kruse, W.H.H.1
-
15
-
-
0023803453
-
Benzodiazepine sedatives and the risk of falling in a community-dwelling elderly cohort
-
Sorock GS, Shimkin EE. Benzodiazepine sedatives and the risk of falling in a community-dwelling elderly cohort. Arch Intern Med 1988; 148: 2441-4
-
(1988)
Arch Intern Med
, vol.148
, pp. 2441-2444
-
-
Sorock, G.S.1
Shimkin, E.E.2
-
16
-
-
0024273598
-
Risk factors for falls among the elderly persons living in the community
-
Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among the elderly persons living in the community. N Engl J Med 1988; 319: 1701-7
-
(1988)
N Engl J Med
, vol.319
, pp. 1701-1707
-
-
Tinetti, M.E.1
Speechley, M.2
Ginter, S.F.3
-
17
-
-
0023626486
-
Adverse drug reactions associated with global cognitive impairment in elderly persons
-
Larson EB, Kukull WA, Buchner DA, et al. Adverse drug reactions associated with global cognitive impairment in elderly persons. Ann Intern Med 1987; 107: 169-73
-
(1987)
Ann Intern Med
, vol.107
, pp. 169-173
-
-
Larson, E.B.1
Kukull, W.A.2
Buchner, D.A.3
-
18
-
-
0023093943
-
Psychotropic drug use and the risk of hip fracture
-
Ray W, Griffin M, Schaffner W, et al. Psychotropic drug use and the risk of hip fracture. N Engl J Med 1987; 316: 363-9
-
(1987)
N Engl J Med
, vol.316
, pp. 363-369
-
-
Ray, W.1
Griffin, M.2
Schaffner, W.3
-
19
-
-
0018100104
-
Toxicity of nitrazepam in the elderly: A report from the Boston Collaborative Drug Surveillance Program
-
Greenblatt DJ, Allen MD. Toxicity of nitrazepam in the elderly: a report from the Boston Collaborative Drug Surveillance Program. Br J Clin Pharmacol 1978; 5: 407-13
-
(1978)
Br J Clin Pharmacol
, vol.5
, pp. 407-413
-
-
Greenblatt, D.J.1
Allen, M.D.2
-
21
-
-
0345229609
-
Benzodiazepine kinetics contribute to their differential abuse
-
Busto UE, Lanctot KL, Bremner KE, et al. Benzodiazepine kinetics contribute to their differential abuse. Can J Clin Pharmacol 1995; 2 (1): 23-28
-
(1995)
Can J Clin Pharmacol
, vol.2
, Issue.1
, pp. 23-28
-
-
Busto, U.E.1
Lanctot, K.L.2
Bremner, K.E.3
-
22
-
-
0024380512
-
Dose response relationships in drug dependence in humans
-
Lasagna L, Erill S, Naranjo CA, editors. Amsterdam: Elsevier Science Publishers Biomedical Division
-
Naranjo CA, Busto UE. Dose response relationships in drug dependence in humans. In: Lasagna L, Erill S, Naranjo CA, editors. Dose-response relationships in clinical pharmacology. Amsterdam: Elsevier Science Publishers Biomedical Division, 1989: 79-92
-
(1989)
Dose-response Relationships in Clinical Pharmacology
, pp. 79-92
-
-
Naranjo, C.A.1
Busto, U.E.2
-
23
-
-
0024854201
-
Pharmacokinetic and pharmacodynamic drug interactions: Implications for abuse liability testing
-
Fishman MW, Mello NK, editors. NIDA Res Monogr
-
Sellers EM, Busto U, Kaplan HL. Pharmacokinetic and pharmacodynamic drug interactions: implications for abuse liability testing. In: Fishman MW, Mello NK, editors. Testing for abuse liability of drugs. NIDA Res Monogr 1989; 92: 287-306
-
(1989)
Testing for Abuse Liability of Drugs
, vol.92
, pp. 287-306
-
-
Sellers, E.M.1
Busto, U.2
Kaplan, H.L.3
-
24
-
-
0022633359
-
Pharmacokinetic determinants of drug abuse and dependence: A conceptual perspective
-
Busto U, Sellers EM. Pharmacokinetic determinants of drug abuse and dependence: a conceptual perspective. Clin Pharmacokinet 1986; 11: 144-53
-
(1986)
Clin Pharmacokinet
, vol.11
, pp. 144-153
-
-
Busto, U.1
Sellers, E.M.2
-
25
-
-
0029091638
-
Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism
-
Higuchi S, Matsushita S, Murayaina M, et al. Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism. Am J Psychiatry 1995; 152: 1219-21
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1219-1221
-
-
Higuchi, S.1
Matsushita, S.2
Murayaina, M.3
-
26
-
-
0028832177
-
Cytochrome P450 monooxygenases and interactions of psychotropic drugs: A five-year update
-
Shen WW. Cytochrome P450 monooxygenases and interactions of psychotropic drugs: a five-year update. Int J Psychiatry Med 1995; 25 (3): 277-90
-
(1995)
Int J Psychiatry Med
, vol.25
, Issue.3
, pp. 277-290
-
-
Shen, W.W.1
-
27
-
-
0029125984
-
Metabolism of drugs by cytochrome P450 3A isoforms: Implications for drug interactions in psychopharmacology
-
Von Moltke LL, Greenblatt DJ, Schmider J, et al. Metabolism of drugs by cytochrome P450 3A isoforms: implications for drug interactions in psychopharmacology. Clin Pharmacokinet 1995; 29 Suppl. 1: 33-44
-
(1995)
Clin Pharmacokinet
, vol.29
, Issue.1 SUPPL.
, pp. 33-44
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Schmider, J.3
-
28
-
-
0027724292
-
Triazolam in cirrhosis: Pharmacokinetics and pharmacodynamics
-
Robin DW, Lee M, Hasan SS, et al. Triazolam in cirrhosis: pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 1993; 54: 630-7
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 630-637
-
-
Robin, D.W.1
Lee, M.2
Hasan, S.S.3
-
29
-
-
0026496950
-
The role of individual human cytochromes P450 in drug metabolism and clinical response
-
Cholerton S, Daly AK, Idle JR. The role of individual human cytochromes P450 in drug metabolism and clinical response. Trends Pharmacol Sci 1992; 13: 434-9
-
(1992)
Trends Pharmacol Sci
, vol.13
, pp. 434-439
-
-
Cholerton, S.1
Daly, A.K.2
Idle, J.R.3
-
30
-
-
0026681168
-
P450 enzymes: Inhibition mechanisms, genetic regulation and effects of liver disease
-
Murray M. P450 enzymes: Inhibition mechanisms, genetic regulation and effects of liver disease. Clin Pharmacokinet 1992; 23: 132-46
-
(1992)
Clin Pharmacokinet
, vol.23
, pp. 132-146
-
-
Murray, M.1
-
32
-
-
0024603310
-
Aging and determinants of hepatic drug clearance
-
Vestal RE. Aging and determinants of hepatic drug clearance. Hepatology 1989; 9: 331-4
-
(1989)
Hepatology
, vol.9
, pp. 331-334
-
-
Vestal, R.E.1
-
33
-
-
0023492782
-
Drug metabolism in extrahepatic diseases
-
Farrell GC. Drug metabolism in extrahepatic diseases. Pharmacol Ther 1987; 35: 375-404
-
(1987)
Pharmacol Ther
, vol.35
, pp. 375-404
-
-
Farrell, G.C.1
-
34
-
-
0019522919
-
Human liver aldehyde dehydrogenase in Chinese and Asiatic Indians: Gene detection and the possible implication in alcohol metabolism
-
Teng YS. Human liver aldehyde dehydrogenase in Chinese and Asiatic Indians: gene detection and the possible implication in alcohol metabolism. Biochem Genet 1981; 19: 107-13
-
(1981)
Biochem Genet
, vol.19
, pp. 107-113
-
-
Teng, Y.S.1
-
36
-
-
0027213217
-
Use of benzodiazepines in anxiety disorders
-
Shader RI, Greenblatt DJ. Use of benzodiazepines in anxiety disorders. N Engl J Med 1993; 328: 1398-405
-
(1993)
N Engl J Med
, vol.328
, pp. 1398-1405
-
-
Shader, R.I.1
Greenblatt, D.J.2
-
38
-
-
0017740102
-
Tolerance and dependence after chronic administration of clonidine to the rat
-
Meyer DR, El-Azhary R, Bierer DWS, et al. Tolerance and dependence after chronic administration of clonidine to the rat. Pharmacol Biochem Behav 1977; 7: 227-31
-
(1977)
Pharmacol Biochem Behav
, vol.7
, pp. 227-231
-
-
Meyer, D.R.1
El-Azhary, R.2
Bierer, D.W.S.3
-
39
-
-
0016796611
-
Barbiturate-reinforced responding in rhesus monkeys: Comparison of drugs with different durations of actions
-
Winger GD, Stitzer M, Woods JH. Barbiturate-reinforced responding in rhesus monkeys: comparison of drugs with different durations of actions. J Pharmacol Exp Ther 1975; 195: 505-14
-
(1975)
J Pharmacol Exp Ther
, vol.195
, pp. 505-514
-
-
Winger, G.D.1
Stitzer, M.2
Woods, J.H.3
-
40
-
-
0025830898
-
Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly: Therapeutic considerations (Pt I)
-
Greenblatt DJ, Harmatz JS, Shader RI. Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly: therapeutic considerations (Pt I). Clin Pharmacokinet 1991; 21: 165-77
-
(1991)
Clin Pharmacokinet
, vol.21
, pp. 165-177
-
-
Greenblatt, D.J.1
Harmatz, J.S.2
Shader, R.I.3
-
41
-
-
0026075902
-
Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly: Therapeutic considerations (Pt II)
-
Greenblatt DJ, Harmatz JS, Shader RI. Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly: therapeutic considerations (Pt II). Clin Pharmacokinet 1991; 21: 262-273
-
(1991)
Clin Pharmacokinet
, vol.21
, pp. 262-273
-
-
Greenblatt, D.J.1
Harmatz, J.S.2
Shader, R.I.3
-
42
-
-
0024435591
-
The effect of ageing on the pharmacokinetics of dihydrocodeine
-
Davies KN, Castleden CM, McBurney A, et al. The effect of ageing on the pharmacokinetics of dihydrocodeine. Eur J Clin Pharmacol 1989; 37: 375-9
-
(1989)
Eur J Clin Pharmacol
, vol.37
, pp. 375-379
-
-
Davies, K.N.1
Castleden, C.M.2
McBurney, A.3
-
44
-
-
0029120874
-
Ethanol metabolism and aging: The role of 'first pass metabolism' and gastric alcohol dehydrogenase activity
-
Pozzato G, Moretti M, Franzin F, et al. Ethanol metabolism and aging: the role of 'first pass metabolism' and gastric alcohol dehydrogenase activity. J Gerontol 1995; 50A (3): B135-41
-
(1995)
J Gerontol
, vol.50 A
, Issue.3
-
-
Pozzato, G.1
Moretti, M.2
Franzin, F.3
-
47
-
-
0025909542
-
The ambiguous relation between aging and adverse drug reactions
-
Gurwitz JH, Avorn J. The ambiguous relation between aging and adverse drug reactions. Ann Intern Med 1991; 114: 956-966
-
(1991)
Ann Intern Med
, vol.114
, pp. 956-966
-
-
Gurwitz, J.H.1
Avorn, J.2
-
48
-
-
0024398368
-
Implications of altered drug disposition in the elderly: Studies of benzodiazepines
-
Greenblatt DJ, Shader RI, Harmatz JS. Implications of altered drug disposition in the elderly: studies of benzodiazepines. J Clin Pharmacol 1989; 29: 866-72
-
(1989)
J Clin Pharmacol
, vol.29
, pp. 866-872
-
-
Greenblatt, D.J.1
Shader, R.I.2
Harmatz, J.S.3
-
49
-
-
0023836571
-
Health of long term benzodiazepine users
-
Rodrigo EK, King MB, Williams P. Health of long term benzodiazepine users. BMJ 1988; 296: 603-6
-
(1988)
BMJ
, vol.296
, pp. 603-606
-
-
Rodrigo, E.K.1
King, M.B.2
Williams, P.3
-
52
-
-
0029894677
-
Disposition and first-pass metabolism of ethanol in humans: Is it gastric or hepatic and does it depend on gender?
-
Ammon E, Schafer C, Hofmann U, et al. Disposition and first-pass metabolism of ethanol in humans: is it gastric or hepatic and does it depend on gender? Clin Pharmacol Ther 1996; 59: 503-13
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 503-513
-
-
Ammon, E.1
Schafer, C.2
Hofmann, U.3
-
53
-
-
0015849146
-
Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized
-
Wagner JG. Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized. J Pharmacokinet Biopharm 1973; 1: 165-73
-
(1973)
J Pharmacokinet Biopharm
, vol.1
, pp. 165-173
-
-
Wagner, J.G.1
-
55
-
-
0023760328
-
Frequency of the atypical aldehyde dehydrogenase-2 gene (ALDH2) in Japanese and Caucasians
-
Shibuya A, Yoshida A. Frequency of the atypical aldehyde dehydrogenase-2 gene (ALDH2) in Japanese and Caucasians. Am J Hum Genet 1988; 43: 741-3
-
(1988)
Am J Hum Genet
, vol.43
, pp. 741-743
-
-
Shibuya, A.1
Yoshida, A.2
-
56
-
-
0344934175
-
Aldehyde dehydrogenase inhibitors as alcohol-sensitizing drugs: A pharmacological perspective
-
Brien JF, Loomis CW. Aldehyde dehydrogenase inhibitors as alcohol-sensitizing drugs: a pharmacological perspective. Trends Pharmacol Sci 1985; 6: 478-80
-
(1985)
Trends Pharmacol Sci
, vol.6
, pp. 478-480
-
-
Brien, J.F.1
Loomis, C.W.2
-
57
-
-
0025852722
-
Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men
-
Thomasson HR, Edenberg HJ, Crabb DW, et al. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 1991; 48: 677-81
-
(1991)
Am J Hum Genet
, vol.48
, pp. 677-681
-
-
Thomasson, H.R.1
Edenberg, H.J.2
Crabb, D.W.3
-
58
-
-
0028003869
-
Comparison of long-term benzodiazepine users in three settings
-
Hawley CJ, Tattersall M, Dellaportas C, et al. Comparison of long-term benzodiazepine users in three settings. Br J Psychiatry 1994; 165: 792-6
-
(1994)
Br J Psychiatry
, vol.165
, pp. 792-796
-
-
Hawley, C.J.1
Tattersall, M.2
Dellaportas, C.3
-
59
-
-
0021256584
-
A cross-national comparison of anti-anxiety/sedative drug use
-
Balter MB, Manheimer DI, Mellinger GD, et al. A cross-national comparison of anti-anxiety/sedative drug use. Curr Med Res Opin 1984; 8 Suppl. 4: 5-20
-
(1984)
Curr Med Res Opin
, vol.8
, Issue.4 SUPPL.
, pp. 5-20
-
-
Balter, M.B.1
Manheimer, D.I.2
Mellinger, G.D.3
-
60
-
-
0025352882
-
Kinetic and dynamic components of increased benzodiazepine sensitivity in aging animals
-
Barnhill JG, Greenblatt DJ, Miller LG, et al. Kinetic and dynamic components of increased benzodiazepine sensitivity in aging animals. J Pharmacol Exp Ther 1990; 253: 1153-61
-
(1990)
J Pharmacol Exp Ther
, vol.253
, pp. 1153-1161
-
-
Barnhill, J.G.1
Greenblatt, D.J.2
Miller, L.G.3
-
61
-
-
0021147864
-
Diazepam tolerance: Effect of age. regular sedation, and alcohol
-
Cook PJ, Flanagan R, James IM. Diazepam tolerance: effect of age. regular sedation, and alcohol. BMJ 1984; 289: 351-3
-
(1984)
BMJ
, vol.289
, pp. 351-353
-
-
Cook, P.J.1
Flanagan, R.2
James, I.M.3
-
62
-
-
0021933045
-
Responsiveness to oral diazepam in the elderly: Relationship to total and free plasma concentrations
-
Swift CG, Ewen JM, Clarke P, et al. Responsiveness to oral diazepam in the elderly: relationship to total and free plasma concentrations. Br J Clin Pharmacol 1985; 20: 111-8
-
(1985)
Br J Clin Pharmacol
, vol.20
, pp. 111-118
-
-
Swift, C.G.1
Ewen, J.M.2
Clarke, P.3
-
64
-
-
0026410185
-
Abuse liability assessment of anxiolytics/hypnotics: Rationale and laboratory core
-
Evans SM, Critchfield TS, Griffiths RR. Abuse liability assessment of anxiolytics/hypnotics: rationale and laboratory core. Br J Addict 1991; 86: 1625-32
-
(1991)
Br J Addict
, vol.86
, pp. 1625-1632
-
-
Evans, S.M.1
Critchfield, T.S.2
Griffiths, R.R.3
-
65
-
-
0026410805
-
Utility of subjective-effects measurements in assessing abuse liability of drugs in humans
-
Fischman MW, Foltin RW. Utility of subjective-effects measurements in assessing abuse liability of drugs in humans. Br J Addict 1991; 86: 1563-70
-
(1991)
Br J Addict
, vol.86
, pp. 1563-1570
-
-
Fischman, M.W.1
Foltin, R.W.2
-
67
-
-
0019130292
-
Drug preference and mood in humans: Diazepam
-
Johanson CE, Uhlenhuth EH. Drug preference and mood in humans: diazepam. Psychopharmacology 1980; 71: 269-73
-
(1980)
Psychopharmacology
, vol.71
, pp. 269-273
-
-
Johanson, C.E.1
Uhlenhuth, E.H.2
-
71
-
-
0018407165
-
Human drug self-administration: Double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo
-
Griffiths RR, Bigelow G, Liebson I. Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo. J Pharmacol Exp Ther 1979; 210: 301-10
-
(1979)
J Pharmacol Exp Ther
, vol.210
, pp. 301-310
-
-
Griffiths, R.R.1
Bigelow, G.2
Liebson, I.3
-
72
-
-
0019126543
-
Drug preference in humans: Double-blind comparison of pentobarbital. diazepam, and placebo
-
Griffiths RR, Bigelow GE, Liebson I, et al. Drug preference in humans: double-blind comparison of pentobarbital. diazepam, and placebo. J Pharmacol Exp Ther 1980; 215: 649-61
-
(1980)
J Pharmacol Exp Ther
, vol.215
, pp. 649-661
-
-
Griffiths, R.R.1
Bigelow, G.E.2
Liebson, I.3
-
73
-
-
0021348225
-
Comparison of diazepam and oxazepam: Preference, liking and extent of abuse
-
Griffiths RR, McLeod DR, Bigelow GE, et al. Comparison of diazepam and oxazepam: preference, liking and extent of abuse. J Pharmacol Exp Ther 1984; 229: 501-8
-
(1984)
J Pharmacol Exp Ther
, vol.229
, pp. 501-508
-
-
Griffiths, R.R.1
McLeod, D.R.2
Bigelow, G.E.3
-
74
-
-
0026683081
-
Debrisoquine hydroxylation phenotyping in geriatric psychopharmacology
-
Pollock BG, Perel JM, Altieri LP, et al. Debrisoquine hydroxylation phenotyping in geriatric psychopharmacology. Psychopharmacol Bull 1992; 28: 163-8
-
(1992)
Psychopharmacol Bull
, vol.28
, pp. 163-168
-
-
Pollock, B.G.1
Perel, J.M.2
Altieri, L.P.3
-
75
-
-
0025009831
-
Effects of age and gender on in vitro properties of human liver microsomal monooxygenases
-
Schmucker DL, Woodhouse KW, Wang RK, et al. Effects of age and gender on in vitro properties of human liver microsomal monooxygenases. Clin Pharmacol Ther 1990; 48: 365-74
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 365-374
-
-
Schmucker, D.L.1
Woodhouse, K.W.2
Wang, R.K.3
-
76
-
-
0024241308
-
The effect of age upon the affinity of microsomal monooxygenase enzymes for substrate in human liver
-
Wynne HA, Mutch E, James OFW, et al. The effect of age upon the affinity of microsomal monooxygenase enzymes for substrate in human liver. Age Ageing 1988; 17: 401-5
-
(1988)
Age Ageing
, vol.17
, pp. 401-405
-
-
Wynne, H.A.1
Mutch, E.2
James, O.F.W.3
-
77
-
-
0022197022
-
Aging and drug disposition: An update
-
Schmucker DL. Aging and drug disposition: an update. Pharmacol Rev 1985; 37: 133-48
-
(1985)
Pharmacol Rev
, vol.37
, pp. 133-148
-
-
Schmucker, D.L.1
-
78
-
-
0021705685
-
The effect of age on pathways of drug metabolism in human liver
-
Woodhouse KW, Mutch E, Williams FM, et al. The effect of age on pathways of drug metabolism in human liver. Age Ageing 1984; 13: 328-34
-
(1984)
Age Ageing
, vol.13
, pp. 328-334
-
-
Woodhouse, K.W.1
Mutch, E.2
Williams, F.M.3
-
79
-
-
0029976064
-
Newer antidepressants and the cytochrome P450 system
-
Nemeroff CB, De Vane CL, Pollock BG. Newer antidepressants and the cytochrome P450 system. Am J Psychiatry 1996; 153 (3): 311-20
-
(1996)
Am J Psychiatry
, vol.153
, Issue.3
, pp. 311-320
-
-
Nemeroff, C.B.1
De Vane, C.L.2
Pollock, B.G.3
-
80
-
-
0028898044
-
Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: Potent inhibition by fluvoxamine
-
Rasmussen BB, Maenpaa J, Pelkonen O, et al. Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. Br J Clin Pharmacol 1995; 39 (2): 151-9
-
(1995)
Br J Clin Pharmacol
, vol.39
, Issue.2
, pp. 151-159
-
-
Rasmussen, B.B.1
Maenpaa, J.2
Pelkonen, O.3
-
81
-
-
0028898816
-
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: Comparison with other selective serotonin reuptake inhibitor antidepressants
-
von Moltke LL, Greenblatt DJ, Court MH, et al. Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. J Clin Psychopharmacol 1995; 15: 125-31
-
(1995)
J Clin Psychopharmacol
, vol.15
, pp. 125-131
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Court, M.H.3
-
82
-
-
0028091180
-
A pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluvoxamine
-
Fleishaker JC, Hulst LK. A pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluvoxamine. Eur J Clin Pharmacol 1994; 46: 35-9
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 35-39
-
-
Fleishaker, J.C.1
Hulst, L.K.2
-
83
-
-
0028568243
-
Midazolam should he avoided in patients receiving the systemic antimyeotics ketoconazole or itraconazole
-
Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should he avoided in patients receiving the systemic antimyeotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994; 56: 601-7
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 601-607
-
-
Olkkola, K.T.1
Backman, J.T.2
Neuvonen, P.J.3
-
84
-
-
0028568243
-
Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
-
Varhe A, Olkkola KT, Neuvonen PJ. Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994; 56: 601-7
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 601-607
-
-
Varhe, A.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
85
-
-
0028279667
-
Inhibitors of alprazolam metabolism in vitro: Effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine
-
von Moltke LL, Greenblatt DJ, Cotreau-Bibbo MM, et al. Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine. Br J Clin Pharmacol 1994; 38: 23-31
-
(1994)
Br J Clin Pharmacol
, vol.38
, pp. 23-31
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Cotreau-Bibbo, M.M.3
-
86
-
-
0027167470
-
Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
-
Brosen K, Hansen JG, Nielsen KK, et al. Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine. Eur J Clin Pharmacol 1993; 44: 349-55
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 349-355
-
-
Brosen, K.1
Hansen, J.G.2
Nielsen, K.K.3
-
87
-
-
0027440142
-
Pharmacokinetic drug interactions with antimicrobial agents
-
Gillum JG, Israel DS, Polk RE. Pharmacokinetic drug interactions with antimicrobial agents. Clin Pharmacokinet 1993; 25: 450-82
-
(1993)
Clin Pharmacokinet
, vol.25
, pp. 450-482
-
-
Gillum, J.G.1
Israel, D.S.2
Polk, R.E.3
-
88
-
-
0027456438
-
Inhibition by fluoxetine of cytochrome P450 2D6 activity
-
Otton VS, Dafang W, Russell TJ, et al. Inhibition by fluoxetine of cytochrome P450 2D6 activity. Clin Pharmacol Ther 1993; 53: 401-9
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 401-409
-
-
Otton, V.S.1
Dafang, W.2
Russell, T.J.3
-
89
-
-
0026787192
-
The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes
-
Crewe HK, Lennard MS, Tucker GT, et al. The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol 1992; 34: 262-5
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 262-265
-
-
Crewe, H.K.1
Lennard, M.S.2
Tucker, G.T.3
-
91
-
-
0025760457
-
Pharmacokinetic pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine
-
Lasher TA, Fleishaker JC, Steenwyk RC, et al. Pharmacokinetic pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine. Psychopharmacology 1991; 104: 323-7
-
(1991)
Psychopharmacology
, vol.104
, pp. 323-327
-
-
Lasher, T.A.1
Fleishaker, J.C.2
Steenwyk, R.C.3
-
92
-
-
0024373348
-
Oxidation of midazolam and triazalom by human liver cytochrome P450III A4
-
Kronbach T, Mathys D, Umeno M, et al. Oxidation of midazolam and triazalom by human liver cytochrome P450III A4. Mol Pharmacol 1989; 36: 89-96
-
(1989)
Mol Pharmacol
, vol.36
, pp. 89-96
-
-
Kronbach, T.1
Mathys, D.2
Umeno, M.3
-
93
-
-
0024580554
-
Importance of genetic factors in the regulation of diazepam metabolism: Relationship to S-mephenytoin but not debrisoquine hydroxylation phenotype
-
Bertilsson L, Henthorn TK, Sanz E, et al. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin but not debrisoquine hydroxylation phenotype. Clin Pharmacol Ther 1989; 45: 348-55
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 348-355
-
-
Bertilsson, L.1
Henthorn, T.K.2
Sanz, E.3
-
94
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, et al. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994; 270: 414-23
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
-
95
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquine and S-mephenytoin
-
Bertilsson L, Lou YQ, Du YL, et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquine and S-mephenytoin. Clin Pharmacol Ther 1942; 51: 388-47
-
(1942)
Clin Pharmacol Ther
, vol.51
, pp. 388-447
-
-
Bertilsson, L.1
Lou, Y.Q.2
Du, Y.L.3
-
96
-
-
0022220338
-
Genetic polymorphism of mephenytoin p (4′)-hydroxylation: Difference between Orientals and Caucasians
-
Jurima M, Inaba T, Kadar D, et al. Genetic polymorphism of mephenytoin p (4′)-hydroxylation: difference between Orientals and Caucasians. Br J Clin Pharmacol 1985; 19: 483-7
-
(1985)
Br J Clin Pharmacol
, vol.19
, pp. 483-487
-
-
Jurima, M.1
Inaba, T.2
Kadar, D.3
-
97
-
-
0022178173
-
Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations
-
Nakamura K, Goto F, Ray WA, et al. Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations. Clin Pharmacol 1985; 38: 402-8
-
(1985)
Clin Pharmacol
, vol.38
, pp. 402-408
-
-
Nakamura, K.1
Goto, F.2
Ray, W.A.3
-
98
-
-
10344255850
-
Induction of theophylline metabolism by phenytoin is unaltered by aging
-
Crowley JJ, Cusack BJ, Jue SG, et al. Induction of theophylline metabolism by phenytoin is unaltered by aging. Clin Res 1986; 34: 396A
-
(1986)
Clin Res
, vol.34
-
-
Crowley, J.J.1
Cusack, B.J.2
Jue, S.G.3
-
99
-
-
0021166048
-
Impaired enzyme induction by rifampicin in the elderly
-
Twum-Barima Y, Finnigan T, Habush Al, et al. Impaired enzyme induction by rifampicin in the elderly. Br J Clin Pharmacol 1984; 17: 595-6
-
(1984)
Br J Clin Pharmacol
, vol.17
, pp. 595-596
-
-
Twum-Barima, Y.1
Finnigan, T.2
Al, H.3
-
100
-
-
0018831881
-
Theophylline kinetics in relation to age: The importance of smoking
-
Cusack BJ, Kelly JG, Lavan J, et al. Theophylline kinetics in relation to age: The importance of smoking. Br J Clin Pharmacol 1980; 10: 109-14
-
(1980)
Br J Clin Pharmacol
, vol.10
, pp. 109-114
-
-
Cusack, B.J.1
Kelly, J.G.2
Lavan, J.3
-
101
-
-
0018869877
-
The effects of age and smoking upon antipyrine metabolism
-
Mucklow JC, Fraser HS. The effects of age and smoking upon antipyrine metabolism. Br J Clin Pharmacol 1980; 9: 63-4
-
(1980)
Br J Clin Pharmacol
, vol.9
, pp. 63-64
-
-
Mucklow, J.C.1
Fraser, H.S.2
-
103
-
-
0016796602
-
Antipyrine metabolism in man: Influence of age, alcohol, caffeine and smoking
-
Vestal RE, Norris AH, Tobin JD, et al. Antipyrine metabolism in man: influence of age, alcohol, caffeine and smoking, Clin Pharmacol Ther 1975; 18: 425-32
-
(1975)
Clin Pharmacol Ther
, vol.18
, pp. 425-432
-
-
Vestal, R.E.1
Norris, A.H.2
Tobin, J.D.3
-
104
-
-
0026409625
-
Human drug abuse liability assessment: Opioids and analgesics
-
Bigelow GE. Human drug abuse liability assessment: opioids and analgesics. Br J Addict 1991; 86: 1615-28
-
(1991)
Br J Addict
, vol.86
, pp. 1615-1628
-
-
Bigelow, G.E.1
-
106
-
-
0024306112
-
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation
-
Yue QY, Svensson JO, Alm C, et al. Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation. Br J Clin Pharmacol 1989; 28: 639-45
-
(1989)
Br J Clin Pharmacol
, vol.28
, pp. 639-645
-
-
Yue, Q.Y.1
Svensson, J.O.2
Alm, C.3
-
107
-
-
0023795013
-
Polymorphic O-demethylation of codeine
-
Chen ZR, Somogyi AA, Bochner F. Polymorphic O-demethylation of codeine. Lancet 1988; 2: 914-5
-
(1988)
Lancet
, vol.2
, pp. 914-915
-
-
Chen, Z.R.1
Somogyi, A.A.2
Bochner, F.3
-
108
-
-
0023931696
-
Pharmacokinetics and pharmacodynamics of codeine in end-stage renal disease
-
Guay DRP, Awni WM, Findlay JWA, et al. Pharmacokinetics and pharmacodynamics of codeine in end-stage renal disease. Clin Pharmacol Ther 1988; 43: 63-71
-
(1988)
Clin Pharmacol Ther
, vol.43
, pp. 63-71
-
-
Guay, D.R.P.1
Awni, W.M.2
Findlay, J.W.A.3
-
109
-
-
0025898644
-
Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: Comparisons between extensive and poor hydroxylators of debrisoquine
-
Yue QY, Hassclström J, Svensson JO, et al. Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine. Br J Clin Pharmacol 1991; 31: 635-42
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 635-642
-
-
Yue, Q.Y.1
Hassclström, J.2
Svensson, J.O.3
-
110
-
-
0024369341
-
Pharmacological characterization of morphine-6β-glucuronide, a very potent morphine metabolite
-
Paul D, Standifer KM, Inturrisi CE, et al. Pharmacological characterization of morphine-6β-glucuronide, a very potent morphine metabolite. J Pharmacol Exp Ther 1989; 251: 477-83
-
(1989)
J Pharmacol Exp Ther
, vol.251
, pp. 477-483
-
-
Paul, D.1
Standifer, K.M.2
Inturrisi, C.E.3
-
111
-
-
0022467935
-
Plasma concentrations of codeine and its metabolite, morphine, after single and repeated oral administration
-
Quiding H, Anderson P, Bondesson U, et al. Plasma concentrations of codeine and its metabolite, morphine, after single and repeated oral administration. Eur J Clin Pharmacol 1986; 30: 673-7
-
(1986)
Eur J Clin Pharmacol
, vol.30
, pp. 673-677
-
-
Quiding, H.1
Anderson, P.2
Bondesson, U.3
-
112
-
-
0001197260
-
Contributo sperimentale all'ipotesi della smetilazione della codeina nell'organismo: I. Influenze della dose sull'assuefazione alla codeina. II. Assuefazione alla codeina attenuta con somministrazione prolungata di morfina
-
Sanfilippo G. Contributo sperimentale all'ipotesi della smetilazione della codeina nell'organismo: I. Influenze della dose sull'assuefazione alla codeina. II. Assuefazione alla codeina attenuta con somministrazione prolungata di morfina. Boll Soc Ital Biol Sper 1948; 24: 723-6
-
(1948)
Boll Soc Ital Biol Sper
, vol.24
, pp. 723-726
-
-
Sanfilippo, G.1
-
113
-
-
0028923152
-
Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan
-
Persson K, Sjöstrom S, Sigurdardottir I, et al. Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan. Br J Clin Pharmacol 1995; 39: 182-6
-
(1995)
Br J Clin Pharmacol
, vol.39
, pp. 182-186
-
-
Persson, K.1
Sjöstrom, S.2
Sigurdardottir, I.3
-
114
-
-
0025868355
-
Impact of environmental and genetic factors on codeine analgesia
-
Desmeules J, Gascon MP, Dayer P, et al. Impact of environmental and genetic factors on codeine analgesia. Eur J Clin Pharmacol 1991; 41: 23-6
-
(1991)
Eur J Clin Pharmacol
, vol.41
, pp. 23-26
-
-
Desmeules, J.1
Gascon, M.P.2
Dayer, P.3
-
115
-
-
0025830147
-
μ-opioid receptor binding affinity of some opiates and their metabolites
-
Irvine RJ, Chen ZR, Somogyi AA, et al. μ-opioid receptor binding affinity of some opiates and their metabolites. Life Sci 1991; 48: 2165-71
-
(1991)
Life Sci
, vol.48
, pp. 2165-2171
-
-
Irvine, R.J.1
Chen, Z.R.2
Somogyi, A.A.3
-
116
-
-
0025649038
-
Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine
-
Sindrup SH, Brosen K, Bjerring P, et al. Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine. Clin Pharmacol Ther 1991; 49: 686-93
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 686-693
-
-
Sindrup, S.H.1
Brosen, K.2
Bjerring, P.3
-
117
-
-
0025149050
-
Plasma codeine and morphine concentrations alter a single oral dose of codeine phosphate
-
Shah JC, Mason WD. Plasma codeine and morphine concentrations alter a single oral dose of codeine phosphate. J Clin Pharmacol 1990; 30: 764-6
-
(1990)
J Clin Pharmacol
, vol.30
, pp. 764-766
-
-
Shah, J.C.1
Mason, W.D.2
-
118
-
-
0023508821
-
Pharmacokinetics of codeine after single- and multiple-oral-dose administration to normal volunteers
-
Guay DRP, Awni WM, Halstenson CE, et al. Pharmacokinetics of codeine after single- and multiple-oral-dose administration to normal volunteers. J Clin Pharmacol 1987; 27: 983-7
-
(1987)
J Clin Pharmacol
, vol.27
, pp. 983-987
-
-
Guay, D.R.P.1
Awni, W.M.2
Halstenson, C.E.3
-
119
-
-
0020328806
-
Patient-controlled analgesic therapy (Pt IV): Pharmacokinetics and analgesic plasma concentrations of morphine
-
Dahlstrom B, Tamsen A, Paalzow L, et al. Patient-controlled analgesic therapy (Pt IV): pharmacokinetics and analgesic plasma concentrations of morphine. Clin Pharmacokinet 1982; 7: 266-79
-
(1982)
Clin Pharmacokinet
, vol.7
, pp. 266-279
-
-
Dahlstrom, B.1
Tamsen, A.2
Paalzow, L.3
-
120
-
-
0021351709
-
Analgesic efficacy after single and repeated doses of codeine and acetaminophen
-
Quiding H, Oikarinen V, Sane J, et al. Analgesic efficacy after single and repeated doses of codeine and acetaminophen. J Clin Pharmacol 1984; 24: 27-34
-
(1984)
J Clin Pharmacol
, vol.24
, pp. 27-34
-
-
Quiding, H.1
Oikarinen, V.2
Sane, J.3
-
121
-
-
0018126174
-
A two dose evaluation of propoxyphene napsylate and codeine in postoperative pain
-
Young RES. A two dose evaluation of propoxyphene napsylate and codeine in postoperative pain. Curr Ther Res 1978; 24: 495-502
-
(1978)
Curr Ther Res
, vol.24
, pp. 495-502
-
-
Young, R.E.S.1
-
122
-
-
0017683075
-
Codeine and propoxyphene in postepisiotomy pain: A two dose evaluation
-
Gruber CM. Codeine and propoxyphene in postepisiotomy pain: a two dose evaluation. JAMA 1977; 237: 2734-2735
-
(1977)
JAMA
, vol.237
, pp. 2734-2735
-
-
Gruber, C.M.1
-
123
-
-
0026669218
-
The analgesic activity of morphine-6-glucuronide
-
Osborne R, Thompson P, Joel S, et al. the analgesic activity of morphine-6-glucuronide. Br J Clin Pharmacol 1992; 34: 130-8
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 130-138
-
-
Osborne, R.1
Thompson, P.2
Joel, S.3
-
124
-
-
0023272780
-
Potential analgesic contribution from morphine-6-glucuronide in CSF
-
Hand CW, Blunnie WP, Claffey LP, et al. Potential analgesic contribution from morphine-6-glucuronide in CSF. Lancet 1987; II: 1207-8
-
(1987)
Lancet
, vol.2
, pp. 1207-1208
-
-
Hand, C.W.1
Blunnie, W.P.2
Claffey, L.P.3
-
125
-
-
0015116683
-
Analgesic effect of morphine glucuronides
-
Shimomura K, Kamata O, Ueki S, et al. Analgesic effect of morphine glucuronides. Tohoku J Exp Med 1971; 105: 45-52
-
(1971)
Tohoku J Exp Med
, vol.105
, pp. 45-52
-
-
Shimomura, K.1
Kamata, O.2
Ueki, S.3
-
126
-
-
0024435591
-
The effect of ageing on the pharmacokinetics of dihydrocodeine
-
Davies KN, Castleden CM, McBurney A, et al. The effect of ageing on the pharmacokinetics of dihydrocodeine. Eur J Clin Pharmacol 1989; 37: 375-9
-
(1989)
Eur J Clin Pharmacol
, vol.37
, pp. 375-379
-
-
Davies, K.N.1
Castleden, C.M.2
McBurney, A.3
-
128
-
-
0023491175
-
Oral administration of codeine in the presence of ethanol: A pharmacokinetic study in man
-
Bodd E, Beylich KM, Christophersen AS, et al. Oral administration of codeine in the presence of ethanol: a pharmacokinetic study in man. Pharmacol Toxicol 1987; 61: 297-300
-
(1987)
Pharmacol Toxicol
, vol.61
, pp. 297-300
-
-
Bodd, E.1
Beylich, K.M.2
Christophersen, A.S.3
-
130
-
-
0022179340
-
A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquine
-
Steiner E, Iselius L, Alvan G, et al. A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquine. Clin Pharmacol Ther 1985; 38: 394-401
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 394-401
-
-
Steiner, E.1
Iselius, L.2
Alvan, G.3
-
131
-
-
0026779189
-
In vitro forecasting of drugs that may interfere with codeine bioactivation
-
Dayer P, Desmeules J, Striberni R. In vitro forecasting of drugs that may interfere with codeine bioactivation. Eur J Drug Metab Pharmacokinet 1992; 17: 115-20
-
(1992)
Eur J Drug Metab Pharmacokinet
, vol.17
, pp. 115-120
-
-
Dayer, P.1
Desmeules, J.2
Striberni, R.3
-
132
-
-
10344230639
-
Developing medication strategies as adjuncts to treating prescription opiate dependence and comorbidity
-
Harris LS, editor. Problems of drug dependence. Rockville: US Department of Health and Human Services
-
Romach MK, Sproule B, Kathiramalainathan K, et al. Developing medication strategies as adjuncts to treating prescription opiate dependence and comorbidity. In: Harris LS, editor. Problems of drug dependence. Proceedings of the 57th Annual Scientific Meeting of the College on Problems of Drug Dependence. Rockville: US Department of Health and Human Services, 1996: 120
-
(1996)
Proceedings of the 57th Annual Scientific Meeting of the College on Problems of Drug Dependence
, pp. 120
-
-
Romach, M.K.1
Sproule, B.2
Kathiramalainathan, K.3
-
133
-
-
0026673808
-
Management of behavior disturbance in Alzheimer disease: Current knowledge and future direction
-
Teri L, Rabins P, Whitehouse P, et al. Management of behavior disturbance in Alzheimer disease: current knowledge and future direction. Alzheimer Dis Assoc Disord 1992; 6: 77-88
-
(1992)
Alzheimer Dis Assoc Disord
, vol.6
, pp. 77-88
-
-
Teri, L.1
Rabins, P.2
Whitehouse, P.3
-
135
-
-
0023272506
-
Behavioral symptoms in Alzheimer's disease: Phenomenology and treatment
-
Reisberg B, Borenstein J, Salob SP, et al. Behavioral symptoms in Alzheimer's disease: phenomenology and treatment. J Clin Psychiatry 1987; 48 Suppl. 5: 9-15
-
(1987)
J Clin Psychiatry
, vol.48
, Issue.5 SUPPL.
, pp. 9-15
-
-
Reisberg, B.1
Borenstein, J.2
Salob, S.P.3
-
137
-
-
0025305464
-
The genetic polymorphism of debrisoquine/sparteine metabolism - Clinical aspects
-
Eichelbaum M, Gross AS. The genetic polymorphism of debrisoquine/sparteine metabolism - clinical aspects. Pharmacol Ther 1990; 46: 377-94
-
(1990)
Pharmacol Ther
, vol.46
, pp. 377-394
-
-
Eichelbaum, M.1
Gross, A.S.2
-
138
-
-
0026610576
-
Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population
-
Dahl ML, Johansson I, Palmertz MP, et al. Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population. Clin Pharmacol Ther 1992; 51: 12-7
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 12-17
-
-
Dahl, M.L.1
Johansson, I.2
Palmertz, M.P.3
-
139
-
-
0028942981
-
Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
-
Agundez JA, Ledesma MC, Ladero JM, et al. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995; 57: 265-9
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 265-269
-
-
Agundez, J.A.1
Ledesma, M.C.2
Ladero, J.M.3
-
140
-
-
0029064096
-
Ultrarapid hydroxylation of debrisoquine in a Swedish population: Analysis of the molecular genetic basis
-
Dahl M-L, Johansson I, Bertilsson L, et al. Ultrarapid hydroxylation of debrisoquine in a Swedish population: analysis of the molecular genetic basis. J Pharmacol Exp Ther 1995; 274: 516-20
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 516-520
-
-
Dahl, M.-L.1
Johansson, I.2
Bertilsson, L.3
-
141
-
-
0027534276
-
Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine
-
Bertilsson L, Dahl M-L, Sjöqvist F, et al. Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine. Lancet 1993; 341: 63
-
(1993)
Lancet
, vol.341
, pp. 63
-
-
Bertilsson, L.1
Dahl, M.-L.2
Sjöqvist, F.3
-
142
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450 CYP2D-locus as a cause of ultrarapid metabolism of debrisoquine
-
Johansson I, Lundqvist E, Bertilsson L, et al. Inherited amplification of an active gene in the cytochrome P450 CYP2D-locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 1993; 90: 11825-9
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11825-11829
-
-
Johansson, I.1
Lundqvist, E.2
Bertilsson, L.3
-
143
-
-
0025736774
-
A comparison of the pharmacokinetics of codeine and its metabolites in healthy Chinese and Caucasian extensive hydroxylators of debrisoquine
-
Yue QY, Svensson JO, Sjöqvist F, et al. A comparison of the pharmacokinetics of codeine and its metabolites in healthy Chinese and Caucasian extensive hydroxylators of debrisoquine. Br J Clin Pharmacol 1991; 31: 643-7
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 643-647
-
-
Yue, Q.Y.1
Svensson, J.O.2
Sjöqvist, F.3
-
144
-
-
0026031652
-
Interethnic variation of drug metabolism
-
Kalow W. Interethnic variation of drug metabolism. Trends Pharmacol Sci 1991; 12: 102-7
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 102-107
-
-
Kalow, W.1
|