CD28 signal transduction pathways. A comparison of B7-1 and B7-2 regulation of the MAP kinases: ERK2 and Jun kinases

Molecular Immunology

Volumn 33, Issue 1, 1996, Pages 63-70

  Nunès, Jacques A ^a,e   Battifora, Michaela ^b   Woodgett, James R ^c   Truneh, Alemseged ^d   Olive, Daniel ^b   Cantrell, Doreen A ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b INSERM   (France)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d GLAXOSMITHKLINE   (United Kingdom)

^e CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

Author keywords

B7 1; B7 2; Jun kinases; Signal transduction

Indexed keywords

CD28 ANTIGEN; CD86 ANTIGEN; PROTEIN KINASE; PROTEIN KINASE C;

ARTICLE; CELL LINE; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0029970295     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(95)00121-2     Document Type: Article

References (39)

1. Azuma M., Ito D., Yagita H., Okumura K., Phillips J. S., Lanier L. L. and Somoza C. (1993) B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366, 76-79.
2. Caux C., Vanbervliet B., Massacrier C., Azuma M., Okumura K., Lanier L. L. and Banchereau J. (1994) B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J. Exp. Med. 180, 1841-1848.
3. Crabtree G. R. (1989) Contingent genetic regulatory events in T lymphocyte activation. Science 243, 355-361.
4. Dai T., Rubie E. A., Franklin C. C., Kraft A., Gillepsie D. A. F., Avruch J., Kyriakis J. A. and Woodgett J. R. (1995) Stress-activated protein kinases bind directly to the δ domain of c-Jun in resting cells: implications for repression of C-Jun function. Oncogene 10, 849-855.
5. Dérijard B., Hibi M., Wu I.-H., Barett T., Su B., Deng T., Karin M. and Davis R. J. (1994) JNK-1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
6. Dérijard B., Raingeaud J., Barrett T., Wu I.-H., Han J., Ulevitch R. J. and Davis R. J. (1995) Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267, 682-685.
7. Engel P., Gribben J. G., Freeman G. J., Zhou L.-J., Nozawa Y., Abe M., Nadler L. M., Wakasa H. and Tedder T. F. (1994) The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood 84, 1402-1407.
8. Freeman G. J., Borriello F., Hodes R. J., Reiser H., Hathcock K. S., Laszlo G., McKnight A. J., Kim J., Du L., Lombard D. B., Gray G. S., Nadler L. M. and Sharpe A. H. (1993a) Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262, 907-909.
9. Freeman G. J., Gribben J. G., Boussiotis V. A., Ng J. W., Restivo V. A., Lombard L. A., Gray G. S. and Nadler L. M. (1993b) Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262, 909-911.
10. Freeman G. J., Boussiotis V. A., Anumenihan A., Berstein G. M., Ke X.-Y., Rennert P. D., Gray G. S., Gribben J. G. and Nadler L. M. (1995) B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2, 523-532.
11. Hathcock K. S., Laszlo G., Dickler H. B., Bradshaw J., Linsley P. and Hodes R. J. (1993) Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262, 905-907.
12. Izquierdo M., Bowden S. and Cantrell D. (1994) The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor. J. Exp. Med. 180, 401-406.
13. ras regulatory pathways coexist in T cells. Mol. Cell. Biol. 12, 3305-3312.
14. ras Couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes. J. Exp. Med. 178, 1199-1208.
15. Kuchroo V. K., Prabhu Das M., Brown J. A., Ranger A. M., Zamvil S. S., Sobel R. A., Weiner H. L., Nabavi N. and Glimcher L. H. (1995) B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80, 707-718.
16. Kyriakis J. M., Banerjee P., Nikolakaki E., Dai T., Rubie E. A., Ahmad M. F., Avruch J. and Woodgett J. R. (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
17. Lanier L. L., O'Fallon S., Somoza C., Phillips J. H., Linsley P. S., Okumura K., Ito D. and Azuma M. (1995) CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J. Immun. 154, 97-105.
18. ras oncoproteins. EMBO J. 11, 569-574.
19. Lenschow D. J., Ho S. C., Sattar H., Rhee L., Gray G., Nabavi N., Herold K. C. and Bluestone J. A. (1995) Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the non-obese diabetic mouse. J. Exp. Med. 181, 1145-1155.
20. Lin A., Minden A., Martinetto H., Claret F.-X., Lange-Carter C., Mercurio F., Johnson G. L. and Karin M. (1995) Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268, 286-290.
21. Linsley P. S., Clark E. A. and Ledbetter J. A. (1990) T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc. natn. Acad. Sci. USA 87, 5031-5036.
22. Linsley P. S., Greene J. L., Brady W., Bajorah J., Ledbetter J. A. and Peach R. (1994) Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but with distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1, 793-801.
23. Linsley P. S. and Ledbetter J. A. (1993) The role of the CD28 receptor during T cell responses to antigen. A. Rev. Immun. 11, 191-212.
24. Minden A., Lin A., McMahon M., Lange-Carter C., Dérijard B., Davis R. J., Johnson G. L. and Karin M. (1994) Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 266, 1719-1723.
25. Nunès J., Klasen S., Ragueneau M., Pavon C., Couez D., Mawas C. and Olive D. (1993) CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events. Int. Immun. 5, 311-315.
26. ras. J. Exp. Med. 180, 1067-1076.
27. Rincòn M. and Flavell R. A. (1994) AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J. 13, 4370-4381.
28. Samuels M. L., Weber M. J., Bishop M. J. and McMahon M. (1993) Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an oestradiol dependent human Raf-1 protein kinase. Mol. Cell. Biol. 13, 6241-6248.
29. Sanchez I., Hughes R. T., Mayer B. J., Yee K., Woodgett J. R., Avruch J., Kyriakis J. M. and Zon L. I. (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372, 794-798.
30. Siegel J. N., June C. H., Yamada H., Rapp U. R. and Samelson L. (1993) Rapid activation of c-Raf-1 after stimulation of the T-cell receptor or the muscarinic receptor type 1 in resting T cells. J. Immun. 151, 4116-4127.
31. Siegel J. N., Klausner R. D., Rapp U. R. and Samelson L. E. (1990) T cell antigen receptor engagement stimulates c-raf kinase activity via a protein kinase C-dependent pathway. J. Biol. Chem. 265, 18472-18480.
32. Sozeri O., Kerstin M., Liyanage D., Frith D., Kour G., Mark G. E. and Stabel S. (1992) Activation of the c-Raf protein kinase by protein kinase C phosphorylation. Oncogene 7, 2259-2262.
33. Su B., Jacinto E., Hibi M., Kallunki T., Karin M. and Ben-Neriah Y. (1994) JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77, 727-736.
34. Ueda Y., Levine B. L., Huang M. L., Freeman G. J., Nadler L. M., June C. H. and Ward S. G. (1995) Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion. Int. Immun. 7, 957-966.
35. van Seventer G. A., Shimizu Y. and Shaw S. (1991) Roles of multiple accessory molecules in T cell activation. Curr. Opin. Immun. 3, 294-303.
36. Ward S. G., Westwich J., Hall N. D. and Sansom D. M. (1993) Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation. Eur. J. Immun. 23, 2572-2577.
37. Weiss A. and Littman D. R. (1994) Signal transduction by lymphocyte antigen receptor. Cell 76, 263-274.
38. Yan M., Dai T., Deak J. C., Kyriakis J. M., Zon L. I., Woodgett J. R. and Templeton D. J. (1994) Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature 372, 798-800.
39. Zmuidzinas A., Mamom H. J., Roberts T. and Smith K. A. (1991) Interleukin-2-triggered Raf-1 expression, phosphorylation, and associated kinase activity increase through G1 and S in CD3-stimulated primary human T cells. Mol. Cell. Biol. 11, 2794-2803.