Bilirubin-oxidizing activity in rat brain

Neonatology

Volumn 70, Issue 5, 1996, Pages 289-295

  Hansen, Thor Willy Ruud ^a,b   Allen, Jeffrey W ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Bilirubin encephalopathy; Bilirubin oxidation; Brain; Kernicterus; Mitochondria

Indexed keywords

BILIRUBIN;

ANIMAL TISSUE; ARTICLE; BILIRUBIN METABOLISM; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN METABOLISM; BRAIN REGION; CEREBELLUM; CEREBROSPINAL FLUID; CONTROLLED STUDY; CORPUS STRIATUM; DRUG OXIDATION; HIPPOCAMPUS; HYPOTHALAMUS; KERNICTERUS; MESENCEPHALON; MITOCHONDRIAL MEMBRANE; NONHUMAN; OPTICAL DENSITY; PH; PRIORITY JOURNAL; RAT; TEMPERATURE SENSITIVITY;

ANIMALS; BILIRUBIN; BRAIN; CEREBELLUM; CEREBRAL CORTEX; HEAT; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; MEDULLA OBLONGATA; MESENCEPHALON; MITOCHONDRIA; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0029969862     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000244378     Document Type: Article

References (28)

1. Maisels MJ: Jaundice; in Avery GB, Fletcher MA, MacDonald MG (eds): Neonatology: Pathophysiology and Management of the Newborn, ed 4. Philadelphia, Lippincott, 1994, pp 630-725.
2. Perlstein MA: The late clinical syndrome of posticteric encephalopathy. Pediatr Clin North Am 1960,7: 665-687.
3. l4C-bilirubin in congenital nonhemolytic jaundice. J Clin Invest 1963:42:1720-1734.
4. Brodersen R, Bartels P: Enzymatic oxidation of bilirubin. Eur J Bio-chem 1969;10:468-473.
5. Yokosuka O, Billing B: Enzymatic oxidation of bilirubin by intestinal mucosa. Biochim Biophys Acta 1987;923:268-274.
6. Mullon CJ-P, Langer R: Determination of conjugated and total bilirubin in serum of neonates, with use of bilirubin oxidase. Clin Chem 1987; 33:1822-1825.
7. Perry B, Doumas BT, Buffone G, Glick M, Ou C-N, Ryder K: Measurement of total bilirubin by use of bilirubin oxidase. Clin Chem 1986; 32:329-332.
8. Doumas BT, Perry B, Jendrzcjczak B, Davis L: Measurement of direct bilirubin by use of bilirubin oxidase. Clin Chem 1987;33:1349-1353.
9. Lavin A, Sung C, Klibanov AM, Langer R: Enzymatic removal of bilirubin from blood: A potential treatment for neonatal jaundice. Science 1985;230:543-545.
10. Sung C, Lavin A, Klibanov AM, Langer R: An immobilized enzyme reactor for the detoxification of bilirubin. Biotech Bioeng 1986;28: 1531-1539.
11. Sugi K, Inoue M, Morino Y: Degradation of plasma bilirubin by a bilirubin oxidase derivative which has a relatively long half-life in the circulation. Biochim Biophys Acta 1989; 991:405-409.
12. Burgess GH, Oh W, Bratlid D, Brubakk A-M, Cashore WJ, Stonestreet BS: The effects of brain blood flow on brain bilirubin deposition in newborn piglets. Pediatr Res 1985; 19:691-696.
13. Burgess GH, Stonestreet BS, Cashore WJ, Oh W: Brain bilirubin deposition and brain blood flow during acute urea-induced hyperosmolality in newborn piglets. Pediatr Res 1985;19:537-542.
14. Hansen TWR, Oyasteter S, Stiris T, Bratlid D: Effects of sulfisoxazole, hypercarbia, and hyperosmolality on entry of bilirubin and albumin into young rat brain regions. Biol Neonate 1989;56:22-30.
15. Hansen TWR: Acute entry of bilirubin into rat brain regions. Biol Neonate 1995;67:203-207.
16. Hansen TWR, CashoreWJ: Rates of bilirubin clearance from rat brain regions. Biol Neonate 1995;68:135-140.
17. Hansen TWR: Bilirubin entry into and clearance from rat brain during hypercarbia and hyperosmolality. Pediatr Res 1996;39:1-6.
18. Levine RL, Fredericks WR, Rapo-port SI: Entry of bilirubin into the brain due to opening of the blood-brain barrier. Pediatrics 1982;69: 255-259.
19. Brodersen R, Stem L: Deposition of bilirubin acid in the central nervous system - A hypothesis for the development of kern icterus. Acta Pacdiatr Scand 1990;79:12-19.
20. Whittaker VP, Barker LA: The sub-cellular fractionation of brain tissue with special reference to the preparation of synaptosomes and their component organelles; in Fried R (cd): Methods of Neurochemistry. New York, Dekker, 1972, vol 2, pp 1-52.
21. Glowinski J, Ivcrsen LL: Regional studies of catecholamines in the rat brain. Part I. J Neurochem 1966; 13: 655-669.
22. Hansen TWR, Bratlid D: Cerebral blood volumes in young rats with and without in situ flushing of cerebral vasculature: Implications for in vivo studies of brain substance uptake. Biol Neonate 1989;56:15-21.
23. Jacobsen J, Wennberg RP: Determination of unbound bilirubin in the serum of newborns. Clin Chem 1974;20:783-789.
24. Hansen TWR, Allen JW: Hemolytic anemia does not increase entry into, nor alter rate of clearance of bilirubin from rat brain. Biol Neonate 1996;69:268-274.
25. Robinson PJ, Rapoport SI: Binding effect of albumin on uptake of bilirubin by brain. Pediatrics 1987;79: 553-558.
26. Lcong SF, Lai JCK, Lint L, Clark JB: The activities of some energy-metabolizing enzymes in nonsynap-tic (free) and synaptic mitochondria derived from selected brain regions. J Neurochem 1984;42:1306-1312.
27. Leung TK, Lim L, Lai JC: Brain regional distributions of monoamine oxidase activities in postnatal development in normal and chronically manganese-treated rats. Metab Brain Dis 1993;8:137-149.
28. Lai JC, Leung TK, Lim L: Heterogeneity of monoamine oxidase activities in synaptic and non-synaptic mitochondria derived from three brain regions: Some functional implications. Metab Brain Dis 1994;9: 53-66.