Synthesis, reactivity and 99mTc labelling of 2-alkoxyisobutylisonitrile

Applied Radiation and Isotopes

Volumn 47, Issue 2, 1996, Pages 207-210

  Lee, Te Wei ^a   Su, Chang Shinn ^a   Ting, Gann ^a  

^a INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 ALKOXYISOBUTYLISONITRILE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HEART SCINTISCANNING; ISOTOPE LABELING; PRIORITY JOURNAL;

EID: 0029969481     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/0969-8043(95)00249-9     Document Type: Article

References (6)

1. Holman B. L., Jones A. G., Lister-James J., Davison A., Abrams M. J., Kirschenbaum J. M., Tumeh S. S. and English R. J. (1984) A new Tc-99m-labelled myocardial imaging agent, hexakis (t-butylisonitrole)-technetium(I)[Tc-99m-TBI]: initial experience in the human. J. Nucl. Med. 25, 1350.
2. Holman B. L., Sporn V., Jones A. G., Benjamin S. T., Perez-Balino N., Davison A., Lister-James J., Kronauge J. F., Mitta A. E. A., Camin L. L., Campbell S., Williams S. J. and Carpenter A. T. (1987) Myocardial imaging with technetium-99m CPI: initial experience in the human. J. Nucl. Med. 28, 13.
3. McKusick K. (1986) Comparison of three Tc-99m isonitriles for detection of ischemic heart disease in humans. J. Nucl. Med. 27, 878.
4. McKusick K., Beller G., Berman D. et al. (1987) Initial clinical results with Tc-99m methoxy isobutyl isonitrile. J. Am. Coll. Cardiol. 9, 28A.
5. Mousa S., Maina M., Brown B. A. et al. (1987) Retention of RP-30 in the heart may be due to binding to a cytosolic protein. J. Nucl. Med. 28, 619.
6. Weber W. P. and Gokel G. W. (1972) An improved procedure for Hofmann carbylamine synthesis of isonitriles. Tetrahedron Lett. 17, 1637.