Metabolism of tamsulosin in rat and dog

Xenobiotica

Volumn 26, Issue 3, 1996, Pages 355-365

  Soeishi, Y ^a   Matsushima, H ^a   Teraya, Y ^a   Watanabe, T ^a   Higuchi, S ^a   Kaniwa, H ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; DRUG METABOLITE; TAMSULOSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; DRUG METABOLISM; INTESTINE; KIDNEY; LIVER; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SPECIES DIFFERENCE; URINE;

ANIMALIA; CANIS FAMILIARIS;

EID: 0029969208     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.3109/00498259609046714     Document Type: Article

References (7)

1. 1-Adrenoceptor antagonist effects of optical isomers of YM-12617 in rabbit lower urinary tract and prostate. Journal of Pharmacology and Experimental Therapeutics, 239, 512-516.
2. 1-adrenoceptor antagonist and its individual optical enantiomers. Naunyn-Schmiedeberg's Archives of Pharmacology, 336, 295-302.
3. KAMIMURA, H., SASAKI, H., and KAWAMURA, S., 1985, Metabolism of amosulalol hydrochloride in man, quantitative comparison with laboratory animals. Xenobiotica, 15, 413-420.
4. SASAKI, H., KAMIMURA, H., KANIWA, H., and KAWAMURA, S., 1984, Disposition and metabolism of amosulalol hydrochloride, a new combined α- and β-adrenoceptor blocking agent, in rats, dogs and monkeys. Xenobiotica, 14, 621-631.
5. 14C-amsulosin hydrochloride in rats and dogs. Pharmacometrics (Oyo Yakuri), 40, 101-109.
6. SOEISHI, Y., KOBORI, M., KOBAYASHI, S., and HIGUCHI, S., 1990b, Sensitive method for the determination of amsulosin in human plasma using high-performance liquid chromatography with fluorescence detection. Journal of Chromatography, Biomedical Applications, 533, 291-296.
7. YAMADA, S., ASHIZAWA, N., USHIJIMA, H., NAKAYAMA, K., HAYASHI, E., and HONDA, K., 1987, Alpha-1 adrenoceptors in human prostate. Characterization and alteration in benign prostatic hypertrophy. Journal of Pharmacology and Experimental Therapeutics, 242, 326-330.