Intrinsic solubility estimation and pH-solubility behavior of cosalane (NSC 658586), an extremely hydrophobic diprotic acid

Pharmaceutical Research

Volumn 13, Issue 10, 1996, Pages 1453-1459

  Venkatesh, Srinivasan ^a,b   Li, Jianmin ^a,c   Xu, Yuehong ^a   Vishnuvajjala, Rao ^d   Anderson, Bradley D ^a  

^a UNIVERSITY OF UTAH   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c INOVA DIAGNOSTICS INC   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cosalane; Facilitated dissolution; Group contribution approach; Partition coefficient; pH solubility behavior; Solubility

Indexed keywords

ANTIVIRUS AGENT; COSALANE; UNCLASSIFIED DRUG;

ARTICLE; DISSOLUTION; DRUG SOLUBILITY; MOLECULAR DYNAMICS; PARTITION COEFFICIENT; PH; PRIORITY JOURNAL;

ANTI-HIV AGENTS; AURINTRICARBOXYLIC ACID; CHEMISTRY, PHYSICAL; HYDROGEN-ION CONCENTRATION; IONS; KINETICS; SOLUBILITY;

EID: 0029969048     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016059008464     Document Type: Article

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