Continuous measurement of changes in regional cerebral blood flow following cortical compression contusion trauma in the rat

Journal of Neurotrauma

Volumn 13, Issue 4, 1996, Pages 201-207

  Nilsson, Pelle ^a   Gazelius, Bertil ^b   Carlson, Hans ^a   Hillered, Lars ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

cerebral contusion; conical spreading depression; laser Doppler flowmetry; rCBF; TBI

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BRAIN BLOOD FLOW; BRAIN CONTUSION; BRAIN PERFUSION; CONTROLLED STUDY; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; RAT; SPREADING CORTICAL DEPRESSION;

EID: 0029968835     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1996.13.201     Document Type: Article

References (26)

1. ASTRUP, J., SIESJÖ, B.K., and SIMON, L. (1981). Thresholds in cerebral ischemia-the ischemic penumbra. Stroke 12, 723-725.
2. CORTEZ, S.C., MCINTOSH, T.K., and NOBLE, L.J. (1989). Experimental fluid percussion brain injury: Vascular disruption and neuronal and glial alterations. Brain Res. 482, 271-282.
3. DEWITT, D.S., JENKINS, L.W., WEI, E.P., LUTZ, H., BECKER, D.P., and KONTOS, H.A. (1986). Effects of fluid-percussion brain injury on regional cerebral blood flow and pial aneriolar diameter. J. Neurosurg. 64, 787-794.
4. DIRNAGL, U., KAPLAN, B., JACEWICZ, M., and PULSINELLI, W. (1989). Continuous measurement of cerebral cortical blood flow by laser-doppler flowmetry in a rat stroke model. J. Cereb. Blood Flow Metab. 9, 589-596.
5. DUCKROW, R.B. (1991). Regional cerebral blood flow during spreading cortical depression in conscious rats. J. Cereb. Blood Flow Metab. 11, 150-154.
6. FEENEY, D.M., BOYESON, M.G., LINN, R.T., MURRAY. H.M., and DAIL, W.G. (1981). Responses to cortical injury. I. Methodology and local effects of contusions in the rat. Brain Res. 211, 67-77.
7. HANSEN, A.J. (1985). Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65, 101-148.
8. HEKMATPANAH, J., and HEKMATPANAH, C.R. (1985). Microvascular alterations following cerebral contusion in rats. Light, scanning, and electronmicroscope study. J. Neurosurg. 62, 888-897.
9. 2 response. J. Cereb. Blood Flow Metab. 4, 546-554.
10. LAURITZEN, M., JORGENSEN, M.B., DIEMER, N.H., GJEDDE, A., and HANSEN, A.J. (1982). Persistent oligemia of rat cerebral cortex in the wake of spreading depression. Ann. Neurol. 12, 469-474.
11. LEAO, A.P.P. (1944). Spreading depression of activity in cerebral cortex. J. Neurophysiol. 7, 359-390.
12. MILLER, J.D., BULLOCK, R., GRAHAM, D.I., CHEN, M-H., and TEASEDALE, G.M. (1990). Ischemic brain damage in a model of acute subdural hematoma. Neurosurgery 27, 433-439.
13. MUIR, J.K., BOERSCHEL, M., and ELLIS, E.F. (1992). Continuous monitoring of posttraumatic cerebral blood flow using laser-doppler flowmetry. J. Neurotrauma 9, 355-362.
14. NILSSON, B., and NORDSTROM, C.H. (1977). Experimental head injury in the rat. Part 3: Cerebral blood flow and oxygen consumption after concussive impact acceleration. J. Neurosurg. 47, 262-273.
15. 2+ levels following cortical compression contusion trauma in rats. J. Cereb. Blood Flow Metab. 13, 183-192.
16. NILSSON, P., HILLERED, L., PONTÉN, U., and UNGERSTEDT, U. (1990). Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats. J. Cereb. Blood Flow Metab. 10, 631-637.
17. NILSSON, P., LAURSEN, H., HILLERED, L., and HANSEN, A.J. (1996). Calcium movements in traumatic brain injury: The role of glutamate receptor-operated ion channels. J. Cereb. Blood Flow Metab. 16, 262-270.
18. NILSSON, P., RONNE-ENGSTRÖM, E., FLINK, R., UNGERSTEDT, U., CARLSON, H., and HILLERED, L. (1994). Epileptic seizure activity in the acute phase following cortical impact trauma in rat. Brain Res. 637, 227-232.
19. 2. J. Neurosurg. 51, 18-26.
20. SOLOMON, R.A., ANTUNES, J.L., CHEN, R.Y.Z., BLAND, L., and CHIEN, S. (1985). Decrease in cerebral blood flow in rats after experimental subarachnoid hemorrhage: A new animal model. Stroke 16, 58-64.
21. TANNO, H., NOCKELS, R.P., PITTS, L.H., and NOBLE, L.J. (1992). Breakdown of the blood-brain barrier after fluid percussion brain injury in the rat. Part 1: Distribution and time course of protein extravasation. J. Neurotrauma 1, 21-32.
22. TORNHEIM, P.A., and MCLAURIN, R.L. (1981). Acute changes in regional brain water content following experimental closed head injury. J. Neurosurg. 55, 407-413.
23. TORNHEIM, P.A., PRIOLEAU, G.R., and MCLAURIN, R.L. (1984). Acute responses to experimental blunt head trauma: Topography of cerebralcortical edema. J. Neurosurg. 60, 473-480.
24. YAMAKAMI, I., and MCINTOSH, T.K. (1989). Effects of traumatic brain injury on regional cerebral blood flow in rats as measured with radioiabeled microspheres. J. Cereb. Blood Flow Metab. 9, 117-124.
25. YAMAKAMI, L. and McINTOSH, T.K. (1991). Alterations in regional cerebral blood flow following brain injury in the rat. J. Cereb. Blood Flow Metab. 11, 655-660.
26. YUAN, X-Q., PROUGH, D.S., SMITH, T.L., and DEWITT, D.S. (1988). The effect of traumatic brain injury on regional cerebral blood flow in rats. J. Neurotrauma 5, 289-301.