Mutations in the gene for human dihydrofolate reductase: An unlikely cause of clinical relapse in pediatric leukemia after therapy with methotrexate

Leukemia

Volumn 10, Issue 3, 1996, Pages 439-446

  Spencer, H T ^a   Sorrentino, B P ^a   Pui, C H ^a,b   Chunduru, S K ^a   Sleep, S E H ^a   Blakley, R L ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

Acute lymphoblastic leukemia; Bone marrow; Resistance; Retrovirus

Indexed keywords

ASPARAGINASE; CYTARABINE; DAUNORUBICIN; DIHYDROFOLATE REDUCTASE; ENZYME VARIANT; FOLINIC ACID; MERCAPTOPURINE; MESSENGER RNA; METHOTREXATE; PREDNISONE; TENIPOSIDE; VINCRISTINE;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; BONE MARROW CELL; CANCER RECURRENCE; CATALYSIS; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; EXPRESSION VECTOR; FEMALE; FIBROBLAST; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; INFANT; MALE; PRIORITY JOURNAL; RETROVIRUS; REVERSE TRANSCRIPTION; SITE DIRECTED MUTAGENESIS; STEM CELL;

EID: 0029968425     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

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